[1]JustusLiebigsAnnalenderChemie,1958,vol.618,p.210,215,219
[1]Lohmann;Schuster[BiochemischeZeitschrift,1937,vol.294,p.188,199]Karrer;Viscontini[HelveticaChimicaActa,1946,vol.29,p.711,715]
[1]Lohmann;Schuster[BiochemischeZeitschrift,1937,vol.294,p.188,199]Karrer;Viscontini[HelveticaChimicaActa,1946,vol.29,p.711,715]
[1]Lohmann;Schuster[BiochemischeZeitschrift,1937,vol.294,p.188,199]Karrer;Viscontini[HelveticaChimicaActa,1946,vol.29,p.711,715]
[1]Lohmann;Schuster[BiochemischeZeitschrift,1937,vol.294,p.188,199]Karrer;Viscontini[HelveticaChimicaActa,1946,vol.29,p.711,715]
Title: Chemical and genetic validation of thiamine utilization as an antimalarial drug target.
Journal: Nature communications 20130101
Title: Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.
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Title: Thiamine deficiency in Cambodian infants with and without beriberi.
Journal: The Journal of pediatrics 20121101
Title: Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamate.
Journal: Biochemistry 20121009
Title: Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues.
Journal: Organic & biomolecular chemistry 20120814
Title: Altered expression and activities of enzymes involved in thiamine diphosphate biosynthesis in Saccharomyces cerevisiae under oxidative and osmotic stress.
Journal: FEMS yeast research 20120801
Title: Decarboxylation mechanisms in biological system.
Journal: Bioorganic chemistry 20120801
Title: A high-affinity and specific carrier-mediated mechanism for uptake of thiamine pyrophosphate by human colonic epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120801
Title: Computer-assisted study on the reaction between pyruvate and ylide in the pathway leading to lactyl-ThDP.
Journal: Journal of computer-aided molecular design 20120801
Title: Identification of mitochondrial thiamin diphosphate carriers from Arabidopsis and maize.
Journal: Functional & integrative genomics 20120601
Title: Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family.
Journal: The FEBS journal 20120401
Title: Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.
Journal: Journal of the American Chemical Society 20120227
Title: Effects of free Ca²⁺ on kinetic characteristics of holotransketolase.
Journal: The protein journal 20120201
Title: kinITC: a new method for obtaining joint thermodynamic and kinetic data by isothermal titration calorimetry.
Journal: Journal of the American Chemical Society 20120111
Title: Thiamine diphosphate in whole blood, thiamine and thiamine monophosphate in breast-milk in a refugee population.
Journal: PloS one 20120101
Title: Altered heavy metals and transketolase found in autistic spectrum disorder.
Journal: Biological trace element research 20111201
Title: Role of thiamine in Alzheimer's disease.
Journal: American journal of Alzheimer's disease and other dementias 20111201
Title: Density-functional study on the equilibria in the ThDP activation.
Journal: Journal of molecular modeling 20111101
Title: Thiamine supplementation in the critically ill.
Journal: Current opinion in clinical nutrition and metabolic care 20111101
Title: Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.
Journal: Nature 20111027
Title: Cell damage through pentose phosphate pathway in fetus fibroblast cells exposed to methyl mercury.
Journal: Journal of applied toxicology : JAT 20111001
Title: Role of thiamine pyrophosphate in oligomerisation, functioning and import of peroxisomal 2-hydroxyacyl-CoA lyase.
Journal: Biochimica et biophysica acta 20111001
Title: Enzymatic probing analysis of an engineered riboswitch reveals multiple off conformations.
Journal: Nucleosides, nucleotides & nucleic acids 20110901
Title: The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase.
Journal: Rejuvenation research 20110801
Title: Acetyl-CoA metabolism in amprolium-evoked thiamine pyrophosphate deficits in cholinergic SN56 neuroblastoma cells.
Journal: Neurochemistry international 20110801
Title: Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae.
Journal: The FEBS journal 20110601
Title: Tomato LeTHIC is an Fe-requiring HMP-P synthase involved in thiamine synthesis and regulated by multiple factors.
Journal: Plant & cell physiology 20110601
Title: Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels.
Journal: Journal of neurochemistry 20110601
Title: Preliminary X-ray crystallographic studies of the catalytic subunit of Escherichia coli AHAS II with its cofactors.
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20110601
Title: Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients?
Journal: Medical hypotheses 20110501
Title: Construction of a thiamine pyrophosphate high-producing strain of Aspergillus oryzae by overexpression of three genes involved in thiamine biosynthesis.
Journal: Journal of bioscience and bioengineering 20110401
Title: Thermodynamic examination of the pyrophosphate sensor helix in the thiamine pyrophosphate riboswitch.
Journal: RNA (New York, N.Y.) 20110401
Title: Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches.
Journal: Biochemical Society transactions 20110401
Title: Thiamine (vitamin B1) concentrations in a population of Australians with alcohol use disorders are remarkably elevated.
Journal: The Medical journal of Australia 20110307
Title: Solid-state NMR and density functional theory studies of ionization states of thiamin.
Journal: The journal of physical chemistry. B 20110203
Title: RNA networks in prokaryotes I: CRISPRs and riboswitches.
Journal: Advances in experimental medicine and biology 20110101
Title: [Measurement of thiamine concentration in the cat using high pressure liquid chromatography].
Journal: Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere 20110101
Title: Modifications of a calcium phosphate cement with biomolecules--influence on nanostructure, material, and biological properties.
Journal: Journal of biomedical materials research. Part A 20101201
Title: Functional nonequivalence of transketolase active centers.
Journal: IUBMB life 20101101
Title: Crystal structures of phosphoketolase: thiamine diphosphate-dependent dehydration mechanism.
Journal: The Journal of biological chemistry 20101029
Title: A general approach to the construction of structure-switching reporters from RNA aptamers.
Journal: Angewandte Chemie (International ed. in English) 20101018
Title: Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in Bifidobacterium.
Journal: FEBS letters 20100924
Title: Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate .
Journal: Biochemistry 20100921
Title: Inhibition of transketolase by hexacyanoferrate(III).
Journal: Biochemistry. Biokhimiia 20100801
Title: Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.
Journal: Investigative ophthalmology & visual science 20100601
Title: New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli.
Journal: The FEBS journal 20100601
Title: Computational study on the carboligation reaction of acetohidroxyacid synthase: new approach on the role of the HEThDP- intermediate.
Journal: Proteins 20100515
Title: Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a 'direct pathway' between the 4'-aminopyrimidine N1' atoms.
Journal: The Journal of biological chemistry 20100409
Title: Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous alpha-ketoglutarate-decarboxylating enzymes.
Journal: Biochemistry 20100330
Title: The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster.
Journal: The FEBS journal 20100301
Title: The ligand-free state of the TPP riboswitch: a partially folded RNA structure.
Journal: Journal of molecular biology 20100212
Title: Early metabolic reactivation versus antioxidant therapy after a traumatic spinal cord injury in adult rats.
Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20100201
Title: Understanding the mode of action of ThDP in benzoylformate decarboxylase.
Journal: Biopolymers 20100101
Title: Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Journal: RNA (New York, N.Y.) 20100101
Title: Energy minimization methods applied to riboswitches: a perspective and challenges.
Journal: RNA biology 20100101
Title: The Thiamine diphosphate dependent Enzyme Engineering Database: a tool for the systematic analysis of sequence and structure relations.
Journal: BMC biochemistry 20100101
Title: Biomarkers for detecting thiamine deficiency--improving confidence and taking a comprehensive history are also important.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20100101
Title: [Existence of two different active sites on thiamine binding protein in plasma membranes of synaptosomes].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20100101
Title: Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
Journal: Bioscience, biotechnology, and biochemistry 20100101
Title: Analysis of riboswitch structure and function by an energy landscape framework.
Journal: Journal of molecular biology 20091106
Title: Structural and functional analysis of Vitamin K2 synthesis protein MenD.
Journal: Biochemical and biophysical research communications 20091030
Title: Simultaneous determination of thiamine and its phosphate esters by a liquid chromatographic method based on post-column photolysis and chemiluminescence detection.
Journal: Journal of pharmaceutical and biomedical analysis 20091015
Title: Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury.
Journal: Spinal cord 20091001
Title: Effects of vitamin B1 (thiamine) deficiency in lake trout (Salvelinus namaycush) alevins at hatching stage.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20091001
Title: Mechanism-guided library design and dual genetic selection of synthetic OFF riboswitches.
Journal: Chembiochem : a European journal of chemical biology 20090921
Title: Protein families reflect the metabolic diversity of organisms and provide support for functional prediction.
Journal: Physiological genomics 20090807
Title: Determination of thiamin diphosphate in whole blood samples by high-performance liquid chromatography--a method suitable for pediatric diagnostics.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090701
Title: Thiaminylated adenine nucleotides. Chemical synthesis, structural characterization and natural occurrence.
Journal: The FEBS journal 20090601
Title: Thiamin diphosphate in biological chemistry: applications in biocatalysis, coenzyme analogues as mechanistic probes and natural derivatives of thiamin.
Journal: The FEBS journal 20090601
Title: Thiamin diphosphate in biological chemistry: exploitation of diverse thiamin diphosphate-dependent enzymes for asymmetric chemoenzymatic synthesis.
Journal: The FEBS journal 20090601
Title: Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches.
Journal: The FEBS journal 20090601
Title: Thiamin diphosphate in biological chemistry: new aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors.
Journal: The FEBS journal 20090601
Title: Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate at different potassium ionic levels.
Journal: Bioscience, biotechnology, and biochemistry 20090501
Title: Reaction mechanisms of thiamin diphosphate enzymes.
Journal: The FEBS journal 20090501
Title: Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps.
Journal: The FEBS journal 20090501
Title: Reaction mechanisms of thiamin diphosphate enzymes: new insights into the role of a conserved glutamate residue.
Journal: The FEBS journal 20090501
Title: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions.
Journal: The FEBS journal 20090501
Title: Construction of a synthetic YdbK-dependent pyruvate:H2 pathway in Escherichia coli BL21(DE3).
Journal: Metabolic engineering 20090501
Title: Transketolase: observations in alcohol-related brain damage research.
Journal: The international journal of biochemistry & cell biology 20090401
Title: Enzymes that control the thiamine diphosphate pool in plant tissues. Properties of thiamine pyrophosphokinase and thiamine-(di)phosphate phosphatase purified from Zea mays seedlings.
Journal: Plant physiology and biochemistry : PPB 20090401
Title: Carboxylesterase activity, cDNA sequence, and gene expression in malathion susceptible and resistant strains of the cotton aphid, Aphis gossypii.
Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20090301
Title: Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
Journal: The FEBS journal 20090301
Title: New function of the amino group of thiamine diphosphate in thiamine catalysis.
Journal: Biochemistry. Biokhimiia 20090301
Title: Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
Journal: Biochemistry 20090210
Title: Artificial ribozyme switches containing natural riboswitch aptamer domains.
Journal: Angewandte Chemie (International ed. in English) 20090101
Title: Propioin synthesis using thiamine diphosphate-dependent enzymes.
Journal: Biotechnology progress 20090101
Title: Predicting riboswitch regulation on a genomic scale.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.
Journal: Structure (London, England : 1993) 20081210
Title: Chitosan-thiamine pyrophosphate as a novel carrier for siRNA delivery.
Journal: Pharmaceutical research 20081201
Title: Catalyzing separation of carbon dioxide in thiamin diphosphate-promoted decarboxylation.
Journal: The FEBS journal 20081201
Title: Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Journal: Acta crystallographica. Section D, Biological crystallography 20081101
Title: Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold.
Journal: Organic & biomolecular chemistry 20081007
Title: Switching the light on plant riboswitches.
Journal: Trends in plant science 20081001
Title: Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester.
Journal: Biochemistry 20080722
Title: Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch.
Journal: Journal of the American Chemical Society 20080702
Title: Riboswitch effectors as protein enzyme cofactors.
Journal: RNA (New York, N.Y.) 20080601
Title: Thiamin diphosphate catalysis: enzymic and nonenzymic covalent intermediates.
Journal: Chemical reviews 20080601
Title: Changes in ECG and enzyme activity in rat heart after myocardial infarction: effect of TPP and MnCl2.
Journal: Journal of physiology and biochemistry 20080601
Title: Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins.
Journal: Proteins 20080501
Title: A DFT study of solvation effects on the tautomeric equilibrium and catalytic ylide generation of thiamin models.
Journal: Journal of computational chemistry 20080501
Title: Rapid HPLC measurement of thiamine and its phosphate esters in whole blood.
Journal: Clinical chemistry 20080501
Title: Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects.
Journal: Biochemistry 20080325
Title: The evidence that the DNC (SLC25A19) is not the mitochondrial deoxyribonucleotide carrier.
Journal: Mitochondrion 20080301
Title: Amino acids allosterically regulate the thiamine diphosphate-dependent alpha-keto acid decarboxylase from Mycobacterium tuberculosis.
Journal: The Journal of biological chemistry 20080227
Title: Rational protein design of ThDP-dependent enzymes-engineering stereoselectivity.
Journal: Chembiochem : a European journal of chemical biology 20080215
Title: Structural similarities between thiamin-binding protein and thiaminase-I suggest a common ancestor.
Journal: Biochemistry 20080205
Title: Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides.
Journal: Biological chemistry 20080201
Title: Molecular basis of gene regulation by the THI-box riboswitch.
Journal: Molecular microbiology 20080201
Title: The mechanism of carrier-mediated transport of folates in BeWo cells: the involvement of heme carrier protein 1 in placental folate transport.
Journal: Bioscience, biotechnology, and biochemistry 20080201
Title: Pyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia.
Journal: Neuropediatrics 20080201
Title: Evolutionary analysis of the TPP-dependent enzyme family.
Journal: Journal of molecular evolution 20080101
Title: Thiamin phosphates in egg yolk granules and plasma of regular and embryonated eggs of hens and in five- and seven-day-old embryos.
Journal: Poultry science 20080101
Title: The genes and enzymes involved in the biosynthesis of thiamin and thiamin diphosphate in yeasts.
Journal: Cellular & molecular biology letters 20080101
Title: Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase.
Journal: BMC structural biology 20080101
Title: The preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments.
Journal: Nature protocols 20080101
Title: Effect of thiamine pyrophosphate on levels of serum lactate, maximum oxygen consumption and heart rate in athletes performing aerobic activity.
Journal: The Journal of international medical research 20080101
Title: [Thiamine metabolism disorders in the rat brain in experimental alcoholism and a possibility of their correction by vitamin E].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101
Title: Observation of an acryloyl-thiamin diphosphate adduct in the first step of clavulanic acid biosynthesis.
Journal: Journal of the American Chemical Society 20071226
Title: Thiamine diphosphate binds to intermediates in the assembly of adenovirus fiber knob trimers in Escherichia coli.
Journal: Protein science : a publication of the Protein Society 20071201
Title: Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction.
Journal: Acta crystallographica. Section D, Biological crystallography 20071201
Title: Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.
Journal: The Journal of biological chemistry 20071130
Title: Riboswitch-dependent gene regulation and its evolution in the plant kingdom.
Journal: Genes & development 20071115
Title: Reengineering a natural riboswitch by dual genetic selection.
Journal: Journal of the American Chemical Society 20071114
Title: Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs.
Journal: The Plant cell 20071101
Title: The structures of pyruvate oxidase from Aerococcus viridans with cofactors and with a reaction intermediate reveal the flexibility of the active-site tunnel for catalysis.
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20071101
Title: Reactions of fac-[Re(CO)3(H2O)3]+ with nucleoside diphosphates and thiamine diphosphate in aqueous solution investigated by multinuclear NMR spectroscopy.
Journal: Inorganic chemistry 20071029
Title: High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.
Journal: Diabetologia 20071001
Title: Elucidation of the chemistry of enzyme-bound thiamin diphosphate prior to substrate binding: defining internal equilibria among tautomeric and ionization states.
Journal: Biochemistry 20070918
Title: Structure of the ThDP-dependent enzyme benzaldehyde lyase refined to 1.65 A resolution.
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20070701
Title: Crystallographic snapshots of oxalyl-CoA decarboxylase give insights into catalysis by nonoxidative ThDP-dependent decarboxylases.
Journal: Structure (London, England : 1993) 20070701
Title: An activity, stability and selectivity comparison of propioin synthesis by thiamine diphosphate-dependent enzymes in a solid/gas bioreactor.
Journal: Chembiochem : a European journal of chemical biology 20070618
Title: [Thiamine and its derivates in cattle blood measured by HPLC in healthy animals, in patients suffering from CCN and in their cohorts].
Journal: DTW. Deutsche tierarztliche Wochenschrift 20070601
Title: Feasibility of gas/solid carboligation: conversion of benzaldehyde to benzoin using thiamine diphosphate-dependent enzymes.
Journal: Journal of biotechnology 20070510
Title: Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex.
Journal: Journal of molecular biology 20070504
Title: Cloning and characterization of a gene encoding phosphoketolase in a Lactobacillus paraplantarum isolated from Kimchi.
Journal: Journal of microbiology and biotechnology 20070501
Title: Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme.
Journal: Journal of the American Chemical Society 20070411
Title: Ligand binding and gene control characteristics of tandem riboswitches in Bacillus anthracis.
Journal: RNA (New York, N.Y.) 20070401
Title: Adenosine triphosphate and thiamine cross paths.
Journal: Nature chemical biology 20070401
Title: Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
Journal: Cellular and molecular life sciences : CMLS 20070401
Title: Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate.
Journal: Journal of the American Chemical Society 20070314
Title: Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics.
Journal: Chemical communications (Cambridge, England) 20070307
Title: The THI-box riboswitch, or how RNA binds thiamin pyrophosphate.
Journal: Structure (London, England : 1993) 20070301
Title: Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex.
Journal: Journal of molecular biology 20070209
Title: Which stage of the process of apotransketolase interaction with thiamine diphosphate is affected by the regulatory activity of the donor substrate?
Journal: IUBMB life 20070201
Title: RNA ligands that distinguish metabolite-induced conformations in the TPP riboswitch.
Journal: Angewandte Chemie (International ed. in English) 20070101
Title: Influence of donor substrate on kinetic parameters of thiamine diphosphate binding to transketolase.
Journal: Biochemistry. Biokhimiia 20070101
Title: Enzyme-catalyzed side reactions with molecular oxygen may contribute to cell signaling and neurodegenerative diseases.
Journal: Neurochemical research 20070101
Title: Presence of thiamine pyrophosphate in mammalian peroxisomes.
Journal: BMC biochemistry 20070101
Title: Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model.
Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070101
Title: [Characteristic metabolic disturbances in the rat tissues caused by long-term use of alcohol].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101
Title: Factors mediating activity, selectivity, and substrate specificity for the thiamin diphosphate-dependent enzymes benzaldehyde lyase and benzoylformate decarboxylase.
Journal: Chembiochem : a European journal of chemical biology 20061201
Title: Synthesis with good enantiomeric excess of both enantiomers of alpha-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases.
Journal: Bioorganic chemistry 20061201
Title: Theoretical model of interactions between ligand-binding sites in a dimeric protein and its application for the analysis of thiamine diphosphate binding to yeast transketolase.
Journal: Biophysical chemistry 20061120
Title: Function of a conserved loop of the beta-domain, not involved in thiamin diphosphate binding, in catalysis and substrate activation in yeast pyruvate decarboxylase.
Journal: Biochemistry 20061114
Title: Active-site changes in the pyruvate dehydrogenase multienzyme complex E1 apoenzyme component from Escherichia coli observed at 2.32 A resolution.
Journal: Acta crystallographica. Section D, Biological crystallography 20061101
Title: Structure of the thiazole biosynthetic enzyme THI1 from Arabidopsis thaliana.
Journal: The Journal of biological chemistry 20061013
Title: Thiamin nutrition and catalysis-induced instability of thiamin diphosphate.
Journal: The British journal of nutrition 20061001
Title: A Korean female patient with thiamine-responsive pyruvate dehydrogenase complex deficiency due to a novel point mutation (Y161C)in the PDHA1 gene.
Journal: Journal of Korean medical science 20061001
Title: Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch.
Journal: Chembiochem : a European journal of chemical biology 20060901
Title: Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition.
Journal: Structure (London, England : 1993) 20060901
Title: Thiamine models and perspectives on the mechanism of action of thiamine-dependent enzymes.
Journal: Chemical Society reviews 20060801
Title: Domain relationships in thiamine diphosphate-dependent enzymes.
Journal: Accounts of chemical research 20060801
Title: Flipping off the riboswitch: RNA structures that control gene expression.
Journal: ACS chemical biology 20060721
Title: Thiamine pyrophosphate: an essential cofactor for the alpha-oxidation in mammals--implications for thiamine deficiencies?
Journal: Cellular and molecular life sciences : CMLS 20060701
Title: Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch.
Journal: Nature 20060629
Title: Structural biology: RNA switches function.
Journal: Nature 20060629
Title: Electronic and nuclear magnetic resonance spectroscopic features of the 1',4'-iminopyrimidine tautomeric form of thiamin diphosphate, a novel intermediate on enzymes requiring this coenzyme.
Journal: Biochemistry 20060620
Title: EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.
Journal: Biochemistry 20060613
Title: Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis.
Journal: Journal of the American Chemical Society 20060607
Title: The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Journal: Nature chemical biology 20060601
Title: Snapshots of three intermediates at the active site of pyruvate oxidase.
Journal: Nature chemical biology 20060601
Title: Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand.
Journal: Science (New York, N.Y.) 20060526
Title: The electrochemical investigation of the catalytic power of pyruvate decarboxylase and its coenzyme.
Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20060501
Title: Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate.
Journal: Structure (London, England : 1993) 20060201
Title: A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase.
Journal: Structure (London, England : 1993) 20060201
Title: Structural studies of the purine and SAM binding riboswitches.
Journal: Cold Spring Harbor symposia on quantitative biology 20060101
Title: [Liquid chromatographic determination of free thiamine and its esters in whole blood].
Journal: Dakar medical 20060101
Title: Structural basis for activation of the thiamin diphosphate-dependent enzyme oxalyl-CoA decarboxylase by adenosine diphosphate.
Journal: The Journal of biological chemistry 20051216
Title: Inclusion of thiamine diphosphate and S-adenosylmethionine at their chemically active sites.
Journal: The Journal of organic chemistry 20051209
Title: The relationship between plasma and red cell B-vitamin concentrations in critically-ill patients.
Journal: Clinical nutrition (Edinburgh, Scotland) 20051201
Title: Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens.
Journal: The FEBS journal 20051201
Title: Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine.
Journal: Chemistry & biology 20051201
Title: Cofactor activation and substrate binding in pyruvate decarboxylase. Insights into the reaction mechanism from molecular dynamics simulations.
Journal: Biochemistry 20051115
Title: Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum. Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair.
Journal: Biochemistry 20051011
Title: Genetic regulation mediated by thiamin pyrophosphate-binding motif in Saccharomyces cerevisiae.
Journal: Molecular microbiology 20051001
Title: Modification of thiamine pyrophosphate dependent enzyme activity by oxythiamine in Saccharomyces cerevisiae cells.
Journal: Canadian journal of microbiology 20051001
Title: Multiple modes of active center communication in thiamin diphosphate-dependent enzymes.
Journal: Accounts of chemical research 20050901
Title: Topological analysis of the electron density in model azolium systems for thiamin structure-function: sulfur is the electron sink and positively polarized carbanions act as nucleophiles.
Journal: The journal of physical chemistry. A 20050825
Title: The analysis of thiamin and its derivatives in whole blood samples under high pH conditions of the mobile phase.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805
Title: Studies on thiamine diphosphate-dependent enzymes.
Journal: Biochemical Society transactions 20050801
Title: The potential role of thiamine (vitamin B1) in diabetic complications.
Journal: Current diabetes reviews 20050801
Title: Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida.
Journal: Protein engineering, design & selection : PEDS 20050701
Title: Binding of the coenzyme and formation of the transketolase active center.
Journal: IUBMB life 20050701
Title: Effect of transketolase substrates on holoenzyme reconstitution and stability.
Journal: Biochemistry. Biokhimiia 20050701
Title: Kinetic control of thiamin diphosphate activation in enzymes studied by proton-nitrogen correlated NMR spectroscopy.
Journal: Biochemistry 20050621
Title: Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity.
Journal: The Journal of biological chemistry 20050603
Title: Experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.
Journal: Bioorganic chemistry 20050601
Title: Roles of Mg2+ in TPP-dependent riboswitch.
Journal: FEBS letters 20050509
Title: How an enzyme answers multiple-choice questions.
Journal: Trends in biochemical sciences 20050501
Title: Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.
Journal: Biochemistry 20050426
Title: Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.
Journal: The Journal of biological chemistry 20050318
Title: Biosynthesis of hydroxymethylpyrimidine pyrophosphate in Saccharomyces cerevisiae.
Journal: Current genetics 20050301
Title: Determination of thiamine and its phosphate esters in rat tissues analyzed as thiochromes on a RP-amide C16 column.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225
Title: Evidence for dramatic acceleration of a C-H bond ionization rate in thiamin diphosphate enzymes by the protein environment.
Journal: Biochemistry 20050222
Title: Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.
Journal: Biochemistry 20050222
Title: Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula.
Journal: Pediatrics 20050201
Title: Suicide inhibition of acetohydroxyacid synthase by hydroxypyruvate.
Journal: Journal of enzyme inhibition and medicinal chemistry 20050201
Title: Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.
Journal: Malaria journal 20050101
Title: Adult hypophosphatasia and a low level of red blood cell thiamine pyrophosphate.
Journal: Annals of nutrition & metabolism 20050101
Title: Interaction of thiamin diphosphate with phosphorylated and dephosphorylated mammalian pyruvate dehydrogenase complex.
Journal: Biological chemistry 20050101
Title: [Functional activity of blood and liver cells under formaldehyde intoxication via inhalation].
Journal: Biomeditsinskaia khimiia 20050101
Title: Erythrocyte thiamine (Th) esters: a major factor of the alcohol withdrawal syndrome or a candidate marker for alcoholism itself?
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Title: Assay values for thiamine or thiamine phosphate esters in whole blood do not depend on the anticoagulant used.
Journal: Journal of clinical laboratory analysis 20050101
Title: C2-alpha-lactylthiamin diphosphate is an intermediate on the pathway of thiamin diphosphate-dependent pyruvate decarboxylation. Evidence on enzymes and models.
Journal: The Journal of biological chemistry 20041224
Title: [Erythrocyte transketolase].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20041201
Title: Suicidal dephosphorylation of thiamine pyrophosphate coupled with pyruvate dehydrogenase complex.
Journal: The Italian journal of biochemistry 20041201
Title: Effects of deletions at the C-terminus of tobacco acetohydroxyacid synthase on the enzyme activity and cofactor binding.
Journal: The Biochemical journal 20041115
Title: Donor substrate regulation of transketolase.
Journal: European journal of biochemistry 20041101
Title: Biochemistry. How active sites communicate in thiamine enzymes.
Journal: Science (New York, N.Y.) 20041029
Title: A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
Journal: Science (New York, N.Y.) 20041029
Title: The relationship between plasma and red cell concentrations of vitamins thiamine diphosphate, flavin adenine dinucleotide and pyridoxal 5-phosphate following elective knee arthroplasty.
Journal: Clinical nutrition (Edinburgh, Scotland) 20041001
Title: Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans.
Journal: Genetics 20041001
Title: Optical characteristics of thiamine in model systems and in holoenzyme.
Journal: Biochemistry. Biokhimiia 20040901
Title: The molecular origin of the thiamine diphosphate-induced spectral bands of ThDP-dependent enzymes.
Journal: Proteins 20040801
Title: A new perspective on thiamine catalysis.
Journal: Current opinion in biotechnology 20040801
Title: Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a 'nonredox' flavoenzyme.
Journal: Biochemistry 20040713
Title: Obese individuals as thiamin storers.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040701
Title: Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate.
Journal: Organic & biomolecular chemistry 20040621
Title: Kinetic study of the H103A mutant yeast transketolase.
Journal: FEBS letters 20040604
Title: The role of cysteine 160 in thiamine diphosphate binding of the Calvin-Benson-Bassham cycle transketolase of Rhodobacter sphaeroides.
Journal: Archives of biochemistry and biophysics 20040601
Title: Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
Journal: Biochemistry 20040601
Title: Structural and biochemical basis for novel mutations in homozygous Israeli maple syrup urine disease patients: a proposed mechanism for the thiamin-responsive phenotype.
Journal: The Journal of biological chemistry 20040423
Title: The reaction of dimethyltin(IV) dichloride with thiamine diphosphate (H2TDP): synthesis and structure of [SnMe2(HTDP)(H2O)]Cl.H2O, and possibility of a hitherto unsuspected role of the metal cofactor in the mechanism of vitamin-B1-dependent enzymes.
Journal: Inorganic chemistry 20040322
Title: Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate.
Journal: Biochemistry 20040309
Title: Thiamine binding and metabolism in germinating seeds of selected cereals and legumes.
Journal: Plant physiology and biochemistry : PPB 20040301
Title: The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate.
Journal: The Journal of biological chemistry 20040116
Title: The active site and mechanism of action of recombinant acetohydroxy acid synthase from tobacco.
Journal: FEBS letters 20031204
Title: Effect of thiamine on 3H-MPP+ uptake by Caco-2 cells.
Journal: Pharmacological research 20031201
Title: Three thiamine analogues differently alter thiamine transport and metabolism in nervous tissue: an in vivo kinetic study using rats.
Journal: Metabolic brain disease 20031201
Title: Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase.
Journal: Biochemistry 20031125
Title: An efficient enzymatic synthesis of thiamin pyrophosphate.
Journal: Bioorganic & medicinal chemistry letters 20031117
Title: Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.
Journal: Journal of the American Chemical Society 20031022
Title: Genetic control by metabolite-binding riboswitches.
Journal: Chembiochem : a European journal of chemical biology 20031006
Title: Structure and properties of an engineered transketolase from maize.
Journal: Plant physiology 20030801
Title: NMR analysis of covalent intermediates in thiamin diphosphate enzymes.
Journal: Biochemistry 20030708
Title: Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase.
Journal: The Journal of biological chemistry 20030606
Title: Metabolite-binding RNA domains are present in the genes of eukaryotes.
Journal: RNA (New York, N.Y.) 20030601
Title: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid.
Journal: European journal of biochemistry 20030501
Title: Studies on structure-function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway.
Journal: European journal of biochemistry 20030501
Title: Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions.
Journal: Natural product reports 20030401
Title: Pyruvate:NADP+ oxidoreductase is stabilized by its cofactor, thiamin pyrophosphate, in mitochondria of Euglena gracilis.
Journal: Archives of biochemistry and biophysics 20030315
Title: Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase.
Journal: Biochemistry 20030225
Title: The coenzyme thiamine pyrophosphate inhibits the self-splicing of the group I intron.
Journal: The international journal of biochemistry & cell biology 20030201
Title: Effect of intravenous infusions of thiamine on the disposition kinetics of thiamine and its pyrophosphate.
Journal: Journal of clinical pharmacy and therapeutics 20030201
Title: Induced absorption band of holotransketolase and its interpretation.
Journal: Biochemistry. Biokhimiia 20030201
Title: Biochemical characterization of two mutants of human pyruvate dehydrogenase, F205L and T231A of the E1alpha subunit.
Journal: Journal of inherited metabolic disease 20030101
Title: Thiamine pyrophosphate: an essential cofactor in the mammalian metabolism of 3-methyl-branched fatty acids--implications for thiamine deficiencies?
Journal: Advances in experimental medicine and biology 20030101
Title: Thiamin-diphosphate-dependent enzymes: new aspects of asymmetric C-C bond formation.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20021202
Title: A (ribo) switch in the paradigms of genetic regulation.
Journal: Nature structural biology 20021201
Title: Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate.
Journal: The EMBO journal 20021101
Title: Molecular biology: RNA gets a grip on translation.
Journal: Nature 20021031
Title: Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression.
Journal: Nature 20021031
Title: A novel Y243S mutation in the pyruvate dehydrogenase El alpha gene subunit: correlation with thiamine pyrophosphate interaction.
Journal: Journal of inherited metabolic disease 20020801
Title: Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020701
Title: Spectroscopic evidence for participation of the 1',4'-imino tautomer of thiamin diphosphate in catalysis by yeast pyruvate decarboxylase.
Journal: Bioorganic chemistry 20020601
Title: The origin of the absorption band induced through the interaction between apotransketolase and thiamin diphosphate.
Journal: Biochemical and biophysical research communications 20020531
Title: Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution.
Journal: Biochemistry 20020423
Title: [Drug therapy for mitochondrial diseases].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020401
Title: Growth-phase dependent expression of the mevalonate pathway in a terpenoid antibiotic-producing Streptomyces strain.
Journal: Bioscience, biotechnology, and biochemistry 20020401
Title: Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.
Journal: Journal of molecular biology 20020322
Title: Practical tethering of vitamin B1 on a silica surface via its phosphate group and evaluation of its activity.
Journal: Chemical communications (Cambridge, England) 20020307
Title: Evaluation of oxidative stress indices during treatment in pregnant women with intrauterine growth retardation.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20020301
Title: Thiamine deficiency in hepatitis C virus and alcohol-related liver diseases.
Journal: Digestive diseases and sciences 20020301
Title: Simultaneous detection of thiamine and its phosphate esters from microalgae by HPLC.
Journal: Biochemical and biophysical research communications 20020222
Title: Characterization of a missense mutation at histidine-44 in a pyruvate dehydrogenase-deficient patient.
Journal: Biochimica et biophysica acta 20020102
Title: Reduced serum concentrations of riboflavine and ascorbic acid, and blood thiamine pyrophosphate and pyridoxal-5-phosphate in geriatric patients with and without pressure sores.
Journal: The journal of nutrition, health & aging 20020101
Title: Mitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate.
Journal: BMC biochemistry 20020101
Title: [Relative reactivity of thiamine monophosphate and thiamine diphosphate upon interaction with alkaline phosphatase].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101
Title: Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases.
Journal: Experimental & molecular medicine 20011231
Title: Enzymology. Coenzymes and radicals.
Journal: Science (New York, N.Y.) 20011221
Title: Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase.
Journal: Science (New York, N.Y.) 20011221
Title: Cooperation of divalent ions and thiamin diphosphate in regulation of the function of pig heart pyruvate dehydrogenase complex.
Journal: Journal of nutritional science and vitaminology 20011201
Title: Binding and activation of thiamin diphosphate in acetohydroxyacid synthase.
Journal: Biochemistry 20011002
Title: Functional flexibility of the transketolase molecule.
Journal: Biochemistry. Biokhimiia 20011001
Title: The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite.
Journal: Bioorganic & medicinal chemistry letters 20010903
Title: Thiamin auxotrophy in yeast through altered cofactor dependence of the enzyme acetohydroxyacid synthase.
Journal: Microbiology (Reading, England) 20010901
Title: Complexation of Cu(2+) by HETPP and the pentapeptide Asp-Asp-Asn-Lys-Ile: a structural model of the active site of thiamin-dependent enzymes in solution.
Journal: Inorganic chemistry 20010827
Title: Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites.
Journal: The Biochemical journal 20010815
Title: Cleaving of ketosubstrates by transketolase and the nature of the products formed.
Journal: Biochemistry. Biokhimiia 20010801
Title: Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.
Journal: Biochemistry 20010626
Title: Examination of donor substrate conversion in yeast transketolase.
Journal: The Journal of biological chemistry 20010511
Title: The use of thiamine and thiamine antagonists to investigate the etiology of early mortality syndrome in lake trout (Salvelinus namaycush).
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20010501
Title: Molecular mechanisms of thiamine utilization.
Journal: Current molecular medicine 20010501
Title: Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.
Journal: Archives of biochemistry and biophysics 20010215
Title: Inhibitors of advanced glycation end product-associated protein cross-linking.
Journal: Biochimica et biophysica acta 20010214
Title: Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.
Journal: Biochemistry 20010213
Title: Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells.
Journal: The Journal of biological chemistry 20010112
Title: Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy.
Journal: Neurology 19861101
Title: Protection against misonidazole-induced neuropathy in rats: a biochemical assessment.
Journal: Toxicology letters 19830601
Title: The pyruvate-dehydrogenase complex from Azotobacter vinelandii. 2. Regulation of the activity.
Journal: European journal of biochemistry 19751115