Title: Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists.
Journal: Journal of medicinal chemistry 20131114
Title: Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway.
Journal: The Journal of biological chemistry 20130510
Title: Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.
Journal: Anesthesiology 20130501
Title: The CB2-preferring agonist JWH015 also potently and efficaciously activates CB1 in autaptic hippocampal neurons.
Journal: Pharmacological research 20121101
Title: Cannabinoid CB(2) receptor attenuates morphine-induced inflammatory responses in activated microglial cells.
Journal: British journal of pharmacology 20120801
Title: The inhibition of the nitric oxide-cGMP-PKG-JNK signaling pathway avoids the development of tolerance to the local antiallodynic effects produced by morphine during neuropathic pain.
Journal: European journal of pharmacology 20120615
Title: Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents.
Journal: Bioorganic & medicinal chemistry 20120315
Title: Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.
Journal: Neurotoxicology 20120101
Title: Intrathecal administration of the cannabinoid 2 receptor agonist JWH015 can attenuate cancer pain and decrease mRNA expression of the 2B subunit of N-methyl-D-aspartic acid.
Journal: Anesthesia and analgesia 20110801
Title: Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy.
Journal: Cell death and differentiation 20110701
Title: Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2.
Journal: European journal of medicinal chemistry 20110201
Title: Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.
Journal: PloS one 20110101
Title: Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases.
Journal: PloS one 20110101
Title: The antinociceptive effects of JWH-015 in chronic inflammatory pain are produced by nitric oxide-cGMP-PKG-KATP pathway activation mediated by opioids.
Journal: PloS one 20110101
Title: Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?
Journal: Molecular pharmaceutics 20101206
Title: Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure.
Journal: Neurochemical research 20100901
Title: Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain.
Journal: Journal of neurochemistry 20100401
Title: Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity.
Journal: Journal of medicinal chemistry 20100114
Title: Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2.
Journal: British journal of cancer 20090915
Title: Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists.
Journal: Journal of medicinal chemistry 20090625
Title: Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors.
Journal: European journal of medicinal chemistry 20090601
Title: Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5.
Journal: British journal of pharmacology 20080801
Title: TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080611
Title: Selective CB2 up-regulation in women affected by endometrial inflammation.
Journal: Journal of cellular and molecular medicine 20080401
Title: Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
Journal: Journal of medicinal chemistry 20080327
Title: Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor.
Journal: Current topics in medicinal chemistry 20080101
Title: Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans.
Journal: The pharmacogenomics journal 20071201
Title: Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.
Journal: Journal of molecular medicine (Berlin, Germany) 20071201
Title: The orphan receptor GPR55 is a novel cannabinoid receptor.
Journal: British journal of pharmacology 20071201
Title: Endothelial CB1-receptors limit infarct size through NO formation in rat isolated hearts.
Journal: Life sciences 20071013
Title: Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations.
Journal: Pharmacological research 20070901
Title: Evidence for a modulatory role of cannabinoids on the excitatory NANC neurotransmission in mouse colon.
Journal: Pharmacological research 20070801
Title: Sch35966 is a potent, selective agonist at the peripheral cannabinoid receptor (CB2) in rodents and primates.
Journal: British journal of pharmacology 20070801
Title: Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids.
Journal: Journal of leukocyte biology 20070101
Title: Impact of cannabinoid receptor ligands on behavioural sensitization to antiaggressive methamphetamine effects in the model of mouse agonistic behaviour.
Journal: Neuro endocrinology letters 20061201
Title: Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS.
Journal: Analytical and bioanalytical chemistry 20061101
Title: Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20061001
Title: Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3K-dependent mechanisms: role of NF-kappaB and p53.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20060901
Title: Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes.
Journal: Molecular immunology 20060701
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Cannabinoid receptor type 2 agonists induce transcription of the mu-opioid receptor gene in Jurkat T cells.
Journal: Molecular pharmacology 20060401
Title: Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice.
Journal: Neuro endocrinology letters 20060101
Title: Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB2 receptor.
Journal: Bioorganic & medicinal chemistry letters 20050815
Title: CB2 receptor ligands.
Journal: Mini reviews in medicinal chemistry 20050701
Title: Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells.
Journal: The Biochemical journal 20050601
Title: Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors.
Journal: European journal of pharmacology 20041128
Title: Characterization of cannabinoid modulation of sensory neurotransmission in the rat isolated mesenteric arterial bed.
Journal: The Journal of pharmacology and experimental therapeutics 20041001
Title: Effects of cannabinoids on non-adrenergic non-cholinergic-mediated relaxation in guinea-pig trachea.
Journal: European journal of pharmacology 20030815
Title: Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.
Journal: British journal of pharmacology 20030601
Title: Pharmacological characterisation of cannabinoid receptors inhibiting interleukin 2 release from human peripheral blood mononuclear cells.
Journal: European journal of pharmacology 20030319
Title: R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors.
Journal: European journal of pharmacology 20030110
Title: Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids.
Journal: European journal of pharmacology 20030101
Title: Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20000301
Title: Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
Journal: The Journal of pharmacology and experimental therapeutics 19970601
