Home Fluorides 158848-32-9
158848-32-9,MFCD05665140
Catalog No.:AA00AKNG

158848-32-9 | 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
≥98%
in stock  
$262.00   $183.00
- +
10mg
≥98%
in stock  
$368.00   $257.00
- +
25mg
99%
in stock  
$883.00   $618.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AKNG
Chemical Name:
5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE
CAS Number:
158848-32-9
Molecular Formula:
C23H27FN2O2S
Molecular Weight:
414.5361
MDL Number:
MFCD05665140
SMILES:
COC1(CCN(CC1)CCc1c[nH]c2c1cc(F)cc2)C[S@@](=O)c1ccccc1
Properties
Computed Properties
 
Complexity:
549  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
3.4  

Literature

Title: Role of tachykinin and neurokinin receptors in the regulation of ovine omasal contractions.

Journal: Regulatory peptides 20120110

Title: Involvement of substance P in peripheral neuropathy induced by paclitaxel but not oxaliplatin.

Journal: The Journal of pharmacology and experimental therapeutics 20110401

Title: Delay of cutaneous wound closure by morphine via local blockade of peripheral tachykinin release.

Journal: Biochemical pharmacology 20070901

Title: Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.

Journal: Pharmacology 20020501

Title: New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists.

Journal: Journal of medicinal chemistry 19950915

Title: GR159897, a potent non-peptide antagonist at tachykinin NK2 receptors.

Journal: European journal of pharmacology 19950116

Title: Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor.

Journal: Biochemical and biophysical research communications 19930331

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Tags:158848-32-9 Molecular Formula|158848-32-9 MDL|158848-32-9 SMILES|158848-32-9 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE