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Home Other Building Blocks 15985-39-4
15985-39-4,MFCD00002621
Catalog No.:AA001RDS

15985-39-4 | L-Methionine sulfoximine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$45.00   $32.00
- +
250mg
98%
in stock  
$64.00   $45.00
- +
1g
98%
in stock  
$253.00   $178.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001RDS
Chemical Name:
L-Methionine sulfoximine
CAS Number:
15985-39-4
Molecular Formula:
C5H12N2O3S
Molecular Weight:
180.2254
MDL Number:
MFCD00002621
SMILES:
OC(=O)[C@H](CCS(=O)(=N)C)N
Properties
Properties
 
BP:
352.2°C at 760 mmHg  
Form:
Solid  
MP:
>210 °C (dec.)(lit.)  
Refractive Index:
1.6430 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
244  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-1.8  

Downstream Synthesis Route

[1]Murakoshi;Sekine;Maeshima;Ikegami;Yoshinaga;Fujii;Okonogi[ChemicalandPharmaceuticalBulletin,1993,vol.41,#2,p.388-390]

15985-39-4    60-24-2    643-79-8   
C15H20N2O4S2 

[1]Locationinpatent:experimentalpartCarmo-Silva,AnaE.;Keys,AlfredJ.;Beale,MichaelH.;Ward,JaneL.;Baker,JohnM.;Hawkins,NathanielD.;Arrabaca,MariaCeleste;Parry,MartinA.J.[Phytochemistry,2009,vol.70,#5,p.664-671]

tert-butyl(2S)-2-(tert-butoxycarbonyl)amino-4-N-(tert-butoxycarbonyl)-S-methylsulfonimidoyl-butanoate 
  15985-39-4 

[1]Zenzola,Marina;Doran,Robert;Luisi,Renzo;Bull,JamesA.[JournalofOrganicChemistry,2015,vol.80,#12,p.6391-6399]

[2]Bull,JamesA.;Degennaro,Leonardo;Luisi,Renzo[Synlett,2017,vol.28,#19,p.2525-2538]

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery.

Journal: Bioorganic & medicinal chemistry 20080515

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

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SDS
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