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1651-29-2,MFCD02183557
Catalog No.:AA001V6Z

1651-29-2 | 6-Chloro-2-fluoropurine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$7.00   $5.00
- +
5g
98%
in stock  
$23.00   $16.00
- +
10g
98%
in stock  
$36.00   $25.00
- +
25g
98%
in stock  
$89.00   $62.00
- +
100g
98%
in stock  
$351.00   $246.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001V6Z
Chemical Name:
6-Chloro-2-fluoropurine
CAS Number:
1651-29-2
Molecular Formula:
C5H2ClFN4
Molecular Weight:
172.5476
MDL Number:
MFCD02183557
SMILES:
Fc1nc(Cl)c2c(n1)[nH]cn2
NSC Number:
37363
Properties
Computed Properties
 
Complexity:
157  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
XLogP3:
1.2  

Upstream Synthesis Route

[1]JournalofOrganicChemistry,1992,vol.57,#14,p.3887-3894

[2]JournalofMedicinalChemistry,2017,vol.60,#5,p.1746-1767

[3]TetrahedronLetters,1997,vol.38,#7,p.1161-1164

[4]Patent:US2002/68721,2002,A1,

[5]Patent:WO2004/16612,2004,A2,.Locationinpatent:Page54

[6]Patent:WO2004/16613,2004,A2,.Locationinpatent:Page52

[7]BioorganicandMedicinalChemistryLetters,2009,vol.19,#1,p.242-246

[8]Patent:US2008/119467,2008,A1,.Locationinpatent:Page/Pagecolumn9

[1]Patent:CN105130989,2017,B,.Locationinpatent:Paragraph0019;0027;0028

Downstream Synthesis Route

[1]JournalofOrganicChemistry,1992,vol.57,p.3887-3894

[2]JournalofMedicinalChemistry,2017,vol.60,p.1746-1767

[3]TetrahedronLetters,1997,vol.38,p.1161-1164

[4]Patent:US2002/68721,2002,A1

[5]Patent:WO2004/16612,2004,A2.Locationinpatent:Page54

[6]Patent:WO2004/16613,2004,A2.Locationinpatent:Page52

[7]BioorganicandMedicinalChemistryLetters,2009,vol.19,p.242-246

[8]Patent:US2008/119467,2008,A1.Locationinpatent:Page/Pagecolumn9

65481-69-8    1651-29-2   
(1S,2R,4R)-Bicyclo2.2.1hept-2-yl-(2-fluoro-9H-purin-6-yl)-amine 

[1]Perreira,Melissa;Jiang,Jian-Kang;Klutz,AthenaM.;Gao,Zhan-Guo;Shainberg,Asher;Lu,Changrui;Thomas,CraigJ.;Jacobson,KennethA.[JournalofMedicinalChemistry,2005,vol.48,#15,p.4910-4918]

[1]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED-US2002/68721,2002,A1

[2]CurrentPatentAssignee:PFIZERINC-US2015/141402,2015,A1Locationinpatent:Paragraph0604;0605

[3]Locationinpatent:experimentalpartYenugonda,VenkataMahidhar;Deb,TusharB.;Grindrod,ScottC.;Dakshanamurthy,Sivanesan;Yang,Yonghong;Paige,Mikell;Brown,MiltonL.[BioorganicandMedicinalChemistry,2011,vol.19,#8,p.2714-2725]

[1]Patent:WO2006/136005,2006,A1.Locationinpatent:Page/Pagecolumn23-25

[1]Patent:WO2008/122767,2008,A2.Locationinpatent:Page/Pagecolumn69-70

Literature

Title: Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.

Journal: Nature chemical biology 20080601

Title: 'Reversine' and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20050728

Title: Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase.

Journal: Chemistry & biology 20021101

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