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16691-43-3,MFCD00005231
Catalog No.:AA0033IF

16691-43-3 | 3-Amino-1H-1,2,4-triazole-5-thiol

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5g
95%
in stock  
$6.00   $4.00
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10g
95%
in stock  
$7.00   $5.00
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25g
95%
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$9.00   $6.00
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500g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0033IF
Chemical Name:
3-Amino-1H-1,2,4-triazole-5-thiol
CAS Number:
16691-43-3
Molecular Formula:
C2H4N4S
Molecular Weight:
116.1450
MDL Number:
MFCD00005231
SMILES:
Nc1n[nH]c(n1)S
Properties
Properties
 
BP:
201.2°C at 760 mmHg  
Form:
Solid  
MP:
>300 °C(lit.)  
Refractive Index:
1.5605 (estimate)  
Solubility:
water: soluble25mg/mL, clear, faintly yellow to yellow  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
128  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
3  
XLogP3:
-0.8  

Upstream Synthesis Route

[1]AsianJournalofChemistry,2011,vol.23,#2,p.602-608

[2]EuropeanJournalofMedicinalChemistry,2013,vol.64,p.54-61

[1]JournalofHeterocyclicChemistry,1989,vol.26,p.355-360

Downstream Synthesis Route

[1]ChemischeBerichte,1922,vol.55,p.13

[2]JournaloftheIndianInstituteofScience,SectionA,1938,vol.21,p.51    ChemischesZentralblatt,1938,vol.109,p.2933

[1]EuropeanJournalofMedicinalChemistry,1981,vol.16,p.233-239

[1]Kuenstlinger,M.;Breitmaier,E.[Synthesis,1983,#1,p.44-47]

[1]White,AndrewD.;Creswell,MarkW.;Chucholowski,AlexanderW.;Blankley,C.John;Wilson,MichaelW.;Bousley,RichardF.;Essenburg,ArnoldD.;Hamelehle,KatherineL.;Krause,BrianR.;Stanfield,RichardL.;Dominick,MarkA.;Neub,Martin[JournalofMedicinalChemistry,1996,vol.39,#22,p.4382-4395]

[1]Chen,Qiong;Zhu,Xiao-Lei;Jiang,Li-Li;Liu,Zu-Ming;Yang,Guang-Fu[EuropeanJournalofMedicinalChemistry,2008,vol.43,#3,p.595-603]

Literature

Title: Highly sensitive determination of uric acid in the presence of major interferents using a conducting polymer film modified electrode.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20121201

Title: Chemical stabilization of gold coated by silver core-shell nanoparticles via electron transfer.

Journal: Nanotechnology 20120622

Title: FT-IR, FT-Raman, ab initio and DFT studies, HOMO-LUMO and NBO analysis of 3-amino-5-mercapto-1,2,4-triazole.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

Title: Selective determination of inosine in the presence of uric acid and hypoxanthine using modified electrode.

Journal: Analytical biochemistry 20120201

Title: Electrochemical sensor for neurotransmitters at physiological pH using a heterocyclic conducting polymer modified electrode.

Journal: The Analyst 20120107

Title: Occupational asthma: new low-molecular-weight causal agents, 2000-2010.

Journal: Journal of allergy 20120101

Title: Au-nanoclusters incorporated 3-amino-5-mercapto-1,2,4-triazole film modified electrode for the simultaneous determination of ascorbic acid, dopamine, uric acid and nitrite.

Journal: Biosensors & bioelectronics 20111215

Title: Allergic Potential and Immunotoxicity Induced by Topical Application of 1-Chloro-4-(Trifluoromethyl)Benzene (PCBTF) in a Murine Model.

Journal: Journal of allergy 20110101

Title: The LLNA: A Brief Review of Recent Advances and Limitations.

Journal: Journal of allergy 20110101

Title: Inhalation of ortho-phthalaldehyde vapor causes respiratory sensitization in mice.

Journal: Journal of allergy 20110101

Title: Oxidatively generated DNA damage induced by 3-amino-5-mercapto-1,2,4-triazole, a metabolite of carcinogenic amitrole.

Journal: Mutation research 20101210

Title: Raman characterization of monolayers formed from mixtures of sodium 2-mercaptoethanesulfonate and various aromatic mercapto-derivative bases.

Journal: The journal of physical chemistry. B 20100422

Title: Comparison of ethanol and acetaldehyde toxicity in rat astrocytes in primary culture.

Journal: Arhiv za higijenu rada i toksikologiju 20090901

Title: Synthesis and spectral studies of organotin(IV) 4-amino-3-alkyl-1,2,4-triazole-5-thionates: in vitro antimicrobial activity.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080901

Title: Corrosion of copper in aerated acidic pickling solutions and its inhibition by 3-amino-1,2,4-triazole-5-thiol.

Journal: Journal of colloid and interface science 20070201

Title: Cerebellar lesions in tuberous sclerosis complex: neurobehavioral and neuroimaging correlates.

Journal: Journal of child neurology 20061001

Title: Norepinephrine protects cortical neurons against microglial-induced cell death.

Journal: Journal of neuroscience research 20050801

Title: Potential role of inducible nitric oxide synthase in the sleep-wake states occurrence in old rats.

Journal: Neuroscience 20050101

Title: REM sleep control during aging in SAM mice: a role for inducible nitric oxide synthase.

Journal: Neurobiology of aging 20050101

Title: New-onset asthma associated with exposure to 3-amino-5-mercapto-1,2,4-triazole.

Journal: Journal of occupational and environmental medicine 20041201

Title: Determination of 3-amino-5-mercapto-1,2,4-triazole in serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305

Title: Dermal exposure to 3-amino-5-mercapto-1,2,4-triazole (AMT) induces sensitization and airway hyperreactivity in BALB/c mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030901

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