Home Iodos 167817-55-2
167817-55-2,MFCD01860665
Catalog No.:AA001XJ6

167817-55-2 | 2-Iodo-l-phenylalanine

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250mg
95%
in stock  
$170.00   $119.00
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500mg
97%
in stock  
$310.00   $217.00
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1g
≥ 98% (HPLC)
in stock  
$391.00   $274.00
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5g
97%
in stock  
$1,538.00   $1,077.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001XJ6
Chemical Name:
2-Iodo-l-phenylalanine
CAS Number:
167817-55-2
Molecular Formula:
C9H10INO2
Molecular Weight:
291.0857
MDL Number:
MFCD01860665
SMILES:
OC(=O)[C@H](Cc1ccccc1I)N
Properties
Computed Properties
 
Complexity:
187  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-0.9  

Downstream Synthesis Route

[1]VanDerPoorten,Olivier;VanDenHauwe,Robin;Eiselt,Emilie;Betti,Cecilia;Guillemyn,Karel;Chung,NgaN.;Hallé,François;Bihel,Frédéric;Schiller,PeterW.;Tourwé,Dirk;Sarret,Philippe;Gendron,Louis;Ballet,Steven[ACSMedicinalChemistryLetters,2017,vol.8,#11,p.1177-1182]

[1]VanDerPoorten,Olivier;VanDenHauwe,Robin;Eiselt,Emilie;Betti,Cecilia;Guillemyn,Karel;Chung,NgaN.;Hallé,François;Bihel,Frédéric;Schiller,PeterW.;Tourwé,Dirk;Sarret,Philippe;Gendron,Louis;Ballet,Steven[ACSMedicinalChemistryLetters,2017,vol.8,#11,p.1177-1182]

[1]VanDerPoorten,Olivier;VanDenHauwe,Robin;Eiselt,Emilie;Betti,Cecilia;Guillemyn,Karel;Chung,NgaN.;Hallé,François;Bihel,Frédéric;Schiller,PeterW.;Tourwé,Dirk;Sarret,Philippe;Gendron,Louis;Ballet,Steven[ACSMedicinalChemistryLetters,2017,vol.8,#11,p.1177-1182]

[1]VanDerPoorten,Olivier;VanDenHauwe,Robin;Eiselt,Emilie;Betti,Cecilia;Guillemyn,Karel;Chung,NgaN.;Hallé,François;Bihel,Frédéric;Schiller,PeterW.;Tourwé,Dirk;Sarret,Philippe;Gendron,Louis;Ballet,Steven[ACSMedicinalChemistryLetters,2017,vol.8,#11,p.1177-1182]

[1]VanDerPoorten,Olivier;VanDenHauwe,Robin;Eiselt,Emilie;Betti,Cecilia;Guillemyn,Karel;Chung,NgaN.;Hallé,François;Bihel,Frédéric;Schiller,PeterW.;Tourwé,Dirk;Sarret,Philippe;Gendron,Louis;Ballet,Steven[ACSMedicinalChemistryLetters,2017,vol.8,#11,p.1177-1182]

Literature

Title: Prospective study of p-[123I]iodo-L-phenylalanine and SPECT for the evaluation of newly diagnosed cerebral lesions: specific confirmation of glioma.

Journal: European journal of nuclear medicine and molecular imaging 20101201

Title: 99mTc-tetrofosmin SPECT for the evaluation of cerebral lesions.

Journal: European journal of nuclear medicine and molecular imaging 20101201

Title: Preliminary in vivo evaluation of [131I]-2-iodo-D-phenylalanine as a potential radionuclide therapeutic agent in R1M-fluc rhabdomyosarcoma tumor-bearing NuNu mice using bioluminescent imaging.

Journal: Cancer biotherapy & radiopharmaceuticals 20100401

Title: PET imaging with p-[I-124]iodo-l-phenylalanine as a new tool for diagnosis and postoperative control in patients with glioma.

Journal: Clinical nuclear medicine 20080601

Title: The use of [123I]-2-iodo-L-phenylalanine as an early radiotherapy evaluation tool: in vitro R1M rabdomyosarcoma cell and in vivo mouse experiments.

Journal: Cancer biotherapy & radiopharmaceuticals 20080401

Title: Intra-individual comparison of the human biodistribution and dosimetry of the D and L isomers of 2-[123I]iodo-phenylalanine.

Journal: Nuclear medicine communications 20071001

Title: Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging.

Journal: Cancer biotherapy & radiopharmaceuticals 20060601

Title: Comparative biodistribution study of the new tumor tracer [123I]-2-iodo-L-phenylalanine with [123I]-2-iodo-L-tyrosine.

Journal: Nuclear medicine and biology 20060101

Title: Influence of sedation and data acquisition method on tracer uptake in animal models: [123I]-2-iodo-L-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice.

Journal: Nuclear medicine and biology 20060101

Title: In vivo evaluation and dosimetry of 123I-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT, in an R1M rhabdomyosarcoma athymic mouse model.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051201

Title: In vivo characterization of 123/125I-2-iodo-L-phenylalanine in an R1M rhabdomyosarcoma athymic mouse model as a potential tumor tracer for SPECT.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050301

Title: Synthesis, radiosynthesis, and in vitro characterization of [125I]-2- iodo-L-phenylalanine in a R1M rhabdomyosarcoma cell model as a new potential tumor tracer for SPECT.

Journal: Nuclear medicine and biology 20040801

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