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168266-90-8,MFCD06199014
Catalog No.:AA00AOZ2

168266-90-8 | GR 205171

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$190.00   $133.00
- +
5mg
95%
1 week  
$388.00   $272.00
- +
10mg
95%
1 week  
$578.00   $404.00
- +
25mg
95%
1 week  
$1,035.00   $724.00
- +
50mg
95%
1 week  
$1,623.00   $1,136.00
- +
100mg
95%
1 week  
$2,195.00   $1,536.00
- +
500mg
95%
1 week  
$4,343.00   $3,040.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00AOZ2
Chemical Name:
GR 205171
CAS Number:
168266-90-8
Molecular Formula:
C21H23F3N6O
Molecular Weight:
432.4421
MDL Number:
MFCD06199014
SMILES:
COc1ccc(cc1CNC1CCCNC1c1ccccc1)n1nnnc1C(F)(F)F
Properties

Literature

Title: Gardner CJ, et al. GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regul Pept. 1996 Aug 27;65(1):45-53.

Title: Loiseau F, et al. Antidepressant-like effects of agomelatine, melatonin and the NK1 receptor antagonist GR205171 in impulsive-related behaviour in rats. Psychopharmacology (Berl). 2005 Oct;182(1):24-32. Epub 2005 Sep 29.

Title: Guiard BP, et al. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. J Neurochem. 2004 Apr;89(1):54-63.

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SDS
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