Name: Name:7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Brand: AABLOCKS
SKU: AA0037WL
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0037WL

Chemical Name: 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

CAS Number: 17306-46-6

Molecular Formula: C27H30O14

Molecular Weight: 578.5187

MDL Number: MFCD00004150

SMILES: OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(cc3=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O

Properties

Complexity: 939

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 10

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 41

Hydrogen Bond Acceptor Count: 14

Hydrogen Bond Donor Count: 8

Isotope Atom Count: 0

Rotatable Bond Count: 6

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: -0.2

Literature fold

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Journal: Bioorganic & medicinal chemistry20121115

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Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20120101

Title: Antioxidative glycosides from the leaves of Ligustrum robustum.

Journal: Journal of natural products20030601

Title: Inhibitory activity of flavonoids and tannins against HIV-1 protease.

Journal: Biological & pharmaceutical bulletin20000901

Title: Inhibition of HIV activation in latently infected cells by flavonoid compounds.

Journal: AIDS research and human retroviruses19960101

Title: Rao YK, et al. Insulin-Mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells. Evid Based Complement Alternat Med. 2011;2011:624375.

Title: Liao S, et al. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. J Cell Physiol. 2019 Aug;234(10):17600-17611.

Title: Eldahshan. O. A, et al. Rhoifolin; A Potent Antiproliferative Effect on Cancer Cell Lines. Journal of Pharmaceutical Research International, 2012, 3(1), pp. 46-53.

Title: Omama E. El-Shawi, et al. Protective Effect of Rhoifolin on Gamma Irradiation Induced Cardiac Dysfunctions in Albino Mice. Feb 15, 2014.

17306-46-6 | 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one