Title: In vitro effects of some flavones on human pyruvate kinase isoenzyme M2.
Journal: Journal of biochemical and molecular toxicology 20150301
Title: Scutellarin inhibits high glucose-induced and hypoxia-mimetic agent-induced angiogenic effects in human retinal endothelial cells through reactive oxygen species/hypoxia-inducible factor-1α/vascular endothelial growth factor pathway.
Journal: Journal of cardiovascular pharmacology 20140901
Title: Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats.
Journal: Molecules (Basel, Switzerland) 20120906
Title: Scutellarin inhibits cytochrome P450 isoenzyme 1A2 (CYP1A2) in rats.
Journal: Phytotherapy research : PTR 20120801
Title: Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.
Journal: Bioorganic & medicinal chemistry letters 20120615
Title: Research on scutellarin parenteral solution's protective effects in rats with severe acute pancreatitis and multiple organ injuries.
Journal: Inflammation 20120601
Title: [Scutellarin starch microspheres' permeability through nasal mucosa of different animals in vitro].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120301
Title: Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat.
Journal: Clinical and experimental pharmacology & physiology 20120201
Title: [Simultaneous determination of isoorientin, scutellarin and cynaroside in rat plasma and pharmacokinetics by UPLC-MS/MS].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120201
Title: Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.
Journal: The Chinese journal of physiology 20111231
Title: Preparation, characterization and evaluation of breviscapine lipid emulsions coated with monooleate-PEG-COOH.
Journal: International journal of pharmaceutics 20111215
Title: Scutellarin protects against Aβ-induced learning and memory deficits in rats: involvement of nicotinic acetylcholine receptors and cholinesterase.
Journal: Acta pharmacologica Sinica 20111201
Title: Comparative studies on interactions of baicalein, baicalin and scutellarin with lysozyme.
Journal: European journal of medicinal chemistry 20111201
Title: Scutellarin-dependent inhibition of collagen biosynthesis in cultured fibroblasts.
Journal: Natural product research 20111101
Title: Absorption and disposition of scutellarin in rats: a pharmacokinetic explanation for the high exposure of its isomeric metabolite.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111101
Title: [Simultaneous determination of protocatechuic acid, isoorientin and scutellarin in rat tissues after a single intravenous administration of compound hongcao for injection by UPLC-MS/MS].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101
Title: Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity.
Journal: The Journal of pharmacy and pharmacology 20111001
Title: Scutellarin benzyl ester partially secured the ischemic injury by its anti-apoptosis mechanism in cardiomyocytes of neonatal rats.
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20110901
Title: Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110701
Title: Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation.
Journal: Neuroscience 20110630
Title: Scutellarin blocks sodium current in freshly isolated mouse hippocampal CA1 neurons.
Journal: Neurochemical research 20110601
Title: Acute and subacute toxicological evaluation of scutellarin in rodents.
Journal: Regulatory toxicology and pharmacology : RTP 20110601
Title: Effects of scutellarin on MUC5AC mucin production induced by human neutrophil elastase or interleukin 13 on airway epithelial cells.
Journal: Journal of Korean medical science 20110601
Title: [Effect of scutellarin on expressions of nicotinic acetylcholine receptor protein and mRNA in the brains of dementia rats].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110601
Title: Metabolic and pharmacokinetic studies of scutellarin in rat plasma, urine, and feces.
Journal: Acta pharmacologica Sinica 20110501
Title: [Studies on the chemical constituents from Conyza canadensis].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110501
Title: Flavonoid composition of Juniperus oblonga Bieb.
Journal: Bulletin of experimental biology and medicine 20110401
Title: [Effect of pravastatin on transportation of scutellarin in mouse liver and its mechanism].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110301
Title: Scutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFβ1 expression and activation of p38-MAPK and ERK1/2.
Journal: British journal of pharmacology 20110201
Title: [Influence of scutellarin on oxidative stress and neuronal apoptosis of rats with dementia].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110201
Title: [Determination of four effective components from total flavonoids of Scutellaria barbata by high performance liquid chromatography].
Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110101
Title: Scutellarin attenuates human-neutrophil-elastase-induced mucus production by inhibiting the PKC-ERK signaling pathway in vitro and in vivo.
Journal: The American journal of Chinese medicine 20110101
Title: Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease.
Journal: International journal of molecular sciences 20110101
Title: Scutellarin inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells.
Journal: Oncology reports 20101101
Title: Scutellarin promotes in vitro angiogenesis in human umbilical vein endothelial cells.
Journal: Biochemical and biophysical research communications 20100910
Title: [Absorption and transportation characteristics of scutellarin and scutellarein across Caco-2 monolayer model].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100901
Title: [Evaluation of brain-targeted trendence of scutellarin nasal administration].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
Title: PEG-scutellarin prodrugs: synthesis, water solubility and protective effect on cerebral ischemia/reperfusion injury.
Journal: European journal of medicinal chemistry 20100501
Title: Scutellarin protects against lipopolysaccharide-induced acute lung injury via inhibition of NF-kappaB activation in mice.
Journal: Journal of Asian natural products research 20100301
Title: Scutellarin exerts its anti-hypertrophic effects via suppressing the Ca2+-mediated calcineurin and CaMKII signaling pathways.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100201
Title: Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100101
Title: [Advances in studies on pharmacokinetics of scutellarin and scutellarein].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201
Title: Metabolism profile of scutellarin in urine following oral administration to rats by ultra performance liquid chromatography coupled to time-of-flight mass spectrometry.
Journal: Talanta 20091115
Title: Estrogenic and neuroprotective properties of scutellarin from Erigeron breviscapus: a drug against postmenopausal symptoms and Alzheimer's disease.
Journal: Planta medica 20091101
Title: Suppression of diet-induced hypercholesterolemia by scutellarin in rats.
Journal: Planta medica 20090901
Title: Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation.
Journal: Anticancer research 20090801
Title: [Effects of doubled CO2 concentration on Erigeron breviscapus growth and its active constituent accumulation].
Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20090801
Title: [Effect of water stress on content of active constituents in Erigeron breviscaps].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501
Title: Protective effects of scutellarin against cerebral ischemia in rats: evidence for inhibition of the apoptosis-inducing factor pathway.
Journal: Planta medica 20090201
Title: Nitric oxide and catalase-sensitive relaxation by scutellarin in the mouse thoracic aorta.
Journal: Journal of cardiovascular pharmacology 20090101
Title: Separation and purification of two flavone glucuronides from Erigeron multiradiatus (Lindl.) Benth with macroporous resins.
Journal: Journal of biomedicine & biotechnology 20090101
Title: [Study on optimal harvest time of Erigeron breviscapus].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201
Title: Simultaneous determination of five main active constituents of Erigeron multiradiatus by HPLC-DAD-MS.
Journal: Journal of pharmaceutical and biomedical analysis 20081104
Title: Pulmonary delivery of scutellarin solution and mucoadhesive particles in rats.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081101
Title: Scutellarin-induced endothelium-independent relaxation in rat aorta.
Journal: Phytotherapy research : PTR 20081101
Title: Anti-inflammatory activity of the extracts and fractions from Erigeron multiradiatus through bioassay-guided procedures.
Journal: Journal of ethnopharmacology 20080926
Title: Scutellarin isolated from Erigeron multiradiatus inhibits high glucose-mediated vascular inflammation.
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080901
Title: Comparative pharmacokinetics of breviscapine liposomes in dogs, rabbits and rats.
Journal: International journal of pharmaceutics 20080709
Title: [HPLC determination of four active components in dengzhanxixin injection].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080701
Title: Effect of ion-pairing and enhancers on scutellarin skin permeability.
Journal: The Journal of pharmacy and pharmacology 20080401
Title: [Optimizing extraction process of Scutellaria barbata by golden section method].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401
Title: Plant regeneration of Erigeron breviscapus (vant.) Hand. Mazz. and its chromatographic fingerprint analysis for quality control.
Journal: Plant cell reports 20080101
Title: Mrp2-related efflux of scutellarin in the intestinal absorption in rats.
Journal: Die Pharmazie 20080101
Title: Scutellarin induced Ca(2+ ) release and blocked KCl-induced Ca(2+ ) influx in smooth muscle cells isolated from rat thoracic artery.
Journal: Journal of Asian natural products research 20080101
Title: The promoting angiogenesis and anti-inflammation effect of scutellarin on polyglycolic acid scaffold of balb/c mice model.
Journal: Journal of Asian natural products research 20080101
Title: Effects of scutellarin on apoptosis induced by cobalt chloride in PC12 cells.
Journal: The Chinese journal of physiology 20071231
Title: Separation of scutellarin from crude extracts of Erigeron breviscapus (vant.) Hand. Mazz. by macroporous resins.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
Title: Effects of scutellarin on PKCgamma in PC12 cell injury induced by oxygen and glucose deprivation.
Journal: Acta pharmacologica Sinica 20071001
Title: Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats.
Journal: Journal of cardiovascular pharmacology 20070901
Title: [Pharmacokinetic and tissue distribution study of scutellarin in rats].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801
Title: Microwave-assisted extraction of scutellarin from Erigeron breviscapus Hand-Mazz and its determination by high-performance liquid chromatography.
Journal: Analytica chimica acta 20070522
Title: Two major urinary metabolites of scutellarin in rats.
Journal: Planta medica 20070401
Title: Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death.
Journal: Journal of agricultural and food chemistry 20070321
Title: Scutellarin protects PC12 cells from oxidative stress-induced apoptosis.
Journal: Journal of Asian natural products research 20070301
Title: The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro-inflammatory cytokines in mice.
Journal: The Journal of pharmacy and pharmacology 20070101
Title: Prodrugs of scutellarin: ethyl, benzyl and N,N-diethylglycolamide ester synthesis, physicochemical properties, intestinal metabolism and oral bioavailability in the rats.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061201
Title: [Study on bile excretion of scutellarein].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001
Title: Scutellarin protects PC12 cells from oxidative stress-induced apoptosis.
Journal: Journal of Asian natural products research 20060901
Title: Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060801
Title: Synthesis, characterization and in situ intestinal absorption of different molecular weight scutellarin-PEG conjugates.
Journal: Die Pharmazie 20060801
Title: Two-step purification of scutellarin from Erigeron breviscapus (vant.) Hand. Mazz. by high-speed counter-current chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060711
Title: [Ester prodrug of scutellarin: synthesis, physicochemical property and degradation].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060701
Title: Determination of scutellarin in mouse plasma and different tissues by high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060501
Title: [The synthesis, characterization and in situ intestinal absorption of different molecular weight scutellarin-PEG conjugates].
Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20060401
Title: Determination of aglycone conjugated metabolites of scutellarin in rat plasma by HPLC.
Journal: Journal of pharmaceutical and biomedical analysis 20060213
Title: Sensitive liquid chromatography-tandem mass spectrometry method for the determination of scutellarin in human plasma: Application to a pharmacokinetic study.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060102
Title: [Pharmacokinetics of breviscapine liposomes following intravenous injection in Beagle dogs].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060101
Title: Neuroprotective effects of scutellarin on rat neuronal damage induced by cerebral ischemia/reperfusion.
Journal: Acta pharmacologica Sinica 20051201
Title: [Pharmacokinetics and metabolites of scutellarin in normal and model rats].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051101
Title: Stability of baicalin in biological fluids in vitro.
Journal: Journal of pharmaceutical and biomedical analysis 20050915
Title: Multivesicular liposome formulation for the sustained delivery of breviscapine.
Journal: International journal of pharmaceutics 20050914
Title: The anti-HIV-1 effect of scutellarin.
Journal: Biochemical and biophysical research communications 20050902
Title: The physicochemical characteristics of freeze-dried scutellarin-cyclodextrin tetracomponent complexes.
Journal: Drug development and industrial pharmacy 20050901
Title: Study on the role of hepatic first-pass elimination in the low oral bioavailability of scutellarin in rats.
Journal: Die Pharmazie 20050601
Title: [Effect of caffeic acid, seopoletin and scutellarin on rat retinal neurons in vitro].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601
Title: A possible quantitative method to improve the sensitivity of scutellarin in human plasma.
Journal: Annali di chimica 20050601
Title: Effect of scutellarin on nitric oxide production in early stages of neuron damage induced by hydrogen peroxide.
Journal: Pharmacological research 20050301
Title: In vitro studies of baicalin alone or in combination with Salvia miltiorrhiza extract as a potential anti-cancer agent.
Journal: International journal of oncology 20050101
Title: Pharmacokinetics of scutellarin and its aglycone conjugated metabolites in rats.
Journal: European journal of drug metabolism and pharmacokinetics 20050101
Title: Antagonistic effect of scutellarin on the toxicity of selenium in rat livers.
Journal: Biological trace element research 20040601
Title: Scutellarin attenuates oxidative glutamate toxicity in PC12 cells.
Journal: Planta medica 20040501
Title: Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin.
Journal: Life sciences 20040430
Title: Probing the binding of scutellarin to human serum albumin by circular dichroism, fluorescence spectroscopy, FTIR, and molecular modeling method.
Journal: Biomacromolecules 20040101
Title: Study on metabolism of scutellarin in rats by HPLC-MS and HPLC-NMR.
Journal: Journal of Asian natural products research 20031201
Title: [Pharmacokinetics of scutellarin in rabbits].
Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20031201
Title: Determination of scutellarin in rat plasma by high-performance liquid chromatography with ultraviolet detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031105
Title: [Study on the pharmacokinetics of scutellarin in dogs].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030501
Title: Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora.
Journal: Journal of natural products 20030401
Title: Structure-activity relationships of flavonoids, isolated from Scutellaria baicalensis, binding to benzodiazepine site of GABA(A) receptor complex.
Journal: Planta medica 20021201
Title: Scutellarein 4'-methyl ether glycosides as taxonomic markers in Teucridium and Tripora (Lamiaceae, Ajugoideae).
Journal: Phytochemistry 20020801
Title: [Study on effects of scutellarin on scavenging reactive oxygen].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020701
Title: Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.
Journal: Life sciences 19940101
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Title: Yang LL, et al. Differential regulation of baicalin and scutellarin on AMPK and Akt in promoting adipose cell glucose disposal. Biochim Biophys Acta. 2016 Nov 27;1863(2):598-606.
Title: Wu CY, et al. Scutellarin attenuates microglia-mediated neuroinflammation and promotes astrogliosis in cerebral ischemia - a therapeutic consideration. Curr Med Chem. 2016 Nov 18. [Epub ahead of print
Title: Li Q, et al. Scutellarin attenuates vasospasm through the Erk5-KLF2-eNOS pathway after subarachnoid hemorrhage in rats. J Clin Neurosci. 2016 Dec;34:264-270
Title: Zhao S, et al. Scutellarin inhibits RANKL-mediated osteoclastogenesis and titanium particle-induced osteolysis via suppression of NF-κB and MAPK signaling pathway. Int Immunopharmacol. 2016 Nov;40:458-465
Title: Zhang GH, et al. The anti-HIV-1 effect of scutellarin. Biochem Biophys Res Commun. 2005 Sep 2;334(3):812-6.
