Home Amines 17318-31-9
17318-31-9,MFCD00210216
Catalog No.:AA001YLU

17318-31-9 | 9-(Tetrahydrofuran-2-yl)-9h-purin-6-amine

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1mg
95%
in stock  
$14.00   $10.00
- +
5mg
95%
in stock  
$32.00   $22.00
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10mg
95%
in stock  
$51.00   $36.00
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25mg
95%
in stock  
$76.00   $54.00
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50mg
95%
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$114.00   $80.00
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250mg
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$280.00   $196.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001YLU
Chemical Name:
9-(Tetrahydrofuran-2-yl)-9h-purin-6-amine
CAS Number:
17318-31-9
Molecular Formula:
C9H11N5O
Molecular Weight:
205.2165
MDL Number:
MFCD00210216
SMILES:
Nc1ncnc2c1ncn2C1CCCO1
NSC Number:
53339
Properties
Properties
 
BP:
474.8°C at 760 mmHg  
Form:
Solid  
MP:
160-161 °C  
Solubility:
H2O: 21 mg/mL  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
239  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.4  

Downstream Synthesis Route

[1]Thompson,RobertD.;Secunda,Sherrie;Daly,JohnW.;Olsson,RayA.[JournalofMedicinalChemistry,1991,vol.34,#9,p.2877-2882]

[1]Lee,ChunHo;Kim,JoongYoung;Kim,WanJoo;Kim,YongHae[Heterocycles,1990,vol.31,#2,p.211-214]

[1]Phadtare,Shashikant;Zemlicka,Jiri[JournaloftheAmericanChemicalSociety,1989,vol.111,#15,p.5925-5931]

[1]Phadtare,Shashikant;Zemlicka,Jiri[JournaloftheAmericanChemicalSociety,1989,vol.111,#15,p.5925-5931]

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Title: Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.

Journal: British journal of pharmacology 20010701

Title: Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues.

Journal: British journal of pharmacology 20010701

Title: Monocyte membrane type 1-matrix metalloproteinase. Prostaglandin-dependent regulation and role in metalloproteinase-2 activation.

Journal: The Journal of biological chemistry 20010601

Title: Adrenomedullin suppresses fMLP-induced upregulation of CD11b of human neutrophils.

Journal: Inflammation 20010601

Title: SQ22536 and W-7 inhibit forskolin-induced cAMP elevation but not relaxation in newborn ovine pulmonary veins.

Journal: European journal of pharmacology 20010420

Title: Mechanism of action of the calcium-sensing receptor in human antral gastrin cells.

Journal: Gastroenterology 20010401

Title: cAMP-independent phosphorylation activation of CFTR by G proteins in native human sweat duct.

Journal: American journal of physiology. Cell physiology 20010301

Title: Adenosine signaling in outer medullary descending vasa recta.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Title: Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex.

Journal: International journal of molecular medicine 20010301

Title: HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contraction of the isolated rabbit aorta.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010301

Title: Further characterization of 5-HT1A receptors in the goldfish retina: role of cyclic AMP in the regulation of the in vitro outgrowth of retinal explants.

Journal: Neurochemical research 20010301

Title: Orexin A stimulates cortisol secretion from human adrenocortical cells through activation of the adenylate cyclase-dependent signaling cascade.

Journal: The Journal of clinical endocrinology and metabolism 20010201

Title: PTH and PTH-related peptide enhance steroid secretion from human adrenocortical cells.

Journal: American journal of physiology. Endocrinology and metabolism 20010201

Title: Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex.

Journal: Journal of neurophysiology 20010201

Title: Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid.

Journal: Molecular pharmacology 20010101

Title: Physiological concentrations of dopamine inhibit the proliferation and cytotoxicity of human CD4+ and CD8+ T cells in vitro: a receptor-mediated mechanism.

Journal: Neuroimmunomodulation 20010101

Title: Involvement of cyclooxygenase 2 in the protective effect of 17beta-estradiol on hypercholesterolemic rabbit aorta.

Journal: Biochemical and biophysical research communications 20000828

Title: Mechanism of PKA-dependent and lipid-raft independent stimulation of Connexin43 expression by oxytoxin in mouse embryonic stem cells.

Journal: Molecular endocrinology (Baltimore, Md.)

Title: Emery AC, et al. A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536. Mol Pharmacol. 2013 Jan;83(1):95-105.

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Tags:17318-31-9 Molecular Formula|17318-31-9 MDL|17318-31-9 SMILES|17318-31-9 9-(Tetrahydrofuran-2-yl)-9h-purin-6-amine