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Home Fluorides 174083-39-7
174083-39-7,MFCD03788501
Catalog No.:AA001ZDM

174083-39-7 | 3,5-Bis(trifluoromethyl)phenylacetyl chloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
98%
in stock  
$87.00   $61.00
- +
10g
98%
in stock  
$145.00   $102.00
- +
25g
98%
in stock  
$344.00   $241.00
- +
100g
98%
in stock  
$1,009.00   $706.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001ZDM
Chemical Name:
3,5-Bis(trifluoromethyl)phenylacetyl chloride
CAS Number:
174083-39-7
Molecular Formula:
C10H5ClF6O
Molecular Weight:
290.5895
MDL Number:
MFCD03788501
SMILES:
ClC(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Properties
Properties
 
BP:
204.8°C at 760 mmHg  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
289  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
2  
XLogP3:
4.1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:SUNPHARMACEUTICALINDUSTRIESLIMITED-WO2013/131018,2013,A1Locationinpatent:Page/Pagecolumn68;69

[2]Natsugari,Hideaki;Ikeura,Yoshinori;Kiyota,Yutaka;Ishichi,Yuji;Ishimaru,Takenori;etal.[JournalofMedicinalChemistry,1995,vol.38,#16,p.3106-3120]

[3]Young,JonathanR.;Huang,SongX.;Chen,Irene;Walsh,ThomasF.;DeVita,RobertJ.;WyvrattJr.,MatthewJ.;Goulet,MarkT.;Ren,Ning;Lo,Jane;Yang,YiTien;Yudkovitz,JoelB.;Cheng,Kang;Smith,RoyG.[BioorganicandMedicinalChemistryLetters,2000,vol.10,#15,p.1723-1727]

[4]Nanayakkara,Perli;Alper,Howard[JournalofOrganicChemistry,2004,vol.69,#14,p.4686-4691]

[5]CurrentPatentAssignee:MERCK&COINC-US2003/236250,2003,A1Locationinpatent:Page45

[6]CurrentPatentAssignee:MERCK&COINC-US2003/236250,2003,A1Locationinpatent:Page23

[7]Nichols,EvaM.;Derrick,JeffreyS.;Nistanaki,SepandK.;Smith,PeterT.;Chang,ChristopherJ.[ChemicalScience,2018,vol.9,#11,p.2952-2960]

[8]Nichols,EvaM.;Chang,ChristopherJ.[Organometallics,2019,vol.38,#6,p.1213-1218]

1027146-46-8    174083-39-7   
N-<3,5-bis(trifluoromethyl)phenylacetyl>-1,2-dihydro-N,2-dimethyl-1-oxo-4-phenyl-3-isoquinolinonemethylamine 

[1]Natsugari,Hideaki;Ikeura,Yoshinori;Kiyota,Yutaka;Ishichi,Yuji;Ishimaru,Takenori;etal.[JournalofMedicinalChemistry,1995,vol.38,#16,p.3106-3120]

78795-16-1    174083-39-7   
2-2-(3,5-bis-trifluoromethyl-phenyl)-acetylamino-4-chloro-5-nitro-benzoicacidmethylester 

[1]Young,JonathanR.;Huang,SongX.;Chen,Irene;Walsh,ThomasF.;DeVita,RobertJ.;WyvrattJr.,MatthewJ.;Goulet,MarkT.;Ren,Ning;Lo,Jane;Yang,YiTien;Yudkovitz,JoelB.;Cheng,Kang;Smith,RoyG.[BioorganicandMedicinalChemistryLetters,2000,vol.10,#15,p.1723-1727]

174083-39-7   
4-trimethylstannanylethynyl-piperidine-1-carboxylicacid<i>tert</i>-butylester 
 
4-4-(3,5-bis-trifluoromethyl-phenyl)-3-oxo-but-1-ynyl-piperidine-1-carboxylicacid<i>tert</i>-butylester 

[1]Shu,Min;Loebach,JenniferL.;Parker,KerryA.;Mills,SanderG.;Chapman,KevinT.;Shen,Dong-Ming;Malkowitz,Lorraine;Springer,MartinS.;Gould,SandraL.;DeMartino,JulieA.;Siciliano,SalvatoreJ.;DiSalvo,Jerry;Lyons,Kathy;Pivnichny,JamesV.;Kwei,GloriaY.;Carella,Anthony;Carver,Gwen;Holmes,Karen;Schleif,WilliamA.;Danzeisen,Renee;Hazuda,Daria;Kessler,Joseph;Lineberger,Janet;Miller,MichaelD.;Emini,EmilioA.[BioorganicandMedicinalChemistryLetters,2004,vol.14,#4,p.947-952]

[1]Nanayakkara,Perli;Alper,Howard[JournalofOrganicChemistry,2004,vol.69,#14,p.4686-4691]

[2]Pan,Shen;Huang,Yangen;Xu,Xiu-Hua;Qing,Feng-Ling[OrganicLetters,2017,vol.19,#17,p.4624-4627]

Literature
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Tags:174083-39-7 Molecular Formula|174083-39-7 MDL|174083-39-7 SMILES|174083-39-7 3,5-Bis(trifluoromethyl)phenylacetyl chloride