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Title: Enhanced excitability of guinea pig inferior mesenteric ganglion neurons during and following recovery from chemical colitis.
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Title: Electrophysiological characterization of sodium-activated potassium channels in NG108-15 and NSC-34 motor neuron-like cells.
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Title: Riluzole prodrugs for melanoma and ALS: design, synthesis, and in vitro metabolic profiling.
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Title: Uric acid levels predict survival in men with amyotrophic lateral sclerosis.
Journal: Journal of neurology 20120901
Title: Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.
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Title: Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis.
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Title: Mechanisms contributing to the dopamine induction of crawl-like bursting in leech motoneurons.
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Title: Amyotrophic lateral sclerosis and riluzole use during pregnancy: a case report.
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Title: North American Clinical Trials Network for the Treatment of Spinal Cord Injury: goals and progress.
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Title: Pharmacology of riluzole in acute spinal cord injury.
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Title: Riluzole for the treatment of acute traumatic spinal cord injury: rationale for and design of the NACTN Phase I clinical trial.
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Title: Translational potential of preclinical trials of neuroprotection through pharmacotherapy for spinal cord injury.
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Title: Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology.
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Title: The protective effects of riluzole on manganese-induced disruption of glutamate transporters and glutamine synthetase in the cultured astrocytes.
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Title: Pharmacotherapy to control behavioral symptoms in children with autism.
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Title: Neural precursors (NPCs) from adult L967Q mice display early commitment to 'in vitro' neuronal differentiation and hyperexcitability.
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Title: [The potential of group II metabotropic glutamate receptor antagonists as a novel antidepressant].
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Title: [Amyotrophic lateral sclerosis--diagnosis and treatment].
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Title: Factors affecting the diagnostic delay in amyotrophic lateral sclerosis.
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Title: Effect of glutamate and riluzole on manganese-induced apoptotic cell signaling in neuronally differentiated mouse P19 Cells.
Journal: Neurochemistry international 20120701
Title: Glutamatergic approaches in major depressive disorder: focus on ketamine, memantine and riluzole.
Journal: Drugs of today (Barcelona, Spain : 1998) 20120701
Title: Amyotrophic lateral sclerosis: drug therapy from the bench to the bedside.
Journal: Seminars in neurology 20120701
Title: Characterizing the effects of Eugenol on neuronal ionic currents and hyperexcitability.
Journal: Psychopharmacology 20120601
Title: Riluzole produces distinct anxiolytic-like effects in rats without the adverse effects associated with benzodiazepines.
Journal: Neuropharmacology 20120601
Title: Riluzole blocks human muscle acetylcholine receptors.
Journal: The Journal of physiology 20120515
Title: Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus.
Journal: Neurotoxicity research 20120501
Title: Riluzole treatment reduces motoneuron death induced by axotomy in newborn rats.
Journal: Journal of neurotrauma 20120501
Title: Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study.
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Title: Lithium lacks effect on survival in amyotrophic lateral sclerosis: a phase IIb randomised sequential trial.
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Title: Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease.
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Title: Drug treatment for spinal muscular atrophy type I.
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Title: Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer.
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Title: Suppression of protein aggregation by chaperone modification of high molecular weight complexes.
Journal: Brain : a journal of neurology 20120401
Title: Effects of night sleep on motor learning using transcranial magnetic stimulation.
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Title: Bursting activity in myelinated sensory neurons plays a key role in pain behavior induced by localized inflammation of the rat sensory ganglion.
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Title: Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
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Title: Modeling mitochondrial dysfunctions in the brain: from mice to men.
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Title: EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)--revised report of an EFNS task force.
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Title: The antipsychotic drug loxapine is an opener of the sodium-activated potassium channel slack (Slo2.2).
Journal: The Journal of pharmacology and experimental therapeutics 20120301
Title: Neuroprotective effects of riluzole in early phase Parkinson's disease on clinically relevant parameters in the marmoset MPTP model.
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Title: ALS patients with mutations in the SOD1 gene have an unique metabolomic profile in the cerebrospinal fluid compared with ALS patients without mutations.
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Title: A proposed staging system for amyotrophic lateral sclerosis.
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Title: Current and prospective disease-modifying therapies for amyotrophic lateral sclerosis.
Journal: Expert opinion on investigational drugs 20120301
Title: Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study.
Journal: The Lancet. Neurology 20120301
Title: The emerging science of BMAA: do cyanobacteria contribute to neurodegenerative disease?
Journal: Environmental health perspectives 20120301
Title: Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes.
Journal: European journal of pharmacology 20120227
Title: Neuronal autophagy and neurodegenerative diseases.
Journal: Experimental & molecular medicine 20120227
Title: Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice.
Journal: Psychopharmacology 20120201
Title: The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder.
Journal: Pharmacology, biochemistry, and behavior 20120201
Title: Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients.
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Title: Reviewing evidences on the management of patients with motor neuron disease.
Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20120201
Title: Neurotoxic injury pathways in differentiated mouse motor neuron-neuroblastoma hybrid (NSC-34D) cells in vitro--limited effect of riluzole on thapsigargin, but not staurosporine, hydrogen peroxide and homocysteine neurotoxicity.
Journal: Toxicology and applied pharmacology 20120115
Title: Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells.
Journal: Bioorganic & medicinal chemistry 20120115
Title: ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis.
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Title: Developing and paying for medicines for orphan indications in oncology: utilitarian regulation vs equitable care?
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Title: A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results.
Journal: Journal of neurology 20120101
Title: A panel of macroautophagy markers in lymphomonocytes of patients with amyotrophic lateral sclerosis.
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Title: Effect of prolonged riluzole exposure on cultured motoneurons in a mouse model of ALS.
Journal: Journal of neurophysiology 20120101
Title: Riluzole elevates GLT-1 activity and levels in striatal astrocytes.
Journal: Neurochemistry international 20120101
Title: Biochemical alterations associated with ALS.
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Title: [Psychotherapeutic and pharmacological treatment of pediatric obsessive-compulsive disorder].
Journal: Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie 20120101
Title: Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury.
Journal: Experimental neurology 20120101
Title: Concurrent multiple sclerosis and amyotrophic lateral sclerosis: where inflammation and neurodegeneration meet?
Journal: Journal of neuroinflammation 20120101
Title: Remarkable reduction of MAP2 in the brains of scrapie-infected rodents and human prion disease possibly correlated with the increase of calpain.
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Title: Nucleic Acid-Based Therapy Approaches for Huntington's Disease.
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Title: The use of full-setting non-invasive ventilation in the home care of people with amyotrophic lateral sclerosis-motor neuron disease with end-stage respiratory muscle failure: a case series.
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Title: Reductions in external divalent cations evoke novel voltage-gated currents in sensory neurons.
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Title: Genetic knock-down of HDAC3 does not modify disease-related phenotypes in a mouse model of Huntington's disease.
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Title: Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy.
Journal: Neuropsychiatric disease and treatment 20120101
Title: Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial.
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Title: Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail.
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Title: Left-shifted nav channels in injured bilayer: primary targets for neuroprotective nav antagonists?
Journal: Frontiers in pharmacology 20120101
Title: Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis.
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Title: Inhibition of melanogenesis by the pyridinyl imidazole class of compounds: possible involvement of the Wnt/β-catenin signaling pathway.
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Title: Antiallodynic effect of herbal medicine yokukansan on peripheral neuropathy in rats with chronic constriction injury.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Integration of subthreshold and suprathreshold excitatory barrages along the somatodendritic axis of pyramidal neurons.
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Title: Sodium channels as targets for volatile anesthetics.
Journal: Frontiers in pharmacology 20120101
Title: Riluzole neuroprotection in a Parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation.
Journal: BMC neuroscience 20120101
Title: Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis.
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Title: Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.
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Title: SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo.
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Title: Intrinsic electrophysiological properties of entorhinal cortex stellate cells and their contribution to grid cell firing fields.
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Title: Comprehensive evaluation of corticospinal tract metabolites in amyotrophic lateral sclerosis using whole-brain 1H MR spectroscopy.
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Title: Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update.
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Title: Candidate proteins, metabolites and transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) clinical study.
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Title: Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment.
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Title: Synaptic and intrinsic activation of GABAergic neurons in the cardiorespiratory brainstem network.
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Title: Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders.
Journal: Neural plasticity 20120101
Title: Treatment-resistant depression: therapeutic trends, challenges, and future directions.
Journal: Patient preference and adherence 20120101
Title: Possible association between expression of chemokine receptor-2 (CCR2) and amyotrophic lateral sclerosis (ALS) patients of North India.
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Title: Pharmacological investigation of memory restorative effect of riluzole in mice.
Journal: Indian journal of pharmacology 20120101
Title: K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration.
Journal: Frontiers in pharmacology 20120101
Title: Therapy development for spinal muscular atrophy in SMN independent targets.
Journal: Neural plasticity 20120101
Title: A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
Journal: PloS one 20120101
Title: Riluzole-induced lung injury in two patients with amyotrophic lateral sclerosis.
Journal: Internal medicine (Tokyo, Japan) 20120101
Title: A Pilot Trial of Pioglitazone HCl and Tretinoin in ALS: Cerebrospinal Fluid Biomarkers to Monitor Drug Efficacy and Predict Rate of Disease Progression.
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Title: Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.
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Title: Amyotrophic lateral sclerosis and the clinical potential of dexpramipexole.
Journal: Therapeutics and clinical risk management 20120101
Title: Riluzole-triggered GSH synthesis via activation of glutamate transporters to antagonize methylmercury-induced oxidative stress in rat cerebral cortex.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma.
Journal: PloS one 20120101
Title: Limiting spinal cord injury by pharmacological intervention.
Journal: Handbook of clinical neurology 20120101
Title: Optical reversal of halothane-induced immobility in C. elegans.
Journal: Current biology : CB 20111220
Title: Drug treatment for spinal muscular atrophy type I.
Journal: The Cochrane database of systematic reviews 20111207
Title: Hearing preservation in Guinea pigs with long-standing endolymphatic hydrops.
Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20111201
Title: Lithium treatment in amyotrophic lateral sclerosis: do we have enough trials?
Journal: Expert review of neurotherapeutics 20111201
Title: Motor neurone disease - caring for the patient in general practice.
Journal: Australian family physician 20111201
Title: G0/G1 phase arrest and apoptosis induced by manganese chloride on cultured rat astrocytes and protective effects of riluzole.
Journal: Biological trace element research 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: A review of obsessive-compulsive disorder in children and adolescents.
Journal: Dialogues in clinical neuroscience 20111201
Title: Pharmacotherapy of anxiety disorders: a critical review.
Journal: Dialogues in clinical neuroscience 20111201
Title: Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research.
Journal: Current neuropharmacology 20111201
Title: The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis.
Journal: Nature medicine 20111120
Title: Glutamatergic pathway targeting in melanoma: single-agent and combinatorial therapies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111115
Title: CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: protection by resveratrol but not riluzole.
Journal: Brain research 20111114
Title: A complex interaction between glycine/NMDA receptors and serotonergic/noradrenergic antidepressants in the forced swim test in mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20111101
Title: Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis.
Journal: Experimental neurology 20111101
Title: Dysfunction of axonal membrane conductances in adolescents and young adults with spinal muscular atrophy.
Journal: Brain : a journal of neurology 20111101
Title: Can transcriptomics cut the gordian knot of amyotrophic lateral sclerosis?
Journal: Current genomics 20111101
Title: The preclinical discovery of amyotrophic lateral sclerosis drugs.
Journal: Expert opinion on drug discovery 20111101
Title: Respiratory motoneurons and pathological conditions: lessons from hypoglossal motoneurons challenged by excitotoxic or oxidative stress.
Journal: Respiratory physiology & neurobiology 20111015
Title: ALS clinical trials: do enrolled patients accurately represent the ALS population?
Journal: Neurology 20111011
Title: Clinical diagnosis and management of amyotrophic lateral sclerosis.
Journal: Nature reviews. Neurology 20111011
Title: Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide.
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Title: Serum N-acetylaspartate level in amyotrophic lateral sclerosis.
Journal: Archives of neurology 20111001
Title: How can we improve clinical trials in amyotrophic lateral sclerosis?
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Title: Delayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures.
Journal: Neuroscience 20110908
Title: Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury.
Journal: Neuroscience letters 20110908
Title: Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: examining a more efficient trial design.
Journal: Neurology 20110906
Title: A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis.
Journal: Disease models & mechanisms 20110901
Title: Talampanel reduces the level of motoneuronal calcium in transgenic mutant SOD1 mice only if applied presymptomatically.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20110901
Title: Tetrodotoxin-, dihydropyridine-, and riluzole-resistant persistent inward current: novel sodium channels in rodent spinal neurons.
Journal: Journal of neurophysiology 20110901
Title: GPs have key role in managing motor neurone disease.
Journal: The Practitioner 20110901
Title: A systematic review of directly applied biologic therapies for acute spinal cord injury.
Journal: Journal of neurotrauma 20110801
Title: A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury.
Journal: Journal of neurotrauma 20110801
Title: Agonist-induced periodic vasomotion in rat isolated pulmonary artery.
Journal: Fundamental & clinical pharmacology 20110801
Title: Leveraging health social networking communities in translational research.
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Title: Update on degenerative ataxias.
Journal: Current opinion in neurology 20110801
Title: Clinical recognition and management of amyotrophic lateral sclerosis: the nurse's role.
Journal: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20110801
Title: Riluzole in autistic disorder.
Journal: Journal of child and adolescent psychopharmacology 20110801
Title: Species independence in brain tissue binding using brain homogenates.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701
Title: Role of endocannabinoid and glutamatergic systems in DOI-induced head-twitch response in mice.
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Title: Rhythmic intrinsic bursting neurons in human neocortex obtained from pediatric patients with epilepsy.
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Title: Initiation of treatment in early PD (evidences based).
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Title: Involvement of NMDA receptor complex in the anxiolytic-like effects of chlordiazepoxide in mice.
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Title: Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel.
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Title: Riluzole decreases flexion withdrawal reflex but not voluntary ankle torque in human chronic spinal cord injury.
Journal: Journal of neurophysiology 20110601
Title: Activation of alpha-2 noradrenergic receptors is critical for the generation of fictive eupnea and fictive gasping inspiratory activities in mammals in vitro.
Journal: The European journal of neuroscience 20110601
Title: Medical management of Parkinson's disease: focus on neuroprotection.
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Title: Emerging targets and treatments in amyotrophic lateral sclerosis.
Journal: The Lancet. Neurology 20110501
Title: Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm.
Journal: Nature biotechnology 20110501
Title: Pyrimidine-2,4,6-trione derivatives and their inhibition of mutant SOD1-dependent protein aggregation. Toward a treatment for amyotrophic lateral sclerosis.
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Title: Riluzole-induced glial cell line-derived neurotrophic factor production is regulated through fibroblast growth factor receptor signaling in rat C6 glioma cells.
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Title: Amyotrophic lateral sclerosis: one or multiple causes?
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Title: [The role of the glutamatergic system in pathophysiology and pharmacotherapy for depression: preclinical and clinical data].
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Title: Riluzole enhances ionizing radiation-induced cytotoxicity in human melanoma cells that ectopically express metabotropic glutamate receptor 1 in vitro and in vivo.
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Title: KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia.
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Title: A yeast model of FUS/TLS-dependent cytotoxicity.
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Title: Newer molecules in the treatment of schizophrenia: A clinical update.
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Title: Open-label riluzole in fragile X syndrome.
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Title: Early defect of transforming growth factor β1 formation in Huntington's disease.
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Title: Spinal cord injury: a systematic review of current treatment options.
Journal: Clinical orthopaedics and related research 20110301
Title: Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110301
Title: Riluzole pharmacokinetics in young patients with spinal muscular atrophy.
Journal: British journal of clinical pharmacology 20110301
Title: Riluzole is a potent drug to protect neonatal rat hypoglossal motoneurons in vitro from excitotoxicity due to glutamate uptake block.
Journal: The European journal of neuroscience 20110301
Title: Strategies for clinical approach to neurodegeneration in Amyotrophic lateral sclerosis.
Journal: Archives italiennes de biologie 20110301
Title: Association study of serine racemase gene with methamphetamine psychosis.
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Title: Contribution of non-inactivating Na+ current induced by oxidizing agents to the firing behavior of neuronal action potentials: experimental and theoretical studies from NG108-15 neuronal cells.
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Title: A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?
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Title: Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors.
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Title: Neuroprotective drug riluzole amplifies the heat shock factor 1 (HSF1)- and glutamate transporter 1 (GLT1)-dependent cytoprotective mechanisms for neuronal survival.
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Title: Activation of TREK currents by the neuroprotective agent riluzole in mouse sympathetic neurons.
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Title: Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.
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Title: Riluzole rapidly attenuates hyperemotional responses in olfactory bulbectomized rats, an animal model of depression.
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Title: The epidemiology and treatment of ALS: focus on the heterogeneity of the disease and critical appraisal of therapeutic trials.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20110101
Title: Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules.
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Title: Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain.
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Title: Amyotrophic lateral sclerosis: pathophysiology, diagnosis and management.
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Title: Swelling activated Cl- channels in microglia: Biophysics, pharmacology and role in glutamate release.
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Title: Pathophysiology, treatment, and animal and cellular models of human ischemic stroke.
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Title: Biomarkers in rare disorders: the experience with spinal muscular atrophy.
Journal: International journal of molecular sciences 20110101
Title: G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial.
Journal: PloS one 20110101
Title: Report on the 2nd scientific meeting of the 'Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie' (NEUROWIND e.V.) held in Motzen, Germany, Oct. 29'th - Oct. 31'st, 2010.
Journal: Experimental & translational stroke medicine 20110101
Title: Disease-related changes in the cerebrospinal fluid metabolome in amyotrophic lateral sclerosis detected by GC/TOFMS.
Journal: PloS one 20110101
Title: An immunohistochemical analysis of the neuroprotective effects of memantine, hyperbaric oxygen therapy, and brimonidine after acute ischemia reperfusion injury.
Journal: Molecular vision 20110101
Title: Blockade of persistent sodium currents contributes to the riluzole-induced inhibition of spontaneous activity and oscillations in injured DRG neurons.
Journal: PloS one 20110101
Title: FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases.
Journal: BMC neurology 20110101
Title: Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in amyotrophic lateral sclerosis (ALS) patients.
Journal: Journal of neuroinflammation 20110101
Title: GSK-3 in Neurodegenerative Diseases.
Journal: International journal of Alzheimer's disease 20110101
Title: Activating transcription factor 3, a useful marker for regenerative response after nerve root injury.
Journal: Frontiers in neurology 20110101
Title: Mcleod syndrome: Report of an Indian family with phenotypic heterogeneity.
Journal: Annals of Indian Academy of Neurology 20110101
Title: Voltage-gated channel mechanosensitivity: fact or friction?
Journal: Frontiers in physiology 20110101
Title: The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101
Title: Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease.
Journal: PloS one 20110101
Title: One universal common endpoint in mouse models of amyotrophic lateral sclerosis.
Journal: PloS one 20110101
Title: Glial cells in amyotrophic lateral sclerosis.
Journal: Neurology research international 20110101
Title: An integrative view of mechanisms underlying generalized spike-and-wave epileptic seizures and its implication on optimal therapeutic treatments.
Journal: PloS one 20110101
Title: C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress.
Journal: Molecular neurodegeneration 20110101
Title: Disease severity and progression in progressive supranuclear palsy and multiple system atrophy: validation of the NNIPPS--Parkinson Plus Scale.
Journal: PloS one 20110101
Title: Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus.
Journal: Frontiers in cellular neuroscience 20110101
Title: Riluzole prevents morphine-induced apoptosis in rat cerebral cortex.
Journal: Pharmacological reports : PR 20110101
Title: Brain-derived neurotrophic factor in patients with Huntington's disease.
Journal: PloS one 20110101
Title: Soluble beta-amyloid precursor protein is related to disease progression in amyotrophic lateral sclerosis.
Journal: PloS one 20110101
Title: Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients.
Journal: Journal of neuroinflammation 20110101
Title: Psychotherapy and medication management strategies for obsessive-compulsive disorder.
Journal: Neuropsychiatric disease and treatment 20110101
Title: The economic costs of progressive supranuclear palsy and multiple system atrophy in France, Germany and the United Kingdom.
Journal: PloS one 20110101
Title: Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic lateral sclerosis (LiCALS) [Eudract number: 2008-006891-31].
Journal: BMC neurology 20110101
Title: Amyotrophic lateral sclerosis: new genes, new models, and new mechanisms.
Journal: F1000 biology reports 20110101
Title: Future of radiation therapy for malignant melanoma in an era of newer, more effective biological agents.
Journal: OncoTargets and therapy 20110101
Title: Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells.
Journal: PloS one 20110101
Title: The lived experience of breathlessness and its implications for care: a qualitative comparison in cancer, COPD, heart failure and MND.
Journal: BMC palliative care 20110101
Title: Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes.
Journal: Frontiers in pharmacology 20110101
Title: A human TREK-1/HEK cell line: a highly efficient screening tool for drug development in neurological diseases.
Journal: PloS one 20110101
Title: Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway.
Journal: BMC medical genomics 20110101
Title: Disease and Degeneration of Aging Neural Systems that Integrate Sleep Drive and Circadian Oscillations.
Journal: Frontiers in neurology 20110101
Title: Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening.
Journal: PloS one 20110101
Title: Spinal muscular atrophy.
Journal: Orphanet journal of rare diseases 20110101
Title: A patient with amyotrophic lateral sclerosis and atypical clinical and electrodiagnostic features: a case report.
Journal: Journal of medical case reports 20110101
Title: Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis.
Journal: PloS one 20110101
Title: Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons.
Journal: Frontiers in pharmacology 20110101
Title: The Current Status of Neural Grafting in the Treatment of Huntington's Disease. A Review.
Journal: Frontiers in integrative neuroscience 20110101
Title: The importance of being profiled: improving drug candidate safety and efficacy using ion channel profiling.
Journal: Frontiers in pharmacology 20110101
Title: Oxidative stress in neurodegenerative diseases: mechanisms and therapeutic perspectives.
Journal: Oxidative medicine and cellular longevity 20110101
Title: Additive antinociceptive effects of a combination of vitamin C and vitamin E after peripheral nerve injury.
Journal: PloS one 20110101
Title: Cell-Based Neurorestorotherapy in Amyotrophic Lateral Sclerosis - Scientific Truth should Rely on Facts, but Not Conjecture.
Journal: Frontiers in integrative neuroscience 20110101
Title: Vitamin D3 deficiency differentially affects functional and disease outcomes in the G93A mouse model of amyotrophic lateral sclerosis.
Journal: PloS one 20110101
Title: Molecular motor proteins and amyotrophic lateral sclerosis.
Journal: International journal of molecular sciences 20110101
Title: Differential motor neuron impairment and axonal regeneration in sporadic and familiar amyotrophic lateral sclerosis with SOD-1 mutations: lessons from neurophysiology.
Journal: International journal of molecular sciences 20110101
Title: Managing pressures ulcers in a resource constrained situation: a holistic approach.
Journal: Indian journal of palliative care 20110101
Title: The Relationship between Intelligence and Anxiety: An Association with Subcortical White Matter Metabolism.
Journal: Frontiers in evolutionary neuroscience 20110101
Title: Amyotrophic lateral sclerosis patients show executive impairments on standard neuropsychological measures and an ecologically valid motor-free test of executive functions.
Journal: Journal of clinical and experimental neuropsychology 20101201
Title: MRS study of the effects of minocycline on markers of neuronal and microglial integrity in ALS.
Journal: Magnetic resonance imaging 20101201
Title: A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Increased survival and reinnervation of cervical motoneurons by riluzole after avulsion of the C7 ventral root.
Journal: Journal of neurotrauma 20101201
Title: Genetic determinants of amyotrophic lateral sclerosis as therapeutic targets.
Journal: CNS & neurological disorders drug targets 20101201
Title: Diagnosis, pathogenesis and therapeutic targets in amyotrophic lateral sclerosis.
Journal: CNS & neurological disorders drug targets 20101201
Title: The role of BDNF as a mediator of neuroplasticity in bipolar disorder.
Journal: Psychiatry investigation 20101201
Title: Use of antiepileptic drugs for hyperkinetic movement disorders.
Journal: Current neuropharmacology 20101201
Title: Strategy for treating motor neuron diseases using a fusion protein of botulinum toxin binding domain and streptavidin for viral vector access: work in progress.
Journal: Toxins 20101201
Title: Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.
Journal: Chemistry & biology 20101124
Title: Segmental oscillators in axial motor circuits of the salamander: distribution and bursting mechanisms.
Journal: Journal of neurophysiology 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Late-expiratory activity: emergence and interactions with the respiratory CpG.
Journal: Journal of neurophysiology 20101101
Title: Malnutrition at the time of diagnosis is associated with a shorter disease duration in ALS.
Journal: Journal of the neurological sciences 20101015
Title: Screening for inhibitors of the SOD1 gene promoter: pyrimethamine does not reduce SOD1 levels in cell and animal models.
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Title: [Amyotrophic lateral sclerosis: management of bulbar symptoms].
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Title: Amyotrophic lateral sclerosis: current practice and future treatments.
Journal: Current opinion in neurology 20101001
Title: Quantitative estimation of riluzole in human plasma by LC-ESI-MS/MS and its application to a bioequivalence study.
Journal: Analytical and bioanalytical chemistry 20101001
Title: Glutamatergic modulators: the future of treating mood disorders?
Journal: Harvard review of psychiatry 20101001
Title: Would riluzole be efficacious in the new ALS trial design?
Journal: The Lancet. Neurology 20101001
Title: Conserved genes act as modifiers of invertebrate SMN loss of function defects.
Journal: PLoS genetics 20101001
Title: Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and Ampakines.
Journal: PLoS currents 20100920
Title: Role of mechanical stress-induced glutamate signaling-associated molecules in cytodifferentiation of periodontal ligament cells.
Journal: The Journal of biological chemistry 20100903
Title: Effect of electroacupuncture on the expression of Nav1.1 in rat after acute cerebral ischemia.
Journal: Neurological research 20100901
Title: The glutamate release inhibitor Riluzole decreases migration, invasion, and proliferation of melanoma cells.
Journal: The Journal of investigative dermatology 20100901
Title: Role of neurokinin receptors and ionic mechanisms within the respiratory network of the lamprey.
Journal: Neuroscience 20100901
Title: Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
Journal: Human molecular genetics 20100901
Title: Rapid progression of amyotrophic lateral sclerosis in an acromegalic patient after surgical resection of a growth hormone-producing pituitary adenoma.
Journal: The neurologist 20100901
Title: Recent Advances on the Possible Neuroprotective Activities of Epstein-Barr Virus Oncogene BARF1 Protein in Chronic Inflammatory Disorders of Central Nervous System.
Journal: Current neuropharmacology 20100901
Title: A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation.
Journal: Current neuropharmacology 20100901
Title: Chronic progressive multiple sclerosis - pathogenesis of neurodegeneration and therapeutic strategies.
Journal: Current neuropharmacology 20100901
Title: Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trials.
Journal: Nutrients 20100901
Title: Integrative emphases on intimate, intrinsic propensity/pathological processes--causes of self recovery limits and also, subtle related targets for neuroprotectionl pleiotropicity/multimodal actions, by accessible therapeutic approaches--in spinal cord injuries.
Journal: Journal of medicine and life 20100815
Title: Pattern of spread and prognosis in lower limb-onset ALS.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20100801
Title: In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.
Journal: Human molecular genetics 20100801
Title: Pharmacological protection of hearing loss in the mouse model of endolymphatic hydrops.
Journal: The Laryngoscope 20100801
Title: Review of the use of the glutamate antagonist riluzole in psychiatric disorders and a description of recent use in childhood obsessive-compulsive disorder.
Journal: Journal of child and adolescent psychopharmacology 20100801
Title: Clinical trials for neuroprotection in ALS.
Journal: CNS & neurological disorders drug targets 20100701
Title: Amyotrophic lateral sclerosis and excitotoxicity: from pathological mechanism to therapeutic target.
Journal: CNS & neurological disorders drug targets 20100701
Title: Riluzole protects against cardiac ischaemia and reperfusion damage via block of the persistent sodium current.
Journal: British journal of pharmacology 20100701
Title: Riluzole decreases synthesis of N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells.
Journal: Brain research 20100602
Title: Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms.
Journal: Gastroenterology 20100601
Title: Pre-synaptic glutamate-induced activation of DA release in the striatum after partial nigral lesion.
Journal: Journal of neurochemistry 20100601
Title: Translational neuroimaging research in pediatric obsessive-compulsive disorder.
Journal: Dialogues in clinical neuroscience 20100601
Title: Drug treatment of obsessive-compulsive disorder.
Journal: Dialogues in clinical neuroscience 20100601
Title: Motor neurone disease: a practical update on diagnosis and management.
Journal: Clinical medicine (London, England) 20100601
Title: Ischemia-reperfusion injury of the cochlea: pharmacological strategies for cochlear protection and implications of glutamate and reactive oxygen species.
Journal: Current neuropharmacology 20100601
Title: Calcium oscillations induced by gambierol in cerebellar granule cells.
Journal: Journal of cellular biochemistry 20100515
Title: Toward more efficient clinical trials for amyotrophic lateral sclerosis.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20100503
Title: Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole.
Journal: Molecular psychiatry 20100501
Title: The role of local protein synthesis and degradation in axon regeneration.
Journal: Experimental neurology 20100501
Title: Glutamatergic modulatory therapy for Tourette syndrome.
Journal: Medical hypotheses 20100501
Title: Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial.
Journal: The Lancet. Neurology 20100501
Title: Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.
Journal: The Journal of biological chemistry 20100409
Title: Species differences in respiratory rhythm generation in rodents.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100401
Title: Altered motor cortex excitability to magnetic stimulation in alcohol withdrawal syndrome.
Journal: Alcoholism, clinical and experimental research 20100401
Title: Increase in valproic acid levels during riluzole treatment in an adolescent with autism.
Journal: Journal of child and adolescent psychopharmacology 20100401
Title: Neurotoxocariasis associated with lower motor neuron disease. Report of one case.
Journal: Revista medica de Chile 20100401
Title: Calcium signaling and neurodegeneration.
Journal: Acta naturae 20100401
Title: Differential effects of riluzole on subpopulations of adult rat dorsal root ganglion neurons in vitro.
Journal: Neuroscience 20100331
Title: P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis.
Journal: Neuroscience letters 20100326
Title: Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial.
Journal: Neurology 20100309
Title: Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats.
Journal: Brain research 20100304
Title: Past, present and future therapeutics for cerebellar ataxias.
Journal: Current neuropharmacology 20100301
Title: Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord.
Journal: Neuroscience 20100217
Title: Spinal muscular atrophy disease: a literature review for therapeutic strategies.
Journal: Journal of medicine and life 20100215
Title: Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial.
Journal: The international journal of neuropsychopharmacology 20100201
Title: Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100201
Title: Evidences for pharmacokinetic interaction of riluzole and topiramate with pilocarpine in pilocarpine-induced seizures in rats.
Journal: Epilepsy research 20100201
Title: Therapeutic options for treatment-resistant depression.
Journal: CNS drugs 20100201
Title: Calcium dysregulation in amyotrophic lateral sclerosis.
Journal: Cell calcium 20100201
Title: Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases.
Journal: Journal of medicinal chemistry 20100128
Title: Motor neuron disease: systematic reviews of treatment for ALS and SMA.
Journal: British medical bulletin 20100101
Title: Brain-targeted solid lipid nanoparticles containing riluzole: preparation, characterization and biodistribution.
Journal: Nanomedicine (London, England) 20100101
Title: The interaction of the neuroprotective compounds riluzole and phenobarbital with AMPA-type glutamate receptors: a patch-clamp study.
Journal: Pharmacology 20100101
Title: Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study.
Journal: BMC neurology 20100101
Title: Serum free fatty acids levels not associated with normal tension glaucoma.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101
Title: [Retrospective study of ALS in French military personnel].
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Title: Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline.
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Title: Riluzole, neuroprotection and amyotrophic lateral sclerosis.
Journal: Current medicinal chemistry 20100101
Title: Orchestration of 'presto' and 'largo' synchrony in up-down activity of cortical networks.
Journal: Frontiers in neural circuits 20100101
Title: Reduction of circulating endothelial cells in peripheral blood of ALS patients.
Journal: PloS one 20100101
Title: Riluzole use during pregnancy in a patient with amyotrophic lateral sclerosis: a case report.
Journal: The Journal of international medical research 20100101
Title: The role of rasagiline in the treatment of Parkinson's disease.
Journal: Clinical interventions in aging 20100101
Title: Heat shock protein 90 in neurodegenerative diseases.
Journal: Molecular neurodegeneration 20100101
Title: Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?
Journal: Frontiers in neuroscience 20100101
Title: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).
Journal: Experimental & translational stroke medicine 20100101
Title: Glutamatergic and resting-state functional connectivity correlates of severity in major depression - the role of pregenual anterior cingulate cortex and anterior insula.
Journal: Frontiers in systems neuroscience 20100101
Title: Temporal coding at the immature depolarizing GABAergic synapse.
Journal: Frontiers in cellular neuroscience 20100101
Title: [Amyotrophic lateral sclerosis].
Journal: Nederlands tijdschrift voor tandheelkunde 20100101
Title: Amyotrophic lateral sclerosis-motor neuron disease, monoclonal gammopathy, hyperparathyroidism, and B12 deficiency: case report and review of the literature.
Journal: Journal of medical case reports 20100101
Title: Protective effect of combination of sulforaphane and riluzole on glutamate-mediated excitotoxicity.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Current and emerging treatment options in the management of Friedreich ataxia.
Journal: Neuropsychiatric disease and treatment 20100101
Title: Intracerebroventricular administration of riluzole prevents morphine-induced apoptosis in the lumbar region of the rat spinal cord.
Journal: Pharmacological reports : PR 20100101
Title: Moving towards supraspinal TRPV1 receptors for chronic pain relief.
Journal: Molecular pain 20100101
Title: Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release.
Journal: PloS one 20100101
Title: Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models.
Journal: Journal of neuroinflammation 20100101
Title: Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease.
Journal: Neuropsychiatric disease and treatment 20100101
Title: Platelet serotonin level predicts survival in amyotrophic lateral sclerosis.
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Title: Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder.
Journal: Human genomics and proteomics : HGP 20100101
Title: Motor network degeneration in amyotrophic lateral sclerosis: a structural and functional connectivity study.
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Title: The human G93A-SOD1 mutation in a pre-symptomatic rat model of amyotrophic lateral sclerosis increases the vulnerability to a mild spinal cord compression.
Journal: BMC genomics 20100101
Title: Synaptically activated burst-generating conductances may underlie a group-pacemaker mechanism for respiratory rhythm generation in mammals.
Journal: Progress in brain research 20100101
Title: The persistent sodium current blocker riluzole is antiarrhythmic and anti-ischaemic in a pig model of acute myocardial infarction.
Journal: PloS one 20100101
Title: The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study.
Journal: Environmental health : a global access science source 20100101
Title: Metabotropic glutamate receptors: potential drug targets for psychiatric disorders.
Journal: The open medicinal chemistry journal 20100101
Title: Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study.
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Title: Perspectives on the treatment of the longitudinal spinal cord injury.
Journal: Frontiers in neurology 20100101
Title: Clinical and experimental advances in regeneration of spinal cord injury.
Journal: Journal of tissue engineering 20100101
Title: Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients.
Journal: Journal of affective disorders 20091201
Title: Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice.
Journal: Journal of neurophysiology 20091201
Title: Multiple system atrophy: an update.
Journal: The Lancet. Neurology 20091201
Title: Mills' syndrome: case report.
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Title: Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology.
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Title: Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive/behavioral impairment (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology.
Journal: Neurology 20091013
Title: The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders.
Journal: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20091001
Title: Recent advances in motor neuron disease.
Journal: Current opinion in neurology 20091001
Title: Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
Journal: The Journal of comparative neurology 20091001
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Interdisciplinary palliative care, including massage, in treatment of amyotrophic lateral sclerosis.
Journal: Journal of bodywork and movement therapies 20091001
Title: Do glutamatergic agents represent a new class of antidepressant drugs? Part 1.
Journal: The Journal of clinical psychiatry 20091001
Title: Spontaneous bursting activity in the developing entorhinal cortex.
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Title: Activation of p38 mitogen-activated protein kinase is required for in vivo brain-derived neurotrophic factor production in the rat hippocampus.
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Title: The protective effect of riluzole on manganese caused disruption of glutamate-glutamine cycle in rats.
Journal: Brain research 20090915
Title: A repertoire of rhythmic bursting produced by hypoglossal motoneurons in physiological and pathological conditions.
Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090912
Title: Targeting glial physiology and glutamate cycling in the treatment of depression.
Journal: Biochemical pharmacology 20090901
Title: Central administration of minocycline and riluzole prevents morphine-induced tolerance in rats.
Journal: Anesthesia and analgesia 20090901
Title: Amyotrophic lateral sclerosis (ALS): three letters that change the people's life. For ever.
Journal: Arquivos de neuro-psiquiatria 20090901
Title: Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression.
Journal: Dialogues in clinical neuroscience 20090901
Title: The neurotrophic and neuroprotective effects of psychotropic agents.
Journal: Dialogues in clinical neuroscience 20090901
Title: Evidence-based drug treatment in amyotrophic lateral sclerosis and upcoming clinical trials.
Journal: Therapeutic advances in neurological disorders 20090901
Title: Analytical studies of rapidly inactivating and noninactivating sodium currents in differentiated NG108-15 neuronal cells.
Journal: Journal of theoretical biology 20090821
Title: Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms.
Journal: Alcoholism, clinical and experimental research 20090801
Title: Neuroprotection: extrapolating from neurologic diseases to the eye.
Journal: American journal of ophthalmology 20090801
Title: Therapeutic interventions for disease progression in Huntington's disease.
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Title: A riluzole- and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones.
Journal: Pflugers Archiv : European journal of physiology 20090701
Title: Riluzole protects Huntington disease patients from brain glucose hypometabolism and grey matter volume loss and increases production of neurotrophins.
Journal: European journal of nuclear medicine and molecular imaging 20090701
Title: Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis.
Journal: Antioxidants & redox signaling 20090701
Title: The mechanism of the actions of oxaliplatin on ion currents and action potentials in differentiated NG108-15 neuronal cells.
Journal: Neurotoxicology 20090701
Title: Activation of mGluR5 induces spike afterdepolarization and enhanced excitability in medium spiny neurons of the nucleus accumbens by modulating persistent Na+ currents.
Journal: The Journal of physiology 20090701
Title: Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.
Journal: Toxicology and applied pharmacology 20090615
Title: A placebo arm is not always necessary in clinical trials of amyotrophic lateral sclerosis.
Journal: Muscle & nerve 20090601
Title: Can we eliminate placebo in ALS clinical Trials?
Journal: Muscle & nerve 20090601
Title: A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090601
Title: Riluzole induces apoptotic cell death in human prostate cancer cells via endoplasmic reticulum stress.
Journal: Anticancer research 20090601
Title: Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders.
Journal: International journal of molecular sciences 20090601
Title: Effectiveness of riluzole in suppressing spasticity in the spinal cord injured rat.
Journal: Neuroscience letters 20090515
Title: Riluzole disrupts autoresuscitation from hypothermic respiratory arrest in neonatal hamsters but not rats.
Journal: Respiratory physiology & neurobiology 20090515
Title: Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurones of rats: behavioural and electrophysiological evidence.
Journal: Neurotoxicology 20090501
Title: Riluzole protects against glutamate-induced slowing of neurofilament axonal transport.
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Title: An in vitro screening cascade to identify neuroprotective antioxidants in ALS.
Journal: Free radical biology & medicine 20090415
Title: Underlying mechanism of actions of tefluthrin, a pyrethroid insecticide, on voltage-gated ion currents and on action currents in pituitary tumor (GH3) cells and GnRH-secreting (GT1-7) neurons.
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Title: Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090401
Title: The effects of riluzole on neurological, brain biochemical, and histological changes in early and late term of sepsis in rats.
Journal: The Journal of surgical research 20090401
Title: Pathophysiology of neurodegeneration in familial amyotrophic lateral sclerosis.
Journal: Current molecular medicine 20090401
Title: Enhanced endogenous type I interferon cell-driven survival and inhibition of spontaneous apoptosis by Riluzole.
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Title: Interactions between riluzole and ABCG2/BCRP transporter.
Journal: Neuroscience letters 20090306
Title: Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors.
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Title: Mechanisms of glycine release in mouse brain stem slices.
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Title: The NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: reversal by guanosine.
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Title: Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure.
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Title: Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis.
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Title: Drug treatment for spinal muscular atrophy type I.
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Title: Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study.
Journal: Brain : a journal of neurology 20090101
Title: Amyotrophic lateral sclerosis: clinical management and research update.
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Title: Managing amyotrophic lateral sclerosis: slowing disease progression and improving patient quality of life.
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Title: Amyotrophic lateral sclerosis.
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Title: Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis.
Journal: Critical care (London, England) 20090101
Title: Early treatment with noninvasive positive pressure ventilation prolongs survival in Amyotrophic Lateral Sclerosis patients with nocturnal respiratory insufficiency.
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Title: Refractory generalized anxiety disorder.
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Title: Obsessive-compulsive disorder and related disorders: a comprehensive survey.
Journal: Annals of general psychiatry 20090101
Title: Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease.
Journal: PloS one 20090101
Title: A retrospective claims analysis of combination therapy in the treatment of adult attention-deficit/hyperactivity disorder (ADHD).
Journal: BMC health services research 20090101
Title: Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis.
Journal: Molecular neurodegeneration 20090101
Title: Brain and plasma riluzole pharmacokinetics: effect of minocycline combination.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101
Title: Drug screening of neuroprotective agents on an organotypic-based model of spinal cord excitotoxic damage.
Journal: Restorative neurology and neuroscience 20090101
Title: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development.
Journal: Current medicinal chemistry 20090101
Title: Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.
Journal: PloS one 20090101
Title: A conditioning lesion provides selective protection in a rat model of Amyotrophic Lateral Sclerosis.
Journal: PloS one 20090101
Title: GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion.
Journal: Journal of brachial plexus and peripheral nerve injury 20090101
Title: Current and emerging treatments for amyotrophic lateral sclerosis.
Journal: Neuropsychiatric disease and treatment 20090101
Title: Recent developments in multiple sclerosis therapeutics.
Journal: BMC medicine 20090101
Title: High-dose glycine treatment of refractory obsessive-compulsive disorder and body dysmorphic disorder in a 5-year period.
Journal: Neural plasticity 20090101
Title: Neuroanatomical, neurochemical, and neurodevelopmental basis of obsessive-compulsive symptoms in schizophrenia.
Journal: Indian journal of psychological medicine 20090101
Title: Chronic riluzole treatment increases glucose metabolism in rat prefrontal cortex and hippocampus.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081201
Title: Autophagy in neurodegeneration and development.
Journal: Biochimica et biophysica acta 20081201
Title: Cellular and molecular mechanisms in the long-term action of antidepressants.
Journal: Dialogues in clinical neuroscience 20081201
Title: Tianeptine: an antidepressant with memory-protective properties.
Journal: Current neuropharmacology 20081201
Title: Processing noxious information at the subnucleus reticularis dorsalis (SRD) of anesthetized cats: wind-up mechanisms.
Journal: Pain 20081115
Title: Weight loss in Huntington disease increases with higher CAG repeat number.
Journal: Neurology 20081104
Title: Causes of death amongst French patients with amyotrophic lateral sclerosis: a prospective study.
Journal: European journal of neurology 20081101
Title: Differential diagnosis in progressive infantile spastic tetraparesis.
Journal: European journal of medical research 20081027
Title: Molecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain.
Journal: Cellular and molecular life sciences : CMLS 20081001
Title: Persistent sodium current contributes to induced voltage oscillations in locomotor-related hb9 interneurons in the mouse spinal cord.
Journal: Journal of neurophysiology 20081001
Title: ALS drug development: reflections from the past and a way forward.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20081001
Title: On the role of calcium and potassium currents in circadian modulation of firing rate in rat suprachiasmatic nucleus neurons: multielectrode dish analysis.
Journal: Neuroscience research 20080901
Title: Control of neuronal persistent activity by voltage-dependent dendritic properties.
Journal: Journal of neurophysiology 20080901
Title: Riluzole in psychiatry: a systematic review of the literature.
Journal: Expert opinion on drug metabolism & toxicology 20080901
Title: Novel drugs and therapeutic targets for severe mood disorders.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080801
Title: The fraction of activated N-methyl-D-aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080801
Title: In vitro evidence for impaired neuroprotective capacities of adult mesenchymal stem cells derived from a rat model of familial amyotrophic lateral sclerosis (hSOD1(G93A)).
Journal: Experimental neurology 20080801
Title: Preface: the state of the science of all motor neuron diseases.
Journal: Physical medicine and rehabilitation clinics of North America 20080801
Title: Cognitive and behavioral impairment in amyotrophic lateral sclerosis.
Journal: Physical medicine and rehabilitation clinics of North America 20080801
Title: A strategy for developing effective amyotropic lateral sclerosis pharmacotherapy: from clinical trials to novel pharmacotherapeutic strategies.
Journal: Expert opinion on pharmacotherapy 20080801
Title: Early intervention in bipolar disorder, part II: therapeutics.
Journal: Early intervention in psychiatry 20080801
Title: Spontaneous activity in Purkinje cells: multi-electrode recording from organotypic cerebellar slice cultures.
Journal: Brain research 20080707
Title: TWIK-related two-pore domain potassium channel TREK-1 in carotid endothelium of normotensive and hypertensive mice.
Journal: Cardiovascular research 20080701
Title: Molecular mechanisms of interaction between the neuroprotective substance riluzole and GABA(A)-receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080701
Title: [Amyotrophic lateral sclerosis. Current clinical trials and underlying pathomechanisms].
Journal: Der Nervenarzt 20080601
Title: Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a series of 13 cases, with long-term follow-up.
Journal: Journal of clinical psychopharmacology 20080601
Title: Toward a better understanding of amyotrophic lateral sclerosis.
Journal: Home healthcare nurse 20080601
Title: Promising avenues of therapeutics for bipolar illness.
Journal: Dialogues in clinical neuroscience 20080601
Title: [Epidemiology and treatment of amyotrophic lateral sclerosis].
Journal: Soins; la revue de reference infirmiere 20080601
Title: Effect of the dysbindin gene on antimanic agents in patients with bipolar I disorder.
Journal: Psychiatry investigation 20080601
Title: Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder.
Journal: European journal of pharmacology 20080531
Title: An association study of riluzole serum concentration and survival and disease progression in patients with ALS.
Journal: Clinical pharmacology and therapeutics 20080501
Title: Hippocampal N-acetylaspartate concentration and response to riluzole in generalized anxiety disorder.
Journal: Biological psychiatry 20080501
Title: Riluzole blocks persistent Na+ and Ca2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro.
Journal: The European journal of neuroscience 20080501
Title: Direct effects of riluzole on 5-hydroxytryptamine (5-HT)3 receptor-activated ion currents in NCB-20 neuroblastoma cells.
Journal: Journal of pharmacological sciences 20080501
Title: Pharmacokinetics of riluzole: evidence for glucuronidation as a major metabolic pathway not associated with UGT1A1 genotype.
Journal: Biopharmaceutics & drug disposition 20080401
Title: Openers of calcium-activated potassium channels and endothelium-dependent hyperpolarizations in the guinea pig carotid artery.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080401
Title: Protection against Parkinson's disease progression: clinical experience.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20080401
Title: Local oscillations of spiking activity in organotypic spinal cord slice cultures.
Journal: The European journal of neuroscience 20080401
Title: Thalidomide causes sinus bradycardia in ALS.
Journal: Journal of neurology 20080401
Title: Diagnosis and management of motor neurone disease.
Journal: BMJ (Clinical research ed.) 20080322
Title: Plasma glutamate and glycine levels in patients with amyotrophic lateral sclerosis: the effect of riluzole treatment.
Journal: Clinical neurology and neurosurgery 20080301
Title: In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity.
Journal: Chemical research in toxicology 20080301
Title: Motor neuron disease associated with multiple myeloma.
Journal: The International journal of neuroscience 20080301
Title: [Involvement of the amygdala on place aversion induced by naloxone in single-dose morphine-treated rats].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080301
Title: Eupnea of in situ rats persists following blockers of in vitro pacemaker burster activities.
Journal: Respiratory physiology & neurobiology 20080227
Title: Neuroprotection and repair.
Journal: Journal of the neurological sciences 20080215
Title: Transition between two excitabilities in mesencephalic V neurons.
Journal: Journal of computational neuroscience 20080201
Title: Molecular insights and therapeutic targets in amyotrophic lateral sclerosis.
Journal: CNS & neurological disorders drug targets 20080201
Title: Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.
Journal: European journal of pharmacology 20080114
Title: Riluzole-induced block of voltage-gated Na+ current and activation of BKCa channels in cultured differentiated human skeletal muscle cells.
Journal: Life sciences 20080102
Title: Riluzole and D-amphetamine interactions in humans.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080101
Title: Neuroprotective effects of riluzole in Huntington's disease.
Journal: European journal of nuclear medicine and molecular imaging 20080101
Title: What role do pacemakers play in the generation of respiratory rhythm?
Journal: Advances in experimental medicine and biology 20080101
Title: Contribution of pacemaker neurons to respiratory rhythms generation in vitro.
Journal: Advances in experimental medicine and biology 20080101
Title: Timeliness of diagnosis in motor neurone disease: a population-based study.
Journal: The Ulster medical journal 20080101
Title: Design, power, and interpretation of studies in the standard murine model of ALS.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080101
Title: Molecular and cellular limits to somatosensory specificity.
Journal: Molecular pain 20080101
Title: Therapeutic potential of fluoxetine in neurological disorders.
Journal: CNS neuroscience & therapeutics 20080101
Title: Management of amyotrophic lateral sclerosis.
Journal: Drugs 20080101
Title: Social uses of personal health information within PatientsLikeMe, an online patient community: what can happen when patients have access to one another's data.
Journal: Journal of medical Internet research 20080101
Title: Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.
Journal: PloS one 20080101
Title: Riluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotection.
Journal: PloS one 20080101
Title: Dysregulated mitochondrial genes and networks with drug targets in postmortem brain of patients with posttraumatic stress disorder (PTSD) revealed by human mitochondria-focused cDNA microarrays.
Journal: International journal of biological sciences 20080101
Title: Riluzole in the treatment of mood and anxiety disorders.
Journal: CNS drugs 20080101
Title: The endocannabinoid system in amyotrophic lateral sclerosis.
Journal: Current pharmaceutical design 20080101
Title: The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile.
Journal: Nutrition journal 20080101
Title: TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.
Journal: BMC neuroscience 20080101
Title: Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury.
Journal: Neurosurgical focus 20080101
Title: Anaesthesia for ophthalmologic surgical procedures in a patient with advanced amyotrophic lateral sclerosis: a case report.
Journal: Cases journal 20080101
Title: Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats.
Journal: Molecular pain 20080101
Title: Intrinsic membrane properties and morphological characteristics of interneurons in the rat supratrigeminal region.
Journal: Journal of neuroscience research 20071201
Title: Insulin increases retinal hemorrhage in mild oxygen-induced retinopathy in the rat: inhibition by riluzole.
Journal: Investigative ophthalmology & visual science 20071201
Title: An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder.
Journal: Journal of child and adolescent psychopharmacology 20071201
Title: Oral administration of memantine prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Journal: Journal of clinical neurology (Seoul, Korea) 20071201
Title: Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071128
Title: [New options in the treatment of depression].
Journal: Fortschritte der Neurologie-Psychiatrie 20071101
Title: Evaluation of the systemic use of riluzole in post-traumatic facial nerve regeneration: experimental study in rabbits.
Journal: Acta oto-laryngologica 20071101
Title: Postnatal electrical and morphological abnormalities in lumbar motoneurons from transgenic mouse models of amyotrophic lateral sclerosis.
Journal: Archives italiennes de biologie 20071101
Title: Persistently active, pacemaker-like neurons in neocortex.
Journal: Frontiers in neuroscience 20071101
Title: [Association between amytrophic lateral sclerosis and Parkinson's disease].
Journal: Medicina clinica 20071006
Title: Minocycline and riluzole brain disposition: interactions with p-glycoprotein at the blood-brain barrier.
Journal: Journal of neurochemistry 20071001
Title: Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety.
Journal: Neuropharmacology 20071001
Title: Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20071001
Title: Clinical care of patients with amyotrophic lateral sclerosis.
Journal: The Lancet. Neurology 20071001
Title: [Clinical trials of ultra-high-dose methylcobalamin in ALS].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20071001
Title: Impairment of GH secretion in amyotrophic lateral sclerosis is not affected by riluzole treatment.
Journal: Journal of endocrinological investigation 20071001
Title: Riluzole in Huntington's disease: a 3-year, randomized controlled study.
Journal: Annals of neurology 20070901
Title: Are pacemaker properties required for respiratory rhythm generation in adult turtle brain stems in vitro?
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070801
Title: Contribution of persistent sodium current to locomotor pattern generation in neonatal rats.
Journal: Journal of neurophysiology 20070801
Title: The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia in rats.
Journal: British journal of pharmacology 20070801
Title: Good practice in the management of amyotrophic lateral sclerosis: clinical guidelines. An evidence-based review with good practice points. EALSC Working Group.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20070801
Title: Current clinical trials in amyotrophic lateral sclerosis.
Journal: Expert opinion on investigational drugs 20070801
Title: Medullary pacemaker neurons are essential for both eupnea and gasping in mammals vs. medullary pacemaker neurons are essential for gasping, but not eupnea, in mammals.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070801
Title: Medullary pacemaker neurons are essential for both eupnea and gasping in mammals vs. medullary pacemaker neurons are essential for gasping, but not eupnea, in mammals.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070801
Title: Palliative care for patients with amyotrophic lateral sclerosis: 'prepare for the worst and hope for the best'.
Journal: JAMA 20070711
Title: Comparative neuroprotective effect of sodium channel blockers after experimental spinal cord injury.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20070701
Title: Therapeutic potential of neuronal two-pore domain potassium-channel modulators.
Journal: Current opinion in investigational drugs (London, England : 2000) 20070701
Title: Anti-glutamatergic effect of riluzole: comparison with valproic acid.
Journal: Neuroscience 20070615
Title: Differential modulation by tetraethylammonium of the processes underlying network bursting in the neonatal rat spinal cord in vitro.
Journal: Neuroscience 20070608
Title: Persistent sodium current in preBotzinger neurons is not necessary for respiratory rhythm generation in the neonatal mouse?
Journal: The Journal of physiology 20070601
Title: Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice.
Journal: Anesthesia and analgesia 20070601
Title: Three soccer playing friends with simultaneous amyotrophic lateral sclerosis.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20070601
Title: Early use of non-invasive ventilation prolongs survival in subjects with ALS.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20070601
Title: Simultaneous and rapid quantitation of benazepril and benazeprilat in human plasma by high performance liquid chromatography with ultraviolet detection.
Journal: Journal of pharmaceutical and biomedical analysis 20070509
Title: Riluzole-induced oscillations in spinal networks.
Journal: Journal of neurophysiology 20070501
Title: Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.
Journal: The European journal of neuroscience 20070501
Title: Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070425
Title: Modulation of L-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model.
Journal: Behavioural brain research 20070416
Title: Recruitment of apical dendritic T-type Ca2+ channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis.
Journal: The Journal of physiology 20070415
Title: Role of persistent sodium current in mouse preBötzinger Complex neurons and respiratory rhythm generation.
Journal: The Journal of physiology 20070415
Title: Persistent inward currents in rat ventral horn neurones.
Journal: The Journal of physiology 20070415
Title: The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401
Title: Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex.
Journal: Neurobiology of disease 20070401
Title: [A strategy to develop effective ALS therapy].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20070401
Title: Efficacy of riluzole: who are the patients enrolled in the studies?
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20070401
Title: Do sodium channel blockers have neuroprotective effect after onset of ischemic insult?
Journal: Neurological research 20070401
Title: Effects of riluzole and flufenamic acid on eupnea and gasping of neonatal mice in vivo.
Journal: Neuroscience letters 20070330
Title: Amyotrophic lateral sclerosis: a global threat with a possible difference in risk across ethnicities.
Journal: Neurology 20070327
Title: Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms.
Journal: Biological psychiatry 20070315
Title: Neuroprotective agents: is effective on toxicity in glial cells?
Journal: Cellular and molecular neurobiology 20070301
Title: Opposing inward and outward conductances regulate rebound discharges in olfactory mitral cells.
Journal: Journal of neurophysiology 20070301
Title: The whisking rhythm generator: a novel mammalian network for the generation of movement.
Journal: Journal of neurophysiology 20070301
Title: Involvement of persistent Na+ current in spike initiation in primary sensory neurons of the rat mesencephalic trigeminal nucleus.
Journal: Journal of neurophysiology 20070301
Title: Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia.
Journal: Experimental neurology 20070301
Title: A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain.
Journal: Journal of neurochemistry 20070301
Title: Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma.
Journal: Cancer research 20070301
Title: Riluzole and amyotrophic lateral sclerosis survival: a population-based study in southern Italy.
Journal: European journal of neurology 20070301
Title: Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.
Journal: American journal of physiology. Heart and circulatory physiology 20070201
Title: A systematic review of the treatment studies in Huntington's disease since 1990.
Journal: Expert opinion on pharmacotherapy 20070201
Title: Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Journal: The Cochrane database of systematic reviews 20070124
Title: Delayed riluzole treatment is able to rescue injured rat spinal motoneurons.
Journal: Neuroscience 20070119
Title: Maintenance of eupnea of in situ and in vivo rats following riluzole: a blocker of persistent sodium channels.
Journal: Respiratory physiology & neurobiology 20070115
Title: Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers.
Journal: The Journal of physiology 20070101
Title: Monozygotic twins suffering from Huntington's disease show different cognitive and behavioural symptoms.
Journal: European neurology 20070101
Title: Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis.
Journal: BMC genomics 20070101
Title: Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania.
Journal: The Journal of clinical psychiatry 20070101
Title: Glutamate-modulating drugs & the treatment of mental disorders.
Journal: Journal of psychosocial nursing and mental health services 20070101
Title: Stem cell therapy for autism.
Journal: Journal of translational medicine 20070101
Title: Vitamin E deficiency and risk of equine motor neuron disease.
Journal: Acta veterinaria Scandinavica 20070101
Title: [Experimental models of amyotrophic lateral sclerosis].
Journal: Neurologia (Barcelona, Spain) 20070101
Title: [Subtle brain abnormalities in adrenomyeloneuropathy].
Journal: Journal de radiologie 20070101
Title: Outcome of sporadic amyotrophic lateral sclerosis treated with non-invasive ventilation and riluzole.
Journal: Medicina 20070101
Title: Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation.
Journal: Progress in brain research 20070101
Title: An acute, life-threatening, hypersensitivity reaction to riluzole.
Journal: Neurology 20061226
Title: Hyperimmune goat serum for amyotrophic lateral sclerosis.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20061201
Title: Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors.
Journal: Journal of clinical psychopharmacology 20061201
Title: Riluzole promotes cell survival and neurite outgrowth in rat sensory neurones in vitro.
Journal: The European journal of neuroscience 20061201
Title: Therapeutic Strategies in Huntington's Disease.
Journal: Journal of clinical neurology (Seoul, Korea) 20061201
Title: The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo.
Journal: Neuroscience 20061103
Title: Role of persistent sodium current in bursting activity of mouse neocortical networks in vitro.
Journal: Journal of neurophysiology 20061101
Title: [Management and care for patients with ALS].
Journal: Rinsho shinkeigaku = Clinical neurology 20061101
Title: Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease.
Journal: Neuroscience letters 20061030
Title: An important functional role of persistent Na+ current in carotid body hypoxia transduction.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20061001
Title: Contribution of persistent Na+ current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study.
Journal: Journal of neurophysiology 20061001
Title: Interaction of riluzole with the closed inactivated state of Kv4.3 channels.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: MCP-1 chemokine receptor CCR2 is decreased on circulating monocytes in sporadic amyotrophic lateral sclerosis (sALS).
Journal: Journal of neuroimmunology 20061001
Title: Placebo-controlled trial of riluzole in multiple system atrophy.
Journal: European journal of neurology 20061001
Title: Persistent sodium currents and repetitive firing in motoneurons of the sacrocaudal spinal cord of adult rats.
Journal: Journal of neurophysiology 20060901
Title: Glutamate release inhibition ineffective in levodopa-induced motor complications.
Journal: Movement disorders : official journal of the Movement Disorder Society 20060901
Title: Growth hormone secretion is impaired in amyotrophic lateral sclerosis.
Journal: Clinical endocrinology 20060901
Title: Lack of localization of 5-HT6 receptors on cholinergic neurons: implication of multiple neurotransmitter systems in 5-HT6 receptor-mediated acetylcholine release.
Journal: The European journal of neuroscience 20060901
Title: Rapid improvement in cortical neuronal integrity in amyotrophic lateral sclerosis detected by proton magnetic resonance spectroscopic imaging.
Journal: Journal of neurology 20060801
Title: Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones.
Journal: The Journal of physiology 20060801
Title: Consequences of misdiagnosing mitochondrial disorder.
Journal: The International journal of neuroscience 20060801
Title: Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing?
Journal: Archives of neurology 20060801
Title: Effect of riluzole on Ca2+ movement and cytotoxicity in Madin-Darby canine kidney cells.
Journal: Human & experimental toxicology 20060801
Title: Neuroprotective agents for clinical trials in ALS: a systematic assessment.
Journal: Neurology 20060711
Title: Characteristics of taurine release in slices from adult and developing mouse brain stem.
Journal: Amino acids 20060701
Title: Misdiagnosis and missed diagnoses in patients with ALS.
Journal: JAAPA : official journal of the American Academy of Physician Assistants 20060701
Title: Vitamin E intake and quality of life in amyotrophic lateral sclerosis patients: a follow-up case series study.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060701
Title: Audit of outcomes in motor neuron disease (MND) patients treated with riluzole.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20060601
Title: Factors correlated with NPPV use in ALS.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20060601
Title: Future prospects in depression research.
Journal: Dialogues in clinical neuroscience 20060601
Title: [What are the etiological medical therapies in amyotrophic lateral sclerosis?].
Journal: Revue neurologique 20060601
Title: [Etiological drug therapy for amyotrophic lateral sclerosis].
Journal: Revue neurologique 20060601
Title: Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
Journal: European journal of pharmacology 20060524
Title: Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment.
Journal: Expert reviews in molecular medicine 20060524
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Delayed amnesic syndrome after riluzole autointoxication in Huntington disease.
Journal: Neurology 20060411
Title: Norepinephrine differentially modulates different types of respiratory pacemaker and nonpacemaker neurons.
Journal: Journal of neurophysiology 20060401
Title: Specific regulation of rat glial cell line-derived neurotrophic factor gene expression by riluzole in C6 glioma cells.
Journal: Journal of neurochemistry 20060401
Title: Visual hallucinations from the addition of riluzole to memantine and bupropion.
Journal: Journal of clinical psychopharmacology 20060401
Title: Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.
Journal: European journal of pharmacology 20060327
Title: Riluzole, unlike the AMPA antagonist RPR119990, reduces motor impairment and partially prevents motoneuron death in the wobbler mouse, a model of neurodegenerative disease.
Journal: Experimental neurology 20060301
Title: Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population.
Journal: Journal of neurology, neurosurgery, and psychiatry 20060301
Title: The alkaloid alstonine: a review of its pharmacological properties.
Journal: Evidence-based complementary and alternative medicine : eCAM 20060301
Title: [Recent advances in the study of arachidonic acid-sensitive and mechano-gated tandem-pore-domain potassium channels--TREK].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060301
Title: Two-pore-domain potassium channels support anion secretion from human airway Calu-3 epithelial cells.
Journal: Pflugers Archiv : European journal of physiology 20060201
Title: The glutamate release inhibitor riluzole attenuates the formation of conditioned place aversion induced by naloxone in rats undergoing a single morphine exposure.
Journal: Brain research 20060119
Title: Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial.
Journal: Neurology 20060110
Title: Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease.
Journal: Neurobiology of disease 20060101
Title: Pharmacological characterization of ionic currents that regulate high-frequency spontaneous activity of electromotor neurons in the weakly electric fish, Apteronotus leptorhynchus.
Journal: Journal of neurobiology 20060101
Title: The metabotropic glutamate receptor subtype 5 antagonist MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions.
Journal: Neuroscience 20060101
Title: Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia.
Journal: Neuroscience 20060101
Title: Riluzole therapy for motor neurone disease: an early Australian experience (1996-2002).
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20060101
Title: [Strong suspicion of lung toxicity due to riluzole].
Journal: Archivos de bronconeumologia 20060101
Title: Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation.
Journal: Journal of neuroinflammation 20060101
Title: Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder.
Journal: NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20060101
Title: Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series.
Journal: BMC neurology 20060101
Title: COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord.
Journal: BMC neurology 20060101
Title: Pharmacological approaches to repair the injured spinal cord.
Journal: Journal of neurotrauma 20060101
Title: Widespread sensorimotor and frontal cortical atrophy in Amyotrophic Lateral Sclerosis.
Journal: BMC neurology 20060101
Title: Translating preclinical insights into effective human trials in ALS.
Journal: Biochimica et biophysica acta 20060101
Title: The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.
Journal: Biochimica et biophysica acta 20060101
Title: Pharmacological management of Huntington's disease: an evidence-based review.
Journal: Current pharmaceutical design 20060101
Title: Glutamate receptors in neuroinflammatory demyelinating disease.
Journal: Mediators of inflammation 20060101
Title: Amyotrophic lateral sclerosis: recent advances and future therapies.
Journal: Current opinion in neurology 20051201
Title: Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Journal: Investigative ophthalmology & visual science 20051201
Title: EFNS task force on management of amyotrophic lateral sclerosis: guidelines for diagnosing and clinical care of patients and relatives.
Journal: European journal of neurology 20051201
Title: Open-label trial of riluzole in generalized anxiety disorder.
Journal: The American journal of psychiatry 20051201
Title: Diagnostic investigation and multidisciplinary management in motor neuron disease.
Journal: Journal of neurology 20051201
Title: Stretch-stimulated activity of large conductance calcium-activated potassium channels in human retinal pigment epithelial cells.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20051201
Title: Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder.
Journal: The Journal of clinical psychiatry 20051101
Title: Access to palliative care for people with motor neurone disease in New Zealand: a patient's perspective.
Journal: The New Zealand medical journal 20051028
Title: Channel noise is essential for perithreshold oscillations in entorhinal stellate neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026
Title: Minocycline in amyotrophic lateral sclerosis: a pilot study.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20051001
Title: Beyond monoamines: glutamatergic function in mood disorders.
Journal: CNS spectrums 20051001
Title: Rilutek should be subsidised.
Journal: Nursing New Zealand (Wellington, N.Z. : 1995) 20051001
Title: Neuroprotective therapy in Parkinson's disease: current status and new directions from experimental and genetic clues.
Journal: Journal of clinical neurology (Seoul, Korea) 20051001
Title: Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial.
Journal: Biological psychiatry 20050901
Title: Management strategies for patients with amyotrophic lateral sclerosis from diagnosis through death.
Journal: The neurologist 20050901
Title: Glutamate modulators as novel interventions for mood disorders.
Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20050901
Title: A transitional period of Ca2+-dependent spike afterdepolarization and bursting in developing rat CA1 pyramidal cells.
Journal: The Journal of physiology 20050815
Title: Riluzole improves motor deficits and attenuates loss of striatal neurons in a sequential double lesion rat model of striatonigral degeneration (parkinson variant of multiple system atrophy).
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20050801
Title: Riluzole: a glimmer of hope in the treatment of motor neurone disease.
Journal: The Medical journal of Australia 20050801
Title: Mechanisms underlying the early phase of spike frequency adaptation in mouse spinal motoneurones.
Journal: The Journal of physiology 20050715
Title: Neuroprotective effect of riluzole in acute noise-induced hearing loss.
Journal: Neuroreport 20050713
Title: Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.
Journal: Experimental neurology 20050701
Title: Current status of clinical trials for acute spinal cord injury.
Journal: Injury 20050701
Title: Noise of the slowly inactivating Na current in suprachiasmatic nucleus neurons.
Journal: Neuroreport 20050621
Title: Glutamate inhibition in MS: the neuroprotective properties of riluzole.
Journal: Journal of the neurological sciences 20050615
Title: Lamotrigine has an anxiolytic-like profile in the rat conditioned emotional response test of anxiety: a potential role for sodium channels?
Journal: Psychopharmacology 20050601
Title: Mechanisms of Na+ and Ca2+ influx into respiratory neurons during hypoxia.
Journal: Neuropharmacology 20050601
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: [An experience nursing a patient with amyotrophic lateral sclerosis using the theory of self-care].
Journal: Hu li za zhi The journal of nursing 20050601
Title: Sodium currents in medullary neurons isolated from the pre-Bötzinger complex region.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050525
Title: Effects of riluzole on combined MPTP + 3-nitropropionic acid-induced mild to moderate striatonigral degeneration in mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20050501
Title: High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20050501
Title: Iron alters glutamate secretion by regulating cytosolic aconitase activity.
Journal: American journal of physiology. Cell physiology 20050501
Title: Persistent sodium currents in mesencephalic v neurons participate in burst generation and control of membrane excitability.
Journal: Journal of neurophysiology 20050501
Title: A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS.
Journal: Neurology 20050412
Title: Riluzole: a glimmer of hope in the treatment of motor neurone disease.
Journal: The Medical journal of Australia 20050404
Title: [11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.
Journal: Brain : a journal of neurology 20050401
Title: Simple determination of riluzole in rat brain by high-performance liquid chromatography and spectrophotometric detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325
Title: Increased persistent Na(+) current and its effect on excitability in motoneurones cultured from mutant SOD1 mice.
Journal: The Journal of physiology 20050315
Title: The effect of glutamate receptor blockers on glutamate release following spinal cord injury. Lack of evidence for an ongoing feedback cascade of damage --> glutamate release --> damage --> glutamate release --> etc.
Journal: Brain research 20050315
Title: The ALS/MND prevalence in Sweden estimated by riluzole sales statistics.
Journal: Acta neurologica Scandinavica 20050301
Title: Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence.
Journal: Addiction (Abingdon, England) 20050301
Title: Association between CYP1A2 activity and riluzole clearance in patients with amyotrophic lateral sclerosis.
Journal: British journal of clinical pharmacology 20050301
Title: New ideas for therapy in ALS.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20050301
Title: Prognostic factors for survival in amyotrophic lateral sclerosis patients treated with riluzole.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20050301
Title: An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression.
Journal: Biological psychiatry 20050215
Title: Development of novel therapies for Huntington's disease: hope and challenge.
Journal: Acta pharmacologica Sinica 20050201
Title: Advances in clinical trials for amyotrophic lateral sclerosis.
Journal: Current neurology and neuroscience reports 20050201
Title: Sodium and calcium current-mediated pacemaker neurons and respiratory rhythm generation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050112
Title: The effects of hypoxia on the modulation of human TREK-1 potassium channels.
Journal: The Journal of physiology 20050101
Title: Excitotoxic death induced by released glutamate in depolarized primary cultures of mouse cerebellar granule cells is dependent on GABAA receptors and niflumic acid-sensitive chloride channels.
Journal: The European journal of neuroscience 20050101
Title: Pharmacologic approaches to the treatment of amyotrophic lateral sclerosis.
Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20050101
Title: Glutamate transporter: an unexpected target for some antibiotics.
Journal: Molecular pain 20050101
Title: Primary progressive multiple sclerosis : current and future treatment options.
Journal: CNS drugs 20050101
Title: Inhibition of the cloned delayed rectifier K+ channels, Kv1.5 and Kv3.1, by riluzole.
Journal: Neuroscience 20050101
Title: The cost-effectiveness of early noninvasive ventilation for ALS patients.
Journal: BMC health services research 20050101
Title: Role of spinal cord glutamate transporter during normal sensory transmission and pathological pain states.
Journal: Molecular pain 20050101
Title: The use of herbal supplements and alternative therapies by patients with amyotrophic lateral sclerosis (ALS).
Journal: Journal of herbal pharmacotherapy 20050101
Title: Excitotoxicity and amyotrophic lateral sclerosis.
Journal: Neuro-degenerative diseases 20050101
Title: Clinical trials in ALS: what did we learn from recent trials in humans?
Journal: Neuro-degenerative diseases 20050101
Title: Complex genetics of amyotrophic lateral sclerosis.
Journal: American journal of human genetics 20041201
Title: Unexpected decline in survival from amyotrophic lateral sclerosis/motor neurone disease.
Journal: Journal of neurology, neurosurgery, and psychiatry 20041201
Title: Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20041201
Title: Changes in the management of ALS since the publication of the AAN ALS practice parameter 1999.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20041201
Title: [Amyotrophic lateral sclerosis. Fatal diagnosis -- how still can be helped?].
Journal: MMW Fortschritte der Medizin 20041118
Title: A validated HPLC assay to monitor riluzole plasma or serum concentrations in patients with amyotrophic lateral sclerosis.
Journal: Biomedical chromatography : BMC 20041101
Title: Cytoplasmic body myopathy masquerading as motor neuron disease.
Journal: Muscle & nerve 20041101
Title: Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2.
Journal: Experimental neurology 20041101
Title: The tolerability of riluzole in the treatment of patients with amyotrophic lateral sclerosis.
Journal: Expert opinion on drug safety 20041101
Title: Riluzole augmentation for treatment-resistant depression.
Journal: The American journal of psychiatry 20041101
Title: Modulation of AMPA receptors in spinal motor neurons by the neuroprotective agent riluzole.
Journal: Journal of neuroscience research 20041015
Title: Clinical trials of neuroprotection for Parkinson's disease.
Journal: Neurology 20041012
Title: Easier access to motor neurone drug.
Journal: Nursing New Zealand (Wellington, N.Z. : 1995) 20041001
Title: Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease.
Journal: Brain research 20040903
Title: Acid-sensitive two-pore domain potassium (K2P) channels in mouse taste buds.
Journal: Journal of neurophysiology 20040901
Title: Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients.
Journal: Journal of neurochemistry 20040901
Title: Rasagiline alone and in combination with riluzole prolongs survival in an ALS mouse model.
Journal: Journal of neurology 20040901
Title: Disease-modifying drug therapies.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040901
Title: INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons.
Journal: The European journal of neuroscience 20040801
Title: Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses.
Journal: Neuron glia biology 20040801
Title: Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia.
Journal: Neuron 20040708
Title: Neuroprotection in Parkinson's disease: an elusive goal.
Journal: Current neurology and neuroscience reports 20040701
Title: Frequency, timing and outcome of gastrostomy tubes for amyotrophic lateral sclerosis/motor neurone disease--a record linkage study from the Scottish Motor Neurone Disease Register.
Journal: Journal of neurology 20040701
Title: Stimulatory actions of caffeic acid phenethyl ester, a known inhibitor of NF-kappaB activation, on Ca2+-activated K+ current in pituitary GH3 cells.
Journal: The Journal of biological chemistry 20040625
Title: Co-treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury.
Journal: Experimental neurology 20040601
Title: Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040601
Title: Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040601
Title: Transcranial magnetic stimulation: applications for neuropsychopharmacology.
Journal: Journal of psychopharmacology (Oxford, England) 20040601
Title: Neural plasticity: consequences of stress and actions of antidepressant treatment.
Journal: Dialogues in clinical neuroscience 20040601
Title: Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking.
Journal: Dialogues in clinical neuroscience 20040601
Title: Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats.
Journal: Life sciences 20040528
Title: Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis.
Journal: Neurology 20040525
Title: Patient page. Treatment and quality of life for people with ALS.
Journal: Neurology 20040525
Title: Riluzole-induced neutropenia.
Journal: Neurology 20040511
Title: [Neuronal background two-P-domain potassium channels: molecular and functional aspects].
Journal: Medecine sciences : M/S 20040501
Title: New pharmacological strategies to restore hearing and treat tinnitus.
Journal: Acta oto-laryngologica 20040501
Title: Is the persistent sodium current a specific target of anti-absence drugs?
Journal: Neuroreport 20040429
Title: Liquid chromatographic assay for riluzole in mouse plasma and central nervous system tissues.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425
Title: Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain.
Journal: Current biology : CB 20040406
Title: Case report: Successful riluzole augmentation therapy in treatment-resistant bipolar depression following the development of rash with lamotrigine.
Journal: Psychopharmacology 20040401
Title: Riluzole restores motor activity in rats with post-traumatic peripheral neuropathy.
Journal: Neuroscience letters 20040318
Title: The epidemiology of amyotrophic lateral sclerosis (ALS/MND) in people aged 80 or over.
Journal: Age and ageing 20040301
Title: Huntington's disease: present treatments and future therapeutic modalities.
Journal: International clinical psychopharmacology 20040301
Title: Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia.
Journal: The Journal of clinical investigation 20040215
Title: Effects of axonal injury on ganglion cell survival and glutamate homeostasis.
Journal: Brain research bulletin 20040215
Title: Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons.
Journal: Journal of neurophysiology 20040201
Title: Pathogenesis of Parkinson's disease: prospects of neuroprotective and restorative therapies.
Journal: Molecular neurobiology 20040201
Title: [Physiopathology of ALS: therapeutic approach].
Journal: Revue neurologique 20040201
Title: Riluzole enhances glutamate uptake in rat astrocyte cultures.
Journal: Cellular and molecular neurobiology 20040201
Title: Riluzole-induced methemoglobinemia.
Journal: Annals of emergency medicine 20040201
Title: Neurochemical changes of the extracellular concentrations of glutamate and aspartate in the nucleus accumbens of rats after chronic administration of morphine.
Journal: European journal of pharmacology 20040112
Title: Selective effects of potassium elevations on glutamate signaling and action potential conduction in hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040107
Title: An open-label trial of riluzole in patients with treatment-resistant major depression.
Journal: The American journal of psychiatry 20040101
Title: Neuropsychotherapeutics in the UK: what has been the impact of NICE on prescribing?
Journal: CNS drugs 20040101
Title: Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes).
Journal: Neuroscience 20040101
Title: Effect of riluzole on dyskinesia and duration of the on state in Parkinson disease patients: a double-blind, placebo-controlled pilot study.
Journal: Clinical neuropharmacology 20040101
Title: [Tolerability of riluzole: a review of the literature].
Journal: La Clinica terapeutica 20040101
Title: Riluzole enhances the anti-seizure action of conventional antiepileptic drugs against pentetrazole-induced convulsions in mice.
Journal: Polish journal of pharmacology 20040101
Title: Prognosis in amyotrophic lateral sclerosis: a population-based study.
Journal: Neurology 20031223
Title: Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study.
Journal: Neurology 20031209
Title: The management of motor neurone disease.
Journal: Journal of neurology, neurosurgery, and psychiatry 20031201
Title: Riluzole suppresses experimental autoimmune encephalomyelitis: implications for the treatment of multiple sclerosis.
Journal: Brain research 20031107
Title: Riluzole inhibits spontaneous Ca2+ signaling in neuroendocrine cells by activation of K+ channels and inhibition of Na+ channels.
Journal: British journal of pharmacology 20031101
Title: A phase 1 trial of riluzole in spinal muscular atrophy.
Journal: Archives of neurology 20031101
Title: Effect of riluzole (Rilutek) treatment on plasma amino acid percentages in amyotrophic lateral sclerosis patients.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20031101
Title: Riluzole serum concentrations in patients with ALS: associations with side effects and symptoms.
Journal: Neurology 20031028
Title: Hypersensitivity pneumonitis possibly caused by riluzole therapy in ALS.
Journal: Neurology 20031028
Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Journal: Journal of medicinal chemistry 20031009
Title: The use of the potassium channel activator riluzole to test whether potassium channels mediate the capacity of isoflurane to produce immobility.
Journal: Anesthesia and analgesia 20031001
Title: Riluzole attenuates spinal muscular atrophy disease progression in a mouse model.
Journal: Muscle & nerve 20031001
Title: Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996-2000.
Journal: Journal of neurology, neurosurgery, and psychiatry 20030901
Title: Riluzole for ALS: what is the evidence?
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030901
Title: Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030901
Title: Multiple system atrophy: an update.
Journal: Movement disorders : official journal of the Movement Disorder Society 20030901
Title: ALS treatment strikes out while trying for a homer: the topiramate trial.
Journal: Neurology 20030826
Title: Intrinsic spontaneous activity and subthreshold oscillations in neurones of the rat dorsal column nuclei in culture.
Journal: The Journal of physiology 20030815
Title: Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials?
Journal: Current opinion in neurology 20030801
Title: Huntington's disease: prospects for neuroprotective therapy 10 years after the discovery of the causative genetic mutation.
Journal: Current opinion in neurology 20030801
Title: Differential responsiveness of rat striatal nerve endings to the mitochondrial toxin 3-nitropropionic acid: implications for Huntington's disease.
Journal: The European journal of neuroscience 20030801
Title: Riluzole and blood pressure in multiple system atrophy.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20030801
Title: Ulcerative colitis and motor neurone disease: causal or coincidental?
Journal: Singapore medical journal 20030801
Title: A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine: effects on CSF glutamate, aspartate, branched-chain amino acid levels and clinical parameters.
Journal: Acta neurologica Scandinavica 20030701
Title: Riluzole, an inhibitor of glutamatergic transmission, suppresses levodopa-induced rotations in 6-hydroxydopamine-lesioned rats.
Journal: Pharmacology & toxicology 20030701
Title: Endogenous rhythm generation in the pre-Bötzinger complex and ionic currents: modelling and in vitro studies.
Journal: The European journal of neuroscience 20030701
Title: Effects of intermediate-conductance Ca2+-activated K+ channel modulators on human prostate cancer cell proliferation.
Journal: European journal of pharmacology 20030627
Title: Actions of the sodium channel inhibitor 202W92 on rat midbrain dopaminergic neurons.
Journal: Synapse (New York, N.Y.) 20030601
Title: Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder.
Journal: Psychopharmacology 20030501
Title: Efficacy, safety and cost of new drugs acting on the central nervous system.
Journal: European journal of clinical pharmacology 20030501
Title: Efficient three-drug cocktail for disease induced by mutant superoxide dismutase.
Journal: Annals of neurology 20030401
Title: Large-conductance Ca2+- activated K+ channels:physiological role and pharmacology.
Journal: Current medicinal chemistry 20030401
Title: Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401
Title: An outcome study of riluzole in amyotrophic lateral sclerosis--a population-based study in Ireland, 1996-2000.
Journal: Journal of neurology 20030401
Title: Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.
Journal: The Journal of pharmacology and experimental therapeutics 20030301
Title: Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
Title: Interferon beta-1a in primary progressive multiple sclerosis.
Journal: Journal of the neurological sciences 20030215
Title: Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells.
Journal: The Journal of biological chemistry 20030207
Title: Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201
Title: Drug therapy for amyotrophic lateral sclerosis: Where are we now?
Journal: IDrugs : the investigational drugs journal 20030201
Title: Amyotrophic lateral sclerosis: progress and prospects for treatment.
Journal: Drugs 20030101
Title: Pharmacology of neuronal background potassium channels.
Journal: Neuropharmacology 20030101
Title: Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice.
Journal: Neuroscience 20030101
Title: Prospects for the pharmacotherapy of amyotrophic lateral sclerosis : old strategies and new paradigms for the third millennium.
Journal: CNS drugs 20030101
Title: Effect of riluzole on MK-801 and amphetamine-induced hyperlocomotion.
Journal: Neuropsychobiology 20030101
Title: Involvement of glutamate in ischemic neurodegeneration in isolated retina.
Journal: Visual neuroscience 20030101
Title: Pharmacology of transcranial direct current stimulation: missing effect of riluzole.
Journal: Supplements to Clinical neurophysiology 20030101
Title: Early symptom progression rate is related to ALS outcome: a prospective population-based study.
Journal: Neurology 20021224
Title: An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1.
Journal: The Journal of biological chemistry 20021220
Title: The crude extract from the sea anemone, Bunodosoma caissarum elicits convulsions in mice: possible involvement of the glutamatergic system.
Journal: Toxicon : official journal of the International Society on Toxinology 20021201
Title: The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: a pilot study.
Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20021201
Title: Management of motor neurone disease.
Journal: Postgraduate medical journal 20021201
Title: Effect of riluzole on cytosolic Ca2+ increase in human osteosarcoma cells.
Journal: Pharmacology 20021101
Title: Interaction of high concentrations of riluzole with recombinant skeletal muscle sodium channels and adult-type nicotinic receptor channels.
Journal: Muscle & nerve 20021001
Title: Therapeutic developments in the treatment of amyotrophic lateral sclerosis.
Journal: Expert opinion on investigational drugs 20021001
Title: Molecular and cellular mechanism of glutamate receptors in relation to amyotrophic lateral sclerosis.
Journal: Current drug targets. CNS and neurological disorders 20021001
Title: Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915
Title: Controversies about databases.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020901
Title: Limitations of inferences from observational databases in amyotrophic lateral sclerosis: all that glitters is not gold.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020901
Title: Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole.
Journal: European journal of pharmacology 20020802
Title: Molsidomine potentiates the protective activity of GYKI 52466, a non-NMDA antagonist, MK-801, a non-competitive NMDA antagonist, and riluzole against electroconvulsions in mice.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020801
Title: Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801
Title: Sodium channel-blocking agents are not of benefit to rats with kaolin-induced hydrocephalus.
Journal: Neurosurgery 20020801
Title: Early symptom progression rate is related to ALS outcome: a prospective population-based study.
Journal: Neurology 20020709
Title: Lamotrigine derivatives and riluzole inhibit INa,P in cortical neurons.
Journal: Neuroreport 20020702
Title: Effect of Riluzole on serum amino acids in patients with amyotrophic lateral sclerosis.
Journal: Acta neurologica Scandinavica 20020701
Title: Effect of chronic treatment with riluzole on the nigrostriatal dopaminergic system in weaver mutant mice.
Journal: Experimental neurology 20020701
Title: Glutamate transporters and retinal excitotoxicity.
Journal: Glia 20020701
Title: Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020701
Title: A comparison of the anti-nociceptive effects of voltage-activated Na+ channel blockers in the formalin test.
Journal: European journal of pharmacology 20020612
Title: Therapies in amyotrophic lateral sclerosis-beyond riluzole.
Journal: Current opinion in pharmacology 20020601
Title: Respiratory rhythm: an emergent network property?
Journal: Neuron 20020530
Title: Riluzole treatment in advanced ALS.
Journal: Journal of neurology 20020501
Title: A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis.
Journal: Journal of neurology 20020501
Title: A sequential procedure for comparing two experimental treatments with a control.
Journal: Journal of biopharmaceutical statistics 20020501
Title: Sample size calculation for a proof of concept study.
Journal: Journal of biopharmaceutical statistics 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Emerging strategies for drug development in motor neuron disease.
Journal: Expert opinion on investigational drugs 20020401
Title: Workshop on primary progressive multiple sclerosis: meeting summary.
Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20020401
Title: Interaction between vanilloid and glutamate receptors in the central modulation of nociception.
Journal: European journal of pharmacology 20020329
Title: Kainate-induced currents in rat cortical neurons in culture are modulated by riluzole.
Journal: Synapse (New York, N.Y.) 20020315
Title: Riluzole and olanzapine in Huntington's disease.
Journal: European journal of neurology 20020301
Title: Is glutamate involved in transient lower esophageal sphincter relaxations?
Journal: Digestive diseases and sciences 20020301
Title: A double-blind, placebo-controlled and longitudinal study of riluzole in early Parkinson's disease.
Journal: Parkinsonism & related disorders 20020301
Title: How useful are retrospective studies in evaluating therapeutic interventions?
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020301
Title: Prognostic modelling of therapeutic interventions in amyotrophic lateral sclerosis.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020301
Title: Long-term safety of riluzole in amyotrophic lateral sclerosis.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020301
Title: Changes in motor unit numbers in patients with ALS: a longitudinal study using the adapted multiple point stimulation method.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020301
Title: ALS, motor neuron disease, and related disorders: a personal approach to diagnosis and management.
Journal: Seminars in neurology 20020301
Title: Enhancing synaptic plasticity and cellular resilience to develop novel, improved treatments for mood disorders.
Journal: Dialogues in clinical neuroscience 20020301
Title: Neuroprotective agent riluzole potentiates postsynaptic GABA(A) receptor function.
Journal: Neuropharmacology 20020201
Title: Contribution of presynaptic Na(+) channel inactivation to paired-pulse synaptic depression in cultured hippocampal neurons.
Journal: Journal of neurophysiology 20020201
Title: Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones.
Journal: British journal of pharmacology 20020201
Title: Apraxia of eyelid closure in Huntington's disease.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020201
Title: Neuroprotective effect of riluzole in a primate model of Parkinson's disease: behavioral and histological evidence.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020101
Title: Riluzole therapy in cervical dystonia.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020101
Title: Adjunctive modafinil in ALS.
Journal: The Journal of neuropsychiatry and clinical neurosciences 20020101
Title: Riluzole rescues cochlear sensory cells from acoustic trauma in the guinea-pig.
Journal: Neuroscience 20020101
Title: Cost effectiveness of treatments for amyotrophic lateral sclerosis: a review of the literature.
Journal: PharmacoEconomics 20020101
Title: A fair innings for NICE?
Journal: PharmacoEconomics 20020101
Title: Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Journal: The Cochrane database of systematic reviews 20020101
Title: [Tolerance of riluzole in a phase IIIb clinical trial].
Journal: Therapie 20020101
Title: Voltage-gated sodium ion channels in prostate cancer: expression and activity.
Journal: Anticancer research 20020101
Title: Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Journal: Molecular psychiatry 20020101
Title: Measures of quality of life: pro.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020101
Title: Survival endpoint: pro.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020101
Title: Cost effectiveness: summary.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020101
Title: Secondary injury mechanisms of spinal cord trauma: a novel therapeutic approach for the management of secondary pathophysiology with the sodium channel blocker riluzole.
Journal: Progress in brain research 20020101
Title: Amyotrophic lateral sclerosis: practical aspects of care.
Journal: The journal of spinal cord medicine 20020101
Title: Disease progression in amyotrophic lateral sclerosis. Identifying the cost-utility of riluzole by disease stage.
Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20020101
Title: Differential cortico-motoneuron vulnerability after chronic mitochondrial inhibition in vitro and the role of glutamate receptors.
Journal: Brain research 20011220
Title: Amyotrophic lateral sclerosis associated with pregnancy.
Journal: Neurology India 20011201
Title: Neuroprotective effect of riluzole in MPTP-treated mice.
Journal: Brain research 20011109
Title: Riluzole suppresses post-sigh, but not spontaneous apnoeas during sleep in rats.
Journal: The Journal of pharmacy and pharmacology 20011101
Title: Riluzole reduces hyperactivity of subthalamic neurons induced by unilateral 6-OHDA lesion in the rat brain.
Journal: Movement disorders : official journal of the Movement Disorder Society 20011101
Title: The cost utility analysis of riluzole for the treatment of amyotrophic lateral sclerosis in the UK.
Journal: Journal of the neurological sciences 20011015
Title: Inter- and intraindividual variability of riluzole serum concentrations in patients with ALS.
Journal: Journal of the neurological sciences 20011015
Title: Amyotrophic lateral sclerosis care in Italy: a nationwide study in neurological centers.
Journal: Journal of the neurological sciences 20011015
Title: Riluzole (2-amino-6-trifluoromethoxy benzothiazole) attenuates MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice.
Journal: Neuroscience letters 20011012
Title: Neuroprotective agent riluzole dramatically slows inactivation of Kv1.4 potassium channels by a voltage-dependent oxidative mechanism.
Journal: The Journal of pharmacology and experimental therapeutics 20011001
Title: Amyotrophic lateral sclerosis: current understanding.
Journal: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20011001
Title: Riluzole in Huntington's disease (HD): an open label study with one year follow up.
Journal: Journal of neurology 20011001
Title: Intoxication with riluzole in Huntington's disease.
Journal: Neurology 20010925
Title: Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes.
Journal: Neuroscience letters 20010914
Title: Prognostic value of decremental responses to repetitive nerve stimulation in ALS patients.
Journal: Neurology 20010911
Title: Riluzole for motor neurone disease. Reply from chairman of appraisal committee at NICE.
Journal: BMJ (Clinical research ed.) 20010908
Title: Any placebo controlled trial of riluzole would surely be unethical now.
Journal: BMJ (Clinical research ed.) 20010908
Title: Mechanisms of cell death and treatment prospects in motor neuron disease.
Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20010901
Title: The Rilutek (riluzole) Global Early Access Programme: an open-label safety evaluation in the treatment of amyotrophic lateral sclerosis.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20010901
Title: Effect of riluzole on the acquisition and expression of amygdala kindling.
Journal: Epilepsy research 20010801
Title: [Amyotrophic lateral sclerosis].
Journal: Deutsche medizinische Wochenschrift (1946) 20010727
Title: Riluzole-induced acute pancreatitis.
Journal: The American journal of gastroenterology 20010701
Title: Characteristics of hippocampal glycine release in cell-damaging conditions in the adult and developing mouse.
Journal: Neurochemical research 20010701
Title: Glutamate N-methyl-D-aspartate receptor blockade prevents induction of GAP-43 after focal ischemia in rats.
Journal: Neuroscience letters 20010608
Title: Effects of riluzole on N-methyl-D-aspartate-induced tyrosine phosphorylation in the rat hippocampus.
Journal: Brain research 20010608
Title: Pharmacological modulation of SK3 channels.
Journal: Neuropharmacology 20010601
Title: The treatment of motor neurone disease.
Journal: The Practitioner 20010601
Title: Clinical trials in ALS: an overview.
Journal: Seminars in neurology 20010601
Title: Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells.
Journal: Archives of toxicology 20010601
Title: Riluzole for motor neurone disease. More trials are needed.
Journal: BMJ (Clinical research ed.) 20010526
Title: Riluzole for motor neurone disease. Large, more economical trial is needed.
Journal: BMJ (Clinical research ed.) 20010526
Title: Riluzole for motor neurone disease. Ambiguous diagnostic criteria mean that wide variations in elgibility may still persist.
Journal: BMJ (Clinical research ed.) 20010526
Title: Motor neuron disease.
Journal: Physical medicine and rehabilitation clinics of North America 20010501
Title: [Hepatotoxicity of medications].
Journal: Presse medicale (Paris, France : 1983) 20010414
Title: Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole.
Journal: Journal of neurosurgery 20010401
Title: Effects of riluzole on cortical excitability in patients with amyotrophic lateral sclerosis.
Journal: Annals of neurology 20010401
Title: Interaction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channels.
Journal: European journal of pharmacology 20010301
Title: Clinical trials: the past, a lesson for the future.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20010301
Title: Slowing down ALS--is this good or bad?
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20010301
Title: Examining the evidence about treatment in ALS/MND.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20010301
Title: A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20010301
Title: The effect of riluzole treatment in rats on the survival of injured adult and grafted embryonic motoneurons.
Journal: The European journal of neuroscience 20010101
Title: The glutamate antagonist riluzole and its effects upon basal and stress-induced activity of the human hypothalamus-pituitary-adrenocortical system in elderly subjects.
Journal: Neuropsychobiology 20010101
Title: Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Journal: The Cochrane database of systematic reviews 20010101
Title: Multiple system atrophy: pathophysiology and management.
Journal: CNS drugs 20010101
Title: The pathogenesis of ALS: implications for treatment strategies.
Journal: Neurologia i neurochirurgia polska 20010101
Title: Pharmacological treatment of ALS.
Journal: Neurologia i neurochirurgia polska 20010101
Title: [Symptomatic treatment and palliative care of ALS].
Journal: Neurologia i neurochirurgia polska 20010101
Title: The clinical effectiveness and cost-effectiveness of riluzole for motor neurone disease: a rapid and systematic review.
Journal: Health technology assessment (Winchester, England) 20010101
Title: The role of glutamatergic transmission in the pathogenesis of levodopa-induced dyskinesias. Potential therapeutic approaches.
Journal: Neurologia i neurochirurgia polska 20010101
Title: The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK.
Journal: Molecular pharmacology 20000501
Title: Blood pressure elevations in riluzole-treated patients with amyotrophic lateral sclerosis.
Journal: European neurology 20000101
Title: Riluzole for levodopa-induced dyskinesias in advanced Parkinson's disease.
Journal: Lancet (London, England) 19990522
Title: Riluzole improves functional recovery after ischemia in the rat retina.
Journal: Investigative ophthalmology & visual science 19990301
Title: Acute hepatitis after riluzole administration.
Journal: Journal of hepatology 19990301
Title: Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons.
Journal: Journal of neurochemistry 19990201
Title: Renal tubular impairment during riluzole therapy.
Journal: Neurology 19990201
Title: Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels.
Journal: The Journal of pharmacology and experimental therapeutics 19970801
Title: Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
Journal: Annals of neurology 19960201
Title: He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA(A) receptor function. Neuropharmacology. 2002 Feb;42(2):199-209.
Title: Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51.
