Title: Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators.
Journal: Journal of the American Chemical Society 20160601
Title: Evaluation of in vitro absorption, distribution, metabolism, and excretion (ADME) properties of mitragynine, 7-hydroxymitragynine, and mitraphylline.
Journal: Planta medica 20140501
Title: Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20140301
Title: Analysis of mitragynine and metabolites in human urine for detecting the use of the psychoactive plant kratom.
Journal: Journal of analytical toxicology 20120101
Title: Involvement of mu-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa.
Journal: European journal of pharmacology 20061107
Title: Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa.
Journal: Life sciences 20051119
Title: Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa.
Journal: Chemical & pharmaceutical bulletin 20040801
Title: Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa.
Journal: Life sciences 20040312
Title: Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands.
Journal: Journal of medicinal chemistry 20020425
