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Home Amines 175137-08-3
175137-08-3,MFCD00068133
Catalog No.:AA002077

175137-08-3 | Methyl 3-amino-5-(4-fluorophenyl)thiophene-2-carboxylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$62.00   $44.00
- +
5g
97%
in stock  
$211.00   $148.00
- +
10g
97%
in stock  
$361.00   $253.00
- +
25g
97%
in stock  
$710.00   $497.00
- +
100g
97%
in stock  
$1,640.00   $1,148.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002077
Chemical Name:
Methyl 3-amino-5-(4-fluorophenyl)thiophene-2-carboxylate
CAS Number:
175137-08-3
Molecular Formula:
C12H10FNO2S
Molecular Weight:
251.2767
MDL Number:
MFCD00068133
SMILES:
COC(=O)c1sc(cc1N)c1ccc(cc1)F
Properties
Properties
 
BP:
438.8°C at 760 mmHg  
Form:
Solid  
MP:
153-155°C  
Stability:
Stench  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
282  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.4  

Downstream Synthesis Route

[1]Baxter,Andrew;Brough,Steve;Cooper,Anne;Floettmann,Eike;Foster,Steve;Harding,Christine;Kettle,Jason;McInally,Tom;Martin,Craig;Mobbs,Michelle;Needham,Maurice;Newham,Pete;Paine,Stuart;St-Gallay,Steve;Salter,Sylvia;Unitt,John;Xue,Yafeng[BioorganicandMedicinalChemistryLetters,2004,vol.14,#11,p.2817-2822]

[1]Patent:WO2012/153154,2012,A1.Locationinpatent:Page/Pagecolumn40-41

[1]BulletinoftheKoreanChemicalSociety,2016,vol.37,p.1204-1210

[1]Romagnoli,Romeo;Prencipe,Filippo;Oliva,Paola;Baraldi,Stefania;Baraldi,PierGiovanni;SchiaffinoOrtega,Santiago;Chayah,Mariem;KimatraiSalvador,Maria;Lopez-Cara,LuisaCarlota;Brancale,Andrea;Ferla,Salvatore;Hamel,Ernest;Ronca,Roberto;Bortolozzi,Roberta;Mariotto,Elena;Mattiuzzo,Elena;Viola,Giampietro[JournalofMedicinalChemistry,2019,vol.62,#3,p.1274-1290]

Literature
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SDS
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Tags:175137-08-3 Molecular Formula|175137-08-3 MDL|175137-08-3 SMILES|175137-08-3 Methyl 3-amino-5-(4-fluorophenyl)thiophene-2-carboxylate