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1759-53-1,MFCD00001287
Catalog No.:AA00217O

1759-53-1 | Cyclopropanecarboxylic acid

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10g
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25g
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100g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00217O
Chemical Name:
Cyclopropanecarboxylic acid
CAS Number:
1759-53-1
Molecular Formula:
C4H6O2
Molecular Weight:
86.0892
MDL Number:
MFCD00001287
SMILES:
OC(=O)C1CC1
NSC Number:
1112
Properties
Properties
 
BP:
183°C at 760 mmHg  
Form:
Liquid  
MP:
14-17 °C(lit.)  
Refractive Index:
n20/D 1.438(lit.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
73.6  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.6  

Literature

Title: Enantio- and diastereocontrolled conversion of chiral epoxides to trans-cyclopropane carboxylates: application to the synthesis of cascarillic acid, grenadamide and L-(-)-CCG-II.

Journal: Organic & biomolecular chemistry 20120914

Title: Stereoselective synthesis of sugar fused β-disubstituted γ-butyro-lactones: C-spiro-glycosides from 1,2-cyclopropanecarboxylated sugars.

Journal: Chemical communications (Cambridge, England) 20120118

Title: Microbial detoxification of bifenthrin by a novel yeast and its potential for contaminated soils treatment.

Journal: PloS one 20120101

Title: Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes.

Journal: Journal of the American Chemical Society 20111214

Title: Cyclopropanation with gold(I) carbenes by retro-Buchner reaction from cycloheptatrienes.

Journal: Journal of the American Chemical Society 20110810

Title: Review of pesticide urinary biomarker measurements from selected US EPA children's observational exposure studies.

Journal: International journal of environmental research and public health 20110501

Title: Synthesis of (S)-7-amino-5-azaspiro[2.4]heptane via highly enantioselective hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropanecarboxylates.

Journal: The Journal of organic chemistry 20110415

Title: Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.

Journal: The Journal of biological chemistry 20110325

Title: 3-[(E)-2-Chloro-3,3,3-trifluoro-prop-1-en-1-yl]-N-(2-fluoro-phen-yl)-2,2-dimethyl-cyclo-propane-1-carboxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: 3-[(E)-2-Chloro-3,3,3-trifluoro-prop-1-en-1-yl]-N-(2-chloro-phen-yl)-2,2-dimethyl-cyclo-propane-1-carboxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Fish oil consumption prevents glucose intolerance and hypercorticosteronemy in footshock-stressed rats.

Journal: Lipids in health and disease 20110101

Title: Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.

Journal: International journal of molecular sciences 20110101

Title: Predicting biological functions of compounds based on chemical-chemical interactions.

Journal: PloS one 20110101

Title: Synthesis of chitin cycloalkyl ester derivatives and their physical properties.

Journal: Carbohydrate research 20100923

Title: The 5' untranslated region of the VR-ACS1 mRNA acts as a strong translational enhancer in plants.

Journal: Transgenic research 20100801

Title: Chiral alpha-aminoxy acid/achiral cyclopropane alpha-aminoxy acid unit as a building block for constructing the alpha N-O helix.

Journal: The Journal of organic chemistry 20100716

Title: Ethylene is involved in nitrate-dependent root growth and branching in Arabidopsis thaliana.

Journal: The New phytologist 20091201

Title: Synthesis and SAR of 2-phenyl-1-sulfonylaminocyclopropane carboxylates as ADAMTS-5 (Aggrecanase-2) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20091101

Title: The synthesis and photoactivated cytotoxicity of 2-methyl-4-oxo-3-prop-2-yn-1-ylcyclopent-2-en-1-yl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate conjugated with alpha-terthienyl derivatives.

Journal: Journal of photochemistry and photobiology. B, Biology 20090904

Title: (E)-2-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-N-(2,4-dimethyl-phen-yl)-3,3-dimethyl-cyclo-propane-1-carboxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: The discovery of novel calcium sensing receptor negative allosteric modulators.

Journal: Bioorganic & medicinal chemistry letters 20090615

Title: Identification, characterization and utilization of unigene derived microsatellite markers in tea (Camellia sinensis L.).

Journal: BMC plant biology 20090101

Title: A convenient chemo-enzymatic synthesis and 18F-labelling of both enantiomers of trans-1-toluenesulfonyloxymethyl-2-fluoromethyl-cyclopropane.

Journal: Organic & biomolecular chemistry 20081221

Title: Potential energy scans and vibrational assignments of cyclopropanecarboxylic acid and cyclopropanecarboxamide.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081215

Title: Tandem cyclopropanation with dibromomethane under Grignard conditions.

Journal: The Journal of organic chemistry 20081003

Title: Nucleophilic addition of phenol derivatives to methyl 1-nitrocyclopropanecarboxylates.

Journal: The Journal of organic chemistry 20080905

Title: Direct quantitation of fatty acids present in bacteria and fungi: stability of the cyclopropane ring to chlorotrimethylsilane.

Journal: Journal of agricultural and food chemistry 20080709

Title: A new sigma ligand, (+/-)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect.

Journal: Life sciences 20080312

Title: Cyclopropanecarboxylic acid esters as potential prodrugs with enhanced hydrolytic stability.

Journal: Organic letters 20080207

Title: Practical, general, and systematic method for optical resolution of gem-dihalo- and monohalocyclopropanecarboxylic acids utilizing chiral 1,1'-binaphtholmonomethyl ethers: application to the synthesis of three chiral pesticides.

Journal: Organic & biomolecular chemistry 20080207

Title: A general stereoselective method for the synthesis of cyclopropanecarboxylates. A new version of the homologous Horner-Wadsworth-Emmons reaction.

Journal: Organic & biomolecular chemistry 20080121

Title: trans-(1R,2R)-1-benzyl-2-phenylcyclopropanecarboxylic acid.

Journal: Acta crystallographica. Section C, Crystal structure communications 20080101

Title: (E)-3-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-2,2-dimethyl-N,N-diphenyl-cyclo-propane-carboxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Enantioseparation and determination of 2,2-dimethylcyclopropanecarboxamide and corresponding acid in the bioconversion broth by gas chromatography.

Journal: Biomedical chromatography : BMC 20070601

Title: Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles.

Journal: Toxicologic pathology 20070601

Title: Reaction pathways of the diketonitrile degradate of isoxaflutole with hypochlorite in water.

Journal: Journal of agricultural and food chemistry 20070307

Title: Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070201

Title: Enzyme inhibition potency enhancement by active site metal chelating and hydrogen bonding induced conformation-restricted cyclopropanecarbonyl derivatives.

Journal: Bioorganic & medicinal chemistry letters 20061201

Title: Enantiomeric differences in permethrin degradation pathways in soil and sediment.

Journal: Journal of agricultural and food chemistry 20061129

Title: Towards selective antagonists of T-type calcium channels: design, characterization and potential applications of NNC 55-0396.

Journal: Cardiovascular drug reviews 20050101

Title: Synthetic approach to substituted cyclopropanes based on the coupling reaction of lithiated chloroalkyloxazolines with Fischer carbene complexes.

Journal: The Journal of organic chemistry 20040806

Title: Novel pathway for utilization of cyclopropanecarboxylate by Rhodococcus rhodochrous.

Journal: Applied and environmental microbiology 20040101

Title: Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression.

Journal: Toxicologic pathology 20040101

Title: Delftia tsuruhatensis sp. nov., a terephthalate-assimilating bacterium isolated from activated sludge.

Journal: International journal of systematic and evolutionary microbiology 20030901

Title: Stereocontrolled synthesis of 3-(trans-2-aminocyclopropyl)alanine, a key component of belactosin A.

Journal: Organic letters 20030626

Title: Synthesis and insecticidal activity of novel N-oxydihydropyrrole derivatives with a substituted spirocyclohexyl group.

Journal: Bioscience, biotechnology, and biochemistry 20030601

Title: Nitrile biotransformation for highly enantioselective synthesis of 3-substituted 2,2-dimethylcyclopropanecarboxylic acids and amides.

Journal: The Journal of organic chemistry 20030124

Title: Development of a DNA microarray for toxicology based on hepatotoxin-regulated sequences.

Journal: EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences 20030101

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