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176-80-7,MFCD01665114
Catalog No.:AA0021A7

176-80-7 | 1-Azaspiro[4.5]decane

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$361.00   $253.00
- +
1g
97%
in stock  
$885.00   $619.00
- +
5g
97%
in stock  
$2,632.00 $1,843.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0021A7
Chemical Name:
1-Azaspiro[4.5]decane
CAS Number:
176-80-7
Molecular Formula:
C9H17N
Molecular Weight:
139.2380
MDL Number:
MFCD01665114
SMILES:
C1CCC2(CC1)CCCN2
NSC Number:
19984
Properties
Computed Properties
 
Complexity:
114  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
0  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.9  

Downstream Synthesis Route
176-80-7    75-15-0   
1-aza-spiro4.5decane-1-carbodithioicacid 

[1]Terent'ewetal.[Chemija,1959,p.129,132][Chem.Abstr.,1960,p.527]

176-80-7    86-84-0   
1-aza-spiro4.5decane-1-carboxylicacid-1naphthylamide 

[1]Kostetal.[VestnikMoskovskogoUniversiteta,1954,vol.9,#9,p.115,117][Chem.Abstr.,1955,p.15856]

[1]Moffett[JournaloftheAmericanChemicalSociety,1957,vol.79,p.3186,3190]

[1]Moffett[JournaloftheAmericanChemicalSociety,1957,vol.79,p.3186,3190]

[1]Mimura;Hayashida;Nomiyama;Ikegami;Iida;Tamura;Hiyama;Ohishi[ChemicalandPharmaceuticalBulletin,1993,vol.41,#11,p.1971-1986]

[2]Bryce,MartinR.;Gardiner,JohnM.;Horton,PaulJ.;Smith,SusanA.[JournalofChemicalResearch,Miniprint,1989,#1,p.116-124]

[3]Ma,Xiaofeng;Lubin,Hodney;Ioja,Eniko;Kékesi,Orsolya;Simon,Ágnes;Apáti,Ágota;Orbán,TamásI.;Héja,László;Kardos,Julianna;Markó,IstvánE.[BioorganicandMedicinalChemistryLetters,2016,vol.26,#2,p.417-423]

[4]Moffett[JournaloftheAmericanChemicalSociety,1957,vol.79,p.3186,3190]

Literature

Title: Coinage metals-catalyzed cascade reactions of aryl alkynylaziridines: silver(I)-single vs gold(I)-double cyclizations.

Journal: The Journal of organic chemistry 20120504

Title: Ring-rearrangement metathesis of 1-substituted 7-azanorbornenes as an entry to 1-azaspiro[4.5]decane systems.

Journal: The Journal of organic chemistry 20110506

Title: Total synthesis of the tricyclic marine alkaloids (-)-lepadiformine, (+)-cylindricine c, and (-)-fasicularin via a common intermediate formed by formic acid-induced intramolecular conjugate azaspirocyclization.

Journal: Journal of the American Chemical Society 20050209

Title: Functionalized spiro- and fused-ring heterocycles via oxidative demetalation of cyclohexadienyl ruthenium complexes.

Journal: The Journal of organic chemistry 20040220

Title: Intramolecular cyclization with nitrenium ions generated by treatment of N-acylaminophthalimides with hypervalent iodine compounds: formation of lactams and spiro-fused lactams.

Journal: The Journal of organic chemistry 20030822

Title: Synthesis of spirodienones by intramolecular ipso-cyclization of N-methoxy-(4-halogenophenyl)amides using [hydroxy(tosyloxy)iodo]benzene in trifluoroethanol.

Journal: The Journal of organic chemistry 20030627

Title: Oxidative demetalation of cyclohexadienyl ruthenium(II) complexes: a net Ru-mediated dearomatization.

Journal: Organic letters 20030529

Title: N-methoxy-N-acylnitrenium ions: application to the formal synthesis of (-)-TAN1251A.

Journal: Organic letters 20010405

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SDS
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Tags:176-80-7 Molecular Formula|176-80-7 MDL|176-80-7 SMILES|176-80-7 1-Azaspiro[4.5]decane
Catalog No.: AA0021A7
176-80-7,MFCD01665114
176-80-7 | 1-Azaspiro[4.5]decane
Pack Size： 250mg
Purity： 97%
in stock
$361.00 $253.00
Pack Size： 1g
Purity： 97%
in stock
$885.00 $619.00
Pack Size： 5g
Purity： 97%
in stock
$2,632.00 $1,843.00
Quantity
- +
Add to Card
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Technical Information
Catalog Number: AA0021A7
Chemical Name: 1-Azaspiro[4.5]decane
CAS Number: 176-80-7
Molecular Formula: C9H17N
Molecular Weight: 139.2380
MDL Number: MFCD01665114
SMILES: C1CCC2(CC1)CCCN2
NSC Number: 19984
Properties
Complexity: 114  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 10  
Hydrogen Bond Acceptor Count: 1  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 0  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.9  
Downstream Synthesis Route
176-80-7    75-15-0   
1-aza-spiro4.5decane-1-carbodithioicacid 

[1]Terent'ewetal.[Chemija,1959,p.129,132][Chem.Abstr.,1960,p.527]

176-80-7    86-84-0   
1-aza-spiro4.5decane-1-carboxylicacid-1naphthylamide 

[1]Kostetal.[VestnikMoskovskogoUniversiteta,1954,vol.9,#9,p.115,117][Chem.Abstr.,1955,p.15856]

176-80-7    627-30-5    108322-27-6 

[1]Moffett[JournaloftheAmericanChemicalSociety,1957,vol.79,p.3186,3190]

176-80-7    107-07-3    100049-37-4 

[1]Moffett[JournaloftheAmericanChemicalSociety,1957,vol.79,p.3186,3190]

5498-74-8    176-80-7 

[1]Mimura;Hayashida;Nomiyama;Ikegami;Iida;Tamura;Hiyama;Ohishi[ChemicalandPharmaceuticalBulletin,1993,vol.41,#11,p.1971-1986]

[2]Bryce,MartinR.;Gardiner,JohnM.;Horton,PaulJ.;Smith,SusanA.[JournalofChemicalResearch,Miniprint,1989,#1,p.116-124]

[3]Ma,Xiaofeng;Lubin,Hodney;Ioja,Eniko;Kékesi,Orsolya;Simon,Ágnes;Apáti,Ágota;Orbán,TamásI.;Héja,László;Kardos,Julianna;Markó,IstvánE.[BioorganicandMedicinalChemistryLetters,2016,vol.26,#2,p.417-423]

[4]Moffett[JournaloftheAmericanChemicalSociety,1957,vol.79,p.3186,3190]

Literature fold

Title: Coinage metals-catalyzed cascade reactions of aryl alkynylaziridines: silver(I)-single vs gold(I)-double cyclizations.

Journal: The Journal of organic chemistry20120504

Title: Ring-rearrangement metathesis of 1-substituted 7-azanorbornenes as an entry to 1-azaspiro[4.5]decane systems.

Journal: The Journal of organic chemistry20110506

Title: Total synthesis of the tricyclic marine alkaloids (-)-lepadiformine, (+)-cylindricine c, and (-)-fasicularin via a common intermediate formed by formic acid-induced intramolecular conjugate azaspirocyclization.

Journal: Journal of the American Chemical Society20050209

Title: Functionalized spiro- and fused-ring heterocycles via oxidative demetalation of cyclohexadienyl ruthenium complexes.

Journal: The Journal of organic chemistry20040220

Title: Intramolecular cyclization with nitrenium ions generated by treatment of N-acylaminophthalimides with hypervalent iodine compounds: formation of lactams and spiro-fused lactams.

Journal: The Journal of organic chemistry20030822

Title: Synthesis of spirodienones by intramolecular ipso-cyclization of N-methoxy-(4-halogenophenyl)amides using [hydroxy(tosyloxy)iodo]benzene in trifluoroethanol.

Journal: The Journal of organic chemistry20030627

Title: Oxidative demetalation of cyclohexadienyl ruthenium(II) complexes: a net Ru-mediated dearomatization.

Journal: Organic letters20030529

Title: N-methoxy-N-acylnitrenium ions: application to the formal synthesis of (-)-TAN1251A.

Journal: Organic letters20010405

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