1777-82-8,MFCD00004606
Catalog No.:AA0025E9

1777-82-8 | 2,4-Dichlorobenzyl alcohol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
98%
in stock  
$6.00   $4.00
- +
25g
98%
in stock  
$12.00   $8.00
- +
100g
≥98%
in stock  
$38.00   $27.00
- +
500g
98%
in stock  
$156.00   $109.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0025E9
Chemical Name:
2,4-Dichlorobenzyl alcohol
CAS Number:
1777-82-8
Molecular Formula:
C7H6Cl2O
Molecular Weight:
177.0279
MDL Number:
MFCD00004606
SMILES:
OCc1ccc(cc1Cl)Cl
NSC Number:
15635
Properties
Properties
 
BP:
268.4°C at 760 mmHg  
Form:
Solid  
MP:
55-58°C  
Refractive Index:
1.5756 (estimate)  
Solubility:
1g/l  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
108  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.5  

Upstream Synthesis Route

[1]Patent:CN106117028,2016,A,.Locationinpatent:Paragraph0053;0054;0055;0056

[1]TetrahedronLetters,2014,vol.55,#1,p.90-93

[2]Patent:CN106117028,2016,A,.Locationinpatent:Paragraph0057;0058

[3]OrganicProcessResearchandDevelopment,2002,vol.6,#2,p.190-191

[4]MonatsheftefurChemie,2004,vol.135,#10,p.1251-1255

[5]JournalofMedicinalChemistry,1989,vol.32,#8,p.1757-1763

[6]JournalofMedicinalChemistry,1996,vol.39,#18,p.3569-3584

[7]ScientiaPharmaceutica,2001,vol.69,#4,p.329-350

[1]OrganicandBiomolecularChemistry,2018,vol.16,#23,p.4288-4294

[1]ScientiaPharmaceutica,2001,vol.69,#4,p.329-350

[2]Patent:CN106117028,2016,A,

[1]ScientiaPharmaceutica,2001,vol.69,#4,p.329-350

[2]Patent:CN106117028,2016,A,

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartKouhkan,Mehri;Zeynizadeh,Behzad[BulletinoftheKoreanChemicalSociety,2010,vol.31,#10,p.2961-2966]

[2]Setamdideh,Davood;Zeynizadeh,Behzad[ZeitschriftfurNaturforschung,B:ChemicalSciences,2006,vol.61,#10,p.1275-1281]

[3]Xue,Benjing;Sun,Hongjian;Li,Xiaoyan[RSCAdvances,2015,vol.5,#64,p.52000-52006]

[4]Wang,Yangyang;Du,Zhengyin;Zheng,Tingting;Sun,Hongjian;Li,Xiaoyan[CatalysisCommunications,2019,vol.124,p.32-35]

[5]Locationinpatent:experimentalpartSetamdideh,Davood;Ghahremani,Sahar[SouthAfricanJournalofChemistry,2012,vol.65,p.91-97]

[6]Locationinpatent:experimentalpartSetamdideh,Davood;Khezri,Behrooz;Rahmatollahzadeh,Mehdi;Poramjad,AvatAli[AsianJournalofChemistry,2012,vol.24,#8,p.3591-3596]

[7]Setamdideh,Davood;Khaledi,Leila[SouthAfricanJournalofChemistry,2013,vol.66,p.150-157]

[8]Setamdideh,Davood;Karimi,Zahra;Alipouramjad,Avat[JournaloftheChineseChemicalSociety,2013,vol.60,#6,p.590-596]

[9]Abdollahpour,Fatemeh;Setamdideh,Davood[OrientalJournalofChemistry,2015,vol.31,#3,p.1787-1792]

[10]Mohammadi,Sina;Setamdideh,Davood[OrientalJournalofChemistry,2015,vol.31,#4,p.2395-2399]

[11]Xue,Benjing;Sun,Hongjian;Niu,Qingfen;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[CatalysisCommunications,2017,vol.94,p.23-28]

[12]Halimjani,AzimZiyaei;Saidi,MohammadR.[SyntheticCommunications,2005,vol.35,#17,p.2271-2276]

[13]Zeynizadeh,Behzad;Kouhkan,Mehri[JournaloftheChineseChemicalSociety,2018,vol.65,#12,p.1521-1528]

[14]Setamdideh,Davood;Khezri,Behrooz;Rahmatollahzadeh,Mehdi[JournaloftheSerbianChemicalSociety,2013,vol.78,#1,p.1-13]

[15]Zhao,Hua;Sun,Hongjian;Li,Xiaoyan[Organometallics,2014,vol.33,#13,p.3535-3539]

[16]Aboo,AhmedH.;Bennett,ElliotL.;Deeprose,Mark;Robertson,CraigM.;Iggo,JonathanA.;Xiao,Jianliang[ChemicalCommunications,2018,vol.54,#83,p.11805-11808]

[17]Khurana,JitenderM.;Bansal,Geeti;Kukreja,Gagan;Pandey,RaviR.[MonatsheftefurChemie,2003,vol.134,#10,p.1365-1371]

[18]Chang,Guoliang;Fenske,Dieter;Fuhr,Olaf;Li,Xiaoyan;Sun,Hongjian;Xie,Shangqing;Yang,Wenjing;Zhang,Peng[DaltonTransactions,2020,vol.49,#27,p.9349-9354]

[19]Wang,Lin;Sun,Hongjian;Li,Xiaoyan[Organometallics,2015,vol.34,#20,p.5175-5182]

[20]Saharan,Ritu[JournaloftheIndianChemicalSociety,2022,vol.99,#3]

[21]Zhang,Peng;Li,Xiaoyan;Qi,Xinghao;Sun,Hongjian;Fuhr,Olaf;Fenske,Dieter[RSCAdvances,2018,vol.8,#25,p.14092-14099]

[22]Khurana;Chauhan[SyntheticCommunications,2001,vol.31,#22,p.3485-3489]

[23]Lau,CheukK.;Tardif,Sylvie;Dufresne,Claude;Scheigetz,John[JournalofOrganicChemistry,1989,vol.54,#2,p.491-494]

[24]Locationinpatent:experimentalpartKumar,K.Anil;Gowda,D.Channe[E-JournalofChemistry,2011,vol.8,#1,p.49-52]

[25]Wei,Yawen;Xue,Dong;Lei,Qian;Wang,Chao;Xiao,Jianliang[GreenChemistry,2013,vol.15,#3,p.629-634]

[26]Kuroda,Kazunori;Nagamatsu,Tomohisa;Yanada,Reiko;Yoneda,Fumio[JournaloftheChemicalSociety.PerkintransactionsI,1993,#5,p.547-550]

[27]Kim,BokTae;Cho,ChanSik;Kim,Tae-Jeong;Shim,SangChul[JournalofChemicalResearch-PartS,2003,#6,p.368-369]

[28]Demmel,GabrielI.;Bordón,DanielaL.;Vázquez,AnaM.;Decarlini,MaríaF.;DíazPanero,Mariángeles;Rossi,LauraI.;Aimar,MarioL.[BiocatalysisandBiotransformation,2023,vol.41,#2,p.93-107]

[29]Metayer;Dat-Xuong[BulletindelaSocieteChimiquedeFrance,1954,p.615,617]

[30]Hook,IngridL.;Ryan,Shane;Sheridan,Helen[Phytochemistry,1999,vol.51,#5,p.621-627]

[31]He,Chao;Zhang,Xiaohui;Huang,Ruofeng;Pan,Jing;Li,Jiaqiang;Ling,Xuege;Xiong,Yan;Zhu,Xiangming[TetrahedronLetters,2014,vol.55,#32,p.4458-4462]

[32]Wang,Lin;Sun,Hongjian;Li,Xiaoyan[EuropeanJournalofInorganicChemistry,2015,vol.2015,#16,p.2732-2743]

[33]Zheng,Tingting;Li,Junye;Zhang,Shumiao;Xue,Benjing;Sun,Hongjian;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[Organometallics,2016,vol.35,#20,p.3538-3545]

[34]Christie,Francesca;Zanotti-Gerosa,Antonio;Grainger,Damian[ChemCatChem,2018,vol.10,#5,p.1012-1018]

[35]Nath,Utpal;Chowdhury,Deepan;Pan,SubhasChandra[AdvancedSynthesisandCatalysis,2018,vol.360,#8,p.1628-1633]

[36]Wang,Yangyang;Ren,Shishuai;Zhang,Wenbo;Xue,Benjing;Qi,Xinghao;Sun,Hongjian;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[CatalysisCommunications,2018,vol.115,p.1-5]

[37]Yang,Jin;Yuan,Man;Xu,Dan;Zhao,Hong;Zhu,Yangyang;Fan,Menying;Zhang,Fengwei;Dong,Zhengping[JournalofMaterialsChemistryA,2018,vol.6,#37,p.18242-18251]

[38]Qi,Xinghao;Zhao,Hua;Sun,Hongjian;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[NewJournalofChemistry,2018,vol.42,#20,p.16583-16590]

[39]Qi,Xinghao;Zheng,Tingting;Zhou,Junhao;Dong,Yanhong;Zuo,Xia;Li,Xiaoyan;Sun,Hongjian;Fuhr,Olaf;Fenske,Dieter[Organometallics,2019,vol.38,#2,p.268-277]

[40]Du,Xinyu;Qi,Xinghao;Li,Kai;Li,Xiaoyan;Sun,Hongjian;Fuhr,Olaf;Fenske,Dieter[AppliedOrganometallicChemistry,2021,vol.35,#8]

[41]Battu,Satyanarayana;Joolakanti,HimaBindhu;Kamepalli,Ramanjaneyulu;Miryala,Jeevanreddy[JournalofMolecularStructure,2021,vol.1242]

[42]Fan,Qingqing;Du,Xinyu;Yang,Wenjing;Li,Qingshuang;Huang,Wei;Sun,Hongjian;Hinz,Alexander;Li,Xiaoyan[DaltonTransactions,2023,vol.52,#20,p.6712-6721]

[1]vandeLande[RecueildesTravauxChimiquesdesPays-Bas,1932,vol.51,p.98,109]

[2]vandeLande[RecueildesTravauxChimiquesdesPays-Bas,1932,vol.51,p.98,109]

[3]Zhao,Qiangqiang;Sun,Jie;Liu,Baojiang;He,Jinxin[DyesandPigments,2013,vol.99,#2,p.339-347]

[1]Patent:CN106117028,2016,A.Locationinpatent:Paragraph0047;0048;0049;0050;0051;0052

[2]JournaloftheAmericanChemicalSociety,1973,vol.95,p.3757-3763

[3]Synlett,1997,vol.1997,p.989-991

[4]ChemicalCommunications,2019,vol.55,p.1386-1389

[1]AppliedOrganometallicChemistry,2020

[2]RSCAdvances,2016,vol.6,p.63717-63723

[3]JournalofMaterialsChemistryA,2016,vol.4,p.3933-3946

[4]JournalofPhotochemistryandPhotobiologyA:Chemistry,2020,vol.389

[5]Synthesis,2006,p.2043-2046

[6]ResearchonChemicalIntermediates,2013,vol.39,p.3337-3343

[7]JournaloftheChineseChemicalSociety,2014,vol.61,p.1039-1044

[8]JournaloftheChineseChemicalSociety,2007,vol.54,p.1257-1260

[9]JournaloftheChineseChemicalSociety,2007,vol.54,p.1257-1260

[10]JournaloftheIranianChemicalSociety,2011,vol.8,p.1082-1090

[11]AppliedOrganometallicChemistry,2018,vol.32

[12]JournaloftheAmericanChemicalSociety,2009,vol.131,p.251-262

[13]ChemicalCommunications,2013,vol.49,p.7908-7910

[14]SyntheticCommunications,2015,vol.45,p.1334-1341

[15]RSCAdvances,2015,vol.5,p.70577-70585

[16]RSCAdvances,2016,vol.6,p.51347-51355

[17]MendeleevCommunications,2005,vol.15,p.113-116

[18]Tetrahedron,2015,vol.71,p.8725-8731

[19]ChineseChemicalLetters,2012,vol.23,p.21-24

[20]JournaloftheIranianChemicalSociety,2016,vol.13,p.1963-1975

[21]AppliedOrganometallicChemistry,2018,vol.32

[22]JournaloftheChineseChemicalSociety,2007,vol.54,p.465-468

[23]AppliedOrganometallicChemistry,2016,vol.30,p.577-580

[24]Patent:CN107400050,2017,A.Locationinpatent:Paragraph0005;0015;0017;0018;0020

[25]Organicandbiomolecularchemistry,2020,vol.18,p.2326-2330

[26]AppliedOrganometallicChemistry,2017,vol.31

[27]AppliedOrganometallicChemistry,2017,vol.31

[28]TetrahedronLetters,2005,vol.46,p.8483-8486

[29]JournalofChemicalResearch,2006,p.188-191

[30]TetrahedronLetters,2006,vol.47,p.8953-8957

[31]GreenChemistry,2012,vol.14,p.1493-1501

[32]TransitionMetalChemistry,2018,vol.43,p.579-589

[33]PolishJournalofChemistry,2004,vol.78,p.741-744

[34]CatalysisLetters,2018,vol.148,p.1110-1123

[35]BioorganicandMedicinalChemistry,2005,vol.13,p.2901-2905

[36]TransitionMetalChemistry,2016,vol.41,p.767-774

[37]CatalysisCommunications,2019,vol.124,p.76-80

[38]JournalofPhotochemistryandPhotobiologyA:Chemistry,2019,vol.371,p.173-181

[39]SouthAfricanJournalofChemistry,2007,vol.60,p.58-61

[40]JournalofChemicalSciences,2015,vol.127,p.1321-1328

[41]JournalofChemicalResearch,2007,p.252-256

[42]ChemPlusChem,2014,vol.79,p.217-222

[43]JournalofOrganicChemistry,2017,vol.82,p.7165-7175

[44]CatalysisLetters,2014,vol.144,p.355-363

[45]CatalysisCommunications,2016,vol.77,p.9-12

[46]CatalysisCommunications,2017,vol.101,p.98-101

[47]PolishJournalofChemistry,2006,vol.80,p.1377-1383

[48]RSCAdvances,2014,vol.4,p.49974-49978

[49]RSCAdvances,2014,vol.4,p.34681-34686

[50]EuropeanJournalofInorganicChemistry,2020,vol.2020,p.480-490

[51]ActachemicaScandinavica.SeriesB:Organicchemistryandbiochemistry,1983,vol.37,p.499-508

[52]TetrahedronLetters,1999,vol.40,p.3723-3726

[53]ZeitschriftfurNaturforschung,B:ChemicalSciences,2007,vol.62,p.537-539

[54]ZeitschriftfurNaturforschung,B:ChemicalSciences,2006,vol.61,p.326-330

[55]ZeitschriftfurNaturforschung,B:ChemicalSciences,2006,vol.61,p.326-330

[56]SouthAfricanJournalofChemistry,2008,vol.61,p.9-12

[57]ChemicalCommunications,2009,p.5555-5557

[58]GreenChemistry,2011,vol.13,p.991-997

[59]OrganicandBiomolecularChemistry,2011,vol.9,p.4194-4198

[60]Chemistry-AEuropeanJournal,2011,vol.17,p.6056-6060

[61]AsianJournalofChemistry,2011,vol.23,p.829-831

[62]AdvancedSynthesisandCatalysis,2012,vol.354,p.1319-1326

[63]Chemistry-AEuropeanJournal,2012,vol.18,p.8634-8640

[64]TetrahedronLetters,2012,vol.53,p.4962-4965

[65]Chemistry-AEuropeanJournal,2012,vol.18,p.13520-13530

[66]Polyhedron,2012,vol.47,p.94-103

[67]ComptesRendusChimie,2013,vol.16,p.109-113

[68]DaltonTransactions,2013,vol.42,p.6829-6839

[69]RSCAdvances,2013,vol.3,p.19255-19258

[70]ChineseJournalofChemistry,2014,vol.32,p.117-122

[71]JournalofMolecularCatalysisA:Chemical,2014,vol.392,p.8-15

[72]SyntheticCommunications,2014,vol.44,p.2818-2825

[73]EuropeanJournalofInorganicChemistry,2014,vol.2014,p.6066-6074

[74]AppliedOrganometallicChemistry,2015,vol.29,p.561-565

[75]Polyhedron,2015,vol.99,p.260-265

[76]Polyhedron,2016,vol.106,p.153-162

[77]JournaloftheIranianChemicalSociety,2016,vol.13,p.1463-1470

[78]ChemPlusChem,2016,vol.81,p.1160-1165

[79]ChemSusChem,2014,vol.7,p.2735-2741

[80]ChemistryOpen,2017,vol.6,p.112-120

[81]JournaloftheIranianChemicalSociety,2017,vol.14,p.1317-1323

[82]JournalofChemistry,2017,vol.2017

[83]NewJournalofChemistry,2017,vol.41,p.3405-3413

[84]RSCAdvances,2018,vol.8,p.6768-6780

[85]JournaloftheIranianChemicalSociety,2018,vol.15,p.893-904

[86]RSCAdvances,2017,vol.7,p.55336-55349

[87]ChemCatChem,2018,vol.10,p.1542-1546

[88]AppliedCatalysisA:General,2018,vol.563,p.185-195

[89]Polymer,2018,vol.149,p.229-237

[90]AppliedOrganometallicChemistry,2018,vol.32

[91]OrganicProcessResearchandDevelopment,2018,vol.22,p.1298-1305

[92]JournaloftheIranianChemicalSociety,2019,vol.16,p.563-570

[93]Molecularcatalysis,2019,vol.468,p.75-79

[94]CatalysisLetters,2019,vol.149,p.1237-1249

[95]AppliedOrganometallicChemistry,2020,vol.34

[96]NewJournalofChemistry,2020,vol.44,p.4426-4439

[97]AppliedOrganometallicChemistry,2020,vol.34

[98]ACSCombinatorialScience,2020,vol.22,p.70-79

[99]JournaloftheIranianChemicalSociety,2020

[1]TetrahedronLetters,2014,vol.55,p.90-93

[2]Patent:CN106117028,2016,A.Locationinpatent:Paragraph0057;0058

[3]OrganicProcessResearchandDevelopment,2002,vol.6,p.190-191

[4]MonatsheftefurChemie,2004,vol.135,p.1251-1255

[5]JournalofMedicinalChemistry,1989,vol.32,p.1757-1763

[6]JournalofMedicinalChemistry,1996,vol.39,p.3569-3584

[7]ScientiaPharmaceutica,2001,vol.69,p.329-350

[8]Chemistry-AEuropeanJournal,2019,vol.25,p.6290-6294

Literature

Title: Randomised, double-blind, placebo-controlled study of a single dose of an amylmetacresol/2,4-dichlorobenzyl alcohol plus lidocaine lozenge or a hexylresorcinol lozenge for the treatment of acute sore throat due to upper respiratory tract infection.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101

Title: Acute sore throat revisited: clinical and experimental evidence for the efficacy of over-the-counter AMC/DCBA throat lozenges.

Journal: International journal of clinical practice 20110501

Title: A multicentre, randomised, double-blind, single-dose study assessing the efficacy of AMC/DCBA Warm lozenge or AMC/DCBA Cool lozenge in the relief of acute sore throat.

Journal: BMC family practice 20110101

Title: Rapid relief of acute sore throat with AMC/DCBA throat lozenges: randomised controlled trial.

Journal: International journal of clinical practice 20100101

Title: Topical antiseptics for the treatment of sore throat block voltage-gated neuronal sodium channels in a local anaesthetic-like manner.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090801

Title: Allergic contact dermatitis from dichlorobenzyl alcohol in a patient with multiple contact allergies.

Journal: Contact dermatitis 20090501

Title: FT-Raman and FT-IR spectra, ab initio and density functional studies of 3,4-dichlorobenzyl alcohol.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061101

Title: A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV.

Journal: Antiviral chemistry & chemotherapy 20050101

Title: Efficacy of three surface disinfectants for dental radiographic films and gloves.

Journal: Journal of dentistry 20040701

Title: Morokutti-Kurz M , et al. Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat. Int J Gen Med. 2017 Feb 28;10:53-60.

Title: Matthews D, et al. Spectrum of bactericidal action of amylmetacresol/2,4-dichlorobenzyl alcohol lozenges against oropharyngeal organisms implicated in pharyngitis. Int J Gen Med. 2018 Nov 28;11:451-456.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:1777-82-8 Molecular Formula|1777-82-8 MDL|1777-82-8 SMILES|1777-82-8 2,4-Dichlorobenzyl alcohol
Catalog No.: AA0025E9
1777-82-8,MFCD00004606
1777-82-8 | 2,4-Dichlorobenzyl alcohol
Pack Size: 5g
Purity: 98%
in stock
$6.00 $4.00
Pack Size: 25g
Purity: 98%
in stock
$12.00 $8.00
Pack Size: 100g
Purity: ≥98%
in stock
$38.00 $27.00
Pack Size: 500g
Purity: 98%
in stock
$156.00 $109.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0025E9
Chemical Name: 2,4-Dichlorobenzyl alcohol
CAS Number: 1777-82-8
Molecular Formula: C7H6Cl2O
Molecular Weight: 177.0279
MDL Number: MFCD00004606
SMILES: OCc1ccc(cc1Cl)Cl
NSC Number: 15635
Properties
BP: 268.4°C at 760 mmHg  
Form: Solid  
MP: 55-58°C  
Refractive Index: 1.5756 (estimate)  
Solubility: 1g/l  
Storage: Room Temperature;  
Complexity: 108  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 10  
Hydrogen Bond Acceptor Count: 1  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.5  
Upstream Synthesis Route
1777-82-8    94-99-5 

[1]Patent:CN106117028,2016,A,.Locationinpatent:Paragraph0053;0054;0055;0056

1777-82-8    20443-99-6 

[1]TetrahedronLetters,2014,vol.55,#1,p.90-93

[2]Patent:CN106117028,2016,A,.Locationinpatent:Paragraph0057;0058

[3]OrganicProcessResearchandDevelopment,2002,vol.6,#2,p.190-191

[4]MonatsheftefurChemie,2004,vol.135,#10,p.1251-1255

[5]JournalofMedicinalChemistry,1989,vol.32,#8,p.1757-1763

[6]JournalofMedicinalChemistry,1996,vol.39,#18,p.3569-3584

[7]ScientiaPharmaceutica,2001,vol.69,#4,p.329-350

1777-82-8    22916-47-8 

[1]OrganicandBiomolecularChemistry,2018,vol.16,#23,p.4288-4294

1777-82-8    19719-28-9 

[1]ScientiaPharmaceutica,2001,vol.69,#4,p.329-350

[2]Patent:CN106117028,2016,A,

1777-82-8    6306-60-1 

[1]ScientiaPharmaceutica,2001,vol.69,#4,p.329-350

[2]Patent:CN106117028,2016,A,

Downstream Synthesis Route
874-42-0    1777-82-8 

[1]Locationinpatent:experimentalpartKouhkan,Mehri;Zeynizadeh,Behzad[BulletinoftheKoreanChemicalSociety,2010,vol.31,#10,p.2961-2966]

[2]Setamdideh,Davood;Zeynizadeh,Behzad[ZeitschriftfurNaturforschung,B:ChemicalSciences,2006,vol.61,#10,p.1275-1281]

[3]Xue,Benjing;Sun,Hongjian;Li,Xiaoyan[RSCAdvances,2015,vol.5,#64,p.52000-52006]

[4]Wang,Yangyang;Du,Zhengyin;Zheng,Tingting;Sun,Hongjian;Li,Xiaoyan[CatalysisCommunications,2019,vol.124,p.32-35]

[5]Locationinpatent:experimentalpartSetamdideh,Davood;Ghahremani,Sahar[SouthAfricanJournalofChemistry,2012,vol.65,p.91-97]

[6]Locationinpatent:experimentalpartSetamdideh,Davood;Khezri,Behrooz;Rahmatollahzadeh,Mehdi;Poramjad,AvatAli[AsianJournalofChemistry,2012,vol.24,#8,p.3591-3596]

[7]Setamdideh,Davood;Khaledi,Leila[SouthAfricanJournalofChemistry,2013,vol.66,p.150-157]

[8]Setamdideh,Davood;Karimi,Zahra;Alipouramjad,Avat[JournaloftheChineseChemicalSociety,2013,vol.60,#6,p.590-596]

[9]Abdollahpour,Fatemeh;Setamdideh,Davood[OrientalJournalofChemistry,2015,vol.31,#3,p.1787-1792]

[10]Mohammadi,Sina;Setamdideh,Davood[OrientalJournalofChemistry,2015,vol.31,#4,p.2395-2399]

[11]Xue,Benjing;Sun,Hongjian;Niu,Qingfen;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[CatalysisCommunications,2017,vol.94,p.23-28]

[12]Halimjani,AzimZiyaei;Saidi,MohammadR.[SyntheticCommunications,2005,vol.35,#17,p.2271-2276]

[13]Zeynizadeh,Behzad;Kouhkan,Mehri[JournaloftheChineseChemicalSociety,2018,vol.65,#12,p.1521-1528]

[14]Setamdideh,Davood;Khezri,Behrooz;Rahmatollahzadeh,Mehdi[JournaloftheSerbianChemicalSociety,2013,vol.78,#1,p.1-13]

[15]Zhao,Hua;Sun,Hongjian;Li,Xiaoyan[Organometallics,2014,vol.33,#13,p.3535-3539]

[16]Aboo,AhmedH.;Bennett,ElliotL.;Deeprose,Mark;Robertson,CraigM.;Iggo,JonathanA.;Xiao,Jianliang[ChemicalCommunications,2018,vol.54,#83,p.11805-11808]

[17]Khurana,JitenderM.;Bansal,Geeti;Kukreja,Gagan;Pandey,RaviR.[MonatsheftefurChemie,2003,vol.134,#10,p.1365-1371]

[18]Chang,Guoliang;Fenske,Dieter;Fuhr,Olaf;Li,Xiaoyan;Sun,Hongjian;Xie,Shangqing;Yang,Wenjing;Zhang,Peng[DaltonTransactions,2020,vol.49,#27,p.9349-9354]

[19]Wang,Lin;Sun,Hongjian;Li,Xiaoyan[Organometallics,2015,vol.34,#20,p.5175-5182]

[20]Saharan,Ritu[JournaloftheIndianChemicalSociety,2022,vol.99,#3]

[21]Zhang,Peng;Li,Xiaoyan;Qi,Xinghao;Sun,Hongjian;Fuhr,Olaf;Fenske,Dieter[RSCAdvances,2018,vol.8,#25,p.14092-14099]

[22]Khurana;Chauhan[SyntheticCommunications,2001,vol.31,#22,p.3485-3489]

[23]Lau,CheukK.;Tardif,Sylvie;Dufresne,Claude;Scheigetz,John[JournalofOrganicChemistry,1989,vol.54,#2,p.491-494]

[24]Locationinpatent:experimentalpartKumar,K.Anil;Gowda,D.Channe[E-JournalofChemistry,2011,vol.8,#1,p.49-52]

[25]Wei,Yawen;Xue,Dong;Lei,Qian;Wang,Chao;Xiao,Jianliang[GreenChemistry,2013,vol.15,#3,p.629-634]

[26]Kuroda,Kazunori;Nagamatsu,Tomohisa;Yanada,Reiko;Yoneda,Fumio[JournaloftheChemicalSociety.PerkintransactionsI,1993,#5,p.547-550]

[27]Kim,BokTae;Cho,ChanSik;Kim,Tae-Jeong;Shim,SangChul[JournalofChemicalResearch-PartS,2003,#6,p.368-369]

[28]Demmel,GabrielI.;Bordón,DanielaL.;Vázquez,AnaM.;Decarlini,MaríaF.;DíazPanero,Mariángeles;Rossi,LauraI.;Aimar,MarioL.[BiocatalysisandBiotransformation,2023,vol.41,#2,p.93-107]

[29]Metayer;Dat-Xuong[BulletindelaSocieteChimiquedeFrance,1954,p.615,617]

[30]Hook,IngridL.;Ryan,Shane;Sheridan,Helen[Phytochemistry,1999,vol.51,#5,p.621-627]

[31]He,Chao;Zhang,Xiaohui;Huang,Ruofeng;Pan,Jing;Li,Jiaqiang;Ling,Xuege;Xiong,Yan;Zhu,Xiangming[TetrahedronLetters,2014,vol.55,#32,p.4458-4462]

[32]Wang,Lin;Sun,Hongjian;Li,Xiaoyan[EuropeanJournalofInorganicChemistry,2015,vol.2015,#16,p.2732-2743]

[33]Zheng,Tingting;Li,Junye;Zhang,Shumiao;Xue,Benjing;Sun,Hongjian;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[Organometallics,2016,vol.35,#20,p.3538-3545]

[34]Christie,Francesca;Zanotti-Gerosa,Antonio;Grainger,Damian[ChemCatChem,2018,vol.10,#5,p.1012-1018]

[35]Nath,Utpal;Chowdhury,Deepan;Pan,SubhasChandra[AdvancedSynthesisandCatalysis,2018,vol.360,#8,p.1628-1633]

[36]Wang,Yangyang;Ren,Shishuai;Zhang,Wenbo;Xue,Benjing;Qi,Xinghao;Sun,Hongjian;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[CatalysisCommunications,2018,vol.115,p.1-5]

[37]Yang,Jin;Yuan,Man;Xu,Dan;Zhao,Hong;Zhu,Yangyang;Fan,Menying;Zhang,Fengwei;Dong,Zhengping[JournalofMaterialsChemistryA,2018,vol.6,#37,p.18242-18251]

[38]Qi,Xinghao;Zhao,Hua;Sun,Hongjian;Li,Xiaoyan;Fuhr,Olaf;Fenske,Dieter[NewJournalofChemistry,2018,vol.42,#20,p.16583-16590]

[39]Qi,Xinghao;Zheng,Tingting;Zhou,Junhao;Dong,Yanhong;Zuo,Xia;Li,Xiaoyan;Sun,Hongjian;Fuhr,Olaf;Fenske,Dieter[Organometallics,2019,vol.38,#2,p.268-277]

[40]Du,Xinyu;Qi,Xinghao;Li,Kai;Li,Xiaoyan;Sun,Hongjian;Fuhr,Olaf;Fenske,Dieter[AppliedOrganometallicChemistry,2021,vol.35,#8]

[41]Battu,Satyanarayana;Joolakanti,HimaBindhu;Kamepalli,Ramanjaneyulu;Miryala,Jeevanreddy[JournalofMolecularStructure,2021,vol.1242]

[42]Fan,Qingqing;Du,Xinyu;Yang,Wenjing;Li,Qingshuang;Huang,Wei;Sun,Hongjian;Hinz,Alexander;Li,Xiaoyan[DaltonTransactions,2023,vol.52,#20,p.6712-6721]

874-42-0    1777-82-8    50-84-0 

[1]vandeLande[RecueildesTravauxChimiquesdesPays-Bas,1932,vol.51,p.98,109]

[2]vandeLande[RecueildesTravauxChimiquesdesPays-Bas,1932,vol.51,p.98,109]

[3]Zhao,Qiangqiang;Sun,Jie;Liu,Baojiang;He,Jinxin[DyesandPigments,2013,vol.99,#2,p.339-347]

50-84-0    1777-82-8 

[1]Patent:CN106117028,2016,A.Locationinpatent:Paragraph0047;0048;0049;0050;0051;0052

[2]JournaloftheAmericanChemicalSociety,1973,vol.95,p.3757-3763

[3]Synlett,1997,vol.1997,p.989-991

[4]ChemicalCommunications,2019,vol.55,p.1386-1389

1777-82-8    874-42-0 

[1]AppliedOrganometallicChemistry,2020

[2]RSCAdvances,2016,vol.6,p.63717-63723

[3]JournalofMaterialsChemistryA,2016,vol.4,p.3933-3946

[4]JournalofPhotochemistryandPhotobiologyA:Chemistry,2020,vol.389

[5]Synthesis,2006,p.2043-2046

[6]ResearchonChemicalIntermediates,2013,vol.39,p.3337-3343

[7]JournaloftheChineseChemicalSociety,2014,vol.61,p.1039-1044

[8]JournaloftheChineseChemicalSociety,2007,vol.54,p.1257-1260

[9]JournaloftheChineseChemicalSociety,2007,vol.54,p.1257-1260

[10]JournaloftheIranianChemicalSociety,2011,vol.8,p.1082-1090

[11]AppliedOrganometallicChemistry,2018,vol.32

[12]JournaloftheAmericanChemicalSociety,2009,vol.131,p.251-262

[13]ChemicalCommunications,2013,vol.49,p.7908-7910

[14]SyntheticCommunications,2015,vol.45,p.1334-1341

[15]RSCAdvances,2015,vol.5,p.70577-70585

[16]RSCAdvances,2016,vol.6,p.51347-51355

[17]MendeleevCommunications,2005,vol.15,p.113-116

[18]Tetrahedron,2015,vol.71,p.8725-8731

[19]ChineseChemicalLetters,2012,vol.23,p.21-24

[20]JournaloftheIranianChemicalSociety,2016,vol.13,p.1963-1975

[21]AppliedOrganometallicChemistry,2018,vol.32

[22]JournaloftheChineseChemicalSociety,2007,vol.54,p.465-468

[23]AppliedOrganometallicChemistry,2016,vol.30,p.577-580

[24]Patent:CN107400050,2017,A.Locationinpatent:Paragraph0005;0015;0017;0018;0020

[25]Organicandbiomolecularchemistry,2020,vol.18,p.2326-2330

[26]AppliedOrganometallicChemistry,2017,vol.31

[27]AppliedOrganometallicChemistry,2017,vol.31

[28]TetrahedronLetters,2005,vol.46,p.8483-8486

[29]JournalofChemicalResearch,2006,p.188-191

[30]TetrahedronLetters,2006,vol.47,p.8953-8957

[31]GreenChemistry,2012,vol.14,p.1493-1501

[32]TransitionMetalChemistry,2018,vol.43,p.579-589

[33]PolishJournalofChemistry,2004,vol.78,p.741-744

[34]CatalysisLetters,2018,vol.148,p.1110-1123

[35]BioorganicandMedicinalChemistry,2005,vol.13,p.2901-2905

[36]TransitionMetalChemistry,2016,vol.41,p.767-774

[37]CatalysisCommunications,2019,vol.124,p.76-80

[38]JournalofPhotochemistryandPhotobiologyA:Chemistry,2019,vol.371,p.173-181

[39]SouthAfricanJournalofChemistry,2007,vol.60,p.58-61

[40]JournalofChemicalSciences,2015,vol.127,p.1321-1328

[41]JournalofChemicalResearch,2007,p.252-256

[42]ChemPlusChem,2014,vol.79,p.217-222

[43]JournalofOrganicChemistry,2017,vol.82,p.7165-7175

[44]CatalysisLetters,2014,vol.144,p.355-363

[45]CatalysisCommunications,2016,vol.77,p.9-12

[46]CatalysisCommunications,2017,vol.101,p.98-101

[47]PolishJournalofChemistry,2006,vol.80,p.1377-1383

[48]RSCAdvances,2014,vol.4,p.49974-49978

[49]RSCAdvances,2014,vol.4,p.34681-34686

[50]EuropeanJournalofInorganicChemistry,2020,vol.2020,p.480-490

[51]ActachemicaScandinavica.SeriesB:Organicchemistryandbiochemistry,1983,vol.37,p.499-508

[52]TetrahedronLetters,1999,vol.40,p.3723-3726

[53]ZeitschriftfurNaturforschung,B:ChemicalSciences,2007,vol.62,p.537-539

[54]ZeitschriftfurNaturforschung,B:ChemicalSciences,2006,vol.61,p.326-330

[55]ZeitschriftfurNaturforschung,B:ChemicalSciences,2006,vol.61,p.326-330

[56]SouthAfricanJournalofChemistry,2008,vol.61,p.9-12

[57]ChemicalCommunications,2009,p.5555-5557

[58]GreenChemistry,2011,vol.13,p.991-997

[59]OrganicandBiomolecularChemistry,2011,vol.9,p.4194-4198

[60]Chemistry-AEuropeanJournal,2011,vol.17,p.6056-6060

[61]AsianJournalofChemistry,2011,vol.23,p.829-831

[62]AdvancedSynthesisandCatalysis,2012,vol.354,p.1319-1326

[63]Chemistry-AEuropeanJournal,2012,vol.18,p.8634-8640

[64]TetrahedronLetters,2012,vol.53,p.4962-4965

[65]Chemistry-AEuropeanJournal,2012,vol.18,p.13520-13530

[66]Polyhedron,2012,vol.47,p.94-103

[67]ComptesRendusChimie,2013,vol.16,p.109-113

[68]DaltonTransactions,2013,vol.42,p.6829-6839

[69]RSCAdvances,2013,vol.3,p.19255-19258

[70]ChineseJournalofChemistry,2014,vol.32,p.117-122

[71]JournalofMolecularCatalysisA:Chemical,2014,vol.392,p.8-15

[72]SyntheticCommunications,2014,vol.44,p.2818-2825

[73]EuropeanJournalofInorganicChemistry,2014,vol.2014,p.6066-6074

[74]AppliedOrganometallicChemistry,2015,vol.29,p.561-565

[75]Polyhedron,2015,vol.99,p.260-265

[76]Polyhedron,2016,vol.106,p.153-162

[77]JournaloftheIranianChemicalSociety,2016,vol.13,p.1463-1470

[78]ChemPlusChem,2016,vol.81,p.1160-1165

[79]ChemSusChem,2014,vol.7,p.2735-2741

[80]ChemistryOpen,2017,vol.6,p.112-120

[81]JournaloftheIranianChemicalSociety,2017,vol.14,p.1317-1323

[82]JournalofChemistry,2017,vol.2017

[83]NewJournalofChemistry,2017,vol.41,p.3405-3413

[84]RSCAdvances,2018,vol.8,p.6768-6780

[85]JournaloftheIranianChemicalSociety,2018,vol.15,p.893-904

[86]RSCAdvances,2017,vol.7,p.55336-55349

[87]ChemCatChem,2018,vol.10,p.1542-1546

[88]AppliedCatalysisA:General,2018,vol.563,p.185-195

[89]Polymer,2018,vol.149,p.229-237

[90]AppliedOrganometallicChemistry,2018,vol.32

[91]OrganicProcessResearchandDevelopment,2018,vol.22,p.1298-1305

[92]JournaloftheIranianChemicalSociety,2019,vol.16,p.563-570

[93]Molecularcatalysis,2019,vol.468,p.75-79

[94]CatalysisLetters,2019,vol.149,p.1237-1249

[95]AppliedOrganometallicChemistry,2020,vol.34

[96]NewJournalofChemistry,2020,vol.44,p.4426-4439

[97]AppliedOrganometallicChemistry,2020,vol.34

[98]ACSCombinatorialScience,2020,vol.22,p.70-79

[99]JournaloftheIranianChemicalSociety,2020

1777-82-8    20443-99-6 

[1]TetrahedronLetters,2014,vol.55,p.90-93

[2]Patent:CN106117028,2016,A.Locationinpatent:Paragraph0057;0058

[3]OrganicProcessResearchandDevelopment,2002,vol.6,p.190-191

[4]MonatsheftefurChemie,2004,vol.135,p.1251-1255

[5]JournalofMedicinalChemistry,1989,vol.32,p.1757-1763

[6]JournalofMedicinalChemistry,1996,vol.39,p.3569-3584

[7]ScientiaPharmaceutica,2001,vol.69,p.329-350

[8]Chemistry-AEuropeanJournal,2019,vol.25,p.6290-6294

Literature fold

Title: Randomised, double-blind, placebo-controlled study of a single dose of an amylmetacresol/2,4-dichlorobenzyl alcohol plus lidocaine lozenge or a hexylresorcinol lozenge for the treatment of acute sore throat due to upper respiratory tract infection.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques20120101

Title: Acute sore throat revisited: clinical and experimental evidence for the efficacy of over-the-counter AMC/DCBA throat lozenges.

Journal: International journal of clinical practice20110501

Title: A multicentre, randomised, double-blind, single-dose study assessing the efficacy of AMC/DCBA Warm lozenge or AMC/DCBA Cool lozenge in the relief of acute sore throat.

Journal: BMC family practice20110101

Title: Rapid relief of acute sore throat with AMC/DCBA throat lozenges: randomised controlled trial.

Journal: International journal of clinical practice20100101

Title: Topical antiseptics for the treatment of sore throat block voltage-gated neuronal sodium channels in a local anaesthetic-like manner.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20090801

Title: Allergic contact dermatitis from dichlorobenzyl alcohol in a patient with multiple contact allergies.

Journal: Contact dermatitis20090501

Title: FT-Raman and FT-IR spectra, ab initio and density functional studies of 3,4-dichlorobenzyl alcohol.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20061101

Title: A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV.

Journal: Antiviral chemistry & chemotherapy20050101

Title: Efficacy of three surface disinfectants for dental radiographic films and gloves.

Journal: Journal of dentistry20040701

Title: Morokutti-Kurz M , et al. Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat. Int J Gen Med. 2017 Feb 28;10:53-60.

Title: Matthews D, et al. Spectrum of bactericidal action of amylmetacresol/2,4-dichlorobenzyl alcohol lozenges against oropharyngeal organisms implicated in pharyngitis. Int J Gen Med. 2018 Nov 28;11:451-456.

Building Blocks More >
1780-72-9
1780-72-9
4-Bromo-3-methyl-1H-pyrazol-5-amine
AA0025MT | MFCD03412169
178396-31-1
178396-31-1
6-Bromo-8-methylquinoline
AA0025WE | MFCD11847622
1788036-28-1
1788036-28-1
tert-Butyl n-[(1s,3s)-3-aminocyclohexyl]carbamate
AA00268R | MFCD18632893
179056-98-5
179056-98-5
2,4-Dichloro-6-methylpyridin-3-amine
AA0026NZ | MFCD07774093
17945-79-8
17945-79-8
4-(Pyridin-2-yl)butan-1-ol
AA0026XL | MFCD12828284
179737-33-8
179737-33-8
2,3-Dibromo-1,4-difluorobenzene
AA00275X | MFCD12922620
183311-28-6
183311-28-6
Carbamic acid, n-(3-amino-4-pyridinyl)-, 1,1-dimethylethyl ester
AA0027FG | MFCD10699435
201849-21-0
201849-21-0
4-Bromo-2-chloro-1-isopropoxybenzene
AA0027SZ | MFCD00070757
20240-58-8
20240-58-8
3-Allyl-4-hydroxy-5-methoxybenzaldehyde
AA00284W | MFCD01590282
20291-40-1
20291-40-1
7-Methoxy-7-oxoheptanoic acid
AA0028G8 | MFCD00040445
Submit
© 2017 AA BLOCKS, INC. All rights reserved.