Name: Name:2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-
Brand: AABLOCKS
SKU: AA0025W7
Rating: 90 (10 reviews)

Catalog No.: AA0025W7

17834-04-7 | 2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-

Pack Size： 5mg

Purity：

2 weeks

$1,960.00 $1,372.00

Pack Size： 25mg

Purity：

2 weeks

$4,470.00 $3,129.00

Quantity

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Technical Information

Catalog Number: AA0025W7

Chemical Name: 2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-

CAS Number: 17834-04-7

Molecular Formula: C19H16O5

Molecular Weight: 324.3273

MDL Number: MFCD00272667

SMILES: CC(=O)CC(c1c(=O)oc2c(c1O)cccc2O)c1ccccc1

Properties

Form: Solid

MP: 190-192°C (dec.)

Storage: -20 ℃;

Complexity: 532

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 24

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 1

Undefined Bond Stereocenter Count: 0

XLogP3: 2.3

Literature fold

Title: Warfarin is an effective modifier of multiple UDP-glucuronosyltransferase enzymes: evaluation of its potential to alter the pharmacokinetics of zidovudine.

Journal: Journal of pharmaceutical sciences20150101

Title: Responsiveness to low-dose warfarin associated with genetic variants of VKORC1, CYP2C9, CYP2C19, and CYP4F2 in an Indonesian population.

Journal: European journal of clinical pharmacology20130301

Title: Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases.

Journal: The Journal of pharmacology and experimental therapeutics20120101

Title: Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.

Journal: Chemical research in toxicology20100517

Title: Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver.

Journal: Drug metabolism and pharmacokinetics20090101

Title: Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.

Journal: Drug metabolism and disposition: the biological fate of chemicals20081101