Name: Name:1-(2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
Brand: AABLOCKS
SKU: AA00ANPY
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00ANPY

Chemical Name: 1-(2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea

CAS Number: 179343-17-0

Molecular Formula: C18H18Cl2N6O

Molecular Weight: 405.2811

MDL Number: MFCD28138124

SMILES: O=C(NC(C)(C)C)Nc1nc2nc(N)ncc2cc1c1c(Cl)cccc1Cl

Properties

Complexity: 521

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 27

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 3

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 3.7

Literature fold

Title: Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1.

Journal: Bioorganic & medicinal chemistry letters20050401

Title: Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity.

Journal: Journal of medicinal chemistry20010607

179343-17-0 | 1-(2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea