Home Amines 179386-44-8
179386-44-8,MFCD09832637
Catalog No.:AA00ABW6

179386-44-8 | (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate

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1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$143.00   $100.00
- +
10mg
≥98%
in stock  
$263.00   $184.00
- +
25mg
98%
in stock  
$600.00   $420.00
- +
50mg
98%
in stock  
$1,088.00   $762.00
- +
100mg
98%
in stock  
$1,845.00   $1,292.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABW6
Chemical Name:
(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate
CAS Number:
179386-44-8
Molecular Formula:
C15H17N3O5
Molecular Weight:
319.3126
MDL Number:
MFCD09832637
SMILES:
OC(=O)/C=C\C(=O)O.CN[C@@H]1Cc2cccc3c2n(C1)c(=O)[nH]3
Properties
Computed Properties
 
Complexity:
400  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
3  

Literature

Title: Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists.

Journal: Psychopharmacology 20120101

Title: Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: The effects of the dopamine D2 agonist sumanirole on prepulse inhibition in rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100601

Title: The dopamine D3 receptor partial agonist CJB 090 inhibits the discriminative stimulus but not the reinforcing or priming effects of cocaine in squirrel monkeys.

Journal: Psychopharmacology 20090901

Title: The discriminative stimulus effects of dopamine D2- and D3-preferring agonists in rats.

Journal: Psychopharmacology 20090401

Title: Motor sequence learning in primate: role of the D2 receptor in movement chunking during consolidation.

Journal: Behavioural brain research 20090302

Title: Asymmetric synthesis of tetrahydroquinolin-3-ols via CoCl2-catalyzed reductive cyclization of nitro cyclic sulfites with NaBH4.

Journal: Organic letters 20090219

Title: Sumanirole versus placebo or ropinirole for the adjunctive treatment of patients with advanced Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070315

Title: A comparison of sumanirole versus placebo or ropinirole for the treatment of patients with early Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070315

Title: Efficacy and tolerability of sumanirole in restless legs syndrome: a phase II, randomized, double-blind, placebo-controlled, dose-response study.

Journal: Sleep medicine 20070301

Title: The effects of a selective dopamine D2 receptor agonist on behavioral and pathological outcome in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Sumanirole, a highly dopamine D2-selective receptor agonist: in vitro and in vivo pharmacological characterization and efficacy in animal models of Parkinson's disease.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Sumanirole Pharmacia.

Journal: Current opinion in investigational drugs (London, England : 2000) 20030101

Title: Arthur G. Romero, et al. Synthesis of the Selective D2 Receptor Agonist PNU-95666E fromD-Phenylalanine Using a Sequential Oxidative CyclizationStrategy. J. Org. Chem. 1997, 62, 6582-6587

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Tags:179386-44-8 Molecular Formula|179386-44-8 MDL|179386-44-8 SMILES|179386-44-8 (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate