17990-42-0,MFCD09752411
Catalog No.:AA0027AQ

17990-42-0 | Olean-12-en-28-oic acid, 3-oxo-

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Purity
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50mg
98%
1 week  
$146.00   $102.00
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  • Technical Information
  • Properties
  • Literature
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Technical Information
Catalog Number:
AA0027AQ
Chemical Name:
Olean-12-en-28-oic acid, 3-oxo-
CAS Number:
17990-42-0
Molecular Formula:
C30H46O3
Molecular Weight:
454.6844
MDL Number:
MFCD09752411
SMILES:
OC(=O)[C@]12CC[C@@]3(C(=CC[C@H]4[C@@]3(C)CC[C@@H]3[C@]4(C)CCC(=O)C3(C)C)[C@@H]2CC(CC1)(C)C)C
Properties
Computed Properties
 
Complexity:
927  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
7.2  

Literature

Title: Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.

Journal: Journal of medicinal chemistry 20130613

Title: Distribution and expression characteristics of triterpenoids and OSC genes in white birch (Betula platyphylla suk.).

Journal: Molecular biology reports 20120301

Title: Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Synthesis and biological evaluation of oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B.

Journal: Journal of natural products 20101129

Title: Synthesis and evaluation of a novel series of heterocyclic oleanolic acid derivatives with anti-osteoclast formation activity.

Journal: European journal of medicinal chemistry 20090701

Title: Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.

Journal: Journal of natural products 20081001

Title: Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.

Journal: Bioorganic & medicinal chemistry 20080915

Title: Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.

Journal: Journal of medicinal chemistry 20080626

Title: Phytochemical and biological studies on Saudi Commiphora opobalsamum L.

Journal: Natural product research 20070501

Title: Chemical constituents and antifilarial activity of Lantana camara against human lymphatic filariid Brugia malayi and rodent filariid Acanthocheilonema viteae maintained in rodent hosts.

Journal: Parasitology research 20070201

Title: Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.

Journal: Bioorganic & medicinal chemistry letters 20060601

Title: Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action.

Journal: Bioorganic & medicinal chemistry letters 20050502

Title: [Studies on the chemical constituents from the leaf of Liquidambar formosana Hance].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050401

Title: Triterpenoids. Part 21: Oleanolic acid azaderivatives as percutaneous transport promoters.

Journal: Bioorganic & medicinal chemistry letters 20040920

Title: Inhibition of cytochrome P450 activities by oleanolic acid and ursolic acid in human liver microsomes.

Journal: Life sciences 20040416

Title: Saponins from Swartzia langsdorffii: biological activities.

Journal: Memorias do Instituto Oswaldo Cruz 20030701

Title: Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity.

Journal: European journal of pharmacology 20010928

Title: Oleanane triterpenes from Junellia tridens.

Journal: Journal of natural products 20001201

Title: Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.

Journal: Journal of natural products 19980901

Title: Giner-Larza EM et al.Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity.Eur J Pharmacol.Sep 28;428(1):137-43.doi:10.1016/S0014-2999(01)01290-0(2001)

Title: Fabio Mengoni.Anti-HIV Activity of Oleanolic Acid on Infected Human Mononuclear Cells.Planta Med 68(2): 111-114.DOI: 10.1055/s-2002-20256(2002)

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Tags:17990-42-0 Molecular Formula|17990-42-0 MDL|17990-42-0 SMILES|17990-42-0 Olean-12-en-28-oic acid, 3-oxo-
Catalog No.: AA0027AQ
17990-42-0,MFCD09752411
17990-42-0 | Olean-12-en-28-oic acid, 3-oxo-
Pack Size: 50mg
Purity: 98%
1 week
$146.00 $102.00
Quantity
- +
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Technical Information
Catalog Number: AA0027AQ
Chemical Name: Olean-12-en-28-oic acid, 3-oxo-
CAS Number: 17990-42-0
Molecular Formula: C30H46O3
Molecular Weight: 454.6844
MDL Number: MFCD09752411
SMILES: OC(=O)[C@]12CC[C@@]3(C(=CC[C@H]4[C@@]3(C)CC[C@@H]3[C@]4(C)CCC(=O)C3(C)C)[C@@H]2CC(CC1)(C)C)C
Properties
Complexity: 927  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 7  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 33  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 7.2  
Literature fold

Title: Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.

Journal: Journal of medicinal chemistry20130613

Title: Distribution and expression characteristics of triterpenoids and OSC genes in white birch (Betula platyphylla suk.).

Journal: Molecular biology reports20120301

Title: Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.

Journal: Bioorganic & medicinal chemistry letters20101215

Title: Synthesis and biological evaluation of oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B.

Journal: Journal of natural products20101129

Title: Synthesis and evaluation of a novel series of heterocyclic oleanolic acid derivatives with anti-osteoclast formation activity.

Journal: European journal of medicinal chemistry20090701

Title: Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.

Journal: Journal of natural products20081001

Title: Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.

Journal: Bioorganic & medicinal chemistry20080915

Title: Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.

Journal: Journal of medicinal chemistry20080626

Title: Phytochemical and biological studies on Saudi Commiphora opobalsamum L.

Journal: Natural product research20070501

Title: Chemical constituents and antifilarial activity of Lantana camara against human lymphatic filariid Brugia malayi and rodent filariid Acanthocheilonema viteae maintained in rodent hosts.

Journal: Parasitology research20070201

Title: Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.

Journal: Bioorganic & medicinal chemistry letters20060601

Title: Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action.

Journal: Bioorganic & medicinal chemistry letters20050502

Title: [Studies on the chemical constituents from the leaf of Liquidambar formosana Hance].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20050401

Title: Triterpenoids. Part 21: Oleanolic acid azaderivatives as percutaneous transport promoters.

Journal: Bioorganic & medicinal chemistry letters20040920

Title: Inhibition of cytochrome P450 activities by oleanolic acid and ursolic acid in human liver microsomes.

Journal: Life sciences20040416

Title: Saponins from Swartzia langsdorffii: biological activities.

Journal: Memorias do Instituto Oswaldo Cruz20030701

Title: Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity.

Journal: European journal of pharmacology20010928

Title: Oleanane triterpenes from Junellia tridens.

Journal: Journal of natural products20001201

Title: Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.

Journal: Journal of natural products19980901

Title: Giner-Larza EM et al.Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity.Eur J Pharmacol.Sep 28;428(1):137-43.doi:10.1016/S0014-2999(01)01290-0(2001)

Title: Fabio Mengoni.Anti-HIV Activity of Oleanolic Acid on Infected Human Mononuclear Cells.Planta Med 68(2): 111-114.DOI: 10.1055/s-2002-20256(2002)

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