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Home Oxazoles 1801344-14-8
1801344-14-8,MFCD32693907
Catalog No.:AA01PXUL

1801344-14-8 | 4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-

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1mg
≥98%
in stock  
$48.00   $33.00
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5mg
≥98%
in stock  
$153.00   $107.00
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10mg
≥98%
in stock  
$280.00   $196.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01PXUL
Chemical Name:
4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-
CAS Number:
1801344-14-8
Molecular Formula:
C24H25N7O5
Molecular Weight:
491.4992
MDL Number:
MFCD32693907
SMILES:
O[C@@H]1CCN(C1)c1nc2nc(oc2cc1NC(=O)c1coc(n1)c1ccnc(c1)C)N1CCOCC1
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-WO2015/104688,2015,A1Locationinpatent:Page/Pagecolumn73-74

[1]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-WO2017/9806,2017,A1Locationinpatent:Page/Pagecolumn79

[1]Gummadi,VenkateshwarRao;Boruah,Anima;Ainan,BharathiRaja;Vare,BrahmaReddy;Manda,Srinivas;Gondle,HariPrakash;Kumar,ShivaNagendra;Mukherjee,Subhendu;Gore,SurajT.;Krishnamurthy,NarasimhaRao;Marappan,Sivapriya;Nayak,ShilpaS.;Nellore,Kavitha;Balasubramanian,WesleyRoy;Bhumireddy,Archana;Giri,Sanjeev;Gopinath,Sreevalsam;Samiulla,DodheriS.;Daginakatte,Girish;Basavaraju,Aravind;Chelur,Shekar;Eswarappa,Rajesh;Belliappa,Charamanna;Subramanya,HosahalliS.;Booher,RobertN.;Ramachandra,Murali;Samajdar,Susanta[ACSMedicinalChemistryLetters,2020,vol.11,#12,p.2374-2381]

[1]Gummadi,VenkateshwarRao;Boruah,Anima;Ainan,BharathiRaja;Vare,BrahmaReddy;Manda,Srinivas;Gondle,HariPrakash;Kumar,ShivaNagendra;Mukherjee,Subhendu;Gore,SurajT.;Krishnamurthy,NarasimhaRao;Marappan,Sivapriya;Nayak,ShilpaS.;Nellore,Kavitha;Balasubramanian,WesleyRoy;Bhumireddy,Archana;Giri,Sanjeev;Gopinath,Sreevalsam;Samiulla,DodheriS.;Daginakatte,Girish;Basavaraju,Aravind;Chelur,Shekar;Eswarappa,Rajesh;Belliappa,Charamanna;Subramanya,HosahalliS.;Booher,RobertN.;Ramachandra,Murali;Samajdar,Susanta[ACSMedicinalChemistryLetters,2020,vol.11,#12,p.2374-2381]

Literature

Title: Wiese MD, et al. Investigational IRAK-4 inhibitors for the treatment of rheumatoid arthritis. Expert Opin Investig Drugs. 2020 Apr 17:1-8.

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Tags:1801344-14-8 Molecular Formula|1801344-14-8 MDL|1801344-14-8 SMILES|1801344-14-8 4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-