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Home Other Building Blocks 1802220-02-5
1802220-02-5,MFCD31544350
Catalog No.:AA003ARB

1802220-02-5 | Tpx-0005

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%(HPLC)
in stock  
$24.00   $17.00
- +
10mg
98%(HPLC)
in stock  
$27.00   $19.00
- +
25mg
98%(HPLC)
in stock  
$45.00   $32.00
- +
100mg
98%(HPLC)
in stock  
$108.00   $76.00
- +
250mg
98%(HPLC)
in stock  
$216.00   $152.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003ARB
Chemical Name:
Tpx-0005
CAS Number:
1802220-02-5
Molecular Formula:
C18H18FN5O2
Molecular Weight:
355.3662
MDL Number:
MFCD31544350
SMILES:
C[C@H]1CNC(=O)c2cnn3c2nc(N[C@@H](c2c(O1)ccc(c2)F)C)cc3
Properties
Computed Properties
 
Complexity:
524  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
XLogP3:
2.1  

Literature

Title: Dayong Zhai, et al. Abstract 2132: The novel, rationally-designed, ALK/SRC inhibitor TPX-0005 overcomes multiple acquired resistance mechanisms to current ALK inhibitors. Cancer Research. July 2016

Title: Karachaliou N, et al. Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis. EBioMedicine. 2018 Mar;29:112-127.

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SDS
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Tags:1802220-02-5 Molecular Formula|1802220-02-5 MDL|1802220-02-5 SMILES|1802220-02-5 Tpx-0005