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1809249-37-3,MFCD31657351
Catalog No.:AA01FNMZ

1809249-37-3 | Remdesivir

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
99%
in stock  
$6.00   $4.00
- +
250mg
99%
in stock  
$12.00   $8.00
- +
1g
99%
in stock  
$33.00   $23.00
- +
5g
99%
in stock  
$104.00   $73.00
- +
25g
99%
in stock  
$514.00   $360.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01FNMZ
Chemical Name:
Remdesivir
CAS Number:
1809249-37-3
Molecular Formula:
C27H35N6O8P
Molecular Weight:
602.5760
MDL Number:
MFCD31657351
SMILES:
CCC(COC(=O)[C@@H](NP(=O)(Oc1ccccc1)OC[C@H]1O[C@@]([C@@H]([C@@H]1O)O)(C#N)c1ccc2n1ncnc2N)C)CC
Properties
Computed Properties
 
Complexity:
1010  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
14  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.9  

Downstream Synthesis Route
(S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-3,4-bis((tertbutyldimethylsilyl)oxy)-5-cyanotetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
  1809249-37-3 

[1]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1Locationinpatent:Paragraph0260

[1]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[2]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[3]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[4]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[5]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[6]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[7]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[8]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[9]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[10]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[11]CurrentPatentAssignee:GILEADSCIENCESINC-US2017/71964,2017,A1

[1]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[2]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[3]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[4]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[5]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[6]CurrentPatentAssignee:GILEADSCIENCESINC-US2017/71964,2017,A1

[7]CurrentPatentAssignee:ANZALPPHARMASOLUTIONSPVT-US2021/161927,2021,A1

[8]CurrentPatentAssignee:ANZALPPHARMASOLUTIONSPVT-US2021/161927,2021,A1

1191237-69-0   
(2S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

[1]Patent:WO2016/69826,2016,A1

[2]Patent:WO2016/69826,2016,A1

[3]Patent:US2017/71964,2017,A1

[4]Patent:WO2017/184668,2017,A1

1191237-69-0    1439900-56-7   
(2S)-2-ethylbutyl2-(((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
 
(2S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

[1]Patent:WO2016/69826,2016,A1.Locationinpatent:Paragraph0198-0201

[2]Patent:WO2017/184668,2017,A1

Literature

Title: Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.

Title: Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

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SDS
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Tags:1809249-37-3 Molecular Formula|1809249-37-3 MDL|1809249-37-3 SMILES|1809249-37-3 Remdesivir
Catalog No.: AA01FNMZ
1809249-37-3,MFCD31657351
1809249-37-3 | Remdesivir
Pack Size： 10mg
Purity： 99%
in stock
$6.00 $4.00
Pack Size： 250mg
Purity： 99%
in stock
$12.00 $8.00
Pack Size： 1g
Purity： 99%
in stock
$33.00 $23.00
Pack Size： 5g
Purity： 99%
in stock
$104.00 $73.00
Pack Size： 25g
Purity： 99%
in stock
$514.00 $360.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA01FNMZ
Chemical Name: Remdesivir
CAS Number: 1809249-37-3
Molecular Formula: C27H35N6O8P
Molecular Weight: 602.5760
MDL Number: MFCD31657351
SMILES: CCC(COC(=O)[C@@H](NP(=O)(Oc1ccccc1)OC[C@H]1O[C@@]([C@@H]([C@@H]1O)O)(C#N)c1ccc2n1ncnc2N)C)CC
Properties
Complexity: 1010  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 6  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 42  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 14  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.9  
Downstream Synthesis Route
(S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-3,4-bis((tertbutyldimethylsilyl)oxy)-5-cyanotetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
  1809249-37-3 

[1]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1Locationinpatent:Paragraph0260

1355049-94-3    1809249-37-3 

[1]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[2]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[3]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[4]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[5]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[6]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[7]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[8]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[9]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[10]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[11]CurrentPatentAssignee:GILEADSCIENCESINC-US2017/71964,2017,A1

1191237-68-9    1809249-37-3 

[1]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[2]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[3]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[4]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[5]CurrentPatentAssignee:GILEADSCIENCESINC;GILDSCIENCE-WO2016/69826,2016,A1

[6]CurrentPatentAssignee:GILEADSCIENCESINC-US2017/71964,2017,A1

[7]CurrentPatentAssignee:ANZALPPHARMASOLUTIONSPVT-US2021/161927,2021,A1

[8]CurrentPatentAssignee:ANZALPPHARMASOLUTIONSPVT-US2021/161927,2021,A1

1191237-69-0   
(2S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

[1]Patent:WO2016/69826,2016,A1

[2]Patent:WO2016/69826,2016,A1

[3]Patent:US2017/71964,2017,A1

[4]Patent:WO2017/184668,2017,A1

1191237-69-0    1439900-56-7   
(2S)-2-ethylbutyl2-(((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
 
(2S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo2,1-f1,2,4triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

[1]Patent:WO2016/69826,2016,A1.Locationinpatent:Paragraph0198-0201

[2]Patent:WO2017/184668,2017,A1

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