[1]Patent:US2003/232871,2003,A1,.Locationinpatent:Page5
[2]Patent:US2001/3752,2001,A1,
[3]JournalofMedicinalChemistry,2004,vol.47,#20,p.4881-4890
[4]JournalofMedicinalChemistry,2004,vol.47,#20,p.4881-4890
[5]JournalofMedicinalChemistry,2000,vol.43,#5,p.775-777
[6]Patent:WO2005/23189,2005,A2,.Locationinpatent:Page/Pagecolumn73-74
[7]Patent:CN104447600,2016,B,
[8]Patent:EP1223167,2002,A2,
[1]Patent:CN106008387,2016,A,.Locationinpatent:Paragraph0020;0045;0046;0047
[1]Patent:CN106008386,2016,A,.Locationinpatent:Paragraph0021;0044;0045;0046
[2]Patent:CN105859647,2016,A,.Locationinpatent:Paragraph0045;0046;0047
[3]JournalofMedicinalChemistry,2004,vol.47,#20,p.4881-4890
[4]Patent:CN105418528,2016,A,.Locationinpatent:Paragraph0063;0064
[5]Patent:CN104193694,2016,B,.Locationinpatent:Paragraph0032-0035
[6]Patent:EP1550658,2005,A1,.Locationinpatent:Page/Pagecolumn9
[7]SyntheticCommunications,2012,vol.42,#5,p.639-649
[8]SyntheticCommunications,2012,vol.42,#5,p.639-649
[9]Patent:CN104447600,2016,B,.Locationinpatent:Paragraph0085;0087
[10]Patent:CN107137361,2017,A,
[1]Patent:EP1550658,2005,A1,.Locationinpatent:Page/Pagecolumn7
[2]SyntheticCommunications,2012,vol.42,#5,p.639-649
[3]Patent:EP1223167,2002,A2,.Locationinpatent:Page23
[4]JournalofMedicinalChemistry,2000,vol.43,#5,p.775-777
[5]Patent:US2005/272787,2005,A1,.Locationinpatent:Page/Pagecolumn2
[6]Patent:US2005/272787,2005,A1,.Locationinpatent:Page/Pagecolumn2
[7]Patent:WO2005/123701,2005,A1,.Locationinpatent:Page/Pagecolumn38-39
[8]Patent:WO2005/85218,2005,A1,.Locationinpatent:Page/Pagecolumn10
[9]Patent:CN107137361,2017,A,.Locationinpatent:Paragraph0031-0033
[1]Patent:US2005/65130,2005,A1,.Locationinpatent:Page/Pagecolumn6
[1]Patent:CN111100084,2020,A.Locationinpatent:Paragraph0038-0045
[2]Patent:EP1550658,2005,A1.Locationinpatent:Page/Pagecolumn7
[3]SyntheticCommunications,2012,vol.42,p.639-649
[4]Patent:CN105726496,2019,B.Locationinpatent:Paragraph0054;0055;0056
[5]Patent:EP1223167,2002,A2.Locationinpatent:Page23
[6]JournalofMedicinalChemistry,2000,vol.43,p.775-777
[7]Patent:US2005/272787,2005,A1.Locationinpatent:Page/Pagecolumn2
[8]Patent:US2005/272787,2005,A1.Locationinpatent:Page/Pagecolumn2
[9]Patent:WO2005/123701,2005,A1.Locationinpatent:Page/Pagecolumn38-39
[10]Patent:WO2005/85218,2005,A1.Locationinpatent:Page/Pagecolumn10
[11]Patent:CN107137361,2017,A.Locationinpatent:Paragraph0031-0033
[1]JournalofMedicinalChemistry,2000,vol.43,p.1661-1663
[1]JournalofMedicinalChemistry,2000,vol.43,p.1661-1663
[1]Patent:CN110256370,2019,A.Locationinpatent:Paragraph0043;0048-0049;0052;0057-0058;0061;0066-0067
[2]Patent:CN105859647,2016,A.Locationinpatent:Paragraph0048;0049;0050
[3]Patent:CN106008387,2016,A.Locationinpatent:Paragraph0020;0048;0049;0050
[4]Patent:CN106008386,2016,A.Locationinpatent:Paragraph0021;0056;0057;0058
[5]Patent:CN111100084,2020,A.Locationinpatent:Paragraph0046-0053
[6]ChemicalCommunications,2019,vol.55,p.2027-2030
[7]Patent:CN105726496,2019,B.Locationinpatent:Paragraph0057;0058;0059
[8]JournalofMedicinalChemistry,2000,vol.43,p.1661-1663
[9]Patent:CN106674142,2017,A.Locationinpatent:Paragraph0038-0048
[10]Patent:WO2005/123701,2005,A1.Locationinpatent:Page/Pagecolumn39
[11]Patent:EP1550658,2005,A1.Locationinpatent:Page/Pagecolumn9
[12]Patent:US2003/232871,2003,A1.Locationinpatent:Page5
[13]Patent:CN104447600,2016,B.Locationinpatent:Paragraph0085;0088
[14]Patent:CN104193694,2016,B.Locationinpatent:Paragraph0036;0037
[15]Patent:CN107137361,2017,A.Locationinpatent:Paragraph0034-0035
[16]Patent:CN110305071,2019,A.Locationinpatent:Paragraph0027;0033-0047
[1]AdvancedSynthesisandCatalysis,2002,vol.344,p.1146-1151
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology 20150518
Title: Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101
Title: Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety.
Journal: Bioorganic & medicinal chemistry 20131001
Title: The effect of valdecoxib on the production of growth factors evoked by hypoxia and bacterial lipopolysaccharide in HMEC-1 cells.
Journal: Advances in clinical and experimental medicine : official organ Wroclaw Medical University 20130101
Title: Hypernociception and wound healing after application of cyanoacrylate ester as a tissue adhesive in rats.
Journal: Oral surgery, oral medicine, oral pathology and oral radiology 20121101
Title: Pain relief in laparoscopic cholecystectomy--a review of the current options.
Journal: Pain practice : the official journal of World Institute of Pain 20120701
Title: Pharmacokinetics of intravenous and intramuscular parecoxib in healthy Beagles.
Journal: Veterinary journal (London, England : 1997) 20120701
Title: Nonsteroidal anti-inflammatory drug-activated gene-1 plays a role in the impairing effects of cyclooxygenase inhibitors on gastric ulcer healing.
Journal: The Journal of pharmacology and experimental therapeutics 20120701
Title: Sulfonamides: a patent review (2008 - 2012).
Journal: Expert opinion on therapeutic patents 20120701
Title: A turbulent decade for NSAIDs: update on current concepts of classification, epidemiology, comparative efficacy, and toxicity.
Journal: Rheumatology international 20120601
Title: Development of a population pharmacokinetic model for parecoxib and its active metabolite valdecoxib after parenteral parecoxib administration in children.
Journal: Anesthesiology 20120501
Title: Nootropic activity of acetaminophen against colchicine induced cognitive impairment in rats.
Journal: Journal of clinical biochemistry and nutrition 20120501
Title: Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.
Journal: Journal of medicinal chemistry 20120412
Title: Transfer of parecoxib and its primary active metabolite valdecoxib via transitional breastmilk following intravenous parecoxib use after cesarean delivery: a comparison of naive pooled data analysis and nonlinear mixed-effects modeling.
Journal: Anesthesia and analgesia 20120401
Title: Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.
Journal: Journal of medicinal chemistry 20120308
Title: Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.
Journal: Bioorganic & medicinal chemistry 20120215
Title: Diagnosis and treatment of acute ankle injuries: development of an evidence-based algorithm.
Journal: Orthopedic reviews 20120102
Title: Aspirin: pharmacology and clinical applications.
Journal: Thrombosis 20120101
Title: Do nonsteroidal anti-inflammatory drugs affect bone healing? A critical analysis.
Journal: TheScientificWorldJournal 20120101
Title: Challenging medical ghostwriting in US courts.
Journal: PLoS medicine 20120101
Title: Evaluation of uptake and transport of cationic and anionic ultrasmall iron oxide nanoparticles by human colon cells.
Journal: International journal of nanomedicine 20120101
Title: Non-steroidal anti-inflammatory drugs for the treatment of pain and immobility-associated osteoarthritis: consensus guidance for primary care.
Journal: BMC family practice 20120101
Title: A randomized, placebo-controlled double-blinded comparative clinical study of five over-the-counter non-pharmacological topical analgesics for myofascial pain: single session findings.
Journal: Chiropractic & manual therapies 20120101
Title: Inhibition of ion channels and heart beat in Drosophila by selective COX-2 inhibitor SC-791.
Journal: PloS one 20120101
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways.
Journal: Chemical reviews 20111012
Title: Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Brain activity for chronic knee osteoarthritis: dissociating evoked pain from spontaneous pain.
Journal: European journal of pain (London, England) 20110901
Title: Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology.
Journal: Analytical and bioanalytical chemistry 20110901
Title: Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies.
Journal: PLoS medicine 20110901
Title: Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.
Journal: Bioorganic & medicinal chemistry 20110815
Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal: Journal of medicinal chemistry 20110714
Title: Defects in mouse nephrogenesis induced by selective and non-selective cyclooxygenase-2 inhibitors.
Journal: British journal of pharmacology 20110701
Title: 5-(3-Methyl-phen-yl)-3-phenyl-1,2-oxazole.
Journal: Acta crystallographica. Section E, Structure reports online 20110701
Title: Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601
Title: Synthesis and biological evaluation of loxoprofen derivatives.
Journal: Bioorganic & medicinal chemistry 20110601
Title: Iodocyclization of hydroxylamine derivatives based on the control of oxidative aromatization leading to 2,5-dihydroisoxazoles and isoxazoles.
Journal: The Journal of organic chemistry 20110506
Title: Strategies and practices in off-label marketing of pharmaceuticals: a retrospective analysis of whistleblower complaints.
Journal: PLoS medicine 20110401
Title: A randomized controlled trial of valdecoxib and glyceryl trinitrate for the prevention of post-ERCP pancreatitis.
Journal: Journal of clinical gastroenterology 20110201
Title: Selective cyclooxygenase-2 (COX-2) inhibitors and breast cancer risk.
Journal: Breast (Edinburgh, Scotland) 20110201
Title: A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.
Journal: Bioorganic & medicinal chemistry 20110201
Title: Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.
Journal: Bioorganic & medicinal chemistry letters 20110115
Title: A systematic review on the effectiveness of pharmacological interventions for chronic non-specific low-back pain.
Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20110101
Title: Parecoxib and its metabolite valdecoxib directly interact with cannabinoid binding sites in CB1-expressing HEK 293 cells and rat brain tissue.
Journal: Neurochemistry international 20110101
Title: Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis.
Journal: BMJ (Clinical research ed.) 20110101
Title: Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology.
Journal: Lipids in health and disease 20110101
Title: Methotrexate in atherogenesis and cholesterol metabolism.
Journal: Cholesterol 20110101
Title: Etoricoxibium picrate.
Journal: Acta crystallographica. Section E, Structure reports online 20110101
Title: Combined parecoxib and I.V. paracetamol provides additional analgesic effect with better postoperative satisfaction in patients undergoing anterior cruciate ligament reconstruction.
Journal: Saudi journal of anaesthesia 20110101
Title: Prostacyclin: an inflammatory paradox.
Journal: Frontiers in pharmacology 20110101
Title: The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres.
Journal: International journal of nanomedicine 20110101
Title: Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant.
Journal: Mediators of inflammation 20110101
Title: Bacterial carbonic anhydrases as drug targets: toward novel antibiotics?
Journal: Frontiers in pharmacology 20110101
Title: [Novel iodocyclization method based on the controlling of oxidative aromatization].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Title: Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents.
Journal: Scientia pharmaceutica 20110101
Title: Dissofilm: a novel approach for delivery of phenobarbital; design and characterization.
Journal: Journal of young pharmacists : JYP 20110101
Title: Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing.
Journal: Nutrition & metabolism 20110101
Title: Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y.
Journal: Chemistry Central journal 20110101
Title: Inhibition of HERG potassium channels by celecoxib and its mechanism.
Journal: PloS one 20110101
Title: Efficacy and Safety of COX-2 Inhibitors in the Clinical Management of Arthritis: Mini Review.
Journal: ISRN pharmacology 20110101
Title: Why we need easy access to all data from all clinical trials and how to accomplish it.
Journal: Trials 20110101
Title: An observational study of the discrediting of COX-2 NSAIDs in Australia: Vioxx or class effect?
Journal: BMC public health 20110101
Title: Virtual screening of 2,3-disubstituted-4(3H)-quinazolinones possessing benzenesulfonamide moiety for COX-2 inhibitor.
Journal: Bioinformation 20110101
Title: Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives.
Journal: Pharmacognosy reviews 20110101
Title: Autonomic status and pain profile in patients of chronic low back pain and following electro acupuncture therapy: a randomized control trial.
Journal: Indian journal of physiology and pharmacology 20110101
Title: Chronic inflammation in cancer development.
Journal: Frontiers in immunology 20110101
Title: Increased expression of cyclooxygenase-2 is associated with the progression to cirrhosis.
Journal: The Korean journal of internal medicine 20101201
Title: Reduction of N-hydroxy-sulfonamides, including N-hydroxy-valdecoxib, by the molybdenum-containing enzyme mARC.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101101
Title: Recent methodologies toward the synthesis of valdecoxib: a potential 3,4-diarylisoxazolyl COX-II inhibitor.
Journal: European journal of medicinal chemistry 20101101
Title: Enthalpy relaxation studies of two structurally related amorphous drugs and their binary dispersions.
Journal: Drug development and industrial pharmacy 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Does the use of non-steroidal anti-inflammatory drugs after cardiac surgery increase the risk of renal failure?
Journal: Interactive cardiovascular and thoracic surgery 20101001
Title: Does administration of non-steroidal anti-inflammatory drug determine morphological changes in adrenal cortex: ultrastructural studies.
Journal: Protoplasma 20101001
Title: Short-term treatment with COX-2 inhibitors does not impair fracture healing.
Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20101001
Title: Bitter pills for drug companies.
Journal: BMJ (Clinical research ed.) 20100917
Title: Eudragit S-100 entrapped chitosan microspheres of valdecoxib for colon cancer.
Journal: Journal of materials science. Materials in medicine 20100901
Title: Interventions for pain during fixed orthodontic appliance therapy. A systematic review.
Journal: The Angle orthodontist 20100901
Title: Loxoprofen Sodium, a Non-Selective NSAID, Reduces Atherosclerosis in Mice by Reducing Inflammation.
Journal: Journal of clinical biochemistry and nutrition 20100901
Title: Do the blood pressure effects of nonsteroidal antiinflammatory drugs influence cardiovascular morbidity and mortality?
Journal: Current hypertension reports 20100801
Title: tert-Butyl 3-(8-bromo-4H,10H-1,2-oxazolo[4,3-c][1]benzoxepin-10-yl)-2-methyl-1H-indole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online 20100801
Title: The COX-2 inhibitor parecoxib is neuroprotective but not antiepileptogenic in the pilocarpine model of temporal lobe epilepsy.
Journal: Experimental neurology 20100701
Title: Biotransformation of valdecoxib by microbial cultures.
Journal: Journal of microbiology and biotechnology 20100401
Title: Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.
Journal: Journal of medicinal chemistry 20100311
Title: Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.
Journal: Journal of medicinal chemistry 20100311
Title: Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review.
Journal: Health technology assessment (Winchester, England) 20100301
Title: Proteomic analysis in NSAIDs-treated primary cardiomyocytes.
Journal: Journal of proteomics 20100210
Title: Absorption and distribution of etoricoxib in plasma, CSF, and wound tissue in patients following hip surgery--a pilot study.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100201
Title: Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress.
Journal: Neuroscience bulletin 20100201
Title: [Selective inhibitors of cyclooxygenase-2 (COX-2), celecoxib and parecoxib: a systematic review].
Journal: Drugs of today (Barcelona, Spain : 1998) 20100201
Title: Progress in COX-2 inhibitors: a journey so far.
Journal: Current medicinal chemistry 20100101
Title: Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT.
Journal: PloS one 20100101
Title: Nonsteroidal Anti-Inflammatory Drugs: A survey of practices and concerns of pediatric medical and surgical specialists and a summary of available safety data.
Journal: Pediatric rheumatology online journal 20100101
Title: The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.
Journal: International journal of cell biology 20100101
Title: Traumeel S for pain relief following hallux valgus surgery: a randomized controlled trial.
Journal: BMC clinical pharmacology 20100101
Title: Reporting bias in medical research - a narrative review.
Journal: Trials 20100101
Title: Etoricoxib--preemptive and postoperative analgesia (EPPA) in patients with laparotomy or thoracotomy--design and protocols.
Journal: Trials 20100101
Title: Design of group IIA secreted/synovial phospholipase A(2) inhibitors: an oxadiazolone derivative suppresses chondrocyte prostaglandin E(2) secretion.
Journal: PloS one 20100101
Title: Preparation and evaluation of transdermal plasters containing norfloxacin: a novel treatment for burn wound healing.
Journal: Eplasty 20100101
Title: Role of COX-2 in cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome.
Journal: Cough (London, England) 20100101
Title: Clinical pharmacology and vascular risk.
Journal: The open neurology journal 20100101
Title: Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3.
Journal: Drug metabolism and pharmacokinetics 20100101
Title: Mathematical modeling of tuberculosis bacillary counts and cellular populations in the organs of infected mice.
Journal: PloS one 20100101
Title: Pharmacophore elucidation and molecular docking studies on 5-phenyl-1-(3-pyridyl)-1h-1,2,4-triazole-3-carboxylic acid derivatives as COX-2 inhibitors.
Journal: Scientia pharmaceutica 20100101
Title: Musculoskeletal pain: prescription of NSAID and weak opioid by primary health care physicians in Sweden 2004-2008 - a retrospective patient record review.
Journal: Journal of pain research 20100101
Title: Natural anti-inflammatory agents for pain relief.
Journal: Surgical neurology international 20100101
Title: COX-2 Inhibition by Use of Rofecoxib or High Dose Aspirin Enhances ADP-Induced Platelet Aggregation in Fresh Blood.
Journal: The open cardiovascular medicine journal 20100101
Title: Preparation and characterization of solid dispersions of carvedilol with PVP K30.
Journal: Research in pharmaceutical sciences 20100101
Title: Governance of conflicts of interest in postmarketing surveillance research and the Canadian Drug Safety and Effectiveness Network.
Journal: Open medicine : a peer-reviewed, independent, open-access journal 20100101
Title: Risk of Upper Gastrointestinal Bleeding in a Cohort of New Users of Low-Dose ASA for Secondary Prevention of Cardiovascular Outcomes.
Journal: Frontiers in pharmacology 20100101
Title: Analgesic, anticonvulsant and anti-inflammatory activities of some synthesized benzodiazipine, triazolopyrimidine and bis-imide derivatives.
Journal: European journal of medicinal chemistry 20091201
Title: NSAID switching and short-term gastrointestinal outcome rates after the withdrawal of rofecoxib.
Journal: Pharmacoepidemiology and drug safety 20091201
Title: Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.
Journal: Bioorganic & medicinal chemistry letters 20091201
Title: Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis.
Journal: Journal of hypertension 20091201
Title: A comparison of cost effectiveness using data from randomized trials or actual clinical practice: selective cox-2 inhibitors as an example.
Journal: PLoS medicine 20091201
Title: Non-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart disease.
Journal: Pharmacoepidemiology and drug safety 20091101
Title: Drug loaded poly[Lac(Glc-Leu)] microparticles: formulation and release characteristics.
Journal: Colloids and surfaces. B, Biointerfaces 20091101
Title: Parecoxib has non-significant long-term effects on bone healing in rats when administered for a short period after fracture.
Journal: Archives of orthopaedic and trauma surgery 20091001
Title: Cellular membranes function as a storage compartment for celecoxib.
Journal: Journal of molecular medicine (Berlin, Germany) 20091001
Title: Pharmacokinetics of intramuscular microparticle depot of valdecoxib in an experimental model.
Journal: Drug development and industrial pharmacy 20090901
Title: The search for new COX-2 inhibitors: a review of 2002 - 2008 patents.
Journal: Expert opinion on therapeutic patents 20090901
Title: Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study.
Journal: Clinical rheumatology 20090801
Title: Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: The regulatory effect of the p38 signaling pathway on valdecoxib-induced apoptosis of the Eca109 cell line.
Journal: Oncology reports 20090801
Title: Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.
Journal: Bioorganic & medicinal chemistry 20090715
Title: Prolonged opportunity for neuroprotection in experimental stroke with selective blockade of cyclooxygenase-2 activity.
Journal: Brain research 20090707
Title: Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.
Journal: Bioorganic & medicinal chemistry 20090701
Title: Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome.
Journal: PLoS computational biology 20090701
Title: Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?
Journal: Expert opinion on drug metabolism & toxicology 20090601
Title: Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.
Journal: Journal of medicinal chemistry 20090514
Title: Effects of cyclooxygenase inhibition on anastomotic healing following large bowel resection in a rabbit model--a randomized, blinded, placebo-controlled trial.
Journal: International journal of colorectal disease 20090501
Title: Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.
Journal: Journal of medicinal chemistry 20090423
Title: Validation of single isocratic HPLC method for the assay of valdecoxib and determination of metaisomer impurity.
Journal: Journal of chromatographic science 20090401
Title: Non-steroidal anti-inflammatory drug use does not appear to be associated with increased cardiovascular mortality in patients with inflammatory polyarthritis: results from a primary care based inception cohort of patients.
Journal: Annals of the rheumatic diseases 20090301
Title: Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.
Journal: Bioorganic & medicinal chemistry 20090201
Title: Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting: an analysis of integrated data.
Journal: Anesthesia and analgesia 20090101
Title: A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritis.
Journal: Osteopathic medicine and primary care 20090101
Title: A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis: a randomised, placebo controlled pilot study.
Journal: Nutrition journal 20090101
Title: Complexation of cox-2 inhibitors with bovine serum albumin: interaction mechanism.
Journal: Pharmaceutical development and technology 20090101
Title: Information about ADRs explored by pharmacovigilance approaches: a qualitative review of studies on antibiotics, SSRIs and NSAIDs.
Journal: BMC clinical pharmacology 20090101
Title: Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models.
Journal: Arthritis research & therapy 20090101
Title: Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship.
Journal: PloS one 20090101
Title: Competition between COX-2 inhibitors and some other drugs for binding sites on human serum albumin.
Journal: Drug metabolism and drug interactions 20090101
Title: Prophylaxis of heterotopic ossification - an updated review.
Journal: Journal of orthopaedic surgery and research 20090101
Title: Treatment and chemoprevention of NSAID-associated gastrointestinal complications.
Journal: Therapeutics and clinical risk management 20090101
Title: Twelve years' experience with direct-to-consumer advertising of prescription drugs in Canada: a cautionary tale.
Journal: PloS one 20090101
Title: Development of mucoadhesive buccal films for the treatment of oral sub-mucous fibrosis: a preliminary study.
Journal: Pharmaceutical development and technology 20090101
Title: Discrepancy among observational studies: example of naproxen-associated adverse events.
Journal: The open rheumatology journal 20090101
Title: Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis.
Journal: BMJ (Clinical research ed.) 20090101
Title: Reduction in opioid-related adverse events and improvement in function with parecoxib followed by valdecoxib treatment after non-cardiac surgery: a randomized, double-blind, placebo-controlled, parallel-group trial.
Journal: Clinical drug investigation 20090101
Title: Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: implications for diagnosis and monitoring drug therapy.
Journal: PloS one 20090101
Title: Identification of the specific binding proteins of bioactive small compound using affinity resins.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: Celecoxib in arthritis: relative risk management profile and implications for patients.
Journal: Therapeutics and clinical risk management 20090101
Title: Drug-induced hematologic syndromes.
Journal: Advances in hematology 20090101
Title: Prevention of NSAID-related upper gastrointestinal toxicity: a meta-analysis of traditional NSAIDs with gastroprotection and COX-2 inhibitors.
Journal: Drug, healthcare and patient safety 20090101
Title: Co-relationship of physical stability of amorphous dispersions with enthalpy relaxation.
Journal: Die Pharmazie 20081101
Title: Hospitalization for peptic ulcer and bleeding in users of selective COX-2 inhibitors and nonselective NSAIDs with special reference to celecoxib.
Journal: Pharmacoepidemiology and drug safety 20081001
Title: Risk management profile of etoricoxib: an example of personalized medicine.
Journal: Therapeutics and clinical risk management 20081001
Title: Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity.
Journal: Journal of medicinal chemistry 20080814
Title: Thermodynamic behavior of glassy state of structurally related compounds.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080801
Title: Can drug removals involving cyclooxygenase-2 inhibitors be avoided? A plea for human pharmacology.
Journal: Trends in pharmacological sciences 20080801
Title: A postgenomic integrated view of prostaglandins in reproduction: implications for other body systems.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801
Title: Cardiovascular and gastrointestinal toxicity of selective cyclo-oxygenase-2 inhibitors in man.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801
Title: The anti-proliferative potency of celecoxib is not a class effect of coxibs.
Journal: Biochemical pharmacology 20080715
Title: [American judge preserves confidentiality in the peer review process].
Journal: Nederlands tijdschrift voor geneeskunde 20080712
Title: Nonaspirin NSAIDs, cyclooxygenase 2 inhibitors, and the risk for stroke.
Journal: Stroke 20080701
Title: Effects of a non-selective COX inhibitor and selective COX-2 inhibitors on contractility of human and porcine ureters in vitro and in vivo.
Journal: British journal of pharmacology 20080701
Title: Comparison of parecoxib and proparacetamol in endoscopic nasal surgery patients.
Journal: Yonsei medical journal 20080630
Title: Modeling and simulation to support dose selection and clinical development of SC-75416, a selective COX-2 inhibitor for the treatment of acute and chronic pain.
Journal: Clinical pharmacology and therapeutics 20080601
Title: Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of zafirlukast, a selective leukotriene antagonist in human plasma: application to a clinical pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20080601
Title: Risk of ischaemic cardiovascular events from selective cyclooxygenase-2 inhibitors in osteoarthritis.
Journal: Pharmacoepidemiology and drug safety 20080601
Title: Multimodal analgesia without parenteral narcotics for total knee arthroplasty.
Journal: The Journal of arthroplasty 20080601
Title: Pharmaceutical particle engineering via spray drying.
Journal: Pharmaceutical research 20080501
Title: Chemical and biological investigation of N-hydroxy-valdecoxib: An active metabolite of valdecoxib.
Journal: Bioorganic & medicinal chemistry 20080501
Title: Effect of paracetamol and coxib with or without dexamethasone after laparoscopic cholecystectomy.
Journal: Acta anaesthesiologica Scandinavica 20080501
Title: Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition.
Journal: Circulation research 20080425
Title: Preserving confidentiality in the peer review process.
Journal: JAMA 20080423
Title: Computer-aided, rational design of a potent and selective small peptide inhibitor of cyclooxygenase 2 (COX2).
Journal: Journal of biomolecular structure & dynamics 20080401
Title: Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation.
Journal: Health technology assessment (Winchester, England) 20080401
Title: Efficacy and tolerability of lumiracoxib, a highly selective cyclo-oxygenase-2 (COX2) inhibitor, in the management of pain and osteoarthritis.
Journal: Therapeutics and clinical risk management 20080401
Title: Crunch time for peer review in lawsuit.
Journal: Nature 20080306
Title: Intravenous parecoxib rapidly leads to COX-2 inhibitory concentration of valdecoxib in the central nervous system.
Journal: Clinical pharmacology and therapeutics 20080301
Title: Anti-inflammatory and analgesic activities of newly synthesized chiral peptide derivatives using (3-benzoyl- 4,5-dioxo-2-phenyl-pyrrolidin-1-yl)acetic acid ethyl ester as starting material.
Journal: Archiv der Pharmazie 20080301
Title: Informatic tools and approaches in postmarketing pharmacovigilance used by FDA.
Journal: The AAPS journal 20080301
Title: Biotransformation of valdecoxib by plant cell cultures.
Journal: Applied biochemistry and biotechnology 20080301
Title: Inhibition of delayed rectifier potassium channels and induction of arrhythmia: a novel effect of celecoxib and the mechanism underlying it.
Journal: The Journal of biological chemistry 20080118
Title: Celecoxib transiently inhibits cellular protein synthesis.
Journal: Biochemical pharmacology 20080115
Title: New celecoxib derivatives as anti-inflammatory agents.
Journal: Journal of medicinal chemistry 20080110
Title: Preclinical pharmacology profile of CS-706, a novel cyclooxygenase-2 selective inhibitor, with potent antinociceptive and anti-inflammatory effects.
Journal: European journal of pharmacology 20080106
Title: Effects of nonsteroidal anti-inflammatory drugs on the expression of urokinase plasminogen activator and inhibitor and gelatinases in the early osteoarthritic knee of humans.
Journal: Clinical biochemistry 20080101
Title: Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs.
Journal: Expert opinion on drug safety 20080101
Title: Etoricoxib-induced erythema-multiforme-like eruption.
Journal: Dermatology (Basel, Switzerland) 20080101
Title: Use of cox-2 inhibitors in patients with retinal venous occlusive disease.
Journal: Retina (Philadelphia, Pa.) 20080101
Title: Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes.
Journal: Arthritis research & therapy 20080101
Title: What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs.
Journal: Arthritis research & therapy 20080101
Title: OTC analgesics and drug interactions: clinical implications.
Journal: Osteopathic medicine and primary care 20080101
Title: A natural mineral supplement provides relief from knee osteoarthritis symptoms: a randomized controlled pilot trial.
Journal: Nutrition journal 20080101
Title: Long-term retention on treatment with lumiracoxib 100 mg once or twice daily compared with celecoxib 200 mg once daily: a randomised controlled trial in patients with osteoarthritis.
Journal: BMC musculoskeletal disorders 20080101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20080101
Title: Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection.
Journal: PloS one 20080101
Title: Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports.
Journal: Arthritis research & therapy 20080101
Title: Patients with rheumatoid arthritis have an altered circulatory aggrecan profile.
Journal: BMC musculoskeletal disorders 20080101
Title: Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
Journal: BMC musculoskeletal disorders 20080101
Title: Peroxisome proliferator-activated receptors and progression of colorectal cancer.
Journal: PPAR research 20080101
Title: Virtual screening for novel COX-2 inhibitors using the ZINC database.
Journal: Bioinformation 20080101
Title: Similar reductions in the risk of human colon cancer by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors.
Journal: BMC cancer 20080101
Title: Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis.
Journal: Arthritis research & therapy 20080101
Title: Role of nitric oxide in the gastrointestinal tract.
Journal: Arthritis research & therapy 20080101
Title: Frankincense: systematic review.
Journal: BMJ (Clinical research ed.) 20080101
Title: PPAR-delta in Vascular Pathophysiology.
Journal: PPAR research 20080101
Title: [Cardiovascular risk of cyclooxygenase selective inhibitors].
Journal: Revista medica del Instituto Mexicano del Seguro Social 20080101
Title: Combination Therapy of PPARgamma Ligands and Inhibitors of Arachidonic Acid in Lung Cancer.
Journal: PPAR research 20080101
Title: FTIR studies on differential intermolecular association in crystalline and amorphous states of structurally related non-steroidal anti-inflammatory drugs.
Journal: Molecular pharmaceutics 20080101
Title: Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: An overview of the articles published in the Indian Journal of Pharmacology during the year 2007.
Journal: Indian journal of pharmacology 20080101
Title: The synthesis of highly substituted isoxazoles by electrophilic cyclization: an efficient synthesis of valdecoxib.
Journal: The Journal of organic chemistry 20071207
Title: Direct non-cyclooxygenase-2 targets of celecoxib and their potential relevance for cancer therapy.
Journal: British journal of cancer 20071203
Title: Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.
Journal: Bioorganic & medicinal chemistry 20071201
Title: Early detection of adverse drug events within population-based health networks: application of sequential testing methods.
Journal: Pharmacoepidemiology and drug safety 20071201
Title: NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20071201
Title: COX-2 inhibitors and postoperative ileus.
Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20071101
Title: Roles of vasoconstrictor prostaglandins, COX-1 and -2, and AT1, AT2, and TP receptors in a rat model of early 2K,1C hypertension.
Journal: American journal of physiology. Heart and circulatory physiology 20071101
Title: Cardiovascular effects of cyclooxygenase-2 inhibitors.
Journal: Current opinion in gastroenterology 20071101
Title: Successful treatment of cystoid macular edema with valdecoxib.
Journal: Journal of cataract and refractive surgery 20071101
Title: Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001
Title: Drug insight: cyclo-oxygenase-2 inhibitors--a critical appraisal.
Journal: Nature clinical practice. Rheumatology 20071001
Title: Selective COX-2 inhibitors, NSAIDs and cardiovascular events - is celecoxib the safest choice?
Journal: Therapeutics and clinical risk management 20071001
Title: The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs.
Journal: Journal of molecular medicine (Berlin, Germany) 20070901
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20070901
Title: The effects of common anti-inflammatory drugs on the healing rat patellar tendon.
Journal: The American journal of sports medicine 20070801
Title: Withdrawal of COX-2 selective inhibitors rofecoxib and valdecoxib: impact on NSAID and gastroprotective drug prescribing and utilization.
Journal: Current medical research and opinion 20070801
Title: The selective and non-selective cyclooxygenase inhibitors valdecoxib and piroxicam induce the same postoperative analgesia and control of trismus and swelling after lower third molar removal.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070801
Title: Clinical pharmacology of celecoxib, a COX-2 selective inhibitor.
Journal: Expert opinion on pharmacotherapy 20070801
Title: Gastrointestinal safety of novel nonsteroidal antiinflammatory drugs: selective COX-2 inhibitors and beyond.
Journal: Acta bio-medica : Atenei Parmensis 20070801
Title: Celecoxib dilates guinea-pig coronaries and rat aortic rings and amplifies NO/cGMP signaling by PDE5 inhibition.
Journal: Cardiovascular research 20070715
Title: Risk of myocardial infarction associated with selective COX-2 inhibitors: meta-analysis of randomised controlled trials.
Journal: Pharmacoepidemiology and drug safety 20070701
Title: Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs): a systematic structured review of the literature.
Journal: Archives of dermatological research 20070701
Title: Utility and sensitivity of the sore throat pain model: results of a randomized controlled trial on the COX-2 selective inhibitor valdecoxib.
Journal: Journal of clinical pharmacology 20070701
Title: Gastrointestinal safety of cyclooxygenase-2 inhibitors: a Cochrane Collaboration systematic review.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070701
Title: [Cardiovascular toxicity of selective COX-2-inhibitors and classical NSAIDs].
Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20070701
Title: Polyamines in inflammation and their modulation by conventional anti-inflammatory drugs.
Journal: Indian journal of experimental biology 20070701
Title: Topical dosage form of valdecoxib: preparation and pharmacological evaluation.
Journal: Acta pharmaceutica (Zagreb, Croatia) 20070601
Title: Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms.
Journal: Fundamental & clinical pharmacology 20070601
Title: Preliminary development of a responder index for chronic low back pain.
Journal: The Journal of rheumatology 20070601
Title: Multimodal analgesia for radical prostatectomy provides better analgesia and shortens hospital stay.
Journal: Journal of clinical anesthesia 20070601
Title: Cutaneous adverse reactions to valdecoxib distinct from Stevens-Johnson syndrome and toxic epidermal necrolysis.
Journal: Archives of dermatology 20070601
Title: Efficacy and tolerability of valdecoxib in treating the signs and symptoms of severe rheumatoid arthritis: a 12-week, multicenter, randomized, double-blind, placebo-controlled study.
Journal: Clinical therapeutics 20070601
Title: Current aproach to cancer pain management: Availability and implications of different treatment options.
Journal: Therapeutics and clinical risk management 20070601
Title: Targeting inhibition of COX-2: a review of patents, 2002-2006.
Journal: Recent patents on inflammation & allergy drug discovery 20070601
Title: Successful treatment of cystoid macular edema with valdecoxib.
Journal: Journal of cataract and refractive surgery 20070401
Title: Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib.
Journal: Molecular cancer therapeutics 20070401
Title: Cyclooxygenase-2 inhibition increases gastric tone and delays gastric emptying in rats.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070301
Title: Dynamic simulations on the arachidonic acid metabolic network.
Journal: PLoS computational biology 20070301
Title: Cyclooxygenase inhibition and adverse remodeling during healing after myocardial infarction.
Journal: Circulation 20070123
Title: Pharmacodynamic of cyclooxygenase inhibitors in humans.
Journal: Prostaglandins & other lipid mediators 20070101
Title: Prospective randomized, double-blind, placebo-controlled study of pre- and postoperative administration of a COX-2-specific inhibitor as opioid-sparing analgesia in major colorectal surgery.
Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20070101
Title: Safety of parecoxib and valdecoxib after noncardiac surgery: lack of demonstration.
Journal: Anesthesiology 20070101
Title: Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment.
Journal: The Journal of bone and joint surgery. American volume 20070101
Title: Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular risk.
Journal: Arthritis research & therapy 20070101
Title: Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers.
Journal: Current topics in medicinal chemistry 20070101
Title: Valdecoxib is as efficacious as diclofenac in the treatment of acute low back pain.
Journal: The Clinical journal of pain 20070101
Title: Dual carbonic anhydrase--cyclooxygenase-2 inhibitors.
Journal: Current topics in medicinal chemistry 20070101
Title: New dosage formulations for targeted delivery of cyclo-oxygenase-2 inhibitors: focus on use in the elderly.
Journal: Drugs & aging 20070101
Title: Reduced risk of human lung cancer by selective cyclooxygenase 2 (COX-2) blockade: results of a case control study.
Journal: International journal of biological sciences 20070101
Title: COX-2 inhibitors and cardiovascular risk.
Journal: Sub-cellular biochemistry 20070101
Title: Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk.
Journal: BMC musculoskeletal disorders 20070101
Title: Atypical antipsychotics in bipolar disorder: systematic review of randomised trials.
Journal: BMC psychiatry 20070101
Title: Preparation and properties of valdecoxib-hydroxypropyl beta-cyclodextrin inclusion complex.
Journal: PDA journal of pharmaceutical science and technology 20070101
Title: The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction.
Journal: PloS one 20070101
Title: Molecular and thermodynamic aspects of solubility advantage from solid dispersions.
Journal: Molecular pharmaceutics 20070101
Title: An effective dose of valdecoxib in experimental mouse models of pain.
Journal: Methods and findings in experimental and clinical pharmacology 20070101
Title: Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts.
Journal: Arthritis research & therapy 20070101
Title: Multi-modal-analgesia for pain management after Hallux Valgus surgery: a prospective randomised study on the effect of ankle block.
Journal: Journal of orthopaedic surgery and research 20070101
Title: Protective effect of non-selective and selective COX-2-inhibitors in acute immobilization stress-induced behavioral and biochemical alterations.
Journal: Pharmacological reports : PR 20070101
Title: Computer aided drug design approaches to develop cyclooxygenase based novel anti-inflammatory and anti-cancer drugs.
Journal: Current pharmaceutical design 20070101
Title: Lumiracoxib: the evidence of its clinical impact on the treatment of osteoarthritis.
Journal: Core evidence 20070101
Title: Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats.
Journal: European journal of pharmacology 20061203
Title: Use of cyclo-oxygenase 2 inhibitors (COX-2) and prescription non-steroidal anti-inflammatory drugs (NSAIDS) in UK and USA populations. Implications for COX-2 cardiovascular profile.
Journal: Pharmacoepidemiology and drug safety 20061201
Title: Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials.
Journal: Journal of clinical pharmacy and therapeutics 20061201
Title: An analgesic model for assessment of acute pain response in osteoarthritis of the knee.
Journal: Osteoarthritis and cartilage 20061101
Title: Cardiovascular and cerebrovascular events in the randomized, controlled Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT).
Journal: PLoS clinical trials 20061101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20061101
Title: Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: meta-analysis of randomized trials.
Journal: JAMA 20061004
Title: [Analgesia in colon surgery. Can the use of NSAIDs reduce the opioid consumption following conventional and laparoscopic interventions?].
Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20061001
Title: Prescribing of COX-2 inhibitors in Germany after safety warnings and market withdrawals.
Journal: Die Pharmazie 20061001
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20061001
Title: Trying times for painkiller choices. Vioxx, Bextra, and Celebrex can increase the risk for heart attack and other cardiovascular problems. So can the old standbys, like ibuprofen and acetaminophen.
Journal: Harvard heart letter : from Harvard Medical School 20061001
Title: Valdecoxib for postoperative pain management after cesarean delivery: a randomized, double-blind, placebo-controlled study.
Journal: Anesthesia and analgesia 20060901
Title: Formulation and evaluation of Nanostructured Lipid Carrier (NLC)-based gel of Valdecoxib.
Journal: Drug development and industrial pharmacy 20060901
Title: Valdecoxib does not interfere with the CYP2D6 substrate metoprolol.
Journal: International journal of clinical pharmacology and therapeutics 20060901
Title: Impact of cyclooxygenase inhibitors in the Women's Health Initiative hormone trials: secondary analysis of a randomized trial.
Journal: PLoS clinical trials 20060901
Title: Enhancement of dissolution profile by solid dispersion (kneading) technique.
Journal: AAPS PharmSciTech 20060901
Title: [What do we know about the cardiovascular toxicity of the NSAIDs?].
Journal: Presse medicale (Paris, France : 1983) 20060901
Title: [Are there any differences in the cardiovascular tolerance between classical NSAIDs and coxibs?].
Journal: Presse medicale (Paris, France : 1983) 20060901
Title: Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease.
Journal: Vascular health and risk management 20060901
Title: [Are there any differences in the cardiovascular tolerance between classical NSAIDs and coxibs?].
Journal: Presse medicale (Paris, France : 1983) 20060901
Title: Augmentation of myocardial production of 15-epi-lipoxin-a4 by pioglitazone and atorvastatin in the rat.
Journal: Circulation 20060829
Title: COX-2 inhibitors and early failure of free vascular flaps.
Journal: The New England journal of medicine 20060803
Title: Constitutive cyclo-oxygenase-2 does not contribute to the development of human visceral pain hypersensitivity.
Journal: European journal of pain (London, England) 20060801
Title: Reversible binding of celecoxib and valdecoxib with human serum albumin using fluorescence spectroscopic technique.
Journal: Pharmacological research 20060801
Title: Selective cyclooxygenase inhibition: its role in pain and anaesthesia.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20060801
Title: The COX-2 inhibitors--an update.
Journal: American heart journal 20060801
Title: Preparation, characterization and in vitro dissolution studies of solid systems of valdecoxib with chitosan.
Journal: Chemical & pharmaceutical bulletin 20060801
Title: How specific are 'target-specific' drugs? Celecoxib as a case in point.
Journal: Molecular interventions 20060801
Title: NSAID use and the risk of hospitalization for first myocardial infarction in the general population: a nationwide case-control study from Finland.
Journal: European heart journal 20060701
Title: Forced-degradation study of valdecoxib as bulk drug and in tablet formulation by HPTLC.
Journal: Journal of separation science 20060701
Title: [Cyclooxygenase inhibitors: a never ending story?].
Journal: Giornale italiano di cardiologia (2006) 20060701
Title: Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Journal: Clinical therapeutics 20060701
Title: The COX-2 specific inhibitor Valdecoxib versus tramadol in acute ankle sprain: a multicenter randomized, controlled trial.
Journal: The American journal of sports medicine 20060601
Title: Getting it right: being smarter about clinical trials.
Journal: PLoS medicine 20060601
Title: Efficacy of a selective COX-2 inhibitor for controlling irregular uterine bleeding in DMPA users.
Journal: Contraception 20060601
Title: Synthesis of the pyrazole isostere of valdecoxib.
Journal: Die Pharmazie 20060601
Title: [Cyclooxygenase-2: a new therapeutic target in atherosclerosis?].
Journal: Medicina clinica 20060527
Title: Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.
Journal: European journal of pharmacology 20060501
Title: Update on nonsteriodal anti-inflammatory drugs.
Journal: Current opinion in rheumatology 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs: high-risk subgroups and time course of risk.
Journal: Arthritis and rheumatism 20060501
Title: Valdecoxib exposures reported to Texas poison centers during 2002-2004.
Journal: Journal of toxicology and environmental health. Part A 20060501
Title: Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction.
Journal: Circulation 20060425
Title: COX-2 inhibitors and pain after oral surgery - pertinent papers 2002-2003.
Journal: The British journal of oral & maxillofacial surgery 20060401
Title: Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity.
Journal: Biochemistry 20060314
Title: Safety and efficacy of the cyclooxygenase-2 inhibitors parecoxib and valdecoxib after noncardiac surgery.
Journal: Anesthesiology 20060301
Title: Evaluation of preemptive valdecoxib therapy on initial archwire placement discomfort in adults.
Journal: The Angle orthodontist 20060301
Title: Determination of valdecoxib in serum using a HPLC-diode array detector and its application in a pharmacokinetic study.
Journal: Die Pharmazie 20060301
Title: A multicenter, randomized, double-blind, active-comparator, placebo-controlled, parallel-group comparison of the incidence of endoscopic gastric and duodenal ulcer rates with valdecoxib or naproxen in healthy subjects aged 65 to 75 years.
Journal: Clinical therapeutics 20060301
Title: Etoricoxib for arthritis and pain management.
Journal: Therapeutics and clinical risk management 20060301
Title: COX inhibitors and breast cancer.
Journal: British journal of cancer 20060213
Title: Ocular adverse effects associated with cyclooxygenase-2 inhibitors.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20060201
Title: A comparison of valdecoxib and naproxen in the treatment of rheumatoid arthritis symptoms.
Journal: Clinical therapeutics 20060201
Title: Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II 'selective' inhibitor celecoxib.
Journal: Bioorganic & medicinal chemistry letters 20060115
Title: Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by high-performance liquid chromatography with UV detection.
Journal: Biomedical chromatography : BMC 20060101
Title: Systematic review: coxibs, non-steroidal anti-inflammatory drugs or no cyclooxygenase inhibitors in gastroenterological high-risk patients?
Journal: Alimentary pharmacology & therapeutics 20060101
Title: Spray dried excipient base: a novel technique for the formulation of orally disintegrating tablets.
Journal: Chemical & pharmaceutical bulletin 20060101
Title: Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors.
Journal: BMC cancer 20060101
Title: NSAID-associated adverse effects and acid control aids to prevent them: a review of current treatment options.
Journal: Drug safety 20060101
Title: First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215].
Journal: Arthritis research & therapy 20060101
Title: Effect of valdecoxib pretreatment on pain and secondary hyperalgesia: a randomized controlled trial in healthy volunteers [ISRCTN05282752, NCT00260325].
Journal: BMC anesthesiology 20060101
Title: Coxibs and cardiovascular side-effects: from light to shadow.
Journal: Current pharmaceutical design 20060101
Title: Do coxibs reduce prescription of gastroprotective agents? Results of a record linkage study.
Journal: Cost effectiveness and resource allocation : C/E 20060101
Title: Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.
Journal: Journal of neuroinflammation 20060101
Title: Cyclooxygenase expression is not required for release of arachidonic acid from cells by some nonsteroidal anti-inflammatory drugs and cancer preventive agents.
Journal: BMC pharmacology 20060101
Title: Disseminating drug prescribing information: the cox-2 inhibitors withdrawals.
Journal: Journal of the American Medical Informatics Association : JAMIA 20060101
Title: Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.
Journal: Molecular cancer 20060101
Title: Update on guidelines for the treatment of chronic musculoskeletal pain.
Journal: Clinical rheumatology 20060101
Title: Rofecoxib increases susceptibility of human LDL and membrane lipids to oxidative damage: a mechanism of cardiotoxicity.
Journal: Journal of cardiovascular pharmacology 20060101
Title: Unmet needs in non-steroidal anti-inflammatory drug-induced upper gastrointestinal diseases.
Journal: Drugs 20060101
Title: Serious skin reactions and selective COX-2 inhibitors: a case series from prescription-event monitoring in England.
Journal: Drug safety 20060101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20060101
Title: Analgesic efficacy of valdecoxib for acute postoperative pain after bunionectomy.
Journal: Journal of the American Podiatric Medical Association 20060101
Title: Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis.
Journal: Arthritis research & therapy 20060101
Title: Responding rapidly to FDA drug withdrawals: design and application of a new approach for a consumer health website.
Journal: Journal of medical Internet research 20060101
Title: Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice.
Journal: BMC musculoskeletal disorders 20060101
Title: Impact of rofecoxib withdrawal on cyclooxygenase-2 utilization among patients with and without cardiovascular risk.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20060101
Title: Valdecoxib provides effective pain relief following acute ankle sprain.
Journal: The Journal of international medical research 20060101
Title: Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?
Journal: Journal of neuroinflammation 20060101
Title: A case of intranasal meningocele.
Journal: McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20060101
Title: What clinical pharmacology means to us.
Journal: Mens sana monographs 20060101
Title: Topical analgesia for chest tube removal in cardiac patients.
Journal: Journal of cardiothoracic and vascular anesthesia 20051201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20051201
Title: More bad news about anti-inflammatory agents.
Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20051201
Title: Increased risk of cardiovascular events with parecoxib/valdecoxib: a systematic review and meta-analysis.
Journal: The New Zealand medical journal 20051125
Title: Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same?
Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101
Title: Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography.
Journal: Bioorganic & medicinal chemistry letters 20051101
Title: Celecoxib and cardiovascular risks.
Journal: Expert opinion on drug safety 20051101
Title: COX-2 inhibitors and the heart: putting risk in perspective.
Journal: Advance for nurse practitioners 20051101
Title: Cardiovascular issues of COX-2 inhibitors and NSAIDs.
Journal: Australian family physician 20051101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20051101
Title: [Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs)].
Journal: Deutsche medizinische Wochenschrift (1946) 20051007
Title: Cancer chemoprevention: lessons learned and future directions.
Journal: British journal of cancer 20051003
Title: Valdecoxib for treatment of a single, acute, moderate to severe migraine headache.
Journal: Headache 20051001
Title: Prescriptions for chronic high-dose cyclooxygenase-2 inhibitors are often inappropriate and potentially dangerous.
Journal: Journal of general internal medicine 20051001
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20051001
Title: How celecoxib could be safer, how valdecoxib might have been.
Journal: The Annals of pharmacotherapy 20050901
Title: Synthesis and reactions of some new substituted pyridine and pyrimidine derivatives as analgesic, anticonvulsant and antiparkinsonian agents.
Journal: Archiv der Pharmazie 20050901
Title: Nonsteroidal anti-inflammatory drugs: confusion, controversy and dental implications.
Journal: Journal (Canadian Dental Association) 20050901
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050901
Title: COX-2 inhibition and pain management: a review summary.
Journal: Expert review of clinical immunology 20050901
Title: Need for common internal controls when assessing the relative efficacy of pharmacologic agents using a meta-analytic approach: case study of cyclooxygenase 2-selective inhibitors for the treatment of osteoarthritis.
Journal: Arthritis and rheumatism 20050815
Title: Update on cyclooxygenase inhibitors: has a third COX isoform entered the fray?
Journal: Current medical research and opinion 20050801
Title: Monocyte cyclooxygenase-2 activity: a new therapeutic target for atherosclerosis?
Journal: Current drug targets. Cardiovascular & haematological disorders 20050801
Title: Further action taken on COX 2 inhibitors in Europe.
Journal: BMJ (Clinical research ed.) 20050702
Title: Pulmonary embolism in a woman taking oral contraceptives and valdecoxib.
Journal: PLoS medicine 20050701
Title: Cyclooxygenase-2 inhibitors: a new therapeutic option in the treatment of macular edema after cataract surgery.
Journal: Journal of cataract and refractive surgery 20050701
Title: An evaluation of preemptive valdecoxib therapy on discomfort caused by initial archwire placement in adult orthodontic patients.
Journal: Texas dental journal 20050701
Title: Effect of selective cyclooxygenase-2 inhibitors on heart rate in healthy young men.
Journal: The American journal of cardiology 20050615
Title: Development and validation of a reversed-phase liquid chromatographic method for separation and simultaneous determination of COX-2 inhibitors in pharmaceuticals and its application to biological fluids.
Journal: Biomedical chromatography : BMC 20050601
Title: The effect of mild and moderate hepatic impairment on the pharmacokinetics of valdecoxib, a selective COX-2 inhibitor.
Journal: European journal of clinical pharmacology 20050601
Title: Rescuing COX-2 inhibitors from the waste bin.
Journal: Journal of the National Cancer Institute 20050601
Title: Valdecoxib withdrawal leaves pain relief treatment gap.
Journal: Gastroenterology 20050601
Title: The meaning of pain relief in a clinical trial.
Journal: The journal of pain : official journal of the American Pain Society 20050601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050601
Title: Molecular mechanisms responsible for the antiinflammatory and protective effect of HDL on the endothelium.
Journal: Vascular health and risk management 20050601
Title: FDA ponders future of NSAIDs: Pfizer reluctantly withdraws Bextra.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050515
Title: New restrictions on celecoxib (Celebrex) use and the withdrawal of valdecoxib (Bextra).
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050510
Title: Valdecoxib-associated acute generalized exanthematous pustulosis.
Journal: Burns : journal of the International Society for Burn Injuries 20050501
Title: Vioxx, Celebrex, Bextra....do we have a new target for anti-inflammatory and antipyretic therapy?
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050501
Title: Valdecoxib is associated with improved dyspepsia-related health compared with nonspecific NSAIDs in patients with osteoarthritis or rheumatoid arthritis.
Journal: The American journal of gastroenterology 20050501
Title: Cyclodextrin complexes of valdecoxib: properties and anti-inflammatory activity in rat.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050501
Title: COX-2-selective inhibitor valdecoxib induces severe allergic skin reactions.
Journal: The Journal of allergy and clinical immunology 20050501
Title: Nonsteroidal anti-inflammatory drugs and hepatic toxicity: a systematic review of randomized controlled trials in arthritis patients.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20050501
Title: [Cardiovascular risks of Cox-2-antagonists. Opinion on the marketed name rofecoxib, and its market-withdrawn valdecoxib and the actual therapeutic restrictions].
Journal: Zeitschrift fur Rheumatologie 20050501
Title: Pfizer withdraws Bextra in South Africa.
Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20050501
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050501
Title: Researchers plan to continue to study COX-2 inhibitors in cancer treatment and prevention.
Journal: Journal of the National Cancer Institute 20050420
Title: Another popular painkiller gets the government's hook.
Journal: U.S. news & world report 20050418
Title: Pfizer is asked to suspend sales of painkiller.
Journal: BMJ (Clinical research ed.) 20050416
Title: [COX-2 inhibitors--one step forward and two steps back].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050407
Title: Exacerbation of carpal tunnel syndrome under treatment with valdecoxib.
Journal: Anesthesia and analgesia 20050401
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050401
Title: Valdecoxib: cutaneous and vascular risks.
Journal: Prescrire international 20050401
Title: Clinical pharmacology of lumiracoxib, a second-generation cyclooxygenase 2 selective inhibitor.
Journal: Expert opinion on investigational drugs 20050401
Title: Raising the safety bar--the FDA's coxib meeting.
Journal: The New England journal of medicine 20050331
Title: Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery.
Journal: The New England journal of medicine 20050317
Title: COX-2 inhibitors--lessons in drug safety.
Journal: The New England journal of medicine 20050317
Title: COX-2 inhibitors--a lesson in unexpected problems.
Journal: The New England journal of medicine 20050317
Title: A liquid chromatography-mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasma.
Journal: Biomedical chromatography : BMC 20050301
Title: Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Meta-analysis: upper gastrointestinal tolerability of valdecoxib, a cyclooxygenase-2-specific inhibitor, compared with nonspecific nonsteroidal anti-inflammatory drugs among patients with osteoarthritis and rheumatoid arthritis.
Journal: Alimentary pharmacology & therapeutics 20050301
Title: COX-2 inhibitor induced anuric renal failure in a previously healthy young woman.
Journal: Clinical nephrology 20050301
Title: Lessons to learn from the COX-2 saga. Yes, FDA reforms are needed. And marketing distorts how medications are used. But one moral to the story is that all drugs have risks.
Journal: Harvard health letter 20050301
Title: Coxibs: can this class of drugs survive?
Journal: Vascular health and risk management 20050301
Title: Drug safety. FDA panel urges caution on many anti-inflammatory drugs.
Journal: Science (New York, N.Y.) 20050225
Title: Vioxx may go back on sale after scraping past FDA panel.
Journal: Nature 20050224
Title: Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.
Journal: Bioorganic & medicinal chemistry letters 20050215
Title: Prostaglandins mediate the cardioprotective effects of atorvastatin against ischemia-reperfusion injury.
Journal: Cardiovascular research 20050201
Title: The cyclooxygenase-2-specific inhibitor parecoxib sodium is as effective as 12 mg of morphine administered intramuscularly for treating pain after gynecologic laparotomy surgery.
Journal: Anesthesia and analgesia 20050201
Title: Central nervous system concentrations of cyclooxygenase-2 inhibitors in humans.
Journal: Anesthesiology 20050201
Title: Reduction of opioid-related adverse events using opioid-sparing analgesia with COX-2 inhibitors lacks documentation: a systematic review.
Journal: Acta anaesthesiologica Scandinavica 20050201
Title: Current concepts in nonoperative management of knee osteoarthritis.
Journal: Orthopedics 20050201
Title: Parecoxib, valdecoxib, and cardiovascular risk.
Journal: Circulation 20050125
Title: Arthritis medicines and cardiovascular events--'house of coxibs'.
Journal: JAMA 20050119
Title: Role of cyclooxygenase-2 in lipopolysaccharide-induced hyperalgesia in formalin test.
Journal: Indian journal of experimental biology 20050101
Title: Valdecoxib for treatment of primary dysmenorrhea. A randomized, double-blind comparison with placebo and naproxen.
Journal: Journal of general internal medicine 20050101
Title: Valdecoxib-induced systemic contact dermatitis confirmed by positive patch test.
Journal: Contact dermatitis 20050101
Title: Tolerance of nonsteroidal anti-inflammatory drug-sensitive patients to the highly specific cyclooxygenase 2 inhibitors rofecoxib and valdecoxib.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050101
Title: Enhancement of dissolution rate of valdecoxib using solid dispersions with polyethylene glycol 4000.
Journal: Drug development and industrial pharmacy 20050101
Title: Do selective cyclo-oxygenase-2 inhibitors have a future?
Journal: Drug safety 20050101
Title: Sentence ordered in drug counterfeiting case.
Journal: FDA consumer 20050101
Title: Cyclo-oxygenase-2 inhibitors: when should they be used in the elderly?
Journal: Drugs & aging 20050101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050101
Title: Valdecoxib for the management of chronic and acute pain.
Journal: Expert review of neurotherapeutics 20050101
Title: Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports.
Journal: Arthritis research & therapy 20050101
Title: SuperLigands - a database of ligand structures derived from the Protein Data Bank.
Journal: BMC bioinformatics 20050101
Title: Relative thromboembolic risks associated with COX-2 inhibitors.
Journal: The Annals of pharmacotherapy 20050101
Title: COX-2 selective inhibitors in the treatment of arthritis: a rheumatologist perspective.
Journal: Current topics in medicinal chemistry 20050101
Title: Impact of COX-2 inhibitors in common clinical practice a gastroenterologist's perspective.
Journal: Current topics in medicinal chemistry 20050101
Title: Regulatory paternalism in the market for drugs: lessons from Vioxx and Celebrex.
Journal: Yale journal of health policy, law, and ethics 20050101
Title: Treatment of osteoarthritis of the knee with a topical diclofenac solution: a randomised controlled, 6-week trial [ISRCTN53366886].
Journal: BMC musculoskeletal disorders 20050101
Title: FDA announces changes affecting the marketing of non-steroidal anti-inflammatory drugs.
Journal: FDA consumer 20050101
Title: Current state of therapy for pain and inflammation.
Journal: Arthritis research & therapy 20050101
Title: Cardiovascular and gastrointestinal effects of COX-2 inhibitors and NSAIDs: achieving a balance.
Journal: Arthritis research & therapy 20050101
Title: Practical approaches to minimizing gastrointestinal and cardiovascular safety concerns with COX-2 inhibitors and NSAIDs.
Journal: Arthritis research & therapy 20050101
Title: Balancing the gastrointestinal benefits and risks of nonselective NSAIDs.
Journal: Arthritis research & therapy 20050101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050101
Title: Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors.
Journal: Drug safety 20050101
Title: Cardiovascular complications of non-steroidal anti-inflammatory drugs.
Journal: Annals of clinical and laboratory science 20050101
Title: [Cyclooxygenase-2 inhibitors and the ethics of research].
Journal: Medicina 20050101
Title: The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain.
Journal: Pharmacological reports : PR 20050101
Title: COX-2 inhibitors and heart.
Journal: Indian heart journal 20050101
Title: Concern about one drug or entire class of drugs.
Journal: Reumatizam 20050101
Title: COX-2 selective inhibitors and heart health.
Journal: Postgraduate medicine 20050101
Title: Cardiovascular toxicity of valdecoxib.
Journal: The New England journal of medicine 20041223
Title: Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.
Journal: Bioorganic & medicinal chemistry letters 20041220
Title: ABT-963 [2-(3,4-difluoro-phenyl)-4-(3-hydroxy-3-methyl-butoxy)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin-3-one], a highly potent and selective disubstituted pyridazinone cyclooxgenase-2 inhibitor.
Journal: The Journal of pharmacology and experimental therapeutics 20041201
Title: Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.
Journal: Atherosclerosis 20041201
Title: Comparison of valdecoxib and an oxycodone-acetaminophen combination for acute musculoskeletal pain in the emergency department: a randomized controlled trial.
Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20041201
Title: Serious dermatologic reaction associated with valdecoxib: report of two cases.
Journal: Journal of the American Academy of Dermatology 20041201
Title: [The specific cox-2 inhibitor valdecoxib provides effective analgesia after inguinal hernia surgery].
Journal: Revista espanola de anestesiologia y reanimacion 20041201
Title: Could Bextra increase heart risks too?
Journal: Health news (Waltham, Mass.) 20041201
Title: A painkiller is pulled from the market. So what do you do now?
Journal: Heart advisor 20041201
Title: Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20041101
Title: Pfizer criticised over delay in admitting drug's problems.
Journal: BMJ (Clinical research ed.) 20041023
Title: Coxibs and cardiovascular disease.
Journal: The New England journal of medicine 20041021
Title: Presurgical intravenous parecoxib sodium and follow-up oral valdecoxib for pain management after laparoscopic cholecystectomy surgery reduces opioid requirements and opioid-related adverse effects.
Journal: Acta anaesthesiologica Scandinavica 20041001
Title: Efficacy and safety of valdecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials.
Journal: Pain 20041001
Title: The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II.
Journal: Inflammation 20041001
Title: Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal.
Journal: Journal of medicinal chemistry 20040923
Title: Stability study of amorphous valdecoxib.
Journal: International journal of pharmaceutics 20040910
Title: Reduced incidence of upper gastrointestinal ulcer complications with the COX-2 selective inhibitor, valdecoxib.
Journal: Alimentary pharmacology & therapeutics 20040901
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20040901
Title: First and second generations of COX-2 selective inhibitors.
Journal: Mini reviews in medicinal chemistry 20040801
Title: COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents.
Journal: Mini reviews in medicinal chemistry 20040801
Title: Effects of valdecoxib in the treatment of chronic low back pain: results of a randomized, placebo-controlled trial.
Journal: Clinical therapeutics 20040801
Title: Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
Journal: Bioorganic & medicinal chemistry letters 20040716
Title: Accuracy of splitting unscored valdecoxib tablets.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040715
Title: The analgesic effects that underlie patient satisfaction with treatment.
Journal: Pain 20040701
Title: Therapeutic interchange involving replacement of rofecoxib or celecoxib with valdecoxib.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040701
Title: Gastrointestinal side-effects of traditional non-steroidal anti-inflammatory drugs and new formulations.
Journal: Alimentary pharmacology & therapeutics 20040701
Title: Systematic review of the analgesic efficacy and tolerability of COX-2 inhibitors in post-operative pain control.
Journal: Journal of clinical pharmacy and therapeutics 20040601
Title: Preoperative parenteral parecoxib and follow-up oral valdecoxib reduce length of stay and improve quality of patient recovery after laparoscopic cholecystectomy surgery.
Journal: Anesthesia and analgesia 20040601
Title: Parecoxib: new preparation. A NSAID for postoperative pain: no proven advantage.
Journal: Prescrire international 20040601
Title: Prostaglandins: modulators of inflammation and cardiovascular risk.
Journal: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20040601
Title: A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain.
Journal: Acta anaesthesiologica Scandinavica 20040501
Title: Parecoxib sodium, an injectable COX-2-specific inhibitor, does not affect unfractionated heparin-regulated blood coagulation parameters.
Journal: Journal of clinical pharmacology 20040501
Title: Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501
Title: Valdecoxib versus rofecoxib in acute postsurgical pain: results of a randomized controlled trial.
Journal: Journal of pain and symptom management 20040501
Title: [Etoricoxib (Arcoxia)].
Journal: Revue medicale de Liege 20040501
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20040501
Title: Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles.
Journal: Journal of medicinal chemistry 20040422
Title: Quantitation of Valdecoxib in human plasma by high-performance liquid chromatography with ultraviolet absorbance detection using liquid-liquid extraction.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040405
Title: Cyclooxygenase-2 specific inhibitors in the treatment of dysmenorrhea.
Journal: Journal of pediatric and adolescent gynecology 20040401
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20040401
Title: [Valdecoxib (Bextra)].
Journal: Revue medicale de Liege 20040401
Title: Collision-induced dissociation of valdecoxib metabolites: a novel rearrangement involving an isoxazole ring.
Journal: Journal of mass spectrometry : JMS 20040301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20040301
Title: In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives.
Journal: Journal of medicinal chemistry 20040212
Title: Effective treatment of laparoscopic cholecystectomy pain with intravenous followed by oral COX-2 specific inhibitor.
Journal: Anesthesia and analgesia 20040201
Title: Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
Journal: Journal of medicinal chemistry 20040129
Title: Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.
Journal: Bioorganic & medicinal chemistry letters 20040119
Title: Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.
Journal: Pain 20040101
Title: Differential effects of selective COX-2 inhibitors on cell cycle regulation and proliferation of glioblastoma cell lines.
Journal: Cancer biology & therapy 20040101
Title: Clinical pharmacology of novel selective COX-2 inhibitors.
Journal: Current pharmaceutical design 20040101
Title: Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trials.
Journal: Clinical therapeutics 20040101
Title: S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495].
Journal: BMC musculoskeletal disorders 20040101
Title: Selective cyclooxygenase-2 inhibitors: similarities and differences.
Journal: Scandinavian journal of rheumatology 20040101
Title: A mechanistic perspective on the specificity and extent of COX-2 inhibition in pregnancy.
Journal: Drug safety 20040101
Title: Valdecoxib: a review of its use in the management of osteoarthritis, rheumatoid arthritis, dysmenorrhoea and acute pain.
Journal: Drugs 20040101
Title: Effects of the cyclooxygenase-2 specific inhibitor valdecoxib versus nonsteroidal antiinflammatory agents and placebo on cardiovascular thrombotic events in patients with arthritis.
Journal: American journal of therapeutics 20040101
Title: [Current EULAR data on valdecoxib. New study results of gastrointestinal safety and 'cost effectiveness'].
Journal: Krankenpflege Journal 20040101
Title: [Some new drugs: valdecoxib (Betra), voriconazole (Vfend), ezetimide (Ezetrol), teriparatide (Forsteo)].
Journal: Journal de pharmacie de Belgique 20040101
Title: Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1.
Journal: Molecular membrane biology 20040101
Title: The role of cyclooxygenase selective inhibitors in the gastrointestinal tract.
Journal: Current gastroenterology reports 20031201
Title: [Clinical pharmacology of the selective COX-2 inhibitors].
Journal: Der Orthopade 20031201
Title: Evaluation of the efficacy, safety and tolerability of valdecoxib gel (1%) in adult patients with painful inflammatory joint disease.
Journal: Journal of the Indian Medical Association 20031201
Title: Measuring dyspepsia-related health in randomized trials: the Severity of Dyspepsia Assessment (SODA) and its use in treatment with NSAIDs and COX-2-specific inhibitors.
Journal: Rheumatology (Oxford, England) 20031101
Title: The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors.
Journal: Rheumatology (Oxford, England) 20031101
Title: Economic evaluation of oral valdecoxib versus diclofenac in the treatment of patients with rheumatoid arthritis in a randomized clinical trial.
Journal: Rheumatology (Oxford, England) 20031101
Title: [Pain therapy in rheumatism. After 65 years of age coxibs are the best choice].
Journal: MMW Fortschritte der Medizin 20031016
Title: Valdecoxib is as effective as diclofenac in the management of rheumatoid arthritis with a lower incidence of gastroduodenal ulcers: results of a 26-week trial.
Journal: Rheumatology (Oxford, England) 20031001
Title: Expression of cyclooxygenase isozymes during morphogenesis and cycling of pelage hair follicles in mouse skin: precocious onset of the first catagen phase and alopecia upon cyclooxygenase-2 overexpression.
Journal: The Journal of investigative dermatology 20031001
Title: Development and validation of an automated SPE-LC-MS/MS assay for valdecoxib and its hydroxylated metabolite in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20030915
Title: Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
Journal: Journal of hypertension 20030901
Title: Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery.
Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20030901
Title: Valdecoxib, a COX-2-specific inhibitor, does not affect cardiac repolarization.
Journal: Journal of clinical pharmacology 20030901
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20030901
Title: [Tolerable pain therapy in rheumatism saves long-term costs. Despite this most COX-2 candidates receive conventional NSAID therapy].
Journal: MMW Fortschritte der Medizin 20030724
Title: Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20030701
Title: A comparison of the upper gastrointestinal mucosal effects of valdecoxib, naproxen and placebo in healthy elderly subjects.
Journal: Alimentary pharmacology & therapeutics 20030701
Title: Efficacy and safety of the first parenteral selective COX-2 inhibitor, parecoxib sodium, in adult patients with postoperative pain.
Journal: Journal of the Indian Medical Association 20030701
Title: [Progress in therapy of rheumatism. New coxib works especially fast].
Journal: MMW Fortschritte der Medizin 20030605
Title: Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery.
Journal: The Journal of thoracic and cardiovascular surgery 20030601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20030601
Title: The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial.
Journal: Journal of clinical pharmacology 20030501
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20030501
Title: [Adverse effect-free analgesia. New COX-2 inhibitor is even more selective].
Journal: MMW Fortschritte der Medizin 20030501
Title: Pharmacokinetics and metabolism of a COX-2 inhibitor, valdecoxib, in mice.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401
Title: Characterization of celecoxib and valdecoxib binding to cyclooxygenase.
Journal: Molecular pharmacology 20030401
Title: Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil.
Journal: Anesthesiology 20030401
Title: Valdecoxib-induced toxic epidermal necrolysis in a patient allergic to sulfa drugs.
Journal: Pharmacotherapy 20030401
Title: [Coxibs: highly selective cyclooxygenase-2 inhibitors. Part II. Side effects].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030401
Title: Gateways to clinical trials. March 2003.
Journal: Methods and findings in experimental and clinical pharmacology 20030301
Title: Valdecoxib: a review.
Journal: Clinical therapeutics 20030301
Title: Determination of valdecoxib and its metabolites in human urine by automated solid-phase extraction-liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030225
Title: Review article: The pharmacological properties and clinical use of valdecoxib, a new cyclo-oxygenase-2-selective inhibitor.
Journal: Alimentary pharmacology & therapeutics 20030215
Title: Clinical pharmacology of etoricoxib: a novel selective COX2 inhibitor.
Journal: Expert opinion on pharmacotherapy 20030201
Title: The COX-2 specific inhibitor, valdecoxib, is an effective, opioid-sparing analgesic in patients undergoing total knee arthroplasty.
Journal: Journal of pain and symptom management 20030201
Title: The second generation of COX-2 inhibitors: what advantages do the newest offer?
Journal: Drugs 20030101
Title: New warnings for Bextra.
Journal: FDA consumer 20030101
Title: Cyclooxygenase-2: from arthritis treatment to new indications for the prevention and treatment of cancer.
Journal: Clinical journal of oncology nursing 20030101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20030101
Title: [Pharmacology of cyclooxygenase 2 inhibition].
Journal: Wiener medizinische Wochenschrift (1946) 20030101
Title: COX-2: Where are we in 2003? - Be strong and resolute: continue to use COX-2 selective inhibitors at recommended dosages in appropriate patients.
Journal: Arthritis research & therapy 20030101
Title: COX-2: where are we in 2003?--distinction from NSAIDs becoming blurred.
Journal: Arthritis research & therapy 20030101
Title: Meloxicam and selective COX-2 inhibitors in the management of pain in the palliative care population.
Journal: The American journal of hospice & palliative care 20030101
Title: Clinical pharmacology of selective COX-2 inhibitors.
Journal: International journal of immunopathology and pharmacology 20030101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20021201
Title: The effects of cyclooxygenase isozyme inhibition on incisional wound healing in mouse skin.
Journal: The Journal of investigative dermatology 20021101
Title: COX-2 inhibitors and their role in gynecology.
Journal: Obstetrical & gynecological survey 20021101
Title: Evaluation of efficacy, safety and tolerability of valdecoxib in osteo-arthritis patients--an Indian study.
Journal: Journal of the Indian Medical Association 20021101
Title: Nonsteroidal antiinflammatory drugs and the stomach.
Journal: Current opinion in gastroenterology 20021101
Title: Incidence of gastroduodenal ulcers associated with valdecoxib compared with that of ibuprofen and diclofenac in patients with osteoarthritis.
Journal: European journal of gastroenterology & hepatology 20021001
Title: [Adverse effects of NSAID are insidious. No pain--despite life threatening gastric hemorrhage].
Journal: MMW Fortschritte der Medizin 20020912
Title: Disposition of a specific cyclooxygenase-2 inhibitor, valdecoxib, in human.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020901
Title: The influence of parecoxib, a parenteral cyclooxygenase-2 specific inhibitor, on the pharmacokinetics and clinical effects of midazolam.
Journal: Anesthesia and analgesia 20020901
Title: Efficacy and safety of valdecoxib in treating the signs and symptoms of rheumatoid arthritis: a randomized, controlled comparison with placebo and naproxen.
Journal: Rheumatology (Oxford, England) 20020901
Title: A single preoperative oral dose of valdecoxib, a new cyclooxygenase-2 specific inhibitor, relieves post-oral surgery or bunionectomy pain.
Journal: Anesthesiology 20020901
Title: Gateways to Clinical Trials.
Journal: Methods and findings in experimental and clinical pharmacology 20020901
Title: Valdecoxib, a cyclooxygenase-2-specific inhibitor, is effective in treating primary dysmenorrhea.
Journal: Obstetrics and gynecology 20020801
Title: Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery.
Journal: Anesthesiology 20020801
Title: Selecting new drugs for pain control: evidence-based decisions or clinical impressions?
Journal: Journal of the American Dental Association (1939) 20020801
Title: Valdecoxib does not impair platelet function.
Journal: The American journal of emergency medicine 20020701
Title: Role of COX-2 inhibitors in the evolution of acute pain management.
Journal: Journal of pain and symptom management 20020701
Title: Randomized placebo-controlled trial comparing efficacy and safety of valdecoxib with naproxen in patients with osteoarthritis.
Journal: The Journal of family practice 20020601
Title: Right ballpark, wrong base: assessing safety of NSAIDs.
Journal: The Journal of family practice 20020601
Title: The analgesic efficacy of valdecoxib vs. oxycodone/acetaminophen after oral surgery.
Journal: Journal of the American Dental Association (1939) 20020501
Title: Valdecoxib (Bextra)--a new cox-2 inhibitor.
Journal: The Medical letter on drugs and therapeutics 20020429
Title: Efficacy and safety of the COX-2 specific inhibitor valdecoxib in the management of osteoarthritis of the hip: a randomized, double-blind, placebo-controlled comparison with naproxen.
Journal: Osteoarthritis and cartilage 20020401
Title: Cox-2 inhibitors: today and tomorrow.
Journal: The American journal of the medical sciences 20020401
Title: Nonsteroidal anti-inflammatory drugs, coxibs, and cardio-renal physiology: a mechanism-based approach.
Journal: The American journal of cardiology 20020321
Title: Valdecoxib (Pharmacia).
Journal: Current opinion in investigational drugs (London, England : 2000) 20020201
Title: Effects of parecoxib, a parenteral COX-2-specific inhibitor, on the pharmacokinetics and pharmacodynamics of propofol.
Journal: Anesthesiology 20020101
Title: Valdecoxib, a COX-2-specific inhibitor, is an efficacious, opioid-sparing analgesic in patients undergoing hip arthroplasty.
Journal: American journal of therapeutics 20020101
Title: Valdecoxib is more efficacious than rofecoxib in relieving pain associated with oral surgery.
Journal: American journal of therapeutics 20020101
Title: New COX-2 arthritis drug receives FDA approval.
Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20020101
Title: COX-2-selective inhibitors in the treatment of arthritis.
Journal: Cleveland Clinic journal of medicine 20020101
Title: Development and clinical application of COX-2-selective inhibitors for the treatment of osteoarthritis and rheumatoid arthritis.
Journal: Cleveland Clinic journal of medicine 20020101
Title: Valdecoxib.
Journal: Reviews in gastroenterological disorders 20020101
Title: Valdecoxib.
Journal: Drugs 20020101
Title: Etoricoxib.
Journal: Drugs 20020101
Title: The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity.
Journal: Current medical research and opinion 20020101
Title: Mechanism of inhibition of novel COX-2 inhibitors.
Journal: Advances in experimental medicine and biology 20020101
Title: A pharmacokinetic study of intramuscular (i.m.) parecoxib sodium in normal subjects.
Journal: Journal of clinical pharmacology 20011001
Title: Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis.
Journal: Journal of medicinal chemistry 20010927
Title: The injectable cyclooxygenase-2-specific inhibitor parecoxib sodium has analgesic efficacy when administered preoperatively.
Journal: Anesthesia and analgesia 20010901
Title: Upper gastrointestinal safety evaluation of parecoxib sodium, a new parenteral cyclooxygenase-2-specific inhibitor, compared with ketorolac, naproxen, and placebo.
Journal: Clinical therapeutics 20010901
Title: A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors.
Journal: The Biochemical journal 20010801
Title: Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.
Journal: The Journal of pharmacology and experimental therapeutics 20010201
Title: Parecoxib (parecoxib sodium).
Journal: Drugs 20010101
Title: 4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, valdecoxib: a potent and selective inhibitor of COX-2.
Journal: Journal of medicinal chemistry 20000309
Title: Talley JJ, et al. 4--Methyl-3-phenylisoxazol-4-yl- benzenesulfonamide, valdecoxib: a potent and selective inhibitor of COX-2. J Med Chem. 2000 Mar 9;43(5):775-7.
Title: Wiktorowska-Owczarek A. The effect of valdecoxib on the production of growth factors evoked by hypoxia and bacterial lipopolysaccharide in HMEC-1 cells. Adv Clin Exp Med. 2013 Nov-Dec;22(6):795-800.
Title: Kumar A, et al. Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress. Neurosci Bull. 2010 Feb;26(1):17-27.
