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18296-44-1,MFCD00868024
Catalog No.:AA002487

18296-44-1 | Valepotriate

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1mg
≥98%
in stock  
$42.00   $29.00
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5mg
≥98%
in stock  
$195.00   $136.00
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10mg
≥98%
in stock  
$348.00   $243.00
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25mg
≥98%
in stock  
$665.00   $465.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002487
Chemical Name:
Valepotriate
CAS Number:
18296-44-1
Molecular Formula:
C22H30O8
Molecular Weight:
422.4688
MDL Number:
MFCD00868024
SMILES:
CC(=O)OCC1=CO[C@H]([C@H]2C1=C[C@@H]([C@]12OC1)OC(=O)CC(C)C)OC(=O)CC(C)C
Properties
Computed Properties
 
Complexity:
765  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
8  
Rotatable Bond Count:
11  
XLogP3:
1.8  

Literature

Title: Effect of storage time and conditions on the diene valepotriates content of the extract of Valeriana glechomifolia obtained by supercritical carbon dioxide.

Journal: Phytochemical analysis : PCA 20120101

Title: In vitro effect of valepotriates isolated from Valeriana glechomifolia on rat P-type ATPases.

Journal: Planta medica 20111001

Title: Concise synthesis of 5,6-dihydrovaltrate leading to enhanced Rev-export inhibitory congener.

Journal: Bioorganic & medicinal chemistry 20100815

Title: Bioisostere of valtrate, anti-HIV principle by inhibition for nuclear export of Rev.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Acylated iridoids with cytotoxicity from Valeriana jatamansi.

Journal: Journal of natural products 20090401

Title: Sorbifolivaltrates A-D, diene valepotriates from Valeriana sorbifolia(1).

Journal: Journal of natural products 20071201

Title: [Study on quality specification of Rhizoma et Radix Valeriana Jatamansi].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101

Title: Control of development and valepotriate production by auxins in micropropagated Valeriana glechomifolia.

Journal: Plant cell reports 20041001

Title: New Rev-transport inhibitor with anti-HIV activity from Valerianae Radix.

Journal: Bioorganic & medicinal chemistry letters 20021021

Title: Quantitative determination of valepotriates from Valeriana native to South Brazil.

Journal: Planta medica 20020601

Title: Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20020501

Title: Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp.procera.

Journal: Journal of natural products 20020401

Title: Yan YY, et al. A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa-dependent apoptosis in human pancreatic cancer cells. Acta Pharmacol Sin. 2020 Feb 11.

Title: Wu A, et al. Anti-epileptic Effects of Valepotriate Isolated from Valeriana jatamansi Jones and Its Possible Mechanisms. Pharmacogn Mag. 2017 Jul-Sep;13(51):512-516.

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