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1849603-72-0,MFCD08141843
Catalog No.:AA01V3M9

1849603-72-0 | SBI-553

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Purity
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1mg
≥98%
in stock  
$42.00   $29.00
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5mg
≥98%
in stock  
$183.00   $128.00
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10mg
≥98%
in stock  
$322.00   $225.00
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25mg
≥98%
in stock  
$703.00   $492.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01V3M9
Chemical Name:
SBI-553
CAS Number:
1849603-72-0
Molecular Formula:
C26H31FN4O2
Molecular Weight:
450.5483
MDL Number:
MFCD08141843
SMILES:
OCCN(c1ccc2c(c1)c(nc(n2)C1(F)CC1)N1CCC(CC1)c1ccccc1OC)C
Properties

Downstream Synthesis Route
1849603-72-0   
CASUnavailable 
  1849605-68-0 

[1]CurrentPatentAssignee:SANFORDBURNHAMPREBYSMEDICALDISCOVERYINSTITUTE-WO2015/200534,2015,A2Locationinpatent:Paragraph00697

[1]Pinkerton,AnthonyB.;Peddibhotla,Satyamaheshwar;Yamamoto,Fusayo;Slosky,LaurenM.;Bai,Yushi;Maloney,Patrick;Hershberger,Paul;Hedrick,MichaelP.;Falter,Bekhi;Ardecky,RobertJ.;Smith,LaytonH.;Chung,ThomasD.Y.;Jackson,MichaelR.;Caron,MarcG.;Barak,LawrenceS.[JournalofMedicinalChemistry,2019,vol.62,#17,p.8357-8363]

[1]Pinkerton,AnthonyB.;Peddibhotla,Satyamaheshwar;Yamamoto,Fusayo;Slosky,LaurenM.;Bai,Yushi;Maloney,Patrick;Hershberger,Paul;Hedrick,MichaelP.;Falter,Bekhi;Ardecky,RobertJ.;Smith,LaytonH.;Chung,ThomasD.Y.;Jackson,MichaelR.;Caron,MarcG.;Barak,LawrenceS.[JournalofMedicinalChemistry,2019,vol.62,#17,p.8357-8363]

[1]Pinkerton,AnthonyB.;Peddibhotla,Satyamaheshwar;Yamamoto,Fusayo;Slosky,LaurenM.;Bai,Yushi;Maloney,Patrick;Hershberger,Paul;Hedrick,MichaelP.;Falter,Bekhi;Ardecky,RobertJ.;Smith,LaytonH.;Chung,ThomasD.Y.;Jackson,MichaelR.;Caron,MarcG.;Barak,LawrenceS.[JournalofMedicinalChemistry,2019,vol.62,#17,p.8357-8363]

Literature

Title: Pinkerton AB, et al. Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. J Med Chem. 2019 Aug 20.

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