Title: The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells.
Journal: PloS one 20160101
Title: Cyclooxygenase-1 serves a vital hepato-protective function in chemically induced acute liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201
Title: Anti-inflammatory effects of 7-hydroxyl-1-methylindole-3-acetonitrile, a synthetic arvelexin derivative, on the macrophages through destabilizing mPGES-1 mRNA and suppressing NF-κB activation.
Journal: Chemico-biological interactions 20141205
Title: Immunohistochemical and functional studies for M₃ muscarinic receptors and cyclo-oxygenase-2 expressed in the mouse atrium.
Journal: Autonomic & autacoid pharmacology 20121001
Title: Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition.
Journal: American journal of physiology. Renal physiology 20120715
Title: Nonsteroidal anti-inflammatory drug-activated gene-1 plays a role in the impairing effects of cyclooxygenase inhibitors on gastric ulcer healing.
Journal: The Journal of pharmacology and experimental therapeutics 20120701
Title: Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
Journal: Bioorganic & medicinal chemistry 20120501
Title: Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).
Journal: Journal of medicinal chemistry 20120426
Title: Retinoic acid increases hypoxia-inducible factor-1α through intracrine prostaglandin E(2) signaling in human renal proximal tubular cells HK-2.
Journal: Biochimica et biophysica acta 20120401
Title: Interaction between selective cyclooxygenase inhibitors and capsaicin-sensitive afferent sensory nerves in pathogenesis of stress-induced gastric lesions. Role of oxidative stress.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120401
Title: Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120321
Title: Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.
Journal: Journal of medicinal chemistry 20120308
Title: Relative contribution of cyclooxygenases, epoxyeicosatrienoic acids, and pH to the cerebral blood flow response to vibrissal stimulation.
Journal: American journal of physiology. Heart and circulatory physiology 20120301
Title: Hemokinin-1 stimulates prostaglandin E₂ production in human colon through activation of cyclooxygenase-2 and inhibition of 15-hydroxyprostaglandin dehydrogenase.
Journal: The Journal of pharmacology and experimental therapeutics 20120101
Title: Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells.
Journal: Pharmacological research 20120101
Title: Effects of cyclooxygenase inhibitors in combination with taxol on expression of cyclin D1 and Ki-67 in a xenograft model of ovarian carcinoma.
Journal: International journal of molecular sciences 20120101
Title: Cyclooxygenase-2-derived prostacyclin protective role on endotoxin-induced mouse cardiomyocyte mortality.
Journal: Cardiovascular toxicology 20111201
Title: SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111201
Title: Nitric oxide-releasing aspirin but not conventional aspirin improves healing of experimental colitis.
Journal: World journal of gastroenterology 20110928
Title: Balloon catheter injury abolishes phenylephrine-induced relaxation in the rat contralateral carotid.
Journal: British journal of pharmacology 20110601
Title: Human prostaglandin H synthase (hPHS)-1 and hPHS-2 in amphetamine analog bioactivation, DNA oxidation, and cytotoxicity.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110301
Title: Progestogens reduce thromboxane production by cultured human endothelial cells.
Journal: Climacteric : the journal of the International Menopause Society 20110201
Title: Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201
Title: Cyclooxygenase-2 protects germ cells against spermatogenesis disturbance in experimental cryptorchidism model mice.
Journal: Journal of andrology 20110101
Title: Inhibition of cyclooxygenase-2 prevents adverse effects induced by phosphodiesterase type 4 inhibitors in rats.
Journal: British journal of pharmacology 20110101
Title: Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
Journal: European journal of medicinal chemistry 20110101
Title: Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian carcinoma in vivo.
Journal: International journal of molecular sciences 20110101
Title: [Regulatory interconnections of cyclooxigenase and inducible no-synthase in urinary bladder epithelial cells of the frog Rana temporaria under action of bacterial stimuli].
Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20110101
Title: Blockade of leukocyte haptokinesis and haptotaxis by ketoprofen, diclofenac and SC-560.
Journal: BMC immunology 20110101
Title: Non-steroidal anti-inflammatory drugs inhibit calpain activity and membrane localization of calpain 2 protease.
Journal: The international journal of biochemistry & cell biology 20101201
Title: Augmented cyclooxygenase-2 effects on renal function during varying states of angiotensin II.
Journal: American journal of physiology. Renal physiology 20101101
Title: Chronic treatment with the cannabinoid 1 antagonist rimonabant altered vasoactive cyclo-oxygenase-derived products on arteries from obese Zucker rats.
Journal: Journal of cardiovascular pharmacology 20101101
Title: Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells.
Journal: European journal of medicinal chemistry 20101101
Title: NS-398 (a selective cyclooxygenase-2 inhibitor) decreases agonist-induced contraction of the human ureter via calcium channel inhibition.
Journal: Journal of endourology 20101101
Title: Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents.
Journal: Scandinavian journal of gastroenterology 20100801
Title: Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2.
Journal: The Journal of pharmacology and experimental therapeutics 20100801
Title: Ghrelin signaling in human mesenteric arteries.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100801
Title: Triterpene saponins from Clematis chinensis and their potential anti-inflammatory activity.
Journal: Journal of natural products 20100723
Title: Gastric acid is the key modulator in the pathogenesis of non-steroidal anti-inflammatory drug-induced ulceration in rats.
Journal: Clinical and experimental pharmacology & physiology 20100701
Title: Paradoxical thrombotic effects of aspirin: experimental study on 1000 animals.
Journal: Cardiovascular & hematological disorders drug targets 20100601
Title: Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells.
Journal: Lung cancer (Amsterdam, Netherlands) 20100501
Title: Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.
Journal: Clinica chimica acta; international journal of clinical chemistry 20100402
Title: Thromboxane A(2) promotes soluble CD40 ligand release from human platelets.
Journal: Atherosclerosis 20100401
Title: Effects of a selective cyclooxygenase-1 inhibitor in SKOV-3 ovarian carcinoma xenograft-bearing mice.
Journal: Medical oncology (Northwood, London, England) 20100301
Title: The effects of nepafenac and amfenac on retinal angiogenesis.
Journal: Brain research bulletin 20100215
Title: Cyclooxygenase-1 mediates the immediate corticosterone response to peripheral immune challenge induced by lipopolysaccharide.
Journal: Neuroscience letters 20100205
Title: Effects of cyclooxygenase inhibitor treatment on the renal toxicity of cisplatin in rats.
Journal: Cancer chemotherapy and pharmacology 20100201
Title: Improvement in neurogenic detrusor overactivity by peripheral C fiber's suppression with cyclooxygenase inhibitors.
Journal: The Journal of urology 20100201
Title: Synthesis and biological evaluation of nitrogen-containing chalcones as possible anti-inflammatory and antioxidant agents.
Journal: Bioorganic & medicinal chemistry letters 20100115
Title: Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids.
Journal: Pain 20100101
Title: The influence of constitutive COX-2 in smooth muscle tissue on the contractile effect of phenylephrine in the rat abdominal aorta.
Journal: Frontiers in bioscience (Elite edition) 20100101
Title: Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice.
Journal: PloS one 20100101
Title: Roles of NADPH oxidase in occurrence of gastric damage and expression of cyclooxygenase-2 during ischemia/reperfusion in rat stomachs.
Journal: Journal of pharmacological sciences 20091201
Title: Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091014
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Anti-bovine viral diarrhoea virus and hepatitis C virus activity of the cyclooxygenase inhibitor SC-560.
Journal: Antiviral chemistry & chemotherapy 20090925
Title: Increased cyclooxygenase activity impairs apoptosis of inflammatory neutrophils in mice lacking gelatinase B/matrix metalloproteinase-9.
Journal: Immunology 20090901
Title: Cyclooxygenase-1 or -2--which one mediates lipopolysaccharide-induced hypothermia?
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090801
Title: Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment.
Journal: PLoS biology 20090801
Title: Protective effects of amifostine and cyclooxygenase-1 inhibitor against normal human epidermal keratinocyte toxicity induced by methotrexate and 5-fluorouracil.
Journal: Basic & clinical pharmacology & toxicology 20090701
Title: Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells.
Journal: Biochemical and biophysical research communications 20090424
Title: Cyclooxygenase 2 inhibition suppresses tubuloglomerular feedback: roles of thromboxane receptors and nitric oxide.
Journal: American journal of physiology. Renal physiology 20090401
Title: Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.
Journal: Journal of medicinal chemistry 20090226
Title: Effects of nonselective and selective cyclooxygenase inhibitors on small intestinal motility in the horse.
Journal: Research in veterinary science 20090201
Title: COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090201
Title: Cyclo-oxygenase-1-selective inhibitor SC-560.
Journal: Acta crystallographica. Section E, Structure reports online 20090201
Title: Effects of a cyclooxygenase-1-selective inhibitor in a mouse model of ovarian cancer, administered alone or in combination with ibuprofen, a nonselective cyclooxygenase inhibitor.
Journal: Medical oncology (Northwood, London, England) 20090101
Title: Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat.
Journal: Neonatology 20090101
Title: Resveratrol inhibits prostaglandin formation in IL-1beta-stimulated SK-N-SH neuronal cells.
Journal: Journal of neuroinflammation 20090101
Title: Differential involvement of cyclooxygenase isoforms in neutrophil migration in vivo and in vitro.
Journal: European journal of pharmacology 20081119
Title: Role of cyclooxygenase isoforms in prostacyclin biosynthesis and murine prehepatic portal hypertension.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20081101
Title: Cyclooxygenase-dependent vasoconstricting factor(s) in remodelled rat femoral arteries.
Journal: Cardiovascular research 20080701
Title: Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells.
Journal: Oncology reports 20080701
Title: Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
Journal: Journal of medicinal chemistry 20080626
Title: Cyclooxygenase-2 derived PGE2 and PGI2 play an important role via EP2 and PPARdelta receptors in early steps of oil induced decidualization in mice.
Journal: Placenta 20080601
Title: Expression of cyclooxygenase genes and production of prostaglandins during ovulation in the ovarian follicles of Xenopus laevis.
Journal: General and comparative endocrinology 20080601
Title: Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501
Title: Drug-induced alterations to gene and protein expression in intestinal epithelial cell 6 cells suggest a role for calpains in the gastrointestinal toxicity of nonsteroidal anti-inflammatory agents.
Journal: The Journal of pharmacology and experimental therapeutics 20080501
Title: Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080501
Title: The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity.
Journal: Anesthesia and analgesia 20080301
Title: Cyclooxygenase-1 suppresses lipopolysaccharide-induced changes in rat gastric inducible nitric oxide synthase.
Journal: Critical care medicine 20080201
Title: Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells.
Journal: Cell biochemistry and function 20080101
Title: Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.
Journal: American journal of physiology. Heart and circulatory physiology 20080101
Title: Effects of aspirin, nimesulide, and SC-560 on vasopressin-induced contraction of human gastroepiploic artery and saphenous vein.
Journal: Critical care medicine 20080101
Title: Cyclooxygenase-2-derived endogenous prostacyclin reduces apoptosis and enhances embryo viability in mouse.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101
Title: Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20071201
Title: Roles of platelet and endothelial cell COX-1 in hypercholesterolemia-induced microvascular dysfunction.
Journal: American journal of physiology. Heart and circulatory physiology 20071201
Title: Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Journal: British journal of pharmacology 20071101
Title: Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
Journal: World journal of gastroenterology 20071014
Title: Aggravation by selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesions in rats.
Journal: Digestive diseases and sciences 20070901
Title: Involvement of prostaglandin E receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901
Title: Abnormalities of prostaglandins and cyclooxygenase enzymes in female patients with slow-transit constipation.
Journal: Gastroenterology 20070801
Title: Bradykinin-induced nociceptor sensitisation to heat depends on cox-1 and cox-2 in isolated rat skin.
Journal: Pain 20070701
Title: Dexamethasone damages the rat stomach but not small intestine during inhibition of COX-1.
Journal: Digestive diseases and sciences 20070601
Title: Cyclooxygenase-1 inhibition delays recovery of the cutaneous barrier disruption caused by mechanical scratching in mice.
Journal: The British journal of dermatology 20070601
Title: Interactive actions of prostaglandin and epidermal growth factor to enhance proliferation of granulosa cells from chicken prehierarchical follicles.
Journal: Prostaglandins & other lipid mediators 20070601
Title: Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer.
Journal: Cancer research 20070601
Title: Cyclooxygenase (COX)-1 and COX-2 participate in 5,6-epoxyeicosatrienoic acid-induced contraction of rabbit intralobar pulmonary arteries.
Journal: The Journal of pharmacology and experimental therapeutics 20070501
Title: Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells.
Journal: Biochemical pharmacology 20070501
Title: Escherichia coli lipopolysaccharides produce serotype-specific hypothermic response in biotelemetered rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070501
Title: Aspirin and COX-2 inhibitor nimesulide potentiate adrenergic contractions of human gastroepiploic artery.
Journal: American journal of hypertension 20070501
Title: Thromboxane receptor blockade improves the antiatherogenic effect of thromboxane A2 suppression in LDLR KO mice.
Journal: Blood 20070415
Title: Spinal prostaglandins facilitate exaggerated A- and C-fiber-mediated reflex responses and are critical to the development of allodynia early after L5-L6 spinal nerve ligation.
Journal: Anesthesiology 20070401
Title: Evaluation of cyclooxygenase 2 derived endogenous prostacyclin in mouse preimplantation embryo development in vitro.
Journal: Life sciences 20070327
Title: Screening method for nonsteroidal antiinflammatory drugs based on the cyclooxygenase 2 pathway activated by serum-free stimulation in A549 cells.
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070301
Title: [Effects of cyclooxygenase-1 inhibitor on spinal ERK expression in rats with postoperative pain].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201
Title: Intrathecally administered COX-2 but not COX-1 or COX-3 inhibitors attenuate streptozotocin-induced mechanical hyperalgesia in rats.
Journal: European journal of pharmacology 20070105
Title: Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular risk.
Journal: Arthritis research & therapy 20070101
Title: Acetaminophen, phenacetin and dipyrone do not modulate pressor responses to arachidonic Acid or to pressor agents.
Journal: Pharmacology 20070101
Title: Effect of cyclooxygenase on 'window of implantation' in mouse.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20070101
Title: Reverse effect of aspirin: is the prothrombotic effect after aspirin discontinuation mediated by cyclooxygenase 2 inhibition?
Journal: Pathophysiology of haemostasis and thrombosis 20070101
Title: Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Journal: European journal of pharmacology 20061215
Title: Intestinal effects of nonselective and selective cyclooxygenase inhibitors in the rat.
Journal: European journal of pharmacology 20061215
Title: Endogenous prostaglandins regulate spontaneous contractile activity of uterine strips isolated from non-pregnant pigs.
Journal: Prostaglandins & other lipid mediators 20061201
Title: Effects of selective PGE2 receptor antagonists in esophageal adenocarcinoma cells derived from Barrett's esophagus.
Journal: Prostaglandins & other lipid mediators 20061201
Title: Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1.
Journal: Experimental physiology 20061101
Title: Cis-unsaturated fatty acids stimulate reactive oxygen species generation and lipid peroxidation in human spermatozoa.
Journal: The Journal of clinical endocrinology and metabolism 20061001
Title: Prostacyclin production in tryptase and thrombin stimulated human bladder endothelial cells: effect of pretreatment with phospholipase A2 and cyclooxygenase inhibitors.
Journal: The Journal of urology 20061001
Title: Effects of selective inhibition of cyclooxygenase and lipooxygenase pathways in follicle rupture and ovulation in the rat.
Journal: Reproduction (Cambridge, England) 20061001
Title: Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061001
Title: Differential expression of cyclooxygenase 1 and cyclooxygenase 2 in the bovine oviduct.
Journal: The Journal of endocrinology 20061001
Title: Kinase-dependent, retinoic acid receptor-independent up-regulation of cyclooxygenase-2 by all-trans retinoic acid in human mesangial cells.
Journal: British journal of pharmacology 20060901
Title: Intrathecal administration of a cylcooxygenase-1, but not a cyclooxygenase-2 inhibitor, reverses the effects of laparotomy on exploratory activity in rats.
Journal: Anesthesia and analgesia 20060901
Title: Roles of endogenous prostaglandins and cyclooxygenase isozymes in healing of indomethacin-induced small intestinal lesions in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Endogenous opioids mediate the hypoalgesia induced by selective inhibitors of cyclo-oxygenase 2 in rat paws treated with carrageenan.
Journal: Neuropharmacology 20060701
Title: Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701
Title: Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Journal: Digestive diseases and sciences 20060701
Title: Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells.
Journal: Experimental & molecular medicine 20060630
Title: Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20060601
Title: Lipopolysaccharide induces epithelium- and prostaglandin E(2)-dependent relaxation of mouse isolated trachea through activation of cyclooxygenase (COX)-1 and COX-2.
Journal: The Journal of pharmacology and experimental therapeutics 20060501
Title: Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20060501
Title: Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060501
Title: 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole acts in a reactive oxygen species-dependent manner to suppress human lung cancer growth.
Journal: Journal of cancer research and clinical oncology 20060401
Title: Products of cyclooxygenase-2 depress duodenal function in rats subjected to abdominal surgery.
Journal: Acta physiologica (Oxford, England) 20060401
Title: Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Roles of cyclooxygenase-2 and prostacyclin/IP receptors in mucosal defense against ischemia/reperfusion injury in mouse stomach.
Journal: The Journal of pharmacology and experimental therapeutics 20060201
Title: The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Journal: International journal of molecular medicine 20060201
Title: Effects of cyclooxygenase-1 and -2 inhibition on gastric acid secretion and cardiovascular functions in rats.
Journal: Pharmacology 20060101
Title: Dexamethasone impairs the gastric mucosal integrity in rats treated with a cyclooxygenase-1 but not with a cyclooxygenase-2 inhibitor.
Journal: Pharmacology 20060101
Title: Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells.
Journal: Neurochemistry international 20051201
Title: Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli.
Journal: Journal of neurochemistry 20051201
Title: Cyclo-oxygenase-2 contributes to constitutive prostanoid production in rat kidney and brain.
Journal: The Biochemical journal 20051101
Title: Synthesis and antiinflammatory activity of coumarin derivatives.
Journal: Journal of medicinal chemistry 20051006
Title: Radiosynthesis and in vivo evaluation of 11C-labeled 1,5-diarylpyrazole derivatives for mapping cyclooxygenases.
Journal: Annals of nuclear medicine 20051001
Title: Central cyclooxygenase inhibitors reduced IL-1beta-induced hyperalgesia in temporomandibular joint of freely moving rats.
Journal: Pain 20050901
Title: COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.
Journal: Scandinavian journal of gastroenterology 20050801
Title: Rofecoxib produces intestinal but not gastric damage in the presence of a low dose of indomethacin in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20050701
Title: Selective cyclooxygenase (COX) inhibition causes damage to portal hypertensive gastric mucosa: roles of nitric oxide and NF-kappaB.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Title: Progestogens stimulate prostacyclin production by human endothelial cells.
Journal: Human reproduction (Oxford, England) 20050601
Title: Selective inhibitors differentially affect cyclooxygenase-dependent pial arteriolar responses in newborn pigs.
Journal: Pediatric research 20050601
Title: Cyclo-oxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus.
Journal: Journal of neurochemistry 20050601
Title: Cyclooxygenase-1 mediates the final stage of morphine-induced delayed cardioprotection in concert with cyclooxygenase-2.
Journal: Journal of the American College of Cardiology 20050517
Title: Cyclooxygenase-2 is an obligatory factor in methamphetamine-induced neurotoxicity.
Journal: The Journal of pharmacology and experimental therapeutics 20050501
Title: Preoperative inhibition of cyclooxygenase-1 in the spinal cord reduces postoperative pain.
Journal: Anesthesia and analgesia 20050501
Title: Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer.
Journal: Cancer research 20050501
Title: The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).
Journal: Molecular cancer therapeutics 20050501
Title: Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer.
Journal: The Journal of steroid biochemistry and molecular biology 20050501
Title: Preemptive analgesia by zaltoprofen that inhibits bradykinin action and cyclooxygenase in a post-operative pain model.
Journal: Neuroscience research 20050401
Title: Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats.
Journal: American journal of veterinary research 20050401
Title: Cyclooxygenase-2 inhibition improves vascular endothelial dysfunction in a rat model of endotoxic shock: role of inducible nitric-oxide synthase and oxidative stress.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Induced microsomal PGE synthase-1 is involved in cyclooxygenase-2-dependent PGE2 production in gastric fibroblasts.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050201
Title: Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein.
Journal: Molecular pharmacology 20050201
Title: In vivo endothelial interaction between ACE and COX inhibitors.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050201
Title: The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
Journal: Experimental cell research 20050115
Title: Functional mechanism underlying cyclooxygenase-2 expression in rat small intestine following administration of indomethacin: relation to intestinal hypermotility.
Journal: Journal of gastroenterology and hepatology 20050101
Title: Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib.
Journal: Inflammopharmacology 20050101
Title: Selective nonsteroidal anti-inflammatory drugs induce thymosin beta-4 and alter actin cytoskeletal organization in human colorectal cancer cells.
Journal: The Journal of pharmacology and experimental therapeutics 20041201
Title: Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
Journal: Journal of the National Cancer Institute 20041201
Title: Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules.
Journal: American journal of physiology. Renal physiology 20041101
Title: Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion.
Journal: Muscle & nerve 20041001
Title: Dose-dependent immunomodulatory effects of acetylsalicylic acid and indomethacin in human whole blood: potential role of cyclooxygenase-2 inhibition.
Journal: Scandinavian journal of immunology 20041001
Title: Ischemic preconditioning of remote organs attenuates gastric ischemia-reperfusion injury through involvement of prostaglandins and sensory nerves.
Journal: European journal of pharmacology 20040919
Title: Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons.
Journal: European journal of pharmacology 20040913
Title: Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas.
Journal: European journal of pharmacology 20040913
Title: Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone.
Journal: Circulation 20040907
Title: High-performance liquid chromatographic analysis of a selective cyclooxygenase-1 inhibitor SC-560 in rat serum: application to pharmacokinetic studies.
Journal: Journal of pharmaceutical and biomedical analysis 20040903
Title: Antitussive effect of NS-398, a selective cyclooxygenase-2 inhibitor, in guinea pigs.
Journal: European journal of pharmacology 20040823
Title: Induction of small intestinal damage in rats following combined treatment with cyclooxygenase-2 and nitric-oxide synthase inhibitors.
Journal: The Journal of pharmacology and experimental therapeutics 20040801
Title: Prostaglandin E2 is a product of induced prostaglandin-endoperoxide synthase 2 and microsomal-type prostaglandin E synthase at the implantation site of the hamster.
Journal: The Journal of biological chemistry 20040716
Title: Enhanced contractility of renal afferent arterioles from angiotensin-infused rabbits: roles of oxidative stress, thromboxane prostanoid receptors, and endothelium.
Journal: Circulation research 20040611
Title: Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells.
Journal: Journal of lipid research 20040601
Title: TNF-alpha hyperpolarizes membrane potential and potentiates the response to nicotinic receptor stimulation in cultured rat myenteric neurones.
Journal: Acta physiologica Scandinavica 20040501
Title: Cyclooxygenase 1-dependent production of F2-isoprostane and changes in redox status during warm renal ischemia-reperfusion.
Journal: Free radical biology & medicine 20040415
Title: Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells.
Journal: Cellular immunology 20040401
Title: Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells.
Journal: Carcinogenesis 20040301
Title: Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301
Title: Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility.
Journal: Digestive diseases and sciences 20040201
Title: Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
Journal: Journal of medicinal chemistry 20040129
Title: Genetic deficiency or pharmacological inhibition of cyclooxygenase-1 or -2 induces mouse keratinocyte differentiation in vitro and in vivo.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101
Title: Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures.
Journal: Journal of neurochemistry 20040101
Title: Raloxifene increases the capacity of serum to promote prostacyclin release in human endothelial cells: implication of COX-1 and COX-2.
Journal: Menopause (New York, N.Y.) 20040101
Title: Role of COX-1 and -2 in prostanoid generation and modulation of angiotensin II responses.
Journal: American journal of physiology. Heart and circulatory physiology 20031201
Title: Inhibition of spinal prostaglandin synthesis early after L5/L6 nerve ligation prevents the development of prostaglandin-dependent and prostaglandin-independent allodynia in the rat.
Journal: Anesthesiology 20031101
Title: Specific roles of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide-induced fever and Fos expression in rat brain.
Journal: The Journal of comparative neurology 20030811
Title: Mechanisms of angiotensin-converting enzyme inhibitor induced thrombolysis in Wistar rats.
Journal: Thrombosis research 20030615
Title: Mechanotransduction in bone cells proceeds via activation of COX-2, but not COX-1.
Journal: Biochemical and biophysical research communications 20030606
Title: Cyclooxygenase-1-coupled prostaglandin biosynthesis constitutes an essential prerequisite for skin repair.
Journal: The Journal of investigative dermatology 20030501
Title: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells.
Journal: Circulation research 20030418
Title: Induction of cyclooxygenase-1 and -2 modulates angiogenic responses to engagement of alphavbeta3.
Journal: British journal of haematology 20030401
Title: Spinal nerve injury activates prostaglandin synthesis in the spinal cord that contributes to early maintenance of tactile allodynia.
Journal: Pain 20030101
Title: Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells.
Journal: Placenta 20030101
Title: The influence of a cyclooxygenase-1 inhibitor on injured and uninjured ligaments in the rat.
Journal: The American journal of sports medicine 20030101
Title: Both selective COX-1 and COX-2 inhibitors aggravate gastric damage induced in rats by 2-deoxy-D-glucose. relation to gastric hypermotility and COX-2 expression.
Journal: Digestion 20030101
Title: COX-2-derived prostacyclin mediates opioid-induced late phase of preconditioning in isolated rat hearts.
Journal: American journal of physiology. Heart and circulatory physiology 20021201
Title: The effects of cyclooxygenase isozyme inhibition on incisional wound healing in mouse skin.
Journal: The Journal of investigative dermatology 20021101
Title: Diesel exhaust particle extracts and associated polycyclic aromatic hydrocarbons inhibit Cox-2-dependent prostaglandin synthesis in murine macrophages and fibroblasts.
Journal: The Journal of biological chemistry 20021018
Title: Distinct roles for cyclooxygenases 1 and 2 in interleukin-1-induced behavioral changes.
Journal: The Journal of pharmacology and experimental therapeutics 20020901
Title: COX and NOS isoforms involved in acid-induced duodenal bicarbonate secretion in rats.
Journal: Digestive diseases and sciences 20020901
Title: Cyclooxygenase-1-selective inhibition prolongs gestation in mice without adverse effects on the ductus arteriosus.
Journal: The Journal of clinical investigation 20020815
Title: The skin fungus-induced Th1- and Th2-related cytokine, chemokine and prostaglandin E2 production in peripheral blood mononuclear cells from patients with atopic dermatitis and psoriasis vulgaris.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020801
Title: COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice.
Journal: Gastroenterology 20020601
Title: Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction.
Journal: Circulation 20020423
Title: Effects of cyclooxygenase-1/cyclooxygenase-2 inhibition on leukocyte/endothelial cell interactions in the rat mesentery.
Journal: European journal of pharmacology 20020405
Title: The role of cyclooxygenase-1 and -2 in the rat formalin test.
Journal: Anesthesia and analgesia 20020401
Title: COX-2 inhibition attenuates anorexia during systemic inflammation without impairing cytokine production.
Journal: American journal of physiology. Endocrinology and metabolism 20020301
Title: Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage.
Journal: The Journal of pharmacology and experimental therapeutics 20020301
Title: Involvement of peripheral cyclooxygenase-1 and cyclooxygenase-2 in inflammatory pain.
Journal: The Journal of pharmacy and pharmacology 20020301
Title: Cyclooxygenase-1 derived prostaglandins are involved in the maintenance of renal function in rats with cirrhosis and ascites.
Journal: British journal of pharmacology 20020201
Title: Selective inhibition of COX-2 is beneficial to mice infected intranasally with VSV.
Journal: Prostaglandins & other lipid mediators 20020201
Title: Mechanism of inhibition of novel COX-2 inhibitors.
Journal: Advances in experimental medicine and biology 20020101
Title: LPS-induced synthesis and release of PGE2 in liver macrophages: regulation by CPLA2, COX-1, COX-2, and PGE2 synthase.
Journal: Advances in experimental medicine and biology 20020101
Title: COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201
Title: Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord.
Journal: Journal of neurochemistry 20011101
Title: The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Title: Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.
Journal: The Journal of clinical investigation 20010815
Title: Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP.
Journal: American journal of physiology. Cell physiology 20010801
Title: A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors.
Journal: The Biochemical journal 20010801
Title: Cholera toxin induces prostaglandin synthesis via post-transcriptional activation of cyclooxygenase-2 in the rat jejunum.
Journal: The Journal of pharmacology and experimental therapeutics 20010601
Title: Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge.
Journal: British journal of pharmacology 20010401
Title: Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation.
Journal: Circulation research 20010330
Title: Disturbance of peristalsis in the guinea-pig isolated small intestine by indomethacin, but not cyclo-oxygenase isoform-selective inhibitors.
Journal: British journal of pharmacology 20010301
Title: Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010101
Title: Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs.
Journal: Journal of physiology, Paris 20010101
Title: Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs.
Journal: Neuroimmunomodulation 20010101
Title: Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13313-8.
Title: Lampiasi N, et al. The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells. Int J Mol Med. 2006 Feb;17(2):245-52.
Title: Teng XW, et al. Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat. J Pharm Pharm Sci. 2003 May-Aug;6(2):205-10.
