Home Other Building Blocks 189188-57-6
189188-57-6,MFCD04116201
Catalog No.:AA002HY3

189188-57-6 | Tegaserod maleate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%
in stock  
$6.00   $4.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002HY3
Chemical Name:
Tegaserod maleate
CAS Number:
189188-57-6
Molecular Formula:
C20H27N5O5
Molecular Weight:
417.4589
MDL Number:
MFCD04116201
SMILES:
OC(=O)/C=C\C(=O)O.CCCCCNC(=N)NN=Cc1c[nH]c2c1cc(OC)cc2
NSC Number:
760425
Properties
Computed Properties
 
Complexity:
504  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
10  

Downstream Synthesis Route

[1]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2005/272802,2005,A1Locationinpatent:Page/Pagecolumn2-3

[2]CurrentPatentAssignee:HETERODRUGSLIMITED-WO2004/85393,2004,A1Locationinpatent:Page4

[3]CurrentPatentAssignee:HETERODRUGSLIMITED-WO2004/85393,2004,A1Locationinpatent:Page5

[4]CurrentPatentAssignee:HETERODRUGSLIMITED-WO2004/85393,2004,A1Locationinpatent:Page5

2-(5-methoxy-1H-indol-3-yl)methylene-N-pentylhydrazinecarboximidamideD-(+)-camphorsulphonate 
  110-16-7    189188-57-6 

[1]CurrentPatentAssignee:GRUPOINSUD-EP1956002,2008,A1Locationinpatent:Page/Pagecolumn4

Literature

Title: A E Vickers, et al. In vitro metabolism of tegaserod in human liver and intestine: assessment of drug interactions. Drug Metab Dispos. 2001 Oct;29(10):1269-76.

Title: T C Seerden, et al. Experimental pancreatitis disturbs gastrointestinal and colonic motility in mice: effect of the prokinetic agent tegaserod. Neurogastroenterol Motil. 2007 Oct;19(10):856-64.

Title: M D Crowell, et al. The effects of tegaserod, a 5-HT receptor agonist, on gastric emptying in a murine model of diabetes mellitus. Neurogastroenterol Motil. 2005 Oct;17(5):738-43.

Title: H-C Pan, et al. Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice. Neuroscience. 2014 Sep 26;277:356-66.

Title: D T Beattie, et al. The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. Br J Pharmacol. 2004 Nov;143(5):549-60.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 189188-57-6
Tags:189188-57-6 Molecular Formula|189188-57-6 MDL|189188-57-6 SMILES|189188-57-6 Tegaserod maleate