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1893-33-0,MFCD00242979
Catalog No.:AA00AK55

1893-33-0 | Pipamperone

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Purity
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25mg
98%
in stock  
$693.00   $485.00
- +
100mg
98%
in stock  
$2,075.00   $1,453.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AK55
Chemical Name:
Pipamperone
CAS Number:
1893-33-0
Molecular Formula:
C21H30FN3O2
Molecular Weight:
375.4802
MDL Number:
MFCD00242979
SMILES:
O=C(c1ccc(cc1)F)CCCN1CCC(CC1)(N1CCCCC1)C(=O)N
NSC Number:
759178
Properties
Computed Properties
 
Complexity:
506  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
2  

Literature

Title: Effectiveness and tolerability of transdermal rivastigmine in the treatment of Alzheimer's disease in daily practice.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Auditing clinical outcomes after introducing off-licence prescribing of atypical antipsychotic melperone for patients with treatment refractory schizophrenia.

Journal: TheScientificWorldJournal 20120101

Title: Citalopram plus low-dose pipamperone versus citalopram plus placebo in patients with major depressive disorder: an 8-week, double-blind, randomized study on magnitude and timing of clinical response.

Journal: Psychological medicine 20111001

Title: [Loss of visual acuity after treatment with pipamperone].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20110801

Title: [A patient suffering from priapism as a side-effect of pipamperone].

Journal: Nederlands tijdschrift voor geneeskunde 20110101

Title: Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.

Journal: Dialogues in clinical neuroscience 20100901

Title: Identification and quantification of 30 antipsychotics in blood using LC-MS/MS.

Journal: Journal of mass spectrometry : JMS 20100801

Title: A field study on 8 pharmaceuticals and 1 pesticide in Belgium: removal rates in waste water treatment plants and occurrence in surface water.

Journal: The Science of the total environment 20100715

Title: Analysis of risperidone and its metabolite in plasma and saliva by LC with coulometric detection and a novel MEPS procedure.

Journal: Talanta 20100615

Title: Gene expression of NMDA receptor subunits in the cerebellum of elderly patients with schizophrenia.

Journal: European archives of psychiatry and clinical neuroscience 20100301

Title: Clinical trials in CNS--SMi's eighth annual conference.

Journal: IDrugs : the investigational drugs journal 20100201

Title: Rationale and design of the randomised clinical trial comparing early medication change (EMC) strategy with treatment as usual (TAU) in patients with major depressive disorder--the EMC trial.

Journal: Trials 20100101

Title: Increased D-amino acid oxidase expression in the bilateral hippocampal CA4 of schizophrenic patients: a post-mortem study.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091201

Title: Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20090901

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Antipsychotics and risk of venous thromboembolism: A population-based case-control study.

Journal: Clinical epidemiology 20090101

Title: Evaluation of serotonin-2A receptor occupancy with 123I-5-I-R91150 and single-photon emission tomography before and after low-dose pipamperone administration in the canine brain.

Journal: Nuclear medicine communications 20080801

Title: Comparison of matrix effects in HPLC-MS/MS and UPLC-MS/MS analysis of nine basic pharmaceuticals in surface waters.

Journal: Journal of the American Society for Mass Spectrometry 20080501

Title: [Recurrent dysregulation of body temperature during antipsychotic pharmacotherapy].

Journal: Psychiatrische Praxis 20080301

Title: Validation of a solid-phase extraction and liquid chromatography-electrospray tandem mass spectrometric method for the determination of nine basic pharmaceuticals in wastewater and surface water samples.

Journal: Journal of chromatography. A 20080227

Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal: Journal of medicinal chemistry 20080124

Title: [Pipamperone and the treatment of impulsive aggressive behaviour].

Journal: Tijdschrift voor psychiatrie 20080101

Title: The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913).

Journal: BMC psychiatry 20080101

Title: [Enuresis in therapy with psychotropic drugs].

Journal: Praxis 20070905

Title: Hypothermia following antipsychotic drug use.

Journal: European journal of clinical pharmacology 20070601

Title: Forty years of antipsychotic Drug research--from haloperidol to paliperidone--with Dr. Paul Janssen.

Journal: Arzneimittel-Forschung 20070101

Title: Influence of the antipsychotic drug pipamperone on the expression of the dopamine D4 receptor.

Journal: Life sciences 20061203

Title: Management of a severe forceful breather with Rett syndrome using carbogen.

Journal: Brain & development 20061101

Title: Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020

Title: Tackling matrix effects during development of a liquid chromatographic-electrospray ionisation tandem mass spectrometric analysis of nine basic pharmaceuticals in aqueous environmental samples.

Journal: Journal of chromatography. A 20060804

Title: [Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations].

Journal: No to shinkei = Brain and nerve 20060601

Title: Stability indicating LC method for the determination of pipamperone.

Journal: Journal of pharmaceutical and biomedical analysis 20051004

Title: Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling.

Journal: BMC bioinformatics 20050101

Title: In-patient psychiatric-psychotherapeutic treatment of mothers with a generalized anxiety disorder--does the co-admission of their children influence the treatment results? A prospective, controlled study.

Journal: Wiener klinische Wochenschrift 20041130

Title: Therapeutic drug monitoring of 13 antidepressant and five neuroleptic drugs in serum with liquid chromatography-electrospray ionization mass spectrometry.

Journal: Clinical chemistry and laboratory medicine 20031201

Title: Quantitative determination of piritramide in human serum applying liquid chromatography-two-stage mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

Title: Differential-pulse polarography determination of pipamperone in pharmaceutical formulations.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: Role of 5-HT(2) receptors in the tryptamine-induced 5-HT syndrome in rats.

Journal: Behavioural pharmacology 20020701

Title: Immunoassay screening of lysergic acid diethylamide (LSD) and its confirmation by HPLC and fluorescence detection following LSD ImmunElute extraction.

Journal: Journal of analytical toxicology 20020401

Title: [Models of drug treatment in the attention deficit disorder with hyperactivity].

Journal: Revista de neurologia 20020201

Title: Atypical kinetics for a series of putative dopamine antagonists to reverse the low-magnitude Ca2+ phase in the dopamine-bound D2short receptor state.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020101

Title: Pharmacokinetics of pipamperone from three different tablet formulations.

Journal: Arzneimittel-Forschung 20020101

Title: Different regulation of rat 5-HT(2A) and rat 5-HT(2C) receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone.

Journal: European journal of pharmacology 20010803

Title: Antipsychotic-induced extrapyramidal syndromes. Risperidone compared with low- and high-potency conventional antipsychotic drugs.

Journal: European journal of clinical pharmacology 20010701

Title: Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome.

Journal: Brain research 20010126

Title: Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.

Journal: Psychopharmacology 19960301

Title: Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone.

Journal: Arzneimittel-Forschung 19940301

Title: Erik Buntinx, MD, et al. Selective Serotonergic Properties of Low-Dose Pipamperone May Enhance Antidepressant Effect: Preclinical Evidence.

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