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1903008-80-9,MFCD31728331
Catalog No.:AA01EAZH

1903008-80-9 | Lazertinib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$19.00   $14.00
- +
5mg
97%
in stock  
$47.00   $33.00
- +
50mg
97%
in stock  
$195.00   $137.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EAZH
Chemical Name:
Lazertinib
CAS Number:
1903008-80-9
Molecular Formula:
C30H34N8O3
Molecular Weight:
554.6428
MDL Number:
MFCD31728331
SMILES:
C=CC(=O)Nc1cc(Nc2nccc(n2)n2cc(c(n2)c2ccccc2)CN(C)C)c(cc1N1CCOCC1)OC
Properties
Computed Properties
 
Complexity:
837  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
XLogP3:
3.4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:YUHANCORPORATION-WO2018/194356,2018,A1Locationinpatent:Paragraph94;95;96;97

[1]CurrentPatentAssignee:YUHANCORPORATION-WO2018/194356,2018,A1Locationinpatent:Paragraph85;86;87;88;89

[2]CurrentPatentAssignee:HANGZHOUSOLIPHARMA-WO2022/253261,2022,A1Locationinpatent:Page/Pagecolumn11

[1]CurrentPatentAssignee:YUHANCORPORATION-WO2018/194356,2018,A1Locationinpatent:Paragraph98;99;100;101;102

594-45-6   
N-(5-((4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-yl)amino)-4-methoxy-2-morpholinophenyl)acrylamide 
 
(x)C6H8O7*C30H34N8O3 

[1]CurrentPatentAssignee:YUHANCORPORATION-WO2018/194356,2018,A1Locationinpatent:Paragraph103;104;105;106

Literature

Title: Byoung Chul Cho, et al. YH25448, a 3rd Generation EGFR-TKI, in Patients with EGFR-TKI-resistant NSCLC: Phase I/II Study Results.

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SDS
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Tags:1903008-80-9 Molecular Formula|1903008-80-9 MDL|1903008-80-9 SMILES|1903008-80-9 Lazertinib