Catalog No.:AA01JPAR

1903768-17-1 | (2S,4R)-1-{[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide

Name: Name:(2S,4R)-1-{[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide
Brand: AABLOCKS
SKU: AA01JPAR
Availability: InStock
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1mg

≥98%

in stock

$132.00 $92.00

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5mg

99%

in stock

$543.00 $380.00

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10mg

≥98%

in stock

$1,016.00 $711.00

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25mg

99%

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$1,359.00 $952.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
Request for Quotation
Download SDS

Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA01JPAR

Chemical Name:

(2S,4R)-1-{[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide

CAS Number:

1903768-17-1

Molecular Formula:

C26H23BrFN7O3

Molecular Weight:

580.4083

MDL Number:

MFCD01018179

SMILES:

FC1CN(C(C1)C(=O)Nc1cccc(n1)Br)C(=O)Cn1nc(c2c1ccc(c2)c1cnc(nc1)C)C(=O)C

Properties

Downstream Synthesis Route

2086183-73-3

1903768-17-1

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2017/35353,2017,A1

1903745-22-1

2086187-41-7

1903768-17-1

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2017/35353,2017,A1Locationinpatent:Paragraph1157;1602

2086187-40-6

1903768-17-1

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2017/35353,2017,A1

[2]CurrentPatentAssignee:ASTRAZENECAPLC-WO2021/183555,2021,A1

201227-39-6

1903768-17-1

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2017/35353,2017,A1

[2]CurrentPatentAssignee:ASTRAZENECAPLC-WO2017/35353,2017,A1

1903768-17-1

2086178-78-9

2086178-79-0

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2017/35353,2017,A1Locationinpatent:Paragraph1158;1159;1160

Literature

Title: Yuan X, et al. Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. Haematologica. 2017 Mar;102(3):466-475.

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SDS

1903768-17-1 | (2S,​4R)​-​1-​{[3-​acetyl-​5-​(2-​methylpyrimidin-​5-​yl)​-​1H-​indazol-​1-​yl]​acetyl}​-​N-​(6-​bromopyridin-​2-​yl)​-​4-​fluoropyrrolidine-​2-​carboxamide

1903768-17-1 | (2S,4R)-1-{[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide