Title: Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601
Title: A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101
Title: The logic of strategic ignorance.
Journal: The British journal of sociology 20120901
Title: Synthesis and antibacterial activity of desosamine-modified macrolide derivatives.
Journal: Bioorganic & medicinal chemistry letters 20120715
Title: Active safety monitoring of newly marketed medications in a distributed data network: application of a semi-automated monitoring system.
Journal: Clinical pharmacology and therapeutics 20120701
Title: Transport characteristics of clarithromycin, azithromycin and telithromycin, antibiotics applied for treatment of respiratory infections, in Calu-3 cell monolayers as model lung epithelial cells.
Journal: Die Pharmazie 20120501
Title: Predicting drug interaction potential with a physiologically based pharmacokinetic model: a case study of telithromycin, a time-dependent CYP3A inhibitor.
Journal: Clinical pharmacology and therapeutics 20120401
Title: Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens.
Journal: Bioorganic & medicinal chemistry letters 20120101
Title: Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.
Journal: Journal of clinical pharmacology 20120101
Title: Understanding the regulatory hurdles for antibacterial drug development in the post-Ketek world.
Journal: Annals of the New York Academy of Sciences 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Alterations in regulatory regions of erm(B) genes from clinical isolates of enterococci resistant to telithromycin.
Journal: Archives of pharmacal research 20111201
Title: Anti-inflammatory effects of garenoxacin on IL-8 production and ERK1/2 activation induced by lipopolysaccharides in A549 and THP-1 cells.
Journal: European journal of pharmacology 20111001
Title: Total synthesis of (-)-4,8,10-tridesmethyl telithromycin.
Journal: The Journal of organic chemistry 20110916
Title: Clarithromycin and telithromycin increases interleukin-10 expression in the rat endometriosis model.
Journal: Cytokine 20110901
Title: Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones.
Journal: European journal of medicinal chemistry 20110801
Title: [Influence of a regulatory safety warning on the use of telithromycin].
Journal: Medicina clinica 20110416
Title: Synthesis and antibacterial activity of novel ketolides with 11,12-sulfur contained aryl alkyl side chains.
Journal: European journal of medicinal chemistry 20110101
Title: Differences in clinical features according to Boryoung and Karp genotypes of Orientia tsutsugamushi.
Journal: PloS one 20110101
Title: Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials.
Journal: Bioorganic & medicinal chemistry 20101215
Title: Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Degradation kinetics of telithromycin determined by HPLC method.
Journal: Journal of chromatographic science 20101101
Title: 4''-O-(omega-Quinolylamino-alkylamino)propionyl derivatives of selected macrolides with the activity against the key erythromycin resistant respiratory pathogens.
Journal: Bioorganic & medicinal chemistry 20100901
Title: 6-Alkylquinolone-3-carboxylic acid tethered to macrolides synthesis and antimicrobial profile.
Journal: Bioorganic & medicinal chemistry 20100901
Title: Synthesis and properties of macrolones characterized by two ether bonds in the linker.
Journal: Bioorganic & medicinal chemistry 20100901
Title: Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides.
Journal: Journal of medicinal chemistry 20100812
Title: Detection of a new erm(X)-mediated antibiotic resistance in Egyptian cutaneous propionibacteria.
Journal: Anaerobe 20100801
Title: Disposition of oral telithromycin in foals and in vitro activity of the drug against macrolide-susceptible and macrolide-resistant Rhodococcus equi isolates.
Journal: Journal of veterinary pharmacology and therapeutics 20100801
Title: Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections.
Journal: Drug development and industrial pharmacy 20100701
Title: Mutational analysis of reduced telithromycin susceptibility of Streptococcus pneumoniae isolated clinically in Japan.
Journal: FEMS microbiology letters 20100601
Title: Novel 8a-aza-8a-homoerythromycin--4''-(3-substituted-amino)propionates with broad spectrum antibacterial activity.
Journal: Bioorganic & medicinal chemistry letters 20100601
Title: Neuropsychological effects of macrolides.
Journal: Prescrire international 20100601
Title: Telithromycin blocks neuromuscular transmission and inhibits nAChR currents in vitro.
Journal: Toxicology letters 20100504
Title: Novel azalides derived from 16-membered macrolides. III. Azalides modified at the C-15 and 4'' positions: Improved antibacterial activities.
Journal: Bioorganic & medicinal chemistry 20100401
Title: [Investigation of macrolide-lincosamide-streptogramin B (MLS(B)) and telithromycin resistance in clinical strains of staphylococci].
Journal: Mikrobiyoloji bulteni 20100401
Title: Telithromycin: visual disorders.
Journal: Prescrire international 20100401
Title: Pharmacokinetic interaction between telithromycin and metformin in diabetes mellitus rats.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100301
Title: Effect of telithromycin on the pharmacokinetics and pharmacodynamics of oral oxycodone.
Journal: Journal of clinical pharmacology 20100101
Title: In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms.
Journal: Antimicrobial agents and chemotherapy 20100101
Title: Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics.
Journal: Current topics in medicinal chemistry 20100101
Title: Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages.
Journal: The Journal of pharmacy and pharmacology 20100101
Title: Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.
Journal: Journal of medicinal chemistry 20091210
Title: Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells.
Journal: Pulmonary pharmacology & therapeutics 20091201
Title: Macrolides, ketolides, and glycylcyclines: azithromycin, clarithromycin, telithromycin, tigecycline.
Journal: Infectious disease clinics of North America 20091201
Title: Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: Pharmacodynamic target attainment potential of azithromycin, clarithromycin, and telithromycin in serum and epithelial lining fluid of community-acquired pneumonia patients with penicillin-susceptible, intermediate, and resistant Streptococcus pneumoniae.
Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20090701
Title: Multiple-dose pharmacokinetics of telithromycin in peripheral soft tissues.
Journal: International journal of antimicrobial agents 20090701
Title: Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.
Journal: Toxicology and applied pharmacology 20090615
Title: New antimicrobial molecules and new antibiotic strategies.
Journal: Seminars in respiratory and critical care medicine 20090401
Title: Antibacterial activity of telithromycin and comparators against pathogens isolated from patients with community-acquired respiratory tract infections: the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin study year 5 (2003-2004).
Journal: Diagnostic microbiology and infectious disease 20090301
Title: LC method for telithromycin in tablets: a stability-indicating assay.
Journal: International journal of pharmaceutics 20090121
Title: Different effects of telithromycin on MUC5AC production induced by human neutrophil peptide-1 or lipopolysaccharide in NCI-H292 cells compared with azithromycin and clarithromycin.
Journal: The Journal of antimicrobial chemotherapy 20090101
Title: Telithromycin-associated hepatotoxicity: Clinical spectrum and causality assessment of 42 cases.
Journal: Hepatology (Baltimore, Md.) 20090101
Title: Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: [Pneumonia in a traveller coming back from Asia].
Journal: Medecine et maladies infectieuses 20081201
Title: Time-dependent effects of Klebsiella pneumoniae endotoxin on the telithromycin pharmacokinetics in rats; restoration of the parameters in 96-hour KPLPS rats to the control levels.
Journal: Pulmonary pharmacology & therapeutics 20081201
Title: Risk of hepatotoxicity associated with the use of telithromycin: a signal detection using data mining algorithms.
Journal: The Annals of pharmacotherapy 20081201
Title: A ketolide antibiotic, telithromycin, inhibits vascular adrenergic neurotransmission in the rat mesenteric vascular bed.
Journal: British journal of pharmacology 20081101
Title: In vitro compared activity of telithromycin and azithromycin against northwest Italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility.
Journal: Letters in applied microbiology 20081001
Title: Cellular imaging predictions of clinical drug-induced liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080901
Title: Telithromycin pharmacokinetics in rat model of diabetes mellitus induced by alloxan or streptozotocin.
Journal: Pharmaceutical research 20080801
Title: Telithromycin inhibits the production of proinflammatory mediators and the activation of NF-kappaB in in vitro-stimulated murine cells.
Journal: FEMS immunology and medical microbiology 20080801
Title: The intracellular accumulation of phagocytic and epithelial cells and the inhibitory effect on Chlamydophila (Chlamydia) pneumoniae of telithromycin and comparator antimicrobials.
Journal: Journal of chemotherapy (Florence, Italy) 20080801
Title: Effects of telithromycin in in vitro and in vivo models of lipopolysaccharide-induced airway inflammation.
Journal: Chest 20080701
Title: In vitro activity of telavancin against resistant gram-positive bacteria.
Journal: Antimicrobial agents and chemotherapy 20080701
Title: [New antibiotics].
Journal: La Revue de medecine interne 20080601
Title: Antimicrobial susceptibility of respiratory tract pathogens in Japan during PROTEKT years 1-5 (1999-2004).
Journal: Microbial drug resistance (Larchmont, N.Y.) 20080601
Title: Clinical efficacy and time to symptom resolution of 5-day telithromycin versus 10-day amoxicillin-clavulanate in the treatment of acute bacterial sinusitis.
Journal: Current medical research and opinion 20080601
Title: Subinhibitory concentrations of telithromycin, clarithromycin and azithromycin reduce methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo.
Journal: The Journal of antimicrobial chemotherapy 20080301
Title: Increasing telithromycin resistance among Streptococcus pyogenes in Europe.
Journal: The Journal of antimicrobial chemotherapy 20080301
Title: Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections.
Journal: Expert opinion on pharmacotherapy 20080201
Title: Telithromycin and the FDA: implications for the future.
Journal: The Lancet. Infectious diseases 20080201
Title: Levofloxacin-resistant Helicobacter pylori in Hong Kong.
Journal: Chemotherapy 20080101
Title: Elevated hepatic transaminases associated with telithromycin therapy: a case report and literature review.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080101
Title: Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4.
Journal: Annals of clinical microbiology and antimicrobials 20080101
Title: In vitro activity of telithromycin against Haemophilus influenzae at epithelial lining fluid concentrations.
Journal: BMC microbiology 20080101
Title: Benefit-risk assessment of telithromycin in the treatment of community-acquired pneumonia.
Journal: Drug safety 20080101
Title: [Susceptibility of Staphylococcus aureus to new macrolide antibiotics].
Journal: Przeglad lekarski 20080101
Title: Accessing FDA approval packages and briefing documents.
Journal: The Annals of pharmacotherapy 20071201
Title: Emergence of telithromycin resistance in Haemophilus influenzae in Japan.
Journal: Journal of medical microbiology 20071201
Title: [Recent results of multinational studies on antibiotic resistance: should we have 'PROTECTion' against these resistances?].
Journal: Medecine et maladies infectieuses 20071101
Title: Susceptibility of oral obligate anaerobes to telithromycin, moxifloxacin and a number of commonly used antibacterials.
Journal: Oral microbiology and immunology 20071001
Title: Susceptibilities of Streptococcus pyogenes and Streptococcus pneumoniae to macrolides and telithromycin: data from an Italian multicenter study.
Journal: Journal of chemotherapy (Florence, Italy) 20071001
Title: Novel tethers in ketolide antibiotics.
Journal: Bioorganic & medicinal chemistry letters 20070915
Title: Synthesis and antibacterial activity of C11, C12-cyclic urea analogues of ketolides.
Journal: Bioorganic & medicinal chemistry letters 20070915
Title: In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe.
Journal: Antimicrobial agents and chemotherapy 20070901
Title: Regional trends in beta-lactam, macrolide, fluoroquinolone and telithromycin resistance among Streptococcus pneumoniae isolates 2001-2004.
Journal: The Journal of infection 20070801
Title: Acute hepatitis attack after exposure to telithromycin.
Journal: Clinical therapeutics 20070801
Title: Activity of telithromycin and comparators against isolates of Legionella pneumophila collected from patients with community-acquired respiratory tract infections: PROTEKT Years 1-5.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070701
Title: Activities of clindamycin, synercid, telithromycin, linezolid, and mupirocin against Gram-positive coccal strains resistant to erythromycin in Korea.
Journal: Archives of pharmacal research 20070701
Title: Activities of 16-membered ring macrolides and telithromycin against different genotypes of erythromycin-susceptible and erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20070601
Title: Telithromycin: the perils of hasty adoption and persistence of off-label prescribing.
Journal: Journal of managed care pharmacy : JMCP 20070601
Title: Effective integration of medical and pharmacy claims to better protect patient safety--a long road yet to travel.
Journal: Journal of managed care pharmacy : JMCP 20070601
Title: The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070501
Title: EDP-420, a bicyclolide (bridged bicyclic macrolide), is active against Mycobacterium avium.
Journal: Antimicrobial agents and chemotherapy 20070501
Title: Effects of acute renal failure on the pharmacokinetics of telithromycin in rats: negligible effects of increase in CYP3A1 on the metabolism of telithromycin.
Journal: Biopharmaceutics & drug disposition 20070501
Title: The FDA and the case of Ketek.
Journal: The New England journal of medicine 20070419
Title: Ketek--the FDA perspective.
Journal: The New England journal of medicine 20070419
Title: Resistance phenotypes conferred by macrolide phosphotransferases.
Journal: FEMS microbiology letters 20070401
Title: Re: Acute bacterial rhinosinusitis--a review of US treatment guidelines.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070401
Title: Comparative in vitro and bactericidal activities of telithromycin against penicillin-nonsusceptible, levofloxacin-resistant, and macrolide-resistant Streptococcus pneumoniae by time-kill methodology.
Journal: International journal of antimicrobial agents 20070301
Title: The anti-inflammatory activity of telithromycin in a mouse model of septic shock.
Journal: International journal of antimicrobial agents 20070301
Title: Telithromycin-induced TEN: report of a case.
Journal: Archives of dermatology 20070301
Title: [Macrolides and ketolides].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20070227
Title: Role for 5-day, once-daily extended-release clarithromycin in acute bacterial exacerbation of chronic bronchitis.
Journal: Current medical research and opinion 20070201
Title: In vitro activities of oral cephem and telithromycin against clinical isolates of major respiratory pathogens in Japan.
Journal: Journal of Korean medical science 20070201
Title: Recent findings from multinational resistance surveys: are we 'PROTEKTed' from resistance?
Journal: International journal of antimicrobial agents 20070201
Title: The first telithromycin-resistant Streptococcus pneumoniae isolate in Japan associated with erm(B) and mutations in 23S rRNA and riboprotein L4.
Journal: Japanese journal of infectious diseases 20070201
Title: Leber's hereditary optic neuropathy associated with cocaine, ecstasy and telithromycin consumption.
Journal: Journal of neurology 20070201
Title: Limit Ketek to pneumonia, experts advise: advisers urge black-box warning.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070115
Title: Pharmacokinetics of telithromycin using bronchoscopic microsampling after single and multiple oral doses.
Journal: Pulmonary pharmacology & therapeutics 20070101
Title: Human serum activity of telithromycin, azithromycin and amoxicillin/clavulanate against common aerobic and anaerobic respiratory pathogens.
Journal: International journal of antimicrobial agents 20070101
Title: Telithromycin inhibits the number of viable bacteria but not lymphocyte accumulation in a murine model of chronic respiratory infection.
Journal: Chemotherapy 20070101
Title: Apparent anaphylactoid reaction after treatment with a single dose of telithromycin.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070101
Title: Time-kill kinetics of Streptococcus pneumoniae with reduced susceptibility to telithromycin.
Journal: Chemotherapy 20070101
Title: [In vitro susceptibility of respiratory isolates of Streptococcus pneumoniae and Streptococcus pyogenes to telithromycin and 11 other antimicrobial agents: Turkish results of e-BASKETT-II surveillance study].
Journal: Mikrobiyoloji bulteni 20070101
Title: Dose-dependent pharmacokinetics of telithromycin after intravenous and oral administration to rats: contribution of intestinal first-pass effect to low bioavailability.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101
Title: Comparative activities of antibiotics against intracellular non-typeable Haemophilus influenzae.
Journal: Wiener klinische Wochenschrift 20070101
Title: Telithromycin use and spontaneous reports of hepatotoxicity.
Journal: Drug safety 20070101
Title: Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies.
Journal: Clinical pharmacokinetics 20070101
Title: In vitro activity of telithromycin and quinupristin/dalfopristin against methicillin-resistant coagulase-negative staphylococci with defined resistance genotypes.
Journal: Folia microbiologica 20070101
Title: Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment.
Journal: Neurology 20061226
Title: Synthesis and antibacterial activity of C6-carbazate ketolides.
Journal: Bioorganic & medicinal chemistry letters 20061215
Title: Telithromycin and myasthenic crisis.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061215
Title: Telithromycin and acute liver failure.
Journal: The New England journal of medicine 20061123
Title: Severe hepatotoxicity of telithromycin.
Journal: Annals of internal medicine 20060919
Title: In vitro effects of penicillin and telithromycin on the expression of Streptococcus pneumoniae capsule.
Journal: The Journal of antimicrobial chemotherapy 20060901
Title: In vivo efficacy of telithromycin on cytokine and nitric oxide formation in lipopolysaccharide-induced acute systemic inflammation in mice.
Journal: The Journal of antimicrobial chemotherapy 20060901
Title: Treatment of experimental chronic pulmonary mycoplasmosis.
Journal: International journal of antimicrobial agents 20060901
Title: Synthesis and antibacterial activity of novel C12 ethyl ketolides.
Journal: Bioorganic & medicinal chemistry 20060815
Title: Telithromycin in acute exacerbations of asthma.
Journal: The New England journal of medicine 20060706
Title: Telithromycin in acute exacerbations of asthma.
Journal: The New England journal of medicine 20060706
Title: Telithromycin in acute exacerbations of asthma.
Journal: The New England journal of medicine 20060706
Title: Telithromycin in acute exacerbations of asthma.
Journal: The New England journal of medicine 20060706
Title: Investigation of inducible clindamycin and telithromycin resistance in isolates of beta-hemolytic streptococci.
Journal: Diagnostic microbiology and infectious disease 20060701
Title: Differentiation of arrhythmia risk of the antibacterials moxifloxacin, erythromycin, and telithromycin based on analysis of monophasic action potential duration alternans and cardiac instability.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: [Successful telithromycin therapy of Legionella pneumonia --report of three cases].
Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20060701
Title: Old dogs that learn new tricks: modified antimicrobial agents that escape pre-existing resistance mechanisms.
Journal: International journal of medical microbiology : IJMM 20060601
Title: Telithromycin-induced digoxin toxicity and electrocardiographic changes.
Journal: Pharmacotherapy 20060601
Title: Pharmacodynamics: relation to antimicrobial resistance.
Journal: The American journal of medicine 20060601
Title: Pill esophagitis caused by telithromycin: a case report.
Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20060601
Title: A fine pile of paté: the cautionary tale of telithromycin, hepatic failure, and study 3014.
Journal: Surgical infections 20060601
Title: Telithromycin in lower respiratory tract infections.
Journal: Future microbiology 20060601
Title: Effect of a newly developed ketolide antibiotic, telithromycin, on metabolism of theophylline and expression of cytochrome P450 in rats.
Journal: Life sciences 20060530
Title: [Potential interaction between telitromicin and acenocumarol].
Journal: Medicina clinica 20060527
Title: Clinical implications and treatment of multiresistant Streptococcus pneumoniae pneumonia.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060501
Title: What's new in clinical pharmacology and therapeutics.
Journal: WMJ : official publication of the State Medical Society of Wisconsin 20060501
Title: Fraud, errors taint a key study of widely used Sanofi drug; despite some faked results, FDA approves antibiotic; one doctor's cocaine use; company defends safety.
Journal: Wall Street journal (Eastern ed.) 20060501
Title: The effect of telithromycin in acute exacerbations of asthma.
Journal: The New England journal of medicine 20060413
Title: Treating acute asthma with antibiotics--not quite yet.
Journal: The New England journal of medicine 20060413
Title: Clinical and bacteriologic efficacy of telithromycin in patients with bacteremic community-acquired pneumonia.
Journal: Respiratory medicine 20060401
Title: Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12-lactoketolides.
Journal: Bioorganic & medicinal chemistry letters 20060401
Title: Drug interactions during therapy with three major groups of antimicrobial agents.
Journal: Expert opinion on pharmacotherapy 20060401
Title: Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis.
Journal: Archives of otolaryngology--head & neck surgery 20060401
Title: In vivo immunomodulatory profile of telithromycin in a murine pneumococcal infection model.
Journal: Die Pharmazie 20060401
Title: Antibiotics for treatment of resistant gram-positive coccal infections.
Journal: Indian journal of pediatrics 20060401
Title: Summaries for patients. Telithromycin: a possible cause of severe liver damage?
Journal: Annals of internal medicine 20060321
Title: Brief communication: severe hepatotoxicity of telithromycin: three case reports and literature review.
Journal: Annals of internal medicine 20060321
Title: Telithromycin.
Journal: Annals of internal medicine 20060321
Title: In vitro activity of telithromycin against Gram-negative bacterial pathogens.
Journal: The Journal of infection 20060301
Title: Telithromycin in the treatment of pneumococcal community-acquired respiratory tract infections: a review.
Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20060301
Title: Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides.
Journal: Bioorganic & medicinal chemistry letters 20060301
Title: Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide.
Journal: Clinical pharmacology and therapeutics 20060301
Title: [Clinicoradiological diagnosis of respiratory infections: estimate of pathogens by radiological findings and the strategy for treatment].
Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20060301
Title: Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives.
Journal: Bioorganic & medicinal chemistry letters 20060215
Title: An in vitro study of the activity of telithromycin against mobile and cystic forms of Borrelia afzelii.
Journal: Infection 20060201
Title: Sampling the antibiotic resistome.
Journal: Science (New York, N.Y.) 20060120
Title: A review of guidelines for antibacterial use in acute exacerbations of chronic bronchitis.
Journal: Pulmonary pharmacology & therapeutics 20060101
Title: [Antimicrobial resistance of Streptococcus pneumoniae strains isolated in the Reunion Island during 2004].
Journal: Medecine et maladies infectieuses 20060101
Title: Microbiological assay for the determination of telithromycin in tablets.
Journal: Journal of AOAC International 20060101
Title: New safety information on Ketek.
Journal: FDA consumer 20060101
Title: Trends in anti-bacterial resistance among Streptococcus pneumoniae isolated in the USA, 2000-2003: PROTEKT US years 1-3.
Journal: The Journal of infection 20051201
Title: Resistance to telithromycin is conferred by msr(A), msrC and msr(D) in Staphylococcus aureus.
Journal: The Journal of antimicrobial chemotherapy 20051201
Title: Susceptibility of Streptococcus pneumoniae to penicillin, azithromycin and telithromycin (PROTEKT 1999-2003).
Journal: International journal of antimicrobial agents 20051201
Title: Activity of five quinolones, three macrolides and telithromycin against 12 Haemophilus influenzae strains with different resistance phenotypes.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20051201
Title: Activity of telithromycin against thirteen new isolates of C. burnetii including three resistant to doxycycline.
Journal: Annals of the New York Academy of Sciences 20051201
Title: Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis.
Journal: The Journal of biological chemistry 20051125
Title: The PROTEKT global study (year 4) demonstrates a continued lack of resistance development to telithromycin in Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20051001
Title: Resistance to macrolides, clindamycin and telithromycin in Streptococcus pyogenes isolated in Spain during 2004.
Journal: The Journal of antimicrobial chemotherapy 20051001
Title: Evaluation of telithromycin against Streptococcus pneumoniae with ribosomal mutations utilizing in vitro time-kill methodology.
Journal: International journal of antimicrobial agents 20051001
Title: Intrapulmonary concentrations of telithromycin: clinical implications for respiratory tract infections due to Streptococcus pneumoniae.
Journal: Chemotherapy 20051001
Title: Efficacy of oral telithromycin in community-acquired pneumonia caused by resistant Streptococcus pneumoniae.
Journal: The Journal of infection 20051001
Title: Five-day telithromycin once daily is as effective as 10-day clarithromycin twice daily for the treatment of acute exacerbations of chronic bronchitis and is associated with reduced health-care resource utilization.
Journal: Chest 20051001
Title: Pharmacokinetics of telithromycin: application to dosing in the treatment of community-acquired respiratory tract infections.
Journal: Current medical research and opinion 20051001
Title: [Efficacy and safety of extended-release clarithromycin (5-day short-course) vs telithromycin, in acute bacterial exacerbation of chronic bronchitis].
Journal: Medecine et maladies infectieuses 20051001
Title: In vitro activity of beta-lactams, macrolides, telithromycin, and fluoroquinolones against clinical isolates of Streptococcus pneumoniae: correlation between drug resistance and genetic characteristics.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20051001
Title: Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20051001
Title: Activity of telithromycin against multi-drug resistant Streptococcus pneumoniae and molecular characterization of macrolide and tetracycline resistance determinants.
Journal: Journal of chemotherapy (Florence, Italy) 20051001
Title: Mechanisms of resistance to telithromycin in Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20050901
Title: Demographic analysis of antimicrobial resistance among Streptococcus pneumoniae: worldwide results from PROTEKT 1999-2000.
Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20050901
Title: Amoxicillin/telithromycin-induced rash in infectious mononucleosis.
Journal: The Annals of pharmacotherapy 20050901
Title: Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations.
Journal: The Journal of antimicrobial chemotherapy 20050901
Title: The bioequivalence of telithromycin administered orally as crushed tablets versus tablets swallowed whole.
Journal: Journal of clinical pharmacology 20050901
Title: Comparative pharmacodynamics of telithromycin and clarithromycin with Streptococcus pneumoniae and Staphylococcus aureus in an in vitro dynamic model: focus on clinically achievable antibiotic concentrations.
Journal: International journal of antimicrobial agents 20050901
Title: Telithromycin for the treatment of acute bacterial maxillary sinusitis: a review of a new antibacterial agent.
Journal: Southern medical journal 20050901
Title: [Efficacy and safety of telithromycin in the treatment of acute exacerbation of chronic obstructive pulmonary disease].
Journal: Medecine et maladies infectieuses 20050901
Title: [Implication of ermX genes in macrolide- and telithromycin-resistance in Corynebacterium jeikeium and Corynebacterium amycolatum].
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20050901
Title: Telithromycin-resistant Streptococcus pneumoniae.
Journal: Emerging infectious diseases 20050901
Title: Determination of telithromycin in human plasma and microdialysates by high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805
Title: Assessment of the effect of a single oral dose of telithromycin on sotalol-induced qt interval prolongation in healthy women.
Journal: British journal of clinical pharmacology 20050801
Title: Telithromycin: the first ketolide antimicrobial.
Journal: Clinical therapeutics 20050801
Title: Impact of carbon dioxide on the susceptibility of key respiratory tract pathogens to telithromycin and azithromycin.
Journal: The Journal of antimicrobial chemotherapy 20050701
Title: In vitro activity of telithromycin against respiratory tract pathogens in comparison with other antimicrobial agents.
Journal: Chemotherapy 20050701
Title: Efficacy of telithromycin in community-acquired pneumonia caused by pneumococci with reduced susceptibility to penicillin and/or erythromycin.
Journal: Chemotherapy 20050701
Title: Telithromycin: a ketolide antibiotic for treatment of respiratory tract infections.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050601
Title: Assessment of the efficacy of telithromycin simulating human exposures against S. pneumoniae with ribosomal mutations in a murine pneumonia model.
Journal: International journal of antimicrobial agents 20050601
Title: Macrolide- and telithromycin-resistant Streptococcus pyogenes, Belgium, 1999-2003.
Journal: Emerging infectious diseases 20050601
Title: [In vitro antibacterial activities of telithromycin against clinical isolates of Neisseria gonorrhoeae].
Journal: The Japanese journal of antibiotics 20050601
Title: Telithromycin: do we really need this antimicrobial?
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050501
Title: Telithromycin: the first ketolide for the treatment of respiratory infections.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050501
Title: Pharmacodynamics of an 800-mg dose of telithromycin in patients with community-acquired pneumonia caused by extracellular pathogens.
Journal: Diagnostic microbiology and infectious disease 20050501
Title: Susceptibilities of Neisseria gonorrhoeae and Ureaplasma urealyticum isolates from male patients with urethritis to several antibiotics including telithromycin.
Journal: Chemotherapy 20050501
Title: Adverse drug reactions in Canada.
Journal: Canadian family physician Medecin de famille canadien 20050501
Title: Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Journal: Cell 20050422
Title: Telithromycin activity is reduced by efflux in Streptococcus pyogenes.
Journal: The Journal of antimicrobial chemotherapy 20050401
Title: Macrolide-resistance mechanisms in Streptococcus pneumoniae isolates from Belgium.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050401
Title: Penetration of telithromycin into the nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis.
Journal: The Journal of antimicrobial chemotherapy 20050401
Title: Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis.
Journal: The Journal of infection 20050401
Title: In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.
Journal: Antimicrobial agents and chemotherapy 20050401
Title: [Efficacy and safety of telithromycin in the treatment of acute maxillary sinusitis].
Journal: Medecine et maladies infectieuses 20050401
Title: [In vitro activity of telithromycin against community acquired respiratory pathogens].
Journal: Revista medica de Chile 20050401
Title: Synthesis and biological activity of new 5-O-sugar modified ketolide and 2-fluoro-ketolide antibiotics.
Journal: Bioorganic & medicinal chemistry letters 20050301
Title: Bacteriological efficacy of 5-day therapy with telithromycin in acute maxillary sinusitis.
Journal: International journal of antimicrobial agents 20050301
Title: Ketolides: new antimicrobials for community-acquired pneumonia.
Journal: Home healthcare nurse 20050301
Title: Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment.
Journal: International journal of clinical pharmacology and therapeutics 20050301
Title: Telithromycin for the treatment of acute exacerbations of chronic bronchitis.
Journal: International journal of clinical practice 20050301
Title: Verapamil toxicity resulting from a probable interaction with telithromycin.
Journal: The Annals of pharmacotherapy 20050201
Title: In vitro activity of telithromycin against mefA and ermB erythromycin-resistant viridans streptococci isolated from bacteremia of oral origin in Spain.
Journal: Oral microbiology and immunology 20050201
Title: Telithromycin new product overview.
Journal: The Journal of allergy and clinical immunology 20050201
Title: 2004 drug approval highlights: FDA update.
Journal: The Nurse practitioner 20050201
Title: Antibiotic activity of telithromycin and comparators against bacterial pathogens isolated from 3,043 patients with acute exacerbation of chronic bronchitis.
Journal: Annals of clinical microbiology and antimicrobials 20050101
Title: Pharmacodynamic analysis of the microbiological efficacy of telithromycin in patients with community-acquired pneumonia.
Journal: Clinical pharmacokinetics 20050101
Title: Effects of itraconazole or grapefruit juice on the pharmacokinetics of telithromycin.
Journal: Pharmacotherapy 20050101
Title: Telithromycin--a ketolide antibiotic for the treatment of outpatients with community-acquired respiratory tract infections.
Journal: Clinical nurse specialist CNS 20050101
Title: Efficacy and safety of telithromycin 800 mg once daily for 7 days in community-acquired pneumonia: an open-label, multicenter study.
Journal: BMC infectious diseases 20050101
Title: Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial.
Journal: Clinical pharmacokinetics 20050101
Title: Characterization of erythromycin-resistant Streptococcus pneumoniae in Korea, and In Vitro activity of telithromycin against erythromycin-resistant Streptococcus pneumoniae.
Journal: Microbial drug resistance (Larchmont, N.Y.) 20050101
Title: Pharmacodynamic activity of telithromycin against macrolide-susceptible and macrolide-resistant Streptococcus pneumoniae simulating clinically achievable free serum and epithelial lining fluid concentrations.
Journal: The Journal of antimicrobial chemotherapy 20041201
Title: Activity of telithromycin against erythromycin-susceptible and -resistant Streptococcus pneumoniae isolates from adults with invasive infections.
Journal: International journal of antimicrobial agents 20041201
Title: Introduction to PROTEkT: years 1-3 (1999-2002).
Journal: Journal of chemotherapy (Florence, Italy) 20041201
Title: PROTEKT years 1-3 (1999-2002): study design and methodology.
Journal: Journal of chemotherapy (Florence, Italy) 20041201
Title: Resistance trends in Streptococcus pneumoniae (PROTEKT years 1-3 [1999-2002]).
Journal: Journal of chemotherapy (Florence, Italy) 20041201
Title: Global distribution of Streptococcus pneumoniae serotypes isolated from paediatric patients during 1999-2000 and the in vitro efficacy of telithromycin and comparators.
Journal: Journal of medical microbiology 20041101
Title: [Pharmacoeconomic analysis of patients with acute exacerbation of chronic bronchitis treated with telithromycin or cefuroxime-axetil].
Journal: Revista clinica espanola 20041101
Title: Development of macrolide-resistance and comparative activity of telithromycin in streptococci in Austria, 1996-2002.
Journal: International journal of antimicrobial agents 20041001
Title: An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pyogenes and Streptococcus pneumoniae.
Journal: Current microbiology 20041001
Title: Telithromycin.
Journal: Expert review of anti-infective therapy 20041001
Title: [Molecular analytical evaluation of macrolide- and ketolide-resistant Streptococcus pneumoniae--mechanism of action of telithromycin and resistance to it].
Journal: The Japanese journal of antibiotics 20041001
Title: Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics.
Journal: Bioorganic & medicinal chemistry letters 20040906
Title: Potential interaction between telithromycin and warfarin.
Journal: The Annals of pharmacotherapy 20040901
Title: Macrolides and ketolides: azithromycin, clarithromycin, telithromycin.
Journal: Infectious disease clinics of North America 20040901
Title: Telithromycin (Ketek) for community-acquired respiratory tract infections.
Journal: The Nurse practitioner 20040901
Title: Efficacy and safety of oral telithromycin once daily for 5 days versus moxifloxacin once daily for 10 days in the treatment of acute bacterial rhinosinusitis.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20040901
Title: Telithromycin.
Journal: Nature reviews. Drug discovery 20040901
Title: New drugs.
Journal: Canadian family physician Medecin de famille canadien 20040901
Title: Telithromycin (Ketek) for respiratory infections.
Journal: The Medical letter on drugs and therapeutics 20040816
Title: Selection of resistance of telithromycin against Haemophilus influenzae, Moraxella catarrhalis and streptococci in comparison with macrolides.
Journal: The Journal of antimicrobial chemotherapy 20040801
Title: Activity of telithromycin against key pathogens associated with community-acquired respiratory tract infections.
Journal: The Journal of infection 20040801
Title: Telithromycin-induced acute interstitial nephritis: a first case report.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20040801
Title: Antibacterial susceptibility among Streptococcus pneumoniae isolated from paediatric and adult patients as part of the PROTEKT US study in 2001-2002.
Journal: The Journal of antimicrobial chemotherapy 20040801
Title: Clinical and bacteriological efficacy and safety of 5 and 7 day regimens of telithromycin once daily compared with a 10 day regimen of clarithromycin twice daily in patients with mild to moderate community-acquired pneumonia.
Journal: The Journal of antimicrobial chemotherapy 20040801
Title: Efficacy of telithromycin in community-acquired pneumonia caused by Legionella pneumophila.
Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20040801
Title: PROTEKT US: results from the second year of this longitudinal surveillance study of antimicrobial resistance among respiratory tract pathogens isolated from paediatric and adult patients in the USA. Introduction.
Journal: The Journal of antimicrobial chemotherapy 20040801
Title: Evaluation of 5-day therapy with telithromycin, a novel ketolide antibacterial, for the treatment of tonsillopharyngitis.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040701
Title: Hospitalization rates among patients with community-acquired pneumonia treated with telithromycin vs clarithromycin: results from two randomized, double-blind, clinical trials.
Journal: Current medical research and opinion 20040701
Title: Treatment of acute Chlamydia pneumoniae infection with telithromycin in C57BL/6J mice.
Journal: The Journal of antimicrobial chemotherapy 20040601
Title: Clinical efficacy of ketolides in the treatment of respiratory tract infections.
Journal: The Journal of antimicrobial chemotherapy 20040601
Title: Macrolide resistance phenotypes of commensal viridans group streptococci and Gemella spp. and PCR detection of resistance genes.
Journal: International journal of antimicrobial agents 20040601
Title: Antibacterial resistance of community-acquired respiratory tract pathogens recovered from patients in Germany and activity of the Ketolide Telithromycin: results from the PROTEKT surveillance study (1999-2000).
Journal: Chemotherapy 20040601
Title: In vitro activity of telithromycin, quinupristin/dalfopristin, linezolid and comparator antimicrobial agents against Staphylococcus aureus clinical isolates.
Journal: Journal of chemotherapy (Florence, Italy) 20040601
Title: Pneumococcal resistance to macrolides, lincosamides, ketolides, and streptogramin B agents: molecular mechanisms and resistance phenotypes.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040515
Title: Comparative in vitro activity of telithromycin against macrolide-resistant and -susceptible Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae.
Journal: The Journal of antimicrobial chemotherapy 20040501
Title: Comparative study of the in vitro activity of a new fluoroquinolone, ABT-492.
Journal: The Journal of antimicrobial chemotherapy 20040501
Title: Comparison of hospitalization rates in patients with community-acquired pneumonia treated with telithromycin for 5 or 7 days or clarithromycin for 10 days.
Journal: Current medical research and opinion 20040501
Title: Comparison of hospitalization rates in patients with community-acquired pneumonia treated with 10 days of telithromycin or clarithromycin.
Journal: Current medical research and opinion 20040501
Title: Comparison of the in vitro efficacy of telithromycin (HMR 3647) and levofloxacin with 22 antibiotic compounds against Bosea and Afipia species.
Journal: The Journal of antimicrobial chemotherapy 20040401
Title: Streptococcus pneumoniae and Streptococcus pyogenes isolated from a paediatric population in Great Britain and Ireland: the in vitro activity of telithromcycin versus comparators.
Journal: The Journal of infection 20040401
Title: Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against community-acquired bacterial respiratory tract pathogens in the United States: findings from the PROTEKT US study, 2000-2001.
Journal: Clinical therapeutics 20040401
Title: Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment.
Journal: Journal of clinical pharmacology 20040301
Title: [Telithromycin].
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20040301
Title: Efficacy of telithromycin in the treatment of experimental Bacteroides fragilis intraabdominal abscess in the senescent mice.
Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20040301
Title: Tissue kinetics of telithromycin, the first ketolide antibacterial.
Journal: The Journal of antimicrobial chemotherapy 20040201
Title: Clinical use of antimicrobial pharmacodynamic profiles to optimise treatment outcomes in community-acquired bacterial respiratory tract infections: application to telithromycin.
Journal: Expert opinion on pharmacotherapy 20040201
Title: Comparative activity of telithromycin against macrolide-resistant isolates of Streptococcus pneumoniae: results of two years of the PROTEKT surveillance study.
Journal: Journal of chemotherapy (Florence, Italy) 20040201
Title: [Telithromycin].
Journal: Klinicka mikrobiologie a infekcni lekarstvi 20040201
Title: Antibacterial resistance among children with community-acquired respiratory tract infections (PROTEKT 1999-2000).
Journal: The Journal of infection 20040101
Title: Clinical and bacteriological efficacy of the ketolide telithromycin against isolates of key respiratory pathogens: a pooled analysis of phase III studies.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040101
Title: [How effective are linezolid and telithromycin? The resistance situation of pathogenic gram positive infections in Germany].
Journal: Pharmazie in unserer Zeit 20040101
Title: [Two new antibiotics with special qualities: the pharmacokinetics of linezolid and telithromycin].
Journal: Pharmazie in unserer Zeit 20040101
Title: [Importance in respiratory tract infections. Ketolides: clinical aspects].
Journal: Pharmazie in unserer Zeit 20040101
Title: [Adverse effects of anti-infectives. Undesirable effects and interactions of ketolides and oxazolidonones].
Journal: Pharmazie in unserer Zeit 20040101
Title: Efficacy and tolerability of once-daily oral telithromycin compared with clarithromycin for the treatment of community-acquired pneumonia in adults.
Journal: Clinical therapeutics 20040101
Title: [Activity of telithromycin and other oral antibiotics against respiratory tract pathogens with acquired mechanisms of resistance].
Journal: Enfermedades infecciosas y microbiologia clinica 20040101
Title: Telithromycin.
Journal: Drugs 20040101
Title: Telithromycin: a brief review of a new ketolide antibiotic.
Journal: Journal of drugs in dermatology : JDD 20040101
Title: [Management of communal lower respiratory tract infections in the emergency ward: the role of Ketek (telithromycine)].
Journal: Medecine et maladies infectieuses 20040101
Title: Recently introduced antibiotics: a guide for the general physician.
Journal: Clinical medicine (London, England) 20040101
Title: Telithromycin and myasthenia gravis.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031201
Title: Optimizing outcomes with antimicrobial therapy through pharmacodynamic profiling.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201
Title: Penetration of oral telithromycin into female genital tissues.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201
Title: [Evaluation of ketoride antibiotics, telithromycin in treatment of respiratory tract infections (discussion)].
Journal: The Japanese journal of antibiotics 20031201
Title: Telithromycin post-antibiotic and post-antibiotic sub-MIC effects for 10 Gram-positive cocci.
Journal: The Journal of antimicrobial chemotherapy 20031101
Title: In vitro activity of newer antibiotics against Corynebacterium jeikeium, Corynebacterium amycolatum and Corynebacterium urealyticum.
Journal: International journal of antimicrobial agents 20031101
Title: In vitro activity of telithromycin compared with macrolides and fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis.
Journal: International journal of antimicrobial agents 20031101
Title: Ketolides: an emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae.
Journal: Expert opinion on emerging drugs 20031101
Title: Inhibitory action of telithromycin against Shiga toxin and endotoxin.
Journal: Biochemical and biophysical research communications 20031031
Title: Induction of telithromycin resistance in Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20031001
Title: A pooled analysis of telithromycin in the treatment of community-acquired respiratory tract infections in adults.
Journal: Infection 20031001
Title: [Digitalis -- poisoning, myopathy, ergotism.... When antibiotic and associated therapy become dangerous mixture].
Journal: MMW Fortschritte der Medizin 20030925
Title: Comparative activity of telithromycin against typical community-acquired respiratory pathogens.
Journal: The Journal of antimicrobial chemotherapy 20030901
Title: High-level telithromycin resistance in laboratory-generated mutants of Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20030901
Title: Ketolides: a new class of antibacterial agents for treatment of community-acquired respiratory tract infections in a primary care setting.
Journal: Mayo Clinic proceedings 20030901
Title: In vitro activities of new ketolide, telithromycin, and eight other macrolide antibiotics against Streptococcus pneumoniae having mefA and ermB genes that mediate macrolide resistance.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030901
Title: [The 3 molecules of the year].
Journal: Revue medicale de Bruxelles 20030901
Title: [Pharmacoeconomic analysis of community-acquired pneumonia treatment with telithromycin or clarithromycin].
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20030901
Title: Pharmacokinetics of the ketolide telithromycin after single and repeated doses in patients with hepatic impairment.
Journal: International journal of antimicrobial agents 20030801
Title: Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against bacterial pathogens from community-acquired respiratory tract infections: data from the first year of PROTEKT (1999-2000).
Journal: Journal of chemotherapy (Florence, Italy) 20030801
Title: Interaction of macrolides and ketolides with the phagocytic cell line PLB-985.
Journal: Journal of chemotherapy (Florence, Italy) 20030801
Title: Efficacy and tolerability of telithromycin for 5 or 10 days vs amoxicillin/clavulanic acid for 10 days in acute maxillary sinusitis.
Journal: Ear, nose, & throat journal 20030801
Title: Streptococcus pyogenes isolates with characterized macrolide resistance mechanisms in Spain: in vitro activities of telithromycin and cethromycin.
Journal: The Journal of antimicrobial chemotherapy 20030701
Title: Selection of ketolide resistance in Staphylococcus aureus.
Journal: International journal of antimicrobial agents 20030701
Title: Activity of telithromycin and seven other agents against 1034 pediatric Streptococcus pneumoniae isolates from ten central and eastern European centers.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701
Title: Telithromycin 800 mg once daily for seven to ten days is an effective and well-tolerated treatment for community-acquired pneumonia.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701
Title: In vitro activity of telithromycin (HMR 3647) against Greek Streptococcus pyogenes and Streptococcus pneumoniae clinical isolates with different macrolide susceptibilities.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701
Title: Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701
Title: [Telithromycin in the management of lower respiratory tract infections in the hospital].
Journal: Presse medicale (Paris, France : 1983) 20030607
Title: Telithromycin in the treatment of community-acquired pneumonia: a pooled analysis.
Journal: Respiratory medicine 20030601
Title: Efficacy and tolerability of once-daily oral therapy with telithromycin compared with trovafloxacin for the treatment of community-acquired pneumonia in adults.
Journal: International journal of clinical practice 20030601
Title: [Telithromycin in daily practice in admission services and treatment of emergencies].
Journal: Presse medicale (Paris, France : 1983) 20030531
Title: In vitro and in vivo antibacterial activities of telithromycin.
Journal: Chemotherapy 20030501
Title: Telithromycin (HMR 3647) achieves high and sustained concentrations in tonsils of patients undergoing tonsillectomy.
Journal: International journal of antimicrobial agents 20030501
Title: Community-acquired respiratory tract infections caused by resistant pneumococci: clinical and bacteriological efficacy of the ketolide telithromycin.
Journal: The Journal of antimicrobial chemotherapy 20030401
Title: [Macrolides, ketolides and streptogramins].
Journal: Enfermedades infecciosas y microbiologia clinica 20030401
Title: Drugs of the 21st century: telithromycin (HMR 3647)--the first ketolide.
Journal: The Journal of antimicrobial chemotherapy 20030301
Title: Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects.
Journal: Clinical pharmacology and therapeutics 20030301
Title: [New antibiotics in primary care].
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20030301
Title: [Resistance of respiratory tract infection agents is still increasing. Is its time for new antibiotic strategies?].
Journal: MMW Fortschritte der Medizin 20030227
Title: Preferential inhibition of protein synthesis by ketolide antibiotics in Haemophilus influenzae cells.
Journal: Current microbiology 20030201
Title: [Telithromycin, first ketolide].
Journal: Revue medicale de Bruxelles 20030201
Title: Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: a multicenter, randomized, double-blind, parallel-group study.
Journal: Clinical therapeutics 20030201
Title: Dead bugs don't mutate: susceptibility issues in the emergence of bacterial resistance.
Journal: Emerging infectious diseases 20030101
Title: Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20030101
Title: [Telithromycin and exacerbation in myasthenia gravis].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101
Title: Relief of symptoms in patients with group A beta-hemolytic streptococcus tonsillopharyngitis: comparison between telithromycin and penicillin V.
Journal: Scandinavian journal of infectious diseases 20030101
Title: Oral telithromycin 800 mg once daily for 5 days versus cefuroxime axetil 500 mg twice daily for 10 days in adults with acute exacerbations of chronic bronchitis.
Journal: The Journal of international medical research 20030101
Title: Telithromycin: the first ketolide antibacterial for the treatment of community-acquired respiratory tract infections.
Journal: International journal of clinical practice 20030101
Title: A comparison of the efficacy of telithromycin versus cefuroxime axetil in the treatment of acute bacterial maxillary sinusitis.
Journal: American journal of rhinology 20030101
Title: [Telithromycin, first ketolide to diversify the management of community-acquired respiratory tract infections. Importance in emergency care].
Journal: Presse medicale (Paris, France : 1983) 20021221
Title: Comparison of the antibacterial activities of ampicillin, ciprofloxacin, clarithromycin, telithromycin and quinupristin/dalfopristin against intracellular non-typeable Haemophilus influenzae.
Journal: The Journal of antimicrobial chemotherapy 20021201
Title: In vitro activity of quinupristin/dalfopristin, linezolid, telithromycin and comparator antimicrobial agents against 13 species of coagulase-negative staphylococci.
Journal: The Journal of antimicrobial chemotherapy 20021201
Title: Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers.
Journal: Chemotherapy 20021201
Title: Efficacy and tolerability of once-daily telithromycin compared with high-dose amoxicillin for treatment of community-acquired pneumonia.
Journal: Infection 20021201
Title: Telithromycin inhibition of protein synthesis and 50S ribosomal subunit formation in Streptococcus pneumoniae cells.
Journal: Current microbiology 20021101
Title: Telithromycin is as effective as amoxicillin/clavulanate in acute exacerbations of chronic bronchitis.
Journal: Respiratory medicine 20021101
Title: [Efficacy trial in general practice substantiated. New antibiotic with strong effectiveness and tolerance].
Journal: MMW Fortschritte der Medizin 20021017
Title: Ketolides: the future of the macrolides?
Journal: Current opinion in pharmacology 20021001
Title: Comparative in vitro activity of penicillin G, levofloxacin, moxifloxacin, telithromycin, pristinamycin, quinupristin-dalfopristin and linezolid against ofloxacin-intermediate and -resistant Streptococcus pneumoniae.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20021001
Title: The ketolide antibiotic ABT-773 is a specific inhibitor of translation and 50S ribosomal subunit formation in Streptococcus pneumoniae cells.
Journal: Current microbiology 20020901
Title: Genotypic characterization of macrolide-resistant strains of Streptococcus pneumoniae isolated in Quebec, Canada, and in vitro activity of ABT-773 and telithromycin.
Journal: The Journal of antimicrobial chemotherapy 20020901
Title: Prevalence of macrolide and tetracycline resistance mechanisms in Streptococcus pyogenes isolates and in vitro susceptibility to telithromycin.
Journal: The Journal of antimicrobial chemotherapy 20020901
Title: Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and compatative in vitro activity of the ketolide, telithromycin.
Journal: The Journal of antimicrobial chemotherapy 20020901
Title: Comparison of telithromycin, a new ketolide, with erythromycin and clarithromycin for the treatment of Haemophilus influenzae pneumonia in suckling, middle aged and senescent mice.
Journal: International journal of antimicrobial agents 20020901
Title: From macrolides to ketolides: What is available for the treatment of outpatient respiratory tract infections?
Journal: Postgraduate medicine 20020901
Title: In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis.
Journal: The Journal of antimicrobial chemotherapy 20020701
Title: In vitro activity of linezolid, synercid and telithromycin against genetically defined high level fluoroquinolone-resistant methicillin-resistant Staphylococcus aureus.
Journal: International journal of antimicrobial agents 20020701
Title: [Are ketolides replacing macrolides in chronic bronchitis?].
Journal: Der Internist 20020701
Title: Introduction: PROTEKT against respiratory tract infection.
Journal: Journal of chemotherapy (Florence, Italy) 20020701
Title: Global surveillance through PROTEKT: the first year.
Journal: Journal of chemotherapy (Florence, Italy) 20020701
Title: What can PROTEKT tell us at a local level?
Journal: Journal of chemotherapy (Florence, Italy) 20020701
Title: Prevalence and characterization of macrolide resistance in clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes from North America.
Journal: Journal of chemotherapy (Florence, Italy) 20020701
Title: The rise of fluoroquinolone resistance: fact or fiction.
Journal: Journal of chemotherapy (Florence, Italy) 20020701
Title: Penetration of telithromycin (HMR 3647), a new ketolide antimicrobial, into inflammatory blister fluid following oral administration.
Journal: The Journal of antimicrobial chemotherapy 20020601
Title: Efficacy and tolerability of once-daily therapy with telithromycin for 5 or 10 days for the treatment of acute maxillary sinusitis.
Journal: Chemotherapy 20020501
Title: Molecular characterization of ketolide-resistant erm(A)-carrying Staphylococcus aureus isolates selected in vitro by telithromycin, ABT-773, quinupristin and clindamycin.
Journal: The Journal of antimicrobial chemotherapy 20020401
Title: Osmolytes stimulate the reconstitution of functional 50S ribosomes from in vitro transcripts of Escherichia coli 23S rRNA.
Journal: RNA (New York, N.Y.) 20020401
Title: In vitro activity of new ketolides against macrolide-susceptible and -resistant Staphylococcus aureus isolates with defined resistance gene status.
Journal: The Journal of antimicrobial chemotherapy 20020301
Title: Telithromycin: the first of the ketolides.
Journal: The Annals of pharmacotherapy 20020301
Title: [Bacterial airway infections. Standard antibiotics more often ineffective].
Journal: MMW Fortschritte der Medizin 20020221
Title: In vitro activity of telithromycin against Streptococcus pneumoniae resistant to other antibiotics, including cefotaxime.
Journal: The Journal of antimicrobial chemotherapy 20020201
Title: [in vitro activity of telithromycin against Haemophilus influenzae].
Journal: Pathologie-biologie 20020201
Title: Will resistance to ketolides develop in Streptococcus pneumoniae?
Journal: The Journal of infection 20020201
Title: Pharmacodynamic rationale for short-duration antibacterial therapy.
Journal: The Journal of infection 20020201
Title: Clinical efficacy of new antibacterial therapies in at-risk populations.
Journal: The Journal of infection 20020201
Title: Evolving resistance patterns in community-acquired respiratory tract pathogens: first results from the PROTEKT global surveillance study. Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin.
Journal: The Journal of infection 20020201
Title: Detection of transposon Tn5432-mediated macrolide-lincosamide-streptogramin B (MLSB) resistance in cutaneous propionibacteria from six European cities.
Journal: The Journal of antimicrobial chemotherapy 20020101
Title: Molecular analysis of constitutively expressed erm(C) genes selected in vitro by incubation in the presence of the noninducers quinupristin, telithromycin, or ABT-773.
Journal: Microbial drug resistance (Larchmont, N.Y.) 20020101
Title: Efficacy and safety of telithromycin in community-acquired pneumonia.
Journal: Current medical research and opinion 20020101
Title: Lack of effect of food on the bioavailability of a new ketolide antibacterial, telithromycin.
Journal: Scandinavian journal of infectious diseases 20020101
Title: [Telithromycin: a new therapeutic option for community-acquired respiratory infection].
Journal: Revista de medicina de la Universidad de Navarra 20020101
Title: Recent developments on ketolides and macrolides.
Journal: Current medicinal chemistry 20011201
Title: In vitro activity of ABT-773, telithromycin and eight other antimicrobials against erythromycin-resistant Streptococcus pneumoniae respiratory isolates of children.
Journal: International journal of antimicrobial agents 20011201
Title: Predicting antibacterial response from pharmacodynamic and pharmacokinetic profiles.
Journal: Infection 20011201
Title: Clinical management of respiratory tract infections in the community: experience with telithromycin.
Journal: Infection 20011201
Title: Activity of telithromycin against 26 quinolone-resistant pneumococci with known quinolone-resistance mechanisms.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20011201
Title: Telithromycin. Aventis Pharma.
Journal: Current opinion in investigational drugs (London, England : 2000) 20011201
Title: Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens.
Journal: Journal of medicinal chemistry 20011122
Title: Effect of pH on the susceptibility of Helicobacter pylori to the ketolide telithromycin (HMR 3647) and clarithromycin.
Journal: The Journal of antimicrobial chemotherapy 20011101
Title: [A new antibiotic against respiratory tract infections. More power against pneumococci].
Journal: MMW Fortschritte der Medizin 20011101
Title: Telithromycin: an oral ketolide for respiratory infections.
Journal: Pharmacotherapy 20011001
Title: [Ketolide antibiotics. A new therapeutic option in respiratory tract infections].
Journal: MMW Fortschritte der Medizin 20010906
Title: In vitro activity of telithromycin, a new ketolide, against Chlamydia pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20010901
Title: Overcoming antimicrobial resistance: profile of a new ketolide antibacterial, telithromycin.
Journal: The Journal of antimicrobial chemotherapy 20010901
Title: Activity of telithromycin, a new ketolide antibacterial, against atypical and intracellular respiratory tract pathogens.
Journal: The Journal of antimicrobial chemotherapy 20010901
Title: Activity of the ketolide antibacterial telithromycin against typical community-acquired respiratory pathogens.
Journal: The Journal of antimicrobial chemotherapy 20010901
Title: [Multicenter study in southern South America of the in vitro activity of telithromycin in strains with defined resistance phenotypes isolated from community-acquired respiratory infections].
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20010901
Title: Telithromycin is active against Mycobacterium avium in mice despite lacking significant activity in standard in vitro and macrophage assays and is associated with low frequency of resistance during treatment.
Journal: Antimicrobial agents and chemotherapy 20010801
Title: The emerging new generation of antibiotic: ketolides.
Journal: Current drug targets. Infectious disorders 20010801
Title: Interpretative criteria and quality control parameters for telithromycin disc diffusion susceptibility tests.
Journal: The Journal of antimicrobial chemotherapy 20010701
Title: Activity of the ketolide telithromycin (HMR-3647) against erythromycin-susceptible and -resistant pneumococci isolated in the UK.
Journal: International journal of antimicrobial agents 20010701
Title: Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of gram-positive cocci.
Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010701
Title: FDA committee gives new antibiotic mixed endorsement.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010615
Title: Lung concentrations of telithromycin after oral dosing.
Journal: The Journal of antimicrobial chemotherapy 20010601
Title: Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus influenzae.
Journal: International journal of antimicrobial agents 20010601
Title: Bacterial ribosomal subunit synthesis: a novel antibiotic target.
Journal: Current drug targets. Infectious disorders 20010501
Title: In vitro activity of telithromycin (HMR 3647) against 502 strains of anaerobic bacteria.
Journal: The Journal of antimicrobial chemotherapy 20010401
Title: Antibacterial activity of telithromycin (HMR 3647) in relation to in vitro simulated human plasma kinetics.
Journal: The Journal of antimicrobial chemotherapy 20010401
Title: Telithromycin: a new ketolide antimicrobial for treatment of respiratory tract infections.
Journal: Expert opinion on investigational drugs 20010201
Title: Uptake and intracellular activity of ketolide HMR 3647 in human phagocytic and non-phagocytic cells.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010201
Title: Bacteroides fragilis-induced intra-abdominal abscess in an experimental model treated with telithromycin (HMR 3647).
Journal: Chemotherapy 20010101
Title: In vitro activity of ketolides HMR 3004 and HMR 3647 and seven other antimicrobial agents against Corynebacterium diphtheriae.
Journal: The Journal of antimicrobial chemotherapy 20010101
Title: HMR 3647 human-like treatment of experimental pneumonia due to penicillin-resistant and erythromycin-resistant Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20010101
Title: Telithromycin.
Journal: Drugs 20010101
Title: Inhibitory and bactericidal effects of telithromycin (HMR 3647, RU 56647) and five comparative antibiotics, used singly and in combination, against vancomycin-resistant and vancomycin-susceptible enterococci.
Journal: Chemotherapy 20010101
Title: Macrolide resistance in Streptococcus pyogenes isolates from throat infections in the region of Aachen, Germany.
Journal: Microbial drug resistance (Larchmont, N.Y.) 20010101
Title: Structure-activity relationships of ketolides vs. macrolides.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010101
Title: Safeguarding future antimicrobial options: strategies to minimize resistance.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010101
Title: Microbiological profile of telithromycin, the first ketolide antimicrobial.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010101
Title: Pharmacodynamic and pharmacokinetic considerations in antimicrobial selection: focus on telithromycin.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010101
Title: Community-acquired pneumonia: the evolving challenge.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010101
Title: [Ribosomal antibiotics].
Journal: Molekuliarnaia biologiia 20010101
Title: Efficacy of short-course therapy with the ketolide telithromycin compared with 10 days of penicillin V for the treatment of pharyngitis/tonsillitis.
Journal: Scandinavian journal of infectious diseases 20010101
Title: In vitro activity of the new ketolide telithromycin and other antibiotics against Streptococcus pneumoniae in Belgium.
Journal: Acta clinica Belgica 20010101
Title: In vitro activities of the ketolides telithromycin (HMR 3647) and HMR 3004 compared to those of clarithromycin against slowly growing mycobacteria at pHs 6.8 and 7.4.
Journal: Antimicrobial agents and chemotherapy 20001001
Title: In vitro susceptibilities of rapidly growing mycobacteria to telithromycin (HMR 3647) and seven other antimicrobials.
Journal: Antimicrobial agents and chemotherapy 20000101
Title: Use of ketolides in combination with other drugs to treat experimental toxoplasmosis.
Journal: The Journal of antimicrobial chemotherapy 19981101
Title: The ketolide antibiotics HMR 3647 and HMR 3004 are active against Toxoplasma gondii in vitro and in murine models of infection.
Journal: Antimicrobial agents and chemotherapy 19971001
