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192185-71-0,MFCD09837802
Catalog No.:AA00ABMH

192185-71-0 | Tipifarnib S-Enantiomer

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$73.00   $51.00
- +
5mg
≥98%
in stock  
$309.00   $216.00
- +
10mg
≥98%
in stock  
$506.00   $354.00
- +
25mg
≥98%
in stock  
$722.00   $505.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABMH
Chemical Name:
Tipifarnib S-Enantiomer
CAS Number:
192185-71-0
Molecular Formula:
C27H22Cl2N4O
Molecular Weight:
489.3958
MDL Number:
MFCD09837802
SMILES:
Clc1ccc(cc1)[C@@](c1cncn1C)(c1ccc2c(c1)c(cc(=O)n2C)c1cccc(c1)Cl)N
Properties
Computed Properties
 
Complexity:
785  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
4.1  

Literature

Title: Toward the development of innovative bifunctional agents to induce differentiation and to promote apoptosis in leukemia: clinical candidates and perspectives.

Journal: Journal of medicinal chemistry 20101014

Title: Rational modification of a candidate cancer drug for use against Chagas disease.

Journal: Journal of medicinal chemistry 20090326

Title: Impact on farnesyltransferase inhibition of 4-chlorophenyl moiety replacement in the Zarnestra series.

Journal: European journal of medicinal chemistry 20070501

Title: Kraus JM, et al. Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem. 2009 Mar 26;52(6):1639-47.

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SDS
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