Name: Name:Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-, (2Z)-2-butenedioate (1:1)
Brand: AABLOCKS
SKU: AA002FOX
Rating: 90 (10 reviews)

Catalog No.: AA002FOX

192231-16-6 | Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-, (2Z)-2-butenedioate (1:1)

Pack Size： 5mg

Purity： ≥98%(HPLC)

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$297.00 $208.00

Pack Size： 10mg

Purity： ≥98%(HPLC)

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$427.00 $299.00

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Technical Information

Catalog Number: AA002FOX

Chemical Name: Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-, (2Z)-2-butenedioate (1:1)

CAS Number: 192231-16-6

Molecular Formula: C16H18N2O4

Molecular Weight: 302.3251

MDL Number: MFCD00952087

SMILES: OC(=O)/C=C\C(=O)O.C#Cc1cncc(c1)[C@@H]1CCCN1C

Properties

Complexity: 359

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 22

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Literature fold

Title: Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.

Journal: The Journal of organic chemistry20110805

Title: Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist.

Journal: Brain research20081009

Title: Expedient five-step synthesis of SIB-1508Y from natural nicotine.

Journal: The Journal of organic chemistry20061027

Title: Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease.

Journal: Neurology20060214

Title: Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20030501

Title: Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine.

Journal: The Journal of pharmacology and experimental therapeutics20000901