Title: Crystal structure of human cytochrome P450 2D6 with prinomastat bound.
Journal: The Journal of biological chemistry 20120330
Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal: Journal of medicinal chemistry 20110714
Title: A high throughput screen identifies chemical modulators of the laminin-induced clustering of dystroglycan and aquaporin-4 in primary astrocytes.
Journal: PloS one 20110101
Title: Hydroxamates: relationships between structure and plasma stability.
Journal: Journal of medicinal chemistry 20091112
Title: Inhibition of gelatinase activity reduces neural injury in an ex vivo model of hypoxia-ischemia.
Journal: Neuroscience 20090602
Title: Current perspective of TACE inhibitors: a review.
Journal: Bioorganic & medicinal chemistry 20090115
Title: Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat.
Journal: Journal of neuroinflammation 20080101
Title: Specific inhibition of autoimmune T cell transmigration contributes to beta cell functionality and insulin synthesis in non-obese diabetic (NOD) mice.
Journal: The Journal of biological chemistry 20071102
Title: Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators.
Journal: Toxicon : official journal of the International Society on Toxinology 20070401
Title: Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases.
Journal: Bioorganic & medicinal chemistry 20070315
Title: Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.
Journal: Investigative ophthalmology & visual science 20070201
Title: Rapid vascular regrowth in tumors after reversal of VEGF inhibition.
Journal: The Journal of clinical investigation 20061002
Title: Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides.
Journal: Bioorganic & medicinal chemistry 20060615
Title: Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050901
Title: Phase III study of matrix metalloproteinase inhibitor prinomastat in non-small-cell lung cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050201
Title: Protease inhibitors in the clinic.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20050101
Title: Cartilage degradation independent of MMP/aggrecanases.
Journal: Osteoarthritis and cartilage 20041201
Title: The effect of prinomastat (AG3340), a potent inhibitor of matrix metalloproteinase, on a new animal model of epiretinal membrane.
Journal: Retina (Philadelphia, Pa.) 20041001
Title: Preventive versus treatment effect of AG3340, a potent matrix metalloproteinase inhibitor in a rat model of choroidal neovascularization.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040601
Title: Receptor flexibility in the in silico screening of reagents in the S1' pocket of human collagenase.
Journal: Journal of medicinal chemistry 20040520
Title: The matrix metalloproteinase inhibitor prinomastat enhances photodynamic therapy responsiveness in a mouse tumor model.
Journal: Cancer research 20040401
Title: Evaluation of P1'-diversified phosphinic peptides leads to the development of highly selective inhibitors of MMP-11.
Journal: Journal of medicinal chemistry 20040115
Title: Stereospecific synthesis of 5-substituted 2-bisarylthiocyclopentane carboxylic acids as specific matrix metalloproteinase inhibitors.
Journal: Journal of medicinal chemistry 20030828
Title: Prinomastat, a hydroxamate inhibitor of matrix metalloproteinases, has a complex effect on migration of breast carcinoma cells.
Journal: International journal of cancer 20030501
Title: Mechanical stretch induces MMP-2 release and activation in lung endothelium: role of EMMPRIN.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030301
Title: [Matrix metalloproteinases and atherosclerosis. Therapeutic aspects].
Journal: Annales de biologie clinique 20030101
Title: Protease inhibitors: synthesis of matrix metalloproteinase and bacterial collagenase inhibitors incorporating 5-amino-2-mercapto-1,3,4-thiadiazole zinc binding functions.
Journal: Bioorganic & medicinal chemistry letters 20021007
Title: Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase.
Journal: The Journal of biological chemistry 20020322
Title: Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.
Journal: Journal of medicinal chemistry 20020103
Title: Efficacy of Prinomastat) (AG3340), a matrix metalloprotease inhibitor, in treatment of retinal neovascularization.
Journal: Current eye research 20020101
Title: Imaging metalloproteinase activity in vivo.
Journal: Nature medicine 20010601
Title: Evaluation of intraocular pharmacokinetics and toxicity of prinomastat (AG3340) in the rabbit.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601
Title: Development of matrix metalloproteinase inhibitors in cancer therapy.
Journal: Journal of the National Cancer Institute 20010207
Title: HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors.
Journal: Annals of neurology 20010201
Title: The effect of prinomastat (AG3340), a synthetic inhibitor of matrix metalloproteinases, on posttraumatic proliferative vitreoretinopathy.
Journal: Ophthalmic research 20010101
Title: Therapeutic angiogenesis inhibitors in the treatment of cancer.
Journal: Advances in internal medicine 20010101
Title: Prinomastat, a hydroxamate-based matrix metalloproteinase inhibitor. A novel pharmacological approach for tissue remodelling-related diseases.
Journal: Expert opinion on investigational drugs 20000901
Title: Protease inhibitors: current status and future prospects.
Journal: Journal of medicinal chemistry 20000210
Title: Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials.
Journal: Annals of the New York Academy of Sciences 19990630
