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Title: Determination of bupropion and its main metabolite in rat plasma by LC-MS and its application to pharmacokinetics.
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Title: A major metabolite of bupropion reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets.
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Title: A simple and sensitive LC-ESI-MS (ion trap) method for the determination of bupropion and its major metabolite, hydroxybupropion in rat plasma and brain microdialysates.
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Title: Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine.
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Title: Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin.
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Title: The in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19.
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Title: Effects of woohwangcheongsimwon suspension on the pharmacokinetics of bupropion and its active metabolite, 4-hydroxybupropion, in healthy subjects.
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Title: Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation.
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Title: Use of enantiomeric bupropion and hydroxybupropion to assess CYP2B6 activity in glomerular kidney diseases.
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Title: Ultra-performance liquid chromatography- tandem mass spectrometry method for the determination of bupropion and its main metabolites in human whole blood.
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Title: Effect of St. John's wort supplementation on the pharmacokinetics of bupropion in healthy male Chinese volunteers.
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Title: Effects of Ginkgo biloba extract on the pharmacokinetics of bupropion in healthy volunteers.
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Title: In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes.
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Title: Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation.
Journal: European journal of clinical pharmacology 20090401
Title: Transdermal delivery of bupropion and its active metabolite, hydroxybupropion: a prodrug strategy as an alternative approach.
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Title: Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects.
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Title: Stereoselective metabolism of bupropion by cytochrome P4502B6 (CYP2B6) and human liver microsomes.
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Title: Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir.
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Title: In vivo evaluation of a transdermal codrug of 6-beta-naltrexol linked to hydroxybupropion in hairless guinea pigs.
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Title: Prasugrel, a new thienopyridine antiplatelet drug, weakly inhibits cytochrome P450 2B6 in humans.
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Title: Effect of commonly used organic solvents on the kinetics of cytochrome P450 2B6- and 2C8-dependent activity in human liver microsomes.
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Title: Stereoselective analysis of bupropion and hydroxybupropion in human plasma and urine by LC/MS/MS.
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Title: Stereoselective analysis of hydroxybupropion and application to drug interaction studies.
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Title: Lopinavir/ritonavir reduces bupropion plasma concentrations in healthy subjects.
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Title: Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6.
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Title: Synthesis and hydrolytic behavior of two novel tripartate codrugs of naltrexone and 6beta-naltrexol with hydroxybupropion as potential alcohol abuse and smoking cessation agents.
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Title: Enhancement of transdermal delivery of 6-beta-naltrexol via a codrug linked to hydroxybupropion.
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Title: Ritonavir has minimal impact on the pharmacokinetic disposition of a single dose of bupropion administered to human volunteers.
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Title: Obesity drugs in clinical development.
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Title: HPLC assay for bupropion and its major metabolites in human plasma.
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Title: The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects.
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Title: Pharmacokinetics of bupropion and its metabolites in haemodialysis patients who smoke. A single dose study.
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