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19254-69-4,MFCD17167010
Catalog No.:AA002G0B

19254-69-4 | Ergosta-4,6,8(14),22-tetraen-3-one

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5mg
2 weeks  
$878.00   $615.00
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20mg
≥98%
2 weeks  
$2,098.00   $1,469.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA002G0B
Chemical Name:
Ergosta-4,6,8(14),22-tetraen-3-one
CAS Number:
19254-69-4
Molecular Formula:
C28H40O
Molecular Weight:
392.6166
MDL Number:
MFCD17167010
SMILES:
CC([C@H](/C=C/[C@H]([C@H]1CCC2=C3[C@H](CC[C@]12C)[C@@]1(C)CCC(=O)C=C1C=C3)C)C)C
Properties
Computed Properties
 
Complexity:
806  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
6.8  

Literature

Title: Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Journal: Chemico-biological interactions 20170801

Title: Effect of ergosta-4,6,8(14),22-tetraen-3-one (ergone) on adenine-induced chronic renal failure rat: a serum metabonomic study based on ultra performance liquid chromatography/high-sensitivity mass spectrometry coupled with MassLynx i-FIT algorithm.

Journal: Clinica chimica acta; international journal of clinical chemistry 20121009

Title: Ultra performance liquid chromatography coupled with electrospray and atmospheric pressure chemical ionization (ESCi)-quadrupole time-of-flight mass spectrometry with novel mass spectrometry(Elevated Energy) (MS(E)) data collection technique: determination and pharmacokinetics, tissue distribution and biliary excretion study of ergone in rat.

Journal: Journal of separation science 20120701

Title: Solvent effect on the absorption and fluorescence of ergone: determination of ground and excited state dipole moments.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

Title: Ergosta-4,6,8(14),22-tetraen-3-one isolated from Polyporus umbellatus prevents early renal injury in aristolochic acid-induced nephropathy rats.

Journal: The Journal of pharmacy and pharmacology 20111201

Title: Ergosta-4,6,8(14),22-tetraen-3-one induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Journal: Biochimica et biophysica acta 20110401

Title: Quantitative HPLC method and pharmacokinetic studies of ergosta-4,6,8(14),22-tetraen-3-one, a natural product with diuretic activity from Polyporus umbellatus.

Journal: Biomedical chromatography : BMC 20101001

Title: Rapid resolution liquid chromatography-mass spectrometry and high-performance liquid chromatography-fluorescence detection for metabolism and pharmacokinetic studies of ergosta-4,6,8(14),22-tetraen-3-one.

Journal: Analytica chimica acta 20100824

Title: Pecipamide, a new sphingosine derivative from the cultures of Polyporus picipes (Basidiomycetes).

Journal: Lipids 20100501

Title: A fast and sensitive HPLC-MS/MS analysis and preliminary pharmacokinetic characterization of ergone in rats.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100101

Title: Bioactivity-directed isolation, identification of diuretic compounds from Polyporus umbellatus.

Journal: Journal of ethnopharmacology 20091029

Title: Qualitative and quantitative analysis of the diuretic component ergone in Polyporus umbellatus by HPLC with fluorescence detection and HPLC-APCI-MS/MS.

Journal: Die Pharmazie 20090601

Title: Endophytic fungi found in association with Smallanthus sonchifolius (Asteraceae) as resourceful producers of cytotoxic bioactive natural products.

Journal: Journal of basic microbiology 20090401

Title: (22E)-Ergosta-6,22-diene-3beta,5alpha,8alpha-triol: a new polyhydroxysterol isolated from Lentinus edodes (Shiitake).

Journal: Natural product research 20090101

Title: Ergosta-4,6,8(14),22-tetraen-3-one from Vietnamese Xylaria sp. possessing inhibitory activity of nitric oxide production.

Journal: Natural product research 20080101

Title: [Studies on chemical constituents in the mycelia from fermented culture of Flammulina velutipes].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050201

Title: An anti-aldosteronic diuretic component (drain dampness) in Polyporus sclerotium.

Journal: Biological & pharmaceutical bulletin 20040601

Title: [Studies on the marker compounds for standardization of traditional Chinese medicine 'polyporus sclerotium ([symbol: see text])'].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030201

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