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Home Other Building Blocks 193746-75-7
193746-75-7,MFCD08690575
Catalog No.:AA00ABIU

193746-75-7 | SB242235

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$31.00   $22.00
- +
5mg
98%
in stock  
$75.00   $53.00
- +
10mg
98%
in stock  
$112.00   $78.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABIU
Chemical Name:
SB242235
CAS Number:
193746-75-7
Molecular Formula:
C19H20FN5O
Molecular Weight:
353.3934
MDL Number:
MFCD08690575
SMILES:
COc1nccc(n1)c1n(cnc1c1ccc(cc1)F)C1CCNCC1
Properties
Computed Properties
 
Complexity:
442  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.1  

Literature

Title: Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes.

Journal: Bioorganic & medicinal chemistry letters 20080801

Title: Species and response dependent differences in the effects of MAPK inhibitors on P2X(7) receptor function.

Journal: British journal of pharmacology 20061201

Title: Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice.

Journal: The Journal of investigative dermatology 20050601

Title: Benzimidazolone p38 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20040223

Title: Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542.

Journal: Molecular pharmacology 20020701

Title: Pyrimidinylimidazole inhibitors of p38: cyclic N-1 imidazole substituents enhance p38 kinase inhibition and oral activity.

Journal: Bioorganic & medicinal chemistry letters 20011105

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SDS
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Tags:193746-75-7 Molecular Formula|193746-75-7 MDL|193746-75-7 SMILES|193746-75-7 SB242235