[1]Patent:WO2012/70066,2012,A1,.Locationinpatent:Page/Pagecolumn4
[1]Patent:US2013/237700,2013,A1,.Locationinpatent:Paragraph0028
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[1]Patent:US2008/27043,2008,A1.Locationinpatent:Page/Pagecolumn4
[1]Patent:WO2012/70066,2012,A1.Locationinpatent:Page/Pagecolumn4
Title: Taurolidine: mode of administration in mouse tumor models.
Journal: International journal of cancer 20121201
Title: Significant reduction in central venous catheter-related bloodstream infections in children on HPN after starting treatment with taurolidine line lock.
Journal: Journal of pediatric gastroenterology and nutrition 20121001
Title: Biofilm formation in long-term central venous catheters in children with cancer: a randomized controlled open-labelled trial of taurolidine versus heparin.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20121001
Title: Taurolidine: Mode of administration in mouse tumor models.
Journal: International journal of cancer 20120915
Title: The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity.
Journal: International journal of cancer 20120901
Title: Taurolidine lock solution in the secondary prevention of central venous catheter-associated bloodstream infection in home parenteral nutrition patients.
Journal: Clinical nutrition (Edinburgh, Scotland) 20120801
Title: TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cells.
Journal: Anticancer research 20120701
Title: Efficacy of taurolidine against periodontopathic species--an in vitro study.
Journal: Clinical oral investigations 20120601
Title: Taxol and taurine protect the renal tissue of rats after unilateral ureteral obstruction: a stereological survey.
Journal: Korean journal of urology 20120501
Title: Antibacterial effect of taurolidine (2%) on established dental plaque biofilm.
Journal: Clinical oral investigations 20120401
Title: Randomized controlled trial of taurolidine citrate versus heparin as catheter lock solution in paediatric patients with haematological malignancies.
Journal: The Journal of hospital infection 20120401
Title: Observational study of need for thrombolytic therapy and incidence of bacteremia using taurolidine-citrate-heparin, taurolidine-citrate and heparin catheter locks in patients treated with hemodialysis.
Journal: Seminars in dialysis 20120101
Title: Taurolidine use as a Scolicidal Agent: We Need Different Methodologies.
Journal: Turkiye parazitolojii dergisi 20120101
Title: In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111201
Title: Chemical pleurodesis for the management of refractory hepatic hydrothorax in patients with decompensated liver cirrhosis.
Journal: The Korean journal of hepatology 20111201
Title: Toxicity of antiseptics against chondrocytes: what is best for the cartilage in septic joint surgery?
Journal: International orthopaedics 20111101
Title: [Tunnelled internal jugular vein catheters with taurolidine lock: an acceptable challenge to arterio-venous fistula in 70 years old haemodialyzed patients: a prospective pilot study].
Journal: Nephrologie & therapeutique 20110701
Title: Taurolidine lock - experience from the West of Scotland.
Journal: Clinical nutrition (Edinburgh, Scotland) 20110601
Title: Endotoxin release in cardiac surgery with cardiopulmonary bypass: pathophysiology and possible therapeutic strategies. An update.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20110401
Title: Advances in the diagnosis and management of central venous access device infections in children.
Journal: Advances in experimental medicine and biology 20110101
Title: Unsuccessful application of taurolidine in the treatment of fungal peritonitis in peritoneal dialysis.
Journal: Clinical nephrology 20110101
Title: Animal models of bacterial keratitis.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Animal models of colitis-associated carcinogenesis.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Treatment of long-term catheter-related bloodstream infections with a taurolidine block: a single cancer center experience.
Journal: The journal of vascular access 20110101
Title: Approaches to prolong the use of uncuffed hemodialysis catheters: results of a randomized trial.
Journal: American journal of nephrology 20110101
Title: Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases.
Journal: Journal of toxicology and environmental health. Part B, Critical reviews 20110101
Title: Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric cancer with peritoneal carcinomatosis: evidence from an experimental study.
Journal: Journal of translational medicine 20110101
Title: Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcoma.
Journal: Ultrasound in medicine & biology 20101101
Title: The antiendotoxin agent taurolidine potentially reduces ischemia/reperfusion injury through its metabolite taurine.
Journal: Surgery 20100901
Title: Taurolidine lock is highly effective in preventing catheter-related bloodstream infections in patients on home parenteral nutrition: a heparin-controlled prospective trial.
Journal: Clinical nutrition (Edinburgh, Scotland) 20100801
Title: A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100601
Title: The evolving role of taurolidine in cancer therapy.
Journal: Annals of surgical oncology 20100401
Title: Multimodal approach for treatment of peritoneal surface malignancies in a tumour-bearing rat model.
Journal: International journal of colorectal disease 20100201
Title: Taurolidine antiadhesive properties on interaction with E. coli; its transformation in biological environment and interaction with bacteria cell wall.
Journal: PloS one 20100101
Title: Comparative analysis of cell death induction by Taurolidine in different malignant human cancer cell lines.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Establishment and identification of a rabbit model of peritoneal carcinomatosis from gastric cancer.
Journal: BMC cancer 20100101
Title: Oral administration of the anti-proliferative substance taurolidine has no impact on dextran sulfate sodium induced colitis-associated carcinogenesis in mice.
Journal: Journal of carcinogenesis 20100101
Title: Taurine and the renal system.
Journal: Journal of biomedical science 20100101
Title: [The protoskolicidal effect of 1% polyvinylpyrrolidone-iodine (PVP-1) and 2% taurolidine on abdominal hydatidosis].
Journal: Turkiye parazitolojii dergisi 20100101
Title: Gene expression analysis of cell death induction by taurolidine in different malignant cell lines.
Journal: BMC cancer 20100101
Title: Taurolidine and oxidative stress: a rationale for local treatment of mesothelioma.
Journal: The European respiratory journal 20091201
Title: Taurolidine in the prevention and therapy of lung metastases.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20091201
Title: Principles of the therapy of bone infections in adult extremities : Are there any new developments?
Journal: Strategies in trauma and limb reconstruction (Online) 20091001
Title: Divergent effects of taurolidine as potential anti-neoplastic agent: inhibition of bladder carcinoma cells in vitro and promotion of bladder tumor in vivo.
Journal: Oncology reports 20090801
Title: [Spectrum of indications and perioperative management in i. v. port-a-cath explantation--alternative administration of taurolin in case of i. v. port-a-cath infection].
Journal: Zentralblatt fur Chirurgie 20090801
Title: Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens).
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601
Title: The antibacterial substance taurolidine exhibits anti-neoplastic action based on a mixed type of programmed cell death.
Journal: Autophagy 20090201
Title: Wound healing is not impaired in rats undergoing perioperative treatment with the antineoplastic agent taurolidine.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20090101
Title: Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer: a multicentre prospective randomized trial.
Journal: World journal of surgical oncology 20090101
Title: All-you-can-eat: autophagy in neurodegeneration and neuroprotection.
Journal: Molecular neurodegeneration 20090101
Title: Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Using detachment-promoting agents for the prevention of chronic peritoneal dialysis-associated infections.
Journal: Artificial organs 20081201
Title: Effects of topical application of taurolidine on second intention healing of experimentally induced wounds in rats.
Journal: American journal of veterinary research 20080901
Title: A new haemodialysis catheter-locking agent reduces infections in haemodialysis patients.
Journal: Journal of renal care 20080901
Title: Taurolidine and catheter-related bloodstream infection: a systematic review of the literature.
Journal: Journal of pediatric gastroenterology and nutrition 20080801
Title: Synergistic apoptotic effects of taurolidine and TRAIL on squamous carcinoma cells of the esophagus.
Journal: International journal of oncology 20080601
Title: Novel anti-angiogenic compounds for application in tumor therapy - COP9 signalosome-associated kinases as possible targets.
Journal: Mini reviews in medicinal chemistry 20080501
Title: Re: Endophthalmitis: a review of current evaluation and management.
Journal: Retina (Philadelphia, Pa.) 20080201
Title: The effect of taurolidine on experimental thrombus formation.
Journal: European journal of pharmacology 20080114
Title: An evaluation of normal saline and taurolidine on intra-abdominal adhesion formation and peritoneal fibrinolysis.
Journal: The Journal of surgical research 20080101
Title: Leukopoiesis is not affected after intravenous treatment with the novel antineoplastic agent taurolidine. Results of an experimental study in rats.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20080101
Title: Taurolidine-citrate lock solution (TauroLock) significantly reduces CVAD-associated grampositive infections in pediatric cancer patients.
Journal: BMC infectious diseases 20080101
Title: TRAIL and Taurolidine induce apoptosis and decrease proliferation in human fibrosarcoma.
Journal: Journal of experimental & clinical cancer research : CR 20080101
Title: The tumor suppressive reagent taurolidine inhibits growth of malignant melanoma--a mouse model.
Journal: The Journal of surgical research 20071201
Title: Intra-abdominal use of taurolidine or heparin as alternative products to an antiadhesive barrier (Seprafilm) in adhesion prevention: an experimental study on mice.
Journal: Diseases of the colon and rectum 20071201
Title: Taurolidine induces apoptosis of murine melanoma cells in vitro and in vivo by modulation of the Bcl-2 family proteins.
Journal: Journal of surgical oncology 20070901
Title: Taurolidine: a novel anti-neoplastic agent induces apoptosis of osteosarcoma cell lines.
Journal: Investigational new drugs 20070801
Title: Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia.
Journal: International journal of colorectal disease 20070701
Title: Taurolidine and povidone-iodine induce different types of cell death in malignant pleural mesothelioma.
Journal: Lung cancer (Amsterdam, Netherlands) 20070601
Title: The pharmacokinetics of taurolidine metabolites in healthy volunteers.
Journal: Journal of clinical pharmacology 20070601
Title: Local recurrence model of malignant pleural mesothelioma for investigation of intrapleural treatment.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20070501
Title: Influence of intraperitoneal application of taurolidine/heparin on expression of adhesion molecules and colon cancer in rats undergoing laparoscopy.
Journal: The Journal of surgical research 20070101
Title: Instillation of taurolidine/heparin after laparotomy reduces intraperitoneal tumour growth in a colon cancer rat model.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101
Title: Pharmacokinetics of taurolidine following repeated intravenous infusions measured by HPLC-ESI-MS/MS of the derivatives taurultame and taurinamide in glioblastoma patients.
Journal: Clinical pharmacokinetics 20070101
Title: Is Taurolidine a candidate for treatment of rheumatoid arthritis?
Journal: Clinical and experimental rheumatology 20070101
Title: Treatment of multiple liver metastasis from gastric carcinoma.
Journal: World journal of surgical oncology 20070101
Title: Noninvasive monitoring of myocardial function after surgical and cytostatic therapy in a peritoneal metastasis rat model: assessment with tissue Doppler and non-Doppler 2D strain echocardiography.
Journal: Cardiovascular ultrasound 20070101
Title: Estimating in vivo airway surface liquid concentration in trials of inhaled antibiotics.
Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20070101
Title: Oral administration of taurolidine ameliorates chronic DSS colitis in mice.
Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20070101
Title: Synergistic effects in apoptosis induction by taurolidine and TRAIL in HCT-15 colon carcinoma cells.
Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20070101
Title: Diagnosis and treatment of catheter-related infections in paediatric oncology: an update.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060701
Title: Co-immunotherapy with interleukin-2 and taurolidine for progressive metastatic melanoma.
Journal: Irish journal of medical science 20060101
Title: Effect of peritoneal lavage with taurolidine on primary colonic anastomosis in a rat model of secondary peritonitis.
Journal: Surgery today 20060101
Title: Prevention of disease progression in a patient with a gastric cancer-re-recurrence. Outcome after intravenous treatment with the novel antineoplastic agent taurolidine. Report of a case.
Journal: World journal of surgical oncology 20060101
Title: Hyaluronic acid/carboxymethylcellulose membrane barrier versus taurolidine for the prevention of adhesions to polypropylene mesh.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20060101
Title: Catheter lock solutions: it's time for a change.
Journal: The journal of vascular access 20060101
Title: Anti-inflammatory effects of taurine derivatives (taurine chloramine, taurine bromamine, and taurolidine) are mediated by different mechanisms.
Journal: Advances in experimental medicine and biology 20060101
Title: High doses of taurolidine inhibit advanced intraperitoneal tumor growth in rats.
Journal: The Journal of surgical research 20051101
Title: [Diagnostics and management of central venous line infections in pediatric cancer patients].
Journal: Klinische Padiatrie 20051101
Title: Taurolidine--a new drug with anti-tumor and anti-angiogenic effects.
Journal: Anti-cancer drugs 20051001
Title: Taurolidine lock: the key to prevention of recurrent catheter-related bloodstream infections.
Journal: Clinical nutrition (Edinburgh, Scotland) 20050601
Title: Peritoneal taurolidine lavage in children with localised peritonitis due to appendicitis.
Journal: Pediatric surgery international 20050601
Title: Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.
Journal: Journal of neurosurgery 20050601
Title: Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer.
Journal: Investigational new drugs 20050301
Title: Effectiveness of topical taurolidine versus ciprofloxacin, ofloxacin, and fortified cefazolin in a rabbit Staphylococcus aureus keratitis model.
Journal: Current eye research 20050301
Title: Comment on 'in vivo effects of fluoroquinolones on rabbit corneas'.
Journal: Clinical & experimental ophthalmology 20050201
Title: Impact of taurolidine on the growth of CC531 coloncarcinoma cells in vitro and in a laparoscopic animal model in rats.
Journal: Surgical endoscopy 20050201
Title: Effects of increasing doses of a bolus injection and an intravenous long-term therapy of taurolidine on subcutaneous (metastatic) tumor growth in rats.
Journal: Clinical & experimental metastasis 20050101
Title: The effects of taurolidine, a novel antineoplastic agent, on human malignant mesothelioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041115
Title: The tumor-suppressive reagent taurolidine is an inhibitor of protein biosynthesis.
Journal: International journal of cancer 20041101
Title: Dialysis catheter-related bacteremia: treatment and prophylaxis.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20041101
Title: Taurolidine is effective in the treatment of central venous catheter-related bloodstream infections in cancer patients.
Journal: International journal of antimicrobial agents 20041101
Title: Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer.
Journal: Cancer chemotherapy and pharmacology 20040901
Title: Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040601
Title: Irrigation of port sites: prevention of port site metastases?
Journal: Journal of laparoendoscopic & advanced surgical techniques. Part A 20040601
Title: Intravitreal taurolidine against experimental Staphylococcus epidermidis endophthalmitis in rabbits.
Journal: Current eye research 20040401
Title: Treatment of glioblastoma with intravenous taurolidine. First clinical experience.
Journal: Anticancer research 20040101
Title: Taurolidine-Fibrin-Sealant-Matrix using spray application for local treatment of brain tumors.
Journal: Anticancer research 20040101
Title: Challenges in ocular infectious diseases and the evolution of anti-infective therapy.
Journal: Survey of ophthalmology 20040101
Title: Effects of taurolidine and octreotide on tumor growth and lipid peroxidation after staging-laparoscopy in ductal pancreatic cancer.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20031001
Title: Taurine: new implications for an old amino acid.
Journal: FEMS microbiology letters 20030926
Title: The influence of adhesion prophylactic substances and taurolidine/heparin on local recurrence and intraperitoneal tumor growth after laparoscopic-assisted bowel resection of colon carcinoma in a rat model.
Journal: Surgical endoscopy 20030701
Title: Prophylaxis against dialysis catheter-related bacteremia with a novel antimicrobial lock solution.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030615
Title: Stability and in vitro efficacy of antibiotic-heparin lock solutions potentially useful for treatment of central venous catheter-related sepsis.
Journal: The Journal of antimicrobial chemotherapy 20030401
Title: The effect of Taurolidine on adherent and floating subpopulations of melanoma cells.
Journal: Anti-cancer drugs 20030401
Title: [In vitro effect of taurolidine on squamous cell carcinoma in the oral cavity].
Journal: Mund-, Kiefer- und Gesichtschirurgie : MKG 20030301
Title: Enhancement of Fas-ligand-mediated programmed cell death by taurolidine.
Journal: Anticancer research 20030101
Title: Local and systemic chemotherapy with taurolidine and taurolidine/heparin in colon cancer-bearing rats undergoing laparotomy.
Journal: Clinical & experimental metastasis 20030101
Title: Novel therapies for sepsis: antiendotoxin therapies.
Journal: Expert opinion on investigational drugs 20021201
Title: Granulocyte colony-stimulating factor but not peritoneal lavage increases survival rate after experimental abdominal contamination and infection.
Journal: The British journal of surgery 20021101
Title: Activity of disinfectants against Gram-negative bacilli isolated from patients undergoing lung transplantation for cystic fibrosis.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20021101
Title: Taurolidine attenuates the hemodynamic and respiratory changes associated with endotoxemia.
Journal: Shock (Augusta, Ga.) 20020401
Title: Taurolidine: preclinical evaluation of a novel, highly selective, agent for bone marrow purging.
Journal: Bone marrow transplantation 20020201
Title: Prevention of hemodialysis catheter-related bloodstream infection using an antimicrobial lock.
Journal: Blood purification 20020101
Title: Effects of taurolidine and octreotide on port site and liver metastasis after laparoscopy in an animal model of pancreatic cancer.
Journal: Clinical & experimental metastasis 20020101
Title: A randomized double-blinded placebo-controlled crossover trial of nebulized taurolidine in adult cystic fibrosis patients infected with Burkholderia cepacia.
Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20020101
Title: The effect of taurolidine on brain tumor cells.
Journal: Anticancer research 20020101
Title: The antibacterial drug taurolidine induces apoptosis by a mitochondrial cytochrome c-dependent mechanism.
Journal: Anticancer research 20020101
Title: Influence of antiseptic agents on interleukin-8 release and transmigration of polymorphonuclear neutrophils in a human in vitro model of peritonitis.
Journal: Surgical infections 20020101
Title: Taurolidine improves survival by abrogating the accelerated development and proliferation of solid tumors and development of organ metastases from circulating tumor cells released following surgery.
Journal: The Journal of surgical research 20011201
Title: Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent.
Journal: Cancer research 20010915
Title: [Experimental study of antiseptic (tauroline, taurolidine) and antibiotic (sulmycin implant) drugs in vascular prosthesis infections in a standardized infection model].
Journal: Zentralblatt fur Chirurgie 20010501
Title: Two years' experience with Dialock and CLS (a new antimicrobial lock solution).
Journal: Blood purification 20010101
Title: Haro C, et al. Taurolidine, an antiseptic for the prevention of central venous catheter-related infections. Rev Chilena Infectol. 2019 Aug;36(4):414-420.
Title: Stendel R, et al. Treatment of glioblastoma with intravenous taurolidine. First clinical experience. Anticancer Res. 2004 Mar-Apr;24(2C):1143-7.
