Home Other Building Blocks 1948-33-0
1948-33-0,MFCD00002344
Catalog No.:AA0035KS

1948-33-0 | tert-Butylhydroquinone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25g
98%
in stock  
$6.00   $4.00
- +
500g
98%
in stock  
$33.00   $23.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0035KS
Chemical Name:
tert-Butylhydroquinone
CAS Number:
1948-33-0
Molecular Formula:
C10H14O2
Molecular Weight:
166.2170
MDL Number:
MFCD00002344
SMILES:
Oc1ccc(c(c1)C(C)(C)C)O
NSC Number:
4972
Properties
Properties
 
BP:
276.281°C at 760 mmHg  
Form:
Solid  
MP:
127-129 °C(lit.);  
Refractive Index:
1.4859 (estimate)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
148  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
2.8  

Literature

Title: Tert-butylhydroquinone attenuates oxidative stress and inflammation in hypothalamic paraventricular nucleus in high salt-induced hypertension.

Journal: Toxicology letters 20171105

Title: Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress.

Journal: The Journal of pharmacology and experimental therapeutics 20171001

Title: Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway.

Journal: Environmental toxicology 20170801

Title: Tert-butylhydroquinone protects PC12 cells against ferrous sulfate-induced oxidative and inflammatory injury via the Nrf2/ARE pathway.

Journal: Chemico-biological interactions 20170801

Title: The electrophilic character of quinones is essential for the suppression of Bach1.

Journal: Toxicology 20170715

Title: Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II.

Journal: Archives of toxicology 20170101

Title: Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures.

Journal: Toxicology and applied pharmacology 20161115

Title: P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2.

Journal: Chemical research in toxicology 20160516

Title: Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes.

Journal: Free radical biology & medicine 20160501

Title: 10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress.

Journal: Toxicology and applied pharmacology 20160401

Title: Erk-Creb pathway suppresses glutathione-S-transferase pi expression under basal and oxidative stress conditions in zebrafish embryos.

Journal: Toxicology letters 20160105

Title: Nrf2-dependent repression of interleukin-12 expression in human dendritic cells exposed to inorganic arsenic.

Journal: Free radical biology & medicine 20151101

Title: Protective roles of aldo-keto reductase 1B10 and autophagy against toxicity induced by p-quinone metabolites of tert-butylhydroquinone in lung cancer A549 cells.

Journal: Chemico-biological interactions 20150605

Title: Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.

Journal: Environmental health perspectives 20150501

Title: Solanesol protects human hepatic L02 cells from ethanol-induced oxidative injury via upregulation of HO-1 and Hsp70.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150401

Title: Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line.

Journal: Toxicology and applied pharmacology 20141115

Title: Cooperation of structurally different aryl hydrocarbon receptor agonists and β-catenin in the regulation of CYP1A expression.

Journal: Toxicology 20141105

Title: Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells.

Journal: British journal of cancer 20140826

Title: Regulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping.

Journal: Molecular pharmacology 20140801

Title: Tert-butylhydroquinone as a phenolic activator of Nrf2 antagonizes arsenic-induced oxidative cytotoxicity but promotes arsenic methylation and detoxication in human hepatocyte cell line.

Journal: Biological trace element research 20140801

Title: Nrf2 expression and activity in human T lymphocytes: stimulation by T cell receptor activation and priming by inorganic arsenic and tert-butylhydroquinone.

Journal: Free radical biology & medicine 20140601

Title: Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter.

Journal: Biochimica et biophysica acta 20140601

Title: Pau d'arco activates Nrf2-dependent gene expression via the MEK/ERK-pathway.

Journal: The Journal of toxicological sciences 20140401

Title: Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.

Journal: Journal of medicinal chemistry 20140327

Title: Inhibitory effects of tert-butylhydroquinone on osteoclast differentiation via up-regulation of heme oxygenase-1 and down-regulation of HMGB1 release and NFATc1 expression.

Journal: Journal of applied toxicology : JAT 20140101

Title: Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress.

Journal: Journal of pharmacological sciences 20140101

Title: Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes.

Journal: Toxicology and applied pharmacology 20131215

Title: Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages.

Journal: Toxicology and applied pharmacology 20131101

Title: The Nrf2 activator, tBHQ, differentially affects early events following stimulation of Jurkat cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101

Title: Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells.

Journal: Pharmacological research 20131001

Title: Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways.

Journal: Toxicology and applied pharmacology 20130901

Title: Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells.

Journal: Biochemistry 20130730

Title: Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner.

Journal: Molecular and cellular biology 20130601

Title: Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.

Journal: Antioxidants & redox signaling 20130110

Title: Fast analysis of synthetic antioxidants in edible vegetable oil using trilinear component modeling of liquid chromatography-diode array detection data.

Journal: Journal of chromatography. A 20121116

Title: Neuroprotective effects of tert-butylhydroquinone on paraquat-induced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells.

Journal: Archives of toxicology 20121101

Title: Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage.

Journal: Toxicology and applied pharmacology 20121101

Title: Water quality assessment using the AREc32 reporter gene assay indicative of the oxidative stress response pathway.

Journal: Journal of environmental monitoring : JEM 20121101

Title: The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury.

Journal: Neuroscience 20121025

Title: Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity.

Journal: Journal of neurochemistry 20121001

Title: Fast simultaneous determination of BHA and TBHQ antioxidants in biodiesel by batch injection analysis using pulsed-amperometric detection.

Journal: Talanta 20120915

Title: Paradoxical cytotoxicity of tert-butylhydroquinone in vitro: What kills the untreated cells?

Journal: Archives of toxicology 20120901

Title: An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses.

Journal: Free radical biology & medicine 20120815

Title: Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.

Journal: Free radical biology & medicine 20120815

Title: Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan.

Journal: American journal of physiology. Endocrinology and metabolism 20120815

Title: Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.

Journal: Free radical biology & medicine 20120815

Title: Nrf2-ARE pathway regulates induction of Sestrin-2 expression.

Journal: Free radical biology & medicine 20120815

Title: Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20120701

Title: Oxidative stability of virgin olive oil as affected by the bene unsaponifiable matters and tertiary-butylhydroquinone.

Journal: Journal of food science 20120601

Title: Effects of oxidative stress caused by tert-butylhydroquinone on cytotoxicity in MDCK cells.

Journal: The Journal of veterinary medical science 20120501

Title: Modulation of transcription factor Nrf2 in an in vitro model of traumatic brain injury.

Journal: Journal of neurotrauma 20120410

Title: Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes.

Journal: Environmental health perspectives 20120401

Title: Determination of lutein by high-performance thin-layer chromatography using densitometry and screening of major dietary carotenoids in food supplements.

Journal: Journal of chromatography. A 20120330

Title: Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis.

Journal: The Journal of biological chemistry 20120323

Title: 4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling.

Journal: Free radical biology & medicine 20120315

Title: In vitro bioassay for reactive toxicity towards proteins implemented for water quality monitoring.

Journal: Journal of environmental monitoring : JEM 20120301

Title: Reduction of misleading ('false') positive results in mammalian cell genotoxicity assays. I. Choice of cell type.

Journal: Mutation research 20120218

Title: Th2 skewing by activation of Nrf2 in CD4(+) T cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20120215

Title: Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).

Journal: The Journal of biological chemistry 20120210

Title: A synthetic chalcone as a potent inducer of glutathione biosynthesis.

Journal: Journal of medicinal chemistry 20120209

Title: Tert-Butylhydroquinone pretreatment protects kidney from ischemia-reperfusion injury.

Journal: Journal of nephrology 20120101

Title: The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101

Title: Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms.

Journal: International journal of tryptophan research : IJTR 20120101

Title: Reduction of cytotoxic p-quinone metabolites of tert-butylhydroquinone by human aldo-keto reductase (AKR) 1B10.

Journal: Drug metabolism and pharmacokinetics 20120101

Title: Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway.

Journal: PloS one 20120101

Title: Prevention of diabetic complications by activation of Nrf2: diabetic cardiomyopathy and nephropathy.

Journal: Experimental diabetes research 20120101

Title: Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Visible-light-promoted degradation of the antioxidants propyl gallate and t-butylhydroquinone: mechanistic aspects.

Journal: Redox report : communications in free radical research 20120101

Title: Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway.

Journal: PloS one 20120101

Title: Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis.

Journal: The Journal of biological chemistry 20111230

Title: Polyphenols activate Nrf2 in astrocytes via H2O2, semiquinones, and quinones.

Journal: Free radical biology & medicine 20111215

Title: Free-radical scavenging properties and reducing power of grape cane extracts from 11 selected grape cultivars widely grown in China.

Journal: Molecules (Basel, Switzerland) 20111206

Title: A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes.

Journal: American journal of physiology. Endocrinology and metabolism 20111201

Title: Evaluation of polyphenol contents in differently processed apricots using accelerated solvent extraction followed by high-performance liquid chromatography-diode array detector.

Journal: International journal of food sciences and nutrition 20111101

Title: Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20111101

Title: Preventive effect of tert-butylhydroquinone on cisplatin-induced nephrotoxicity in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111001

Title: Calcium fluxes into and out of cytosol in human platelets: analysis of experimental data.

Journal: Biochemical and biophysical research communications 20110909

Title: Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.

Journal: Disease models & mechanisms 20110901

Title: Unveiling the roles of the glutathione redox system in vivo by analyzing genetically modified mice.

Journal: Journal of clinical biochemistry and nutrition 20110901

Title: Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.

Journal: Toxicology and applied pharmacology 20110815

Title: NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage.

Journal: Archives of toxicology 20110801

Title: Acidic Ca(2+) stores in platelets.

Journal: Cell calcium 20110801

Title: Stabilization of Nrf2 by tBHQ prevents LPS-induced apoptosis in differentiated PC12 cells.

Journal: Molecular and cellular biochemistry 20110801

Title: Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01.

Journal: Biochimica et biophysica acta 20110801

Title: tert-Butylhydroquinone as a spectroscopic probe for the superoxide radical scavenging activity assay of biological samples.

Journal: Analytical chemistry 20110715

Title: Effect of antioxidants on soy oil conjugated linoleic acid production and its oxidative stability.

Journal: Journal of agricultural and food chemistry 20110713

Title: Protective effect of tert-butylhydroquinone on cerebral inflammatory response following traumatic brain injury in mice.

Journal: Injury 20110701

Title: Pressurized liquid extraction of phenolic compounds from Anatolia propolis and their radical scavenging capacities.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

Title: [Terahertz spectroscopic testing of food additive tert-butylhydroquinone].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20110701

Title: Fish oil and olive oil can modify insulin resistance and plasma desacyl-ghrelin in rats.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110701

Title: The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics.

Journal: Chemico-biological interactions 20110630

Title: Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway.

Journal: Blood 20110602

Title: tBHQ-induced HO-1 expression is mediated by calcium through regulation of Nrf2 binding to enhancer and polymerase II to promoter region of HO-1.

Journal: Chemical research in toxicology 20110516

Title: Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway.

Journal: Cellular signalling 20110501

Title: Dietary supplementation with tBHQ, an Nrf2 stabilizer molecule, confers neuroprotection against apoptosis in amyloid β-injected rat.

Journal: Neurochemical research 20110501

Title: The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK.

Journal: Glia 20110501

Title: Discovery of novel SERCA inhibitors by virtual screening of a large compound library.

Journal: European journal of medicinal chemistry 20110501

Title: [Antagonism of tert-butylhydroquinone on neurotoxicity and oxidative stress induced by paraquat in PC12].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20110401

Title: INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis.

Journal: Cell death and differentiation 20110301

Title: Monitoring the intracellular store Ca2+ concentration in agonist-stimulated, intact human platelets by using Fluo-5N.

Journal: Journal of thrombosis and haemostasis : JTH 20110301

Title: [Effects of tert-butylhydroquinone on oxidative stress in kidneys of diabetic mice].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20110301

Title: Suppression of CFTR-mediated Cl secretion of airway epithelium in vitamin C-deficient mice.

Journal: Journal of Korean medical science 20110301

Title: [Determination of antioxidant residues in polymer food package using gas chromatography].

Journal: Se pu = Chinese journal of chromatography 20110301

Title: Identification of clinically used drugs that activate pregnane X receptors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior.

Journal: BMC systems biology 20110101

Title: Stabilization of Nrf2 protein by D3T provides protection against ethanol-induced apoptosis in PC12 cells.

Journal: PloS one 20110101

Title: Attenuation of glomerular injury in diabetic mice with tert-butylhydroquinone through nuclear factor erythroid 2-related factor 2-dependent antioxidant gene activation.

Journal: American journal of nephrology 20110101

Title: The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.

Journal: Parkinson's disease 20110101

Title: Cloud-point extraction and reversed-phase high-performance liquid chromatography for the determination of synthetic phenolic antioxidants in edible oils.

Journal: Journal of food science 20110101

Title: Preventive effect of pine bark extract (flavangenol) on metabolic disease in Western diet-loaded tsumura suzuki obese diabetes mice.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Polyphenolic contents and antioxidant potential of stem bark extracts from Jatropha curcas (Linn).

Journal: International journal of molecular sciences 20110101

Title: BTZO-15, an ARE-activator, ameliorates DSS- and TNBS-induced colitis in rats.

Journal: PloS one 20110101

Title: Therapeutic potential and anti-amyloidosis mechanisms of tert-butylhydroquinone for Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Antioxidant, antimicrobial and antiproliferative activities of five lichen species.

Journal: International journal of molecular sciences 20110101

Title: Dietary saturated and monounsaturated fats protect against acute acetaminophen hepatotoxicity by altering fatty acid composition of liver microsomal membrane in rats.

Journal: Lipids in health and disease 20110101

Title: Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis.

Journal: PloS one 20110101

Title: The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia.

Journal: PloS one 20110101

Title: Nuclear Factor-κB modulates cellular glutathione and prevents oxidative stress in cancer cells.

Journal: Cancer letters 20101218

Title: Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia.

Journal: Circulation research 20101210

Title: Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.

Journal: Chemico-biological interactions 20101205

Title: Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation.

Journal: Cell biology and toxicology 20101201

Title: Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.

Journal: Biochemistry 20101005

Title: Multiple anticancer activities of EF24, a novel curcumin analog, on human ovarian carcinoma cells.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20101001

Title: Direct amperometric determination of tert-butylhydroquinone in biodiesel.

Journal: Talanta 20100915

Title: Induction of cereblon by NF-E2-related factor 2 in neuroblastoma cells exposed to hypoxia-reoxygenation.

Journal: Biochemical and biophysical research communications 20100903

Title: Seasonal variation, chemical composition and antioxidant activity of Brazilian propolis samples.

Journal: Evidence-based complementary and alternative medicine : eCAM 20100901

Title: After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult.

Journal: Free radical biology & medicine 20100901

Title: Voltammetric determination of tert-butylhydroquinone in biodiesel using a carbon paste electrode in the presence of surfactant.

Journal: Colloids and surfaces. B, Biointerfaces 20100901

Title: Comparison of current docking tools for the simulation of inhibitor binding by the transmembrane domain of the sarco/endoplasmic reticulum calcium ATPase.

Journal: Biophysical chemistry 20100801

Title: Direct spectroscopic observation of singlet oxygen quenching and kinetic studies of physical and chemical singlet oxygen quenching rate constants of synthetic antioxidants (BHA, BHT, and TBHQ) in methanol.

Journal: Journal of food science 20100801

Title: The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.

Journal: The Journal of biological chemistry 20100723

Title: An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

Journal: Journal of natural products 20100723

Title: An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.

Journal: The Journal of biological chemistry 20100709

Title: Induction of the Nrf2-driven antioxidant response by tert-butylhydroquinone prevents ethanol-induced apoptosis in cranial neural crest cells.

Journal: Biochemical pharmacology 20100701

Title: Determination of food grade antioxidants using microemulsion electrokinetic chromatography.

Journal: Electrophoresis 20100701

Title: [Patch testing in patients with leg ulcers with special regard to modern wound products].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20100701

Title: Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.

Journal: Journal of proteomics 20100616

Title: Antioxidant activity and chemical composition of the fractions from burdock leaves.

Journal: Journal of food science 20100601

Title: Sodium 2-propenyl thiosulfate derived from garlic induces phase II detoxification enzymes in rat hepatoma H4IIE cells.

Journal: Nutrition research (New York, N.Y.) 20100601

Title: Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway.

Journal: The Journal of biological chemistry 20100528

Title: The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy.

Journal: Diabetes 20100401

Title: Protection by Chrysanthemum zawadskii extract from liver damage of mice caused by carbon tetrachloride is maybe mediated by modulation of QR activity.

Journal: Nutrition research and practice 20100401

Title: Comparing antioxidant effectiveness of natural and synthetic free radical scavengers in thermally-oxidized lard using DPPH method.

Journal: Journal of food science 20100401

Title: The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes.

Journal: The Journal of veterinary medical science 20100301

Title: Stabilization of transcription factor Nrf2 by tBHQ prevents oxidative stress-induced amyloid beta formation in NT2N neurons.

Journal: Biochimie 20100301

Title: Paradoxical roles for antioxidants in tumor prevention and eradication.

Journal: Cancer biology & therapy 20100301

Title: Keap1-Nrf2 activation in the presence and absence of DJ-1.

Journal: The European journal of neuroscience 20100301

Title: Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10.

Journal: The Journal of biological chemistry 20100226

Title: Transcriptional regulation of human carboxylesterase 1A1 by nuclear factor-erythroid 2 related factor 2 (Nrf2).

Journal: Biochemical pharmacology 20100115

Title: The characteristics of performance and exhaust emissions of a diesel engine using a biodiesel with antioxidants.

Journal: Bioresource technology 20100101

Title: Protective effect of tert-butylhydroquinone on the quinolinic-acid-induced toxicity in rat striatal slices: role of the Nrf2-antioxidant response element pathway.

Journal: Neuro-Signals 20100101

Title: Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.

Journal: The Journal of pharmacology and experimental therapeutics 20100101

Title: Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.

Journal: The Journal of biological chemistry 20100101

Title: Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice.

Journal: PloS one 20100101

Title: [Effect of tBHQ and sulforaphane on Nrf2-ARE signaling pathway of Caco2 cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20100101

Title: Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

Journal: BMC medical genetics 20100101

Title: Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.

Journal: BMC neuroscience 20100101

Title: Dietary phytosterols and phytostanols decrease cholesterol levels but increase blood pressure in WKY inbred rats in the absence of salt-loading.

Journal: Nutrition & metabolism 20100101

Title: Peroxisome proliferator-activated receptors (PPARs)-independent functions of fish oil on glucose and lipid metabolism in diet-induced obese mice.

Journal: Lipids in health and disease 20100101

Title: Stem cells for spinal cord regeneration: Current status.

Journal: Surgical neurology international 20100101

Title: Effects of tert-butylhydroquinone on intestinal inflammatory response and apoptosis following traumatic brain injury in mice.

Journal: Mediators of inflammation 20100101

Title: Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.

Journal: Journal of cell science 20091215

Title: NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation.

Journal: Molecular pharmacology 20091201

Title: Genomic analyses reveal a conserved glutathione homeostasis pathway in the invertebrate chordate Ciona intestinalis.

Journal: Physiological genomics 20091101

Title: Oxidative stability and alpha-tocopherol retention in soybean oil with lemon seed extract (Citrus limon) under thermoxidation.

Journal: Natural product communications 20091101

Title: [Protective effect of tert-butylhydroquinone on PC12 cells from neurotoxicity induced by manganese in vitro].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20091001

Title: Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901

Title: Identification and characterization of an Nrf2-mediated ARE upstream of the rat glutamate cysteine ligase catalytic subunit gene (GCLC).

Journal: Journal of cellular biochemistry 20090801

Title: Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.

Journal: Free radical biology & medicine 20090615

Title: Kinetic study of the quenching reaction of singlet oxygen by common synthetic antioxidants (tert-butylhydroxyanisol, tert-di-butylhydroxytoluene, and tert-butylhydroquinone) as compared with alpha-tocopherol.

Journal: Journal of food science 20090601

Title: Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures.

Journal: Journal of neuroscience research 20090515

Title: Induction of metallothionein I by arsenic via metal-activated transcription factor 1: critical role of C-terminal cysteine residues in arsenic sensing.

Journal: The Journal of biological chemistry 20090508

Title: Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.

Journal: The Journal of biological chemistry 20090417

Title: Relationships between free radical scavenging and antioxidant activity in foods.

Journal: Journal of agricultural and food chemistry 20090408

Title: Role of iron and hydroperoxides in the degradation of lycopene in oil-in-water emulsions.

Journal: Journal of agricultural and food chemistry 20090408

Title: Skin fibroblast model to study an impaired glutathione synthesis: consequences of a genetic polymorphism on the proteome.

Journal: Brain research bulletin 20090406

Title: Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice.

Journal: Toxicology letters 20090328

Title: Lipophilicity data for some preservatives estimated by reversed-phase liquid chromatography and different computation methods.

Journal: Journal of chromatography. A 20090320

Title: Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications.

Journal: Molecular biology of the cell 20090315

Title: tBHQ inhibits LPS-induced microglial activation via Nrf2-mediated suppression of p38 phosphorylation.

Journal: Biochemical and biophysical research communications 20090313

Title: The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors.

Journal: The Biochemical journal 20090301

Title: Expression of sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) 3 proteins in two major conformational states in native human cell membranes.

Journal: Biochimica et biophysica acta 20090301

Title: Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.

Journal: Journal of neurochemistry 20090301

Title: Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress.

Journal: Free radical biology & medicine 20090215

Title: Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation.

Journal: Biochemical and biophysical research communications 20090206

Title: HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090201

Title: Role of hepatitis B virus X repression of C/EBPbeta activity in the down-regulation of glutathione S-transferase A2 gene: implications in other phase II detoxifying enzyme expression.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20090201

Title: Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element.

Journal: Free radical biology & medicine 20090115

Title: Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia.

Journal: PloS one 20090101

Title: Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells.

Journal: Journal of biomedical science 20090101

Title: Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.

Journal: PloS one 20090101

Title: Methamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatum.

Journal: PloS one 20090101

Title: Storage stability of sunflower oil with added natural antioxidant concentrate from sesame seed oil.

Journal: Journal of oleo science 20090101

Title: Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response.

Journal: PloS one 20090101

Title: LAS0811: from combinatorial chemistry to activation of antioxidant response element.

Journal: Journal of biomedicine & biotechnology 20090101

Title: Inflammatory mechanisms in ischemic stroke: therapeutic approaches.

Journal: Journal of translational medicine 20090101

Title: Diets with corn oil and/or low protein increase acute acetaminophen hepatotoxicity compared to diets with beef tallow in a rat model.

Journal: Nutrition research and practice 20090101

Title: Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress.

Journal: Neuroscience letters 20081212

Title: Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis.

Journal: British journal of cancer 20081209

Title: Effect of homocysteine on calcium mobilization and platelet function in type 2 diabetes mellitus.

Journal: Journal of cellular and molecular medicine 20081201

Title: Methyl methacrylate activates the Gsta1 promoter.

Journal: Journal of dental research 20081201

Title: Proposed mechanism of inactivating Escherichia coli O157:H7 by ultra-high pressure in combination with tert-butylhydroquinone.

Journal: Journal of applied microbiology 20081201

Title: Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20081118

Title: Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

Journal: Molecular and cellular neurosciences 20081101

Title: Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione.

Journal: Journal of neurochemistry 20081001

Title: Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes.

Journal: Journal of neurochemistry 20080901

Title: Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.

Journal: Free radical biology & medicine 20080815

Title: The neuroprotective potential of phase II enzyme inducer on motor neuron survival in traumatic spinal cord injury in vitro.

Journal: Cellular and molecular neurobiology 20080801

Title: Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction.

Journal: Toxicology and applied pharmacology 20080801

Title: Metabolic kinetics of tert-butylhydroquinone and its metabolites in rat serum after oral administration by LC/ITMS.

Journal: Lipids 20080801

Title: Activation of Nrf2 in defense against cadmium-induced oxidative stress.

Journal: Chemical research in toxicology 20080701

Title: Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2.

Journal: Carcinogenesis 20080601

Title: STIM1 regulates acidic Ca2+ store refilling by interaction with SERCA3 in human platelets.

Journal: Biochemical pharmacology 20080601

Title: Inactivation of barotolerant strains of Listeria monocytogenes and Escherichia coli O157:H7 by ultra high pressure and tert-butylhydroquinone combination.

Journal: Journal of microbiology (Seoul, Korea) 20080601

Title: Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501

Title: Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2.

Journal: The Journal of biological chemistry 20080404

Title: Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane.

Journal: Carcinogenesis 20080401

Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Journal: Chemical research in toxicology 20080401

Title: Dicarbonyls stimulate cellular protection systems in primary rat hepatocytes and show anti-inflammatory properties.

Journal: Annals of the New York Academy of Sciences 20080401

Title: Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions.

Journal: The Journal of biological chemistry 20080328

Title: Determination of tertiary-butylhydroquinone and its metabolites in rat serum by liquid chromatography-ion trap mass spectrometry.

Journal: Lipids 20080301

Title: Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid.

Journal: Toxicology and applied pharmacology 20080201

Title: Phosphatidylinositol 4,5-bisphosphate enhances store-operated calcium entry through hTRPC6 channel in human platelets.

Journal: Biochimica et biophysica acta 20080101

Title: Palm-based standard reference materials for iodine value and slip melting point.

Journal: Analytical chemistry insights 20080101

Title: Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.

Journal: Toxicology and applied pharmacology 20071201

Title: Melissoidesin G, a diterpenoid purified from Isodon melissoides, induces leukemic-cell apoptosis through induction of redox imbalance and exhibits synergy with other anticancer agents.

Journal: International journal of cancer 20071101

Title: Capillary electrophoresis coupled with electrochemical detection using porous etched joint for determination of antioxidants.

Journal: Journal of chromatography. A 20071005

Title: Antiaggregant effects of Arbutus unedo extracts in human platelets.

Journal: Journal of ethnopharmacology 20070905

Title: NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells.

Journal: Chemical research in toxicology 20070901

Title: Protection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070701

Title: Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.

Journal: Neuroscience 20070615

Title: Induction of phase I and II drug metabolism in rat small intestine and colon in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601

Title: Spectrophotometric determination of phenolic compounds by enzymatic and chemical methods--a comparison of structure--activity relationship.

Journal: Journal of agricultural and food chemistry 20070516

Title: Nrf2-mediated protection against 6-hydroxydopamine.

Journal: Brain research 20070504

Title: Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070401

Title: Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice.

Journal: The Journal of biological chemistry 20070323

Title: OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids.

Journal: Journal of lipid research 20070301

Title: Synthesis and antioxidant activity evaluation of new 7-aryl or 7-heteroarylamino-2,3-dimethylbenzo[b]thiophenes obtained by Buchwald-Hartwig C-N cross-coupling.

Journal: Bioorganic & medicinal chemistry 20070215

Title: Allergic contact dermatitis from tertiary-butylhydroquinone and Laureth 12 in a hair dye.

Journal: Contact dermatitis 20070201

Title: Chemoprotective and carcinogenic effects of tert-butylhydroquinone and its metabolites.

Journal: Current drug metabolism 20070101

Title: Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo.

Journal: Genome biology 20070101

Title: Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress.

Journal: Journal of experimental therapeutics & oncology 20070101

Title: Genomic loci modulating the retinal transcriptome in wound healing.

Journal: Gene regulation and systems biology 20070101

Title: Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes.

Journal: Cancer letters 20061208

Title: Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes.

Journal: Pharmaceutical research 20061101

Title: Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain.

Journal: The Journal of biological chemistry 20060915

Title: The tert-butylhydroquinone-mediated activation of the human thioredoxin gene reveals a novel promoter structure.

Journal: The Biochemical journal 20060901

Title: Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

Journal: The Journal of biological chemistry 20060818

Title: Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.

Journal: Biochemical pharmacology 20060714

Title: Regulation of CYP1A1 gene expression by the antioxidant tert-butylhydroquinone.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Longevity in mice: is stress resistance a common factor?

Journal: Age (Dordrecht, Netherlands) 20060601

Title: Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.

Journal: Carcinogenesis 20060501

Title: Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis.

Journal: Journal of neurochemistry 20060501

Title: Nuclear factor Nrf2 and antioxidant response element regulate NRH:quinone oxidoreductase 2 (NQO2) gene expression and antioxidant induction.

Journal: Free radical biology & medicine 20060401

Title: Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets.

Journal: Cellular signalling 20060301

Title: [Protective effect of tert-butylhydroquinone on bone marrow cells in rats from cytotoxicity induced by benzene in vitro].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060301

Title: Use of phenolic compounds for sensitizing Listeria monocytogenes to high-pressure processing.

Journal: International journal of food microbiology 20060215

Title: Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation.

Journal: Archives of biochemistry and biophysics 20060215

Title: Oxidant stress suppresses CFTR expression.

Journal: American journal of physiology. Cell physiology 20060101

Title: Effect of plant extracts on physicochemical properties of chicken breast meat cooked using conventional electric oven or microwave.

Journal: Poultry science 20060101

Title: Activation of CYP1A1 gene expression during primary culture of mouse hepatocytes.

Journal: Toxicology 20051215

Title: Estimated daily intakes of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ) antioxidants in Korea.

Journal: Food additives and contaminants 20051201

Title: A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051102

Title: A transient treatment of hippocampal neurons with alpha-tocopherol induces a long-lasting protection against oxidative damage via a genomic action.

Journal: Free radical biology & medicine 20051015

Title: Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051001

Title: Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage.

Journal: Journal of neurochemistry 20051001

Title: Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation.

Journal: The Journal of biological chemistry 20050909

Title: Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050901

Title: Ca2+ accumulation into acidic organelles mediated by Ca2+- and vacuolar H+-ATPases in human platelets.

Journal: The Biochemical journal 20050815

Title: Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling.

Journal: The Journal of biological chemistry 20050805

Title: Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

Journal: The Journal of biological chemistry 20050617

Title: Determination and confirmation of five phenolic antioxidants in foods by LC/MS and GC/MS.

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20050601

Title: Determination of antioxidants in cosmetics by micellar electrokinetic capillary chromatography with electrochemical detection.

Journal: Journal of chromatography. A 20050513

Title: Serotonin glucuronidation by Ah receptor- and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells.

Journal: Biochemical pharmacology 20050501

Title: Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression.

Journal: Molecular and cellular biology 20050501

Title: Inactivation of barotolerant Listeria monocytogenes in sausage by combination of high-pressure processing and food-grade additives.

Journal: Journal of food protection 20050401

Title: Dissecting tBHQ induced ARE-driven gene expression through long and short oligonucleotide arrays.

Journal: Physiological genomics 20050321

Title: Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements.

Journal: The Journal of biological chemistry 20050318

Title: tert-Butylhydroquinone is a novel aryl hydrocarbon receptor ligand.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050301

Title: Down-regulation of aryl hydrocarbon receptor-regulated genes by tumor necrosis factor-alpha and lipopolysaccharide in murine hepatoma Hepa 1c1c7 cells.

Journal: Journal of pharmaceutical sciences 20050301

Title: Different cytoprotective effect of antioxidants and change in the iron regulatory system in rodent cells exposed to paraquat or formaldehyde.

Journal: Toxicology 20050301

Title: Induction of phase I, II and III drug metabolism/transport by xenobiotics.

Journal: Archives of pharmacal research 20050301

Title: Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050201

Title: Coordinate regulation of glutathione metabolism in astrocytes by Nrf2.

Journal: Biochemical and biophysical research communications 20050114

Title: Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity-induced by 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) in mice.

Journal: Journal of biochemical and molecular toxicology 20050101

Title: Differential regulation of three genes encoding glutathione S-transferases in Schizosaccharomyces pombe.

Journal: Molecules and cells 20041231

Title: Effect of electron beam irradiation and storage at 5 degrees C on thiobarbituric acid reactive substances and carbonyl contents in chicken breast meat infused with antioxidants and selected plant extracts.

Journal: Journal of agricultural and food chemistry 20041229

Title: Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding.

Journal: Cancer letters 20041228

Title: Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.

Journal: The Journal of biological chemistry 20041203

Title: Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041101

Title: Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism.

Journal: Molecular carcinogenesis 20041101

Title: Optimization of a high-performance liquid chromatography system by artificial neural networks for separation and determination of antioxidants.

Journal: Journal of separation science 20041001

Title: Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate.

Journal: Biochemical and biophysical research communications 20040924

Title: Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: Total phenolics and antioxidant activities of fenugreek, green tea, black tea, grape seed, ginger, rosemary, gotu kola, and ginkgo extracts, vitamin E, and tert-butylhydroquinone.

Journal: Journal of agricultural and food chemistry 20040811

Title: Two pathways for store-mediated calcium entry differentially dependent on the actin cytoskeleton in human platelets.

Journal: The Journal of biological chemistry 20040709

Title: PKC downstream of Pl3-kinase regulates peroxynitrite formation for Nrf2-mediated GSTA2 induction.

Journal: Archives of pharmacal research 20040701

Title: Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc.

Journal: The Biochemical journal 20040615

Title: Ceramide negatively regulates glutathione S-transferase gene transactivation via repression of hepatic nuclear factor-1 that is degraded by the ubiquitin proteasome system.

Journal: Molecular pharmacology 20040601

Title: Determining partition constants of polar organic molecules between the oil/interfacial and water/interfacial regions in emulsions: a combined electrochemical and spectrometric method.

Journal: Langmuir : the ACS journal of surfaces and colloids 20040413

Title: Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.

Journal: Archives of biochemistry and biophysics 20040301

Title: The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.

Journal: Biochemical pharmacology 20040301

Title: Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040204

Title: Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction.

Journal: The Biochemical journal 20040101

Title: Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites.

Journal: Skin pharmacology and physiology 20040101

Title: Increase of antioxidative potential by tert-butylhydroquinone protects against cell death associated with 6-hydroxydopamine-induced oxidative stress in neuroblastoma SH-SY5Y cells.

Journal: Brain research. Molecular brain research 20031126

Title: Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression.

Journal: The Journal of biological chemistry 20031107

Title: A reassessment of the effects of luminal [Ca2+] on inositol 1,4,5-trisphosphate-induced Ca2+ release from internal stores.

Journal: The Journal of biological chemistry 20031010

Title: Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells.

Journal: Biochemical pharmacology 20030901

Title: Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element.

Journal: The Journal of nutrition 20030901

Title: Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression.

Journal: Investigative ophthalmology & visual science 20030801

Title: Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents.

Journal: Biochemical pharmacology 20030701

Title: Testicular toxicity of dibromoacetonitrile and possible protection by tertiary butylhydroquinone.

Journal: Pharmacological research 20030601

Title: Cell death induced by the phenolic antioxidant tert-butylhydroquinone and its metabolite tert-butylquinone in human monocytic leukemia U937 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030501

Title: Thymoquinone is a potent superoxide anion scavenger.

Journal: Drug and chemical toxicology 20030501

Title: Antioxidant activity of 3-dehydroshikimic acid in liposomes, emulsions, and bulk oil.

Journal: Journal of agricultural and food chemistry 20030423

Title: Enhancement of ATRA-induced cell differentiation by inhibition of calcium accumulation into the endoplasmic reticulum: cross-talk between RAR alpha and calcium-dependent signaling.

Journal: Blood 20030415

Title: Pivotal role of electrophilicity in glutathione S-transferase induction by tert-butylhydroquinone.

Journal: Biochemistry 20030415

Title: Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

Title: Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis.

Journal: The Journal of biological chemistry 20030404

Title: Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.

Journal: Life sciences 20030404

Title: Hydrogen peroxide- and cell-density-regulated expression of NADH-cytochrome b5 reductase in HeLa cells.

Journal: Journal of bioenergetics and biomembranes 20030401

Title: Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response.

Journal: Oncogene 20030327

Title: Cyclooxygenase inhibitory and antioxidant compounds from crabapple fruits.

Journal: Journal of agricultural and food chemistry 20030326

Title: Role of NAD(P)H:quinone oxidoreductase in the progression of neuronal cell death in vitro and following cerebral ischaemia in vivo.

Journal: Journal of neurochemistry 20030301

Title: Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.

Journal: The Journal of biological chemistry 20030214

Title: Patch testing with the irritant sodium lauryl sulfate (SLS) is useful in interpreting weak reactions to contact allergens as allergic or irritant.

Journal: Contact dermatitis 20030201

Title: Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress.

Journal: Molecular pharmacology 20021101

Title: Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes.

Journal: Current drug metabolism 20021001

Title: Differential gene expression patterns revealed by oligonucleotide versus long cDNA arrays.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20021001

Title: Role of AP-1 in the coordinate induction of rat glutamate-cysteine ligase and glutathione synthetase by tert-butylhydroquinone.

Journal: The Journal of biological chemistry 20020920

Title: Inhibition of lipid peroxidation and structure-activity-related studies of the dietary constituents anthocyanins, anthocyanidins, and catechins.

Journal: Journal of agricultural and food chemistry 20020911

Title: Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence.

Journal: The Journal of biological chemistry 20020823

Title: Copper redox-dependent activation of 2-tert-butyl(1,4)hydroquinone: formation of reactive oxygen species and induction of oxidative DNA damage in isolated DNA and cultured rat hepatocytes.

Journal: Mutation research 20020725

Title: Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction.

Journal: Circulation 20020625

Title: In vitro induction of the anticarcinogenic marker enzyme, quinone reductase, in human hepatoma cells by food extracts.

Journal: Cancer letters 20020606

Title: Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice.

Journal: Journal of neurochemistry 20020601

Title: Kinetic method for determining antioxidant distributions in model food emulsions: distribution constants of t-butylhydroquinone in mixtures of octane, water, and a nonionic emulsifier.

Journal: Journal of agricultural and food chemistry 20020522

Title: Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress.

Journal: Biochemical pharmacology 20020501

Title: Characterization, quantification, and bioactivities of anthocyanins in Cornus species.

Journal: Journal of agricultural and food chemistry 20020424

Title: Promoting effects of combined antioxidant and sodium nitrite treatment on forestomach carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Cancer letters 20020408

Title: [Simultaneous determination of five antioxidants in food by HPLC with fluorescence detection].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020401

Title: Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression.

Journal: Toxicology 20020227

Title: Ability of surfactant micelles to alter the partitioning of phenolic antioxidants in oil-in-water emulsions.

Journal: Journal of agricultural and food chemistry 20020227

Title: Chemoprotection by phenolic antioxidants. Inhibition of tumor necrosis factor alpha induction in macrophages.

Journal: The Journal of biological chemistry 20020125

Title: Differential induction of mafF, mafG and mafK expression by electrophile-response-element activators.

Journal: The Biochemical journal 20020115

Title: Influence of t-butylhydroquinone and beta-naphthoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers.

Journal: Biochemical pharmacology 20020115

Title: Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form.

Journal: The Journal of biological chemistry 20020111

Title: Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells.

Journal: The Journal of biological chemistry 20020104

Title: Time-dependent changes in ARE-driven gene expression by use of a noise-filtering process for microarray data.

Journal: Physiological genomics 20020101

Title: Cell-based studies reveal differences in glutathione S-transferase induction between oltipraz and tert-butylhydroquinone.

Journal: Journal of biochemical and molecular toxicology 20020101

Title: Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide.

Journal: Endothelium : journal of endothelial cell research 20020101

Title: A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells.

Journal: The Journal of physiology 20011201

Title: Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile.

Journal: Journal of agricultural and food chemistry 20011201

Title: Functional characterization of transcription regulators that interact with the electrophile response element.

Journal: Biochemical and biophysical research communications 20011123

Title: Troglitazone selectively inhibits glyoxalase I gene expression.

Journal: Diabetologia 20011101

Title: [Extraction of the antioxidative substances from Chinese rose and its antioxidative effect on lard].

Journal: Wei sheng yan jiu = Journal of hygiene research 20011101

Title: The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats.

Journal: Journal of hypertension 20011001

Title: Degradation products of cyanidin glycosides from tart cherries and their bioactivities.

Journal: Journal of agricultural and food chemistry 20011001

Title: Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors.

Journal: Molecular pharmacology 20010901

Title: Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20010901

Title: 2,5-Di-tert-butyl-1,4-hydroquinone enhances cell transformation accompanied by an increase in intracellular free calcium ion concentration.

Journal: Cancer letters 20010726

Title: Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.

Journal: Oncogene 20010628

Title: Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells.

Journal: The Journal of biological chemistry 20010608

Title: Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells.

Journal: Molecular pharmacology 20010501

Title: Estimates of the theoretical maximum daily intake of phenolic antioxidants BHA, BHT and TBHQ in Brazil.

Journal: Food additives and contaminants 20010501

Title: Up-regulation of transporters of the MRP family by drugs and toxins.

Journal: Toxicology letters 20010331

Title: Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane.

Journal: Biochemical and biophysical research communications 20010323

Title: Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status.

Journal: Biochemical pharmacology 20010301

Title: Preferential expression of antioxidant response element mediated gene expression in astrocytes.

Journal: Journal of neurochemistry 20010301

Title: Identification of alpha-tocopherol oxidation products in triolein at elevated temperatures.

Journal: Journal of agricultural and food chemistry 20010301

Title: Synthesis and antiperoxidant activity of new phenolic O-glycosides.

Journal: Carbohydrate research 20010227

Title: Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.

Journal: Nature cell biology 20010201

Title: Tyrphostin [correction of Tryphostin] AG879, a tyrosine kinase inhibitor: prevention of transcriptional activation of the electrophile and the aromatic hydrocarbon response elements.

Journal: Biochemical pharmacology 20010115

Title: Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells.

Journal: Biochemical and biophysical research communications 20010112

Title: The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.

Journal: Biochemical and biophysical research communications 20010112

Title: Evaluation of the TOPKAT system for predicting the carcinogenicity of chemicals.

Journal: Environmental and molecular mutagenesis 20010101

Title: Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).

Journal: Drug metabolism reviews 20010101

Title: Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20000915

Title: Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor.

Journal: The Journal of biological chemistry 20000908

Title: Inducers of gamma-glutamylcysteine synthetase and their effects on glutathione synthetase expression.

Journal: Biochimica et biophysica acta 20000907

Title: Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c.

Journal: Molecular pharmacology 20000801

Title: Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene.

Journal: The Journal of biological chemistry 19990910

Title: Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.

Journal: Cancer letters 19990901

Title: Induction of human UDP glucuronosyltransferases (UGT1A6, UGT1A9, and UGT2B7) by t-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin in Caco-2 cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19990501

Title: Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.

Journal: Cancer research 19990201

Title: Human NAD(P)H:quinone oxidoreductase induction in human hepatoma cells after exposure to industrial acrylates, phenolics, and metals.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19970201

Title: Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE).

Journal: Molecular medicine (Cambridge, Mass.) 19951101

Title: Electrophile and antioxidant regulation of enzymes that detoxify carcinogens.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19950912

Title: Regulation of the Ah gene battery via Ah receptor-dependent and independent processes in cultured adult rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19950601

Title: Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines.

Journal: Carcinogenesis 19941001

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:1948-33-0 Molecular Formula|1948-33-0 MDL|1948-33-0 SMILES|1948-33-0 tert-Butylhydroquinone |Organic_Building_Blocks