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195311-28-5,MFCD06653330
Catalog No.:AA00748Z

195311-28-5 | 1-(Pyrrolidin-2-ylmethyl)pyrrolidine

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100mg
95%
in stock  
$77.00   $54.00
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250mg
95%
in stock  
$123.00   $87.00
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1g
95%
in stock  
$311.00   $218.00
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5g
95%
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$912.00   $639.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00748Z
Chemical Name:
1-(Pyrrolidin-2-ylmethyl)pyrrolidine
CAS Number:
195311-28-5
Molecular Formula:
C9H18N2
Molecular Weight:
154.2526
MDL Number:
MFCD06653330
SMILES:
C1CCN(C1)CC1CCCN1
NSC Number:
116549
Properties
Computed Properties
 
Complexity:
119  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.9  

Downstream Synthesis Route

[1]Patent:US5591737,1997,A

[2]Patent:US5747485,1998,A

[1]Jin,Jian;Wang,Yonghui;Wang,Feng;Shi,Dongchuan;Erhard,KarlF.;Wu,Zining;Guida,BrianF.;Lawrence,SarahK.;Behm,DavidJ.;Disa,Jyoti;Vaidya,KalindiS.;Evans,Christopher;McMillan,LynetteJ.;Rivero,RalphA.;Neeb,MichaelJ.;Douglas,StephenA.[BioorganicandMedicinalChemistryLetters,2008,vol.18,#9,p.2860-2864]

Literature

Title: Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS.

Journal: Analytical and bioanalytical chemistry 20121001

Title: Chiral amines as reagents for HPLC-MS enantioseparation of chiral carboxylic acids.

Journal: Journal of separation science 20120701

Title: Amine-constrained pyridazinone histamine H₃ receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20110915

Title: Asymmetric anionic polymerization of 2,7-bis(4-t-butylphenyl)fluoren-9-ylmethyl methacrylate and photoinduced structural transition of the obtained polymer.

Journal: Chirality 20110101

Title: (5S*,6R*,7R*)-6-Formyl-5-phenyl-7-propyl-perhydro-pyrazolo[1,2-a]pyrazol-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: Organocatalyst-mediated enantioselective intramolecular aldol reaction featuring the rare combination of aldehyde as nucleophile and ketone as electrophile.

Journal: The Journal of organic chemistry 20070817

Title: Dual mechanism of zinc-proline catalyzed aldol reactions in water.

Journal: Chemical communications (Cambridge, England) 20060414

Title: Direct asymmetric organocatalytic Michael reactions of alpha,alpha-disubstituted aldehydes with beta-nitrostyrenes for the synthesis of quaternary carbon-containing products.

Journal: Organic letters 20040722

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Tags:195311-28-5 Molecular Formula|195311-28-5 MDL|195311-28-5 SMILES|195311-28-5 1-(Pyrrolidin-2-ylmethyl)pyrrolidine