Title: Nurr1 and PPARγ protect PC12 cells against MPP(+) toxicity: involvement of selective genes, anti-inflammatory, ROS generation, and antimitochondrial impairment.
Journal: Molecular and cellular biochemistry 20160901
Title: Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds.
Journal: Journal of medicinal chemistry 20120614
Title: Angiogenic response of advanced glycation end products (AGEs) involves PPARgamma.
Journal: Indian journal of biochemistry & biophysics 20120201
Title: Bezafibrate restores the inhibition of FSH-induced follicular development and steroidogenesis by tumor necrosis factor-alpha through peroxisome proliferator-activated receptor-gamma pathway in an in vitro mouse preantral follicle culture.
Journal: Biology of reproduction 20111101
Title: Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.
Journal: Environmental health perspectives 20110801
Title: Nox2-derived ROS in PPARγ signaling and cell-cycle progression of lung alveolar epithelial cells.
Journal: Free radical biology & medicine 20110801
Title: Ameliorative effects of GW1929, a nonthiazolidinedione PPARγ agonist, on inflammation and apoptosis in focal cerebral ischemic-reperfusion injury.
Journal: Current neurovascular research 20110801
Title: PPARγ-dependent peptidoglycan recognition protein 3 (PGlyRP3) expression regulates proinflammatory cytokines by microbial and dietary fatty acids.
Journal: Immunobiology 20110601
Title: Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production.
Journal: Journal of molecular endocrinology 20110201
Title: GW1929: a nonthiazolidinedione PPARγ agonist, ameliorates neurological damage in global cerebral ischemic-reperfusion injury through reduction in inflammation and DNA fragmentation.
Journal: Behavioural brain research 20110120
Title: Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscle.
Journal: British journal of pharmacology 20110101
Title: PPARγ activates ABCA1 gene transcription but reduces the level of ABCA1 protein in HepG2 cells.
Journal: Biochemical and biophysical research communications 20101119
Title: Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.
Journal: Molecular pharmacology 20100901
Title: PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.
Journal: Cardiovascular research 20100501
Title: Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators.
Journal: Bioorganic & medicinal chemistry letters 20100215
Title: A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
Title: DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer.
Journal: Journal of the National Cancer Institute 20100106
Title: Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia.
Journal: Brain research 20091211
Title: Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.
Journal: Atherosclerosis 20091201
Title: 7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
Journal: Journal of medicinal chemistry 20091112
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Role of G protein-coupled receptor kinase-2 in peroxisome proliferator-activated receptor gamma-mediated modulation of blood pressure and renal vascular reactivity in SHR.
Journal: American journal of nephrology 20090901
Title: Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.
Journal: Cardiovascular diabetology 20090101
Title: In vivo imaging reveals selective peroxisome proliferator activated receptor modulator activity of the synthetic ligand 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886).
Journal: Molecular pharmacology 20080501
Title: Telmisartan inhibits CD4-positive lymphocyte migration independent of the angiotensin type 1 receptor via peroxisome proliferator-activated receptor-gamma.
Journal: Hypertension (Dallas, Tex. : 1979) 20080201
Title: Effects of the PPARgamma agonist GW1929 on muscle wasting in tumour-bearing mice.
Journal: Oncology reports 20080101
Title: Characterization of Tusc5, an adipocyte gene co-expressed in peripheral neurons.
Journal: Molecular and cellular endocrinology 20070930
Title: PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties.
Journal: Cell metabolism 20070801
Title: Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.
Journal: Protein science : a publication of the Protein Society 20060801
Title: Peroxisome proliferator-activated receptor-gamma ligands inhibit alpha5 integrin gene transcription in non-small cell lung carcinoma cells.
Journal: American journal of respiratory cell and molecular biology 20050401
Title: Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries.
Journal: Pharmacology 20050101
Title: Pituitary resistin gene expression is upregulated in vitro and in vivo by dexamethasone but is unaffected by rosiglitazone.
Journal: Neuroendocrinology 20050101
Title: Tumor necrosis factor-alpha inhibits peroxisome proliferator-activated receptor gamma activity at a posttranslational level in hepatic stellate cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040501
Title: Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030715
Title: Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells.
Journal: Fertility and sterility 20030301
Title: Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929.
Journal: Experimental cell research 20020715
Title: Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
Journal: Molecular endocrinology (Baltimore, Md.) 20011001
Title: Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.
Journal: Cytometry 20010801
Title: Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
Journal: The Journal of biological chemistry 20010713
Title: Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues.
Journal: Endocrinology 20010301
Title: The PPARs: from orphan receptors to drug discovery.
Journal: Journal of medicinal chemistry 20000224
Title: A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
Journal: Diabetes 19990701
Title: N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.
Journal: Journal of medicinal chemistry 19981203
Title: Brown KK, et al. A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat. Diabetes. 1999 Jul;48(7):1415-24.
Title: Wojtowicz AK, et al. PPAR-γ agonist GW1929 but not antagonist GW9662 reduces TBBPA-induced neurotoxicity in primary neocortical cells. Neurotox Res. 2014 Apr;25(3):311-22.
