Title: Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus.
Journal: Science (New York, N.Y.) 20160527
Title: Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders.
Journal: Journal of medicinal chemistry 20151210
Title: Anti-atherogenic effects of the combination therapy with olmesartan and azelnidipine in diabetic apolipoprotein E-deficient mice.
Journal: The Tohoku journal of experimental medicine 20121201
Title: Basal and stress-induced Hsp70 are modulated by ataxin-3.
Journal: Cell stress & chaperones 20121101
Title: Angiotensin II receptor blocker-based therapy in Japanese elderly, high-risk, hypertensive patients.
Journal: The American journal of medicine 20121001
Title: The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
Journal: Diabetes & vascular disease research 20121001
Title: Getting a sense for signals: regulation of the plant iron deficiency response.
Journal: Biochimica et biophysica acta 20120901
Title: The zinc homeostasis network of land plants.
Journal: Biochimica et biophysica acta 20120901
Title: Production of N-acetyl cis-4-hydroxy-L-proline by the yeast N-acetyltransferase Mpr1.
Journal: Journal of bioscience and bioengineering 20120801
Title: Association of changes in ambulatory arterial stiffness index and pulse wave velocity during antihypertensive treatment: the J-CORE study.
Journal: American journal of hypertension 20120801
Title: STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.
Journal: Molecular cell 20120713
Title: A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast.
Journal: The Journal of biological chemistry 20120706
Title: Azelnidipine, unique calcium channel blocker could prevent stress-induced cardiac dysfunction like α·β blocker.
Journal: Journal of cardiology 20120701
Title: Senescence-induced iron mobilization in source leaves of barley (Hordeum vulgare) plants.
Journal: The New phytologist 20120701
Title: Combined effect of angiotensin II receptor blocker and either a calcium channel blocker or diuretic on day-by-day variability of home blood pressure: the Japan Combined Treatment With Olmesartan and a Calcium-Channel Blocker Versus Olmesartan and Diuretics Randomized Efficacy Study.
Journal: Hypertension (Dallas, Tex. : 1979) 20120601
Title: Calcium antagonist added to angiotensin receptor blocker: a recipe for reducing blood pressure variability?: evidence from day-by-day home blood pressure monitoring.
Journal: Hypertension (Dallas, Tex. : 1979) 20120601
Title: Nicotianamine functions in the Phloem-based transport of iron to sink organs, in pollen development and pollen tube growth in Arabidopsis.
Journal: The Plant cell 20120601
Title: Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis.
Journal: Plant physiology 20120401
Title: Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation.
Journal: The Journal of biological chemistry 20120309
Title: Mechanistic study on degradation of azelnidipine solution under radical initiator-based oxidative conditions.
Journal: Journal of pharmaceutical and biomedical analysis 20120305
Title: Azelnidipine attenuates glomerular damage in Dahl salt-sensitive rats by suppressing sympathetic nerve activity.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120301
Title: Enhancement of anthraquinone production in Morinda citrifolia cell suspension cultures after stimulation of the proline cycle with two proline analogs.
Journal: Biotechnology letters 20120301
Title: Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence.
Journal: British journal of pharmacology 20120201
Title: Identification of Zn-nicotianamine and Fe-2'-Deoxymugineic acid in the phloem sap from rice plants (Oryza sativa L.).
Journal: Plant & cell physiology 20120201
Title: Nicotianamine in zinc and iron homeostasis.
Journal: The Plant cell 20120201
Title: Elevated nicotianamine levels in Arabidopsis halleri roots play a key role in zinc hyperaccumulation.
Journal: The Plant cell 20120201
Title: Vacuolar nicotianamine has critical and distinct roles under iron deficiency and for zinc sequestration in Arabidopsis.
Journal: The Plant cell 20120201
Title: Analysis of iron-phytosiderophore complexes in soil related samples: LC-ESI-MS/MS versus CE-MS.
Journal: Electrophoresis 20120201
Title: Effects of ring contraction on the conformational preferences of α-substituted proline analogs.
Journal: Biopolymers 20120101
Title: Olmesartan medoxomil and azelnidipine therapy in patients with hypertension and chronic kidney disease in Japan.
Journal: Journal of nephrology 20120101
Title: Combination therapy of olmesartan and azelnidipine inhibits sympathetic activity associated with reducing oxidative stress in the brain of hypertensive rats.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101
Title: Long-term effects of calcium antagonists on augmentation index in hypertensive patients with chronic kidney disease: a randomized controlled study.
Journal: American journal of nephrology 20120101
Title: Solid state characterizations and analysis of stability in azelnidipine polymorphs.
Journal: Chemical & pharmaceutical bulletin 20120101
Title: Azelnidipine inhibits Msx2-dependent osteogenic differentiation and matrix mineralization of vascular smooth muscle cells.
Journal: International heart journal 20120101
Title: Genetic and biochemical approaches for studying the yellow stripe-like transporter family in plants.
Journal: Current topics in membranes 20120101
Title: Bio-available zinc in rice seeds is increased by activation tagging of nicotianamine synthase.
Journal: Plant biotechnology journal 20111001
Title: Synthesis, antiproliferative activity and DNA binding study of mixed ammine/cyclohexylamine platinum(II) complexes with 1-(substituted benzyl) azetidine-3, 3-dicarboxylates.
Journal: European journal of medicinal chemistry 20111001
Title: Regulation of chaperone gene expression by heat shock transcription factor in Saccharomyces cerevisiae: importance in normal cell growth, stress resistance, and longevity.
Journal: FEBS letters 20110902
Title: Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: implications for protein misfolding and TDP-43 regulation.
Journal: Journal of neuroscience research 20110901
Title: The binding of aluminum to mugineic acid and related compounds as studied by potentiometric titration.
Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20110801
Title: Design and rationale of Japanese evaluation between Formula of Azelnidipine and amlodipine add on olmesartan to Get antialbuminuric effect study (J-FLAG) : evaluation of the antialbuminuric effects between calcium channel blocker with sympatholytic action in hypertensive patients with diabetes and albuminuria.
Journal: Cardiovascular drugs and therapy 20110801
Title: Additive antioxidative effects of azelnidipine on angiotensin receptor blocker olmesartan treatment for type 2 diabetic patients with albuminuria.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110801
Title: L-/T-type Ca channel blockers for kidney protection: ready for sophisticated use of Ca channel blockers.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110801
Title: Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast.
Journal: PLoS genetics 20110801
Title: Azelnidipine, a new calcium channel blocker, promotes skin wound healing in diabetic rats.
Journal: The Journal of surgical research 20110701
Title: A novel transcription factor, ERD15 (Early Responsive to Dehydration 15), connects endoplasmic reticulum stress with an osmotic stress-induced cell death signal.
Journal: The Journal of biological chemistry 20110603
Title: Calcium channel blocker inhibition of AGE and RAGE axis limits renal injury in nondiabetic patients with stage I or II chronic kidney disease.
Journal: Clinical cardiology 20110601
Title: The role of transition metal homeostasis in plant seed development.
Journal: Current opinion in plant biology 20110601
Title: Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis.
Journal: The Plant cell 20110501
Title: Urinary albumin excretion during angiotensin II receptor blockade: comparison of combination treatment with a diuretic or a calcium-channel blocker.
Journal: American journal of hypertension 20110401
Title: Reduction of albuminuria with antihypertensive treatment: is more always better?
Journal: American journal of hypertension 20110401
Title: Association between aldosterone induced by antihypertensive medication and arterial stiffness reduction: the J-CORE study.
Journal: Atherosclerosis 20110301
Title: Phytosiderophore efflux transporters are crucial for iron acquisition in graminaceous plants.
Journal: The Journal of biological chemistry 20110218
Title: Co-treatment with azelinidipine and olmesartan inhibits advanced glycation end products (AGEs) elicited down-regulation of adiponectin mRNA levels in cultured adipocytes partly via its anti-oxidative property.
Journal: International journal of cardiology 20110121
Title: N-aminoazetidinecarboxylic acid: direct access to a small-ring hydrazino acid.
Journal: The Journal of organic chemistry 20110121
Title: Use of recombinantly produced 15N3-labelled nicotianamine for fast and sensitive stable isotope dilution ultra-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20110101
Title: Transcriptome profiling of the rice blast fungus during invasive plant infection and in vitro stresses.
Journal: BMC genomics 20110101
Title: Comparison of combination therapy of olmesartan plus azelnidipine or hydrochlorothiazide on renal and vascular damage in SHR/NDmcr-cp rats.
Journal: Kidney & blood pressure research 20110101
Title: Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo University (ALPS-J).
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Comparative effects of azelnidipine and amlodipine on myocardial function and mortality after ischemia/reperfusion in dogs.
Journal: Journal of pharmacological sciences 20110101
Title: Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1.
Journal: BMC biology 20110101
Title: Intravascular ultrasound parameters in non-inferiority trial.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation.
Journal: PloS one 20110101
Title: Effects of Azelnidipine plus OlmesaRTAn versus amlodipine plus olmesartan on central blood pressure and left ventricular mass index: the AORTA study.
Journal: Vascular health and risk management 20110101
Title: Functional compounds in fermented buckwheat sprouts.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: Effects of calcium channel blockers on glucose tolerance, inflammatory state, and circulating progenitor cells in non-diabetic patients with essential hypertension: a comparative study between azelnidipine and amlodipine on glucose tolerance and endothelial function--a crossover trial (AGENT).
Journal: Cardiovascular diabetology 20110101
Title: Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis.
Journal: Cardiovascular diabetology 20110101
Title: Mugineic acid derivatives as molecular probes for the mechanistic elucidation of iron acquisition in barley.
Journal: Angewandte Chemie (International ed. in English) 20101217
Title: Azelnidipine-induced chyloperitoneum in a patient with microscopic polyangiitis.
Journal: Clinical and experimental nephrology 20101001
Title: A 9 bp cis-element in the promoters of class I small heat shock protein genes on chromosome 3 in rice mediates L-azetidine-2-carboxylic acid and heat shock responses.
Journal: Journal of experimental botany 20101001
Title: Successful reproduction requires the function of Arabidopsis Yellow Stripe-Like1 and Yellow Stripe-Like3 metal-nicotianamine transporters in both vegetative and reproductive structures.
Journal: Plant physiology 20100901
Title: Plant Physiology. On the inside.
Journal: Plant physiology 20100901
Title: In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: The application of the yeast N-acetyltransferase MPR1 gene and the proline analogue L-azetidine-2-carboxylic acid as a selectable marker system for plant transformation.
Journal: Journal of experimental botany 20100601
Title: Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients.
Journal: The American journal of the medical sciences 20100501
Title: [Heavy metal absorption, transportation and accumulation mechanisms in hyperaccumulator Thlaspi caerulescens].
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20100501
Title: Effects of combination olmesartan medoxomil plus azelnidipine versus monotherapy with either agent on 24-hour ambulatory blood pressure and pulse rate in Japanese patients with essential hypertension: additional results from the REZALT study.
Journal: Clinical therapeutics 20100501
Title: Misincorporation of the proline homologue Aze (azetidine-2-carboxylic acid) into recombinant myelin basic protein.
Journal: Phytochemistry 20100401
Title: Response to zinc deficiency of two rice lines with contrasting tolerance is determined by root growth maintenance and organic acid exudation rates, and not by zinc-transporter activity.
Journal: The New phytologist 20100401
Title: Combination therapy with olmesartan and azelnidipine improves EDHF-mediated responses in diabetic apolipoprotein E-deficient mice.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100401
Title: Complexation of metals by phytosiderophores revealed by CE-ESI-MS and CE-ICP-MS.
Journal: Electrophoresis 20100401
Title: Toward mechanistic elucidation of iron acquisition in barley: efficient synthesis of mugineic acids and their transport activities.
Journal: Chemical record (New York, N.Y.) 20100401
Title: Cardiovascular effects of azelnidipine in comparison with those of amlodipine assessed in the halothane-anaesthetized dog.
Journal: Basic & clinical pharmacology & toxicology 20100201
Title: Heterologous expression of Saccharomyces cerevisiae MPR1 gene confers tolerance to ethanol and L: -azetidine-2-carboxylic acid in Hansenula polymorpha.
Journal: Journal of industrial microbiology & biotechnology 20100201
Title: [Enantiomeric separation of azelnidipine by high performance liquid chromatography with chiral stationary phase].
Journal: Se pu = Chinese journal of chromatography 20100201
Title: Azelnidipine, a long-acting calcium channel blocker, could control hypertension without decreasing cerebral blood flow in post-ischemic stroke patients. A 123I-IMP SPECT follow-up study.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20100101
Title: [Calcium antagonists: current and future applications based on new evidence. Calcium channel blockers and autonomic nervous system].
Journal: Clinical calcium 20100101
Title: Beneficial effect of combination therapy comprising angiotensin II receptor blocker plus calcium channel blocker on plasma adiponectin levels.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101
Title: Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.
Journal: Internal medicine (Tokyo, Japan) 20100101
Title: Anti-inflammatory properties of azelnidipine, a dihydropyridine-based calcium channel blocker.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101
Title: Nicotianamine, a novel enhancer of rice iron bioavailability to humans.
Journal: PloS one 20100101
Title: Cytokine reducing effect of azelnidipine in human peripheral blood mononuclear cells.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Studies on the mechanism of antihypertensive action by nicotianamine.
Journal: Journal of nutritional science and vitaminology 20100101
Title: Azelnidipine and amlodipine: a comparison of their effects and safety in a randomized double-blinded clinical trial in Chinese essential hypertensive patients.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101
Title: Nicotianamine forms complexes with Zn(II) in vivo.
Journal: Metallomics : integrated biometal science 20100101
Title: Azelnidipine protects myocardium in hyperglycemia-induced cardiac damage.
Journal: Cardiovascular diabetology 20100101
Title: Azelnidipine exerts renoprotective effects by improvement of renal microcirculation in angiotensin II infusion rats.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
Title: A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension: the REZALT study.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091201
Title: Angiotensin-II receptor antagonist combined with calcium channel blocker or diuretic for essential hypertension.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091101
Title: MPR1 as a novel selection marker in Saccharomyces cerevisiae.
Journal: Yeast (Chichester, England) 20091101
Title: A highly sensitive, quick and simple quantification method for nicotianamine and 2'-deoxymugineic acid from minimum samples using LC/ESI-TOF-MS achieves functional analysis of these components in plants.
Journal: Plant & cell physiology 20091101
Title: Differential effects between a calcium channel blocker and a diuretic when used in combination with angiotensin II receptor blocker on central aortic pressure in hypertensive patients.
Journal: Hypertension (Dallas, Tex. : 1979) 20091001
Title: Central blood pressure under angiotensin and calcium channel blockade.
Journal: Hypertension (Dallas, Tex. : 1979) 20091001
Title: Impact of azelnidipine treatment on left ventricular diastolic performance in patients with hypertension and mild diastolic dysfunction: multi-center study with echocardiography.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091001
Title: Combination of chronic exercise and antihypertensive therapy enhances renoprotective effects in rats with renal ablation.
Journal: American journal of hypertension 20091001
Title: Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo university (ALPS-J).
Journal: Cardiovascular drugs and therapy 20091001
Title: Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats.
Journal: Journal of hypertension 20090901
Title: Highly efficient and enantioselective biotransformations of racemic azetidine-2-carbonitriles and their synthetic applications.
Journal: The Journal of organic chemistry 20090821
Title: OsYSL18 is a rice iron(III)-deoxymugineic acid transporter specifically expressed in reproductive organs and phloem of lamina joints.
Journal: Plant molecular biology 20090801
Title: Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers.
Journal: Journal of cardiovascular pharmacology 20090701
Title: Engineering of the yeast antioxidant enzyme Mpr1 for enhanced activity and stability.
Journal: Biotechnology and bioengineering 20090601
Title: Combination use of immune complexes and a Ca2(+) channel blocker azelnidipine enhances interleukin-12 p40 secretion without T helper type 17 cytokine secretion in human monocyte-derived dendritic cells.
Journal: Clinical and experimental immunology 20090601
Title: The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses.
Journal: Plant physiology 20090501
Title: The heat-induced gamma-H2AX response does not play a role in hyperthermic cell killing.
Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20090501
Title: Therapeutic strategy for ischemic stroke.
Journal: Neurochemical research 20090401
Title: Chronotropic effects of azelnidipine, a slow- and long-acting dihydropyridine-type calcium channel blocker, in anesthetized dogs: a comparison with amlodipine.
Journal: Journal of cardiovascular pharmacology 20090401
Title: Time course analysis of gene expression over 24 hours in Fe-deficient barley roots.
Journal: Plant molecular biology 20090301
Title: Azelnidipine inhibits aldosterone synthesis and secretion in human adrenocortical cell line NCI-H295R.
Journal: European journal of pharmacology 20090301
Title: Increased sensitivity to iron deficiency in Arabidopsis thaliana overaccumulating nicotianamine.
Journal: Journal of experimental botany 20090301
Title: Rice OsYSL15 is an iron-regulated iron(III)-deoxymugineic acid transporter expressed in the roots and is essential for iron uptake in early growth of the seedlings.
Journal: The Journal of biological chemistry 20090206
Title: Engineering of the yeast ubiquitin ligase Rsp5: isolation of a new variant that induces constitutive inactivation of the general amino acid permease Gap1.
Journal: FEMS yeast research 20090201
Title: Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists.
Journal: American journal of hypertension 20090201
Title: The cytosolic protein response as a subcomponent of the wider heat shock response in Arabidopsis.
Journal: The Plant cell 20090201
Title: Time-course study and effects of drying method on concentrations of gamma-aminobutyric acid, flavonoids, anthocyanin, and 2''-hydroxynicotianamine in leaves of buckwheats.
Journal: Journal of agricultural and food chemistry 20090114
Title: Genetically engineered rice containing larger amounts of nicotianamine to enhance the antihypertensive effect.
Journal: Plant biotechnology journal 20090101
Title: Metal movement within the plant: contribution of nicotianamine and yellow stripe 1-like transporters.
Journal: Annals of botany 20090101
Title: Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors.
Journal: ChemMedChem 20090101
Title: Nicotianamine and histidine/proline are, respectively, the most important copper chelators in xylem sap of Brassica carinata under conditions of copper deficiency and excess.
Journal: Journal of experimental botany 20090101
Title: Azetidine-2-carboxylic acid in the food chain.
Journal: Phytochemistry 20090101
Title: Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi.
Journal: PloS one 20090101
Title: Synthesis and biological activity of nicotianamine and analogues.
Journal: Advances in experimental medicine and biology 20090101
Title: Comparative effects of olmesartan and azelnidipine on atrial structural remodeling in spontaneously hypertensive rats.
Journal: Pharmacology 20090101
Title: Gene and stem cell therapy in ischemic stroke.
Journal: Cell transplantation 20090101
Title: Comparative pharmacodynamics of olmesartan and azelnidipine in patients with hypertension: a population pharmacokinetic/pharmacodynamic analysis.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: Beneficial effects of combination therapy with olmesartan and azelnidipine in murine polycystic kidneys.
Journal: Kidney & blood pressure research 20090101
Title: The discovery of BMAA, and examples of biomagnification and protein incorporation involving other non-protein amino acids.
Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101
Title: Azelnidipine decreases plasma matrix metalloproteinase-9 levels after endovascular abdominal aortic aneurysm repair.
Journal: The Kurume medical journal 20090101
Title: Enhanced pulsatile pressure accelerates vascular smooth muscle migration: implications for atherogenesis of hypertension.
Journal: Cardiovascular research 20081201
Title: Embryoid body morphology influences diffusive transport of inductive biochemicals: a strategy for stem cell differentiation.
Journal: Biomaterials 20081201
Title: Renoprotective effect of azelnidipine in rats.
Journal: Biological & pharmaceutical bulletin 20081201
Title: Azelnidipine decreases sympathetic nerve activity via antioxidant effect in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats.
Journal: Journal of cardiovascular pharmacology 20081201
Title: Hemodynamic influences of azelnidipine, a novel calcium channel blocker, on cerebral circulation in hypertensive patients with ischemic white matter lesions.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20081201
Title: Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis.
Journal: Journal of neuropathology and experimental neurology 20081101
Title: A novel unifying hypothesis of multiple sclerosis.
Journal: Journal of neuropathology and experimental neurology 20081101
Title: Additional renoprotective effects of azelnidipine combined with angiotensin receptor blockers in patients with diabetic nephropathy.
Journal: Clinical nephrology 20081101
Title: Investigation of ascorbate-mediated iron release from ferric phytosiderophores in the presence of nicotianamine.
Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20081001
Title: Determination of azelnidipine by LC-ESI-MS and its application to a pharmacokinetic study in healthy Chinese volunteers.
Journal: Die Pharmazie 20080801
Title: In half of hypertensive diabetics, co-administration of a calcium channel blocker and an angiotensin-converting enzyme inhibitor achieved a target blood pressure of <130/80 mmHg: the azelnidipine and temocapril in hypertensive patients with type 2 diabetes (ATTEST) study.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080801
Title: In vivo imaging of renal redox status during azelnidipine treatment.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080801
Title: Identification of amino acid residues essential for the yeast N-acetyltransferase Mpr1 activity by site-directed mutagenesis.
Journal: FEMS yeast research 20080601
Title: Combination therapy with renin-angiotensin system inhibitors and the calcium channel blocker azelnidipine decreases plasma inflammatory markers and urinary oxidative stress markers in patients with diabetic nephropathy.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080601
Title: Formation of metal-nicotianamine complexes as affected by pH, ligand exchange with citrate and metal exchange. A study by electrospray ionization time-of-flight mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20080501
Title: Deoxymugineic acid increases Zn translocation in Zn-deficient rice plants.
Journal: Plant molecular biology 20080401
Title: Effects of azelnidipine on the autonomic functions and its influence on arterial stiffness and endothelial functions.
Journal: Journal of cardiology 20080401
Title: Azetidine-derived amino acids versus proline derivatives. alternative trends in reverse turn induction.
Journal: The Journal of organic chemistry 20080307
Title: Spectroscopic studies on the interaction of azelnidipine with bovine serum albumin.
Journal: International journal of pharmaceutics 20080303
Title: Effects of antihypertensive drugs and exercise training on insulin sensitivity in spontaneously hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080301
Title: Distribution of L-azetidine-2-carboxylate N-acetyltransferase in yeast.
Journal: Bioscience, biotechnology, and biochemistry 20080201
Title: Azelnidipine has anti-atherosclerotic effects independent of its blood pressure-lowering actions in monkeys and mice.
Journal: Atherosclerosis 20080101
Title: Isotopomer-based metabolomic analysis by NMR and mass spectrometry.
Journal: Methods in cell biology 20080101
Title: A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery.
Journal: BMC cell biology 20080101
Title: Calcium channel blocker, azelnidipine, reduces lipid hydroperoxides in patients with type 2 diabetes independent of blood pressure.
Journal: Endocrine journal 20071201
Title: Mutation in nicotianamine aminotransferase stimulated the Fe(II) acquisition system and led to iron accumulation in rice.
Journal: Plant physiology 20071201
Title: Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats.
Journal: Brain research 20071024
Title: CE of phytosiderophores and related metal species in plants.
Journal: Electrophoresis 20071001
Title: Hsp70-GlcNAc-binding activity is released by stress, proteasome inhibition, and protein misfolding.
Journal: Biochemical and biophysical research communications 20070921
Title: The rice bHLH protein OsIRO2 is an essential regulator of the genes involved in Fe uptake under Fe-deficient conditions.
Journal: The Plant journal : for cell and molecular biology 20070801
Title: Nicotianamine preferentially inhibits Angiotensin I-converting enzyme.
Journal: Journal of nutritional science and vitaminology 20070801
Title: Antioxidative effects of azelnidipine on mesangial cell proliferation induced by highly concentrated insulin.
Journal: European journal of pharmacology 20070719
Title: Enantioselective determination of azelnidipine in human plasma using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
Title: Iron utilization and metabolism in plants.
Journal: Current opinion in plant biology 20070601
Title: Azelnidipine reduces urinary protein excretion and urinary liver-type fatty acid binding protein in patients with hypertensive chronic kidney disease.
Journal: The American journal of the medical sciences 20070601
Title: Effects of new calcium channel blocker, azelnidipine, and amlodipine on baroreflex sensitivity and ambulatory blood pressure.
Journal: Journal of cardiovascular pharmacology 20070601
Title: Effect of benidipine on simvastatin metabolism in human liver microsomes.
Journal: Drug metabolism and pharmacokinetics 20070601
Title: The expression of iron homeostasis-related genes during rice germination.
Journal: Plant molecular biology 20070501
Title: [Responses to iron-deficiency stress by graminaceous plants].
Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20070501
Title: The long-acting Ca2+-channel blocker azelnidipine prevents left ventricular remodeling after myocardial infarction.
Journal: Journal of pharmacological sciences 20070401
Title: Azelnidipine attenuates cardiovascular and sympathetic responses to air-jet stress in genetically hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20070401
Title: Highly sensitive quantitative analysis of nicotianamine using LC/ESI-TOF-MS with an internal standard.
Journal: Bioscience, biotechnology, and biochemistry 20070201
Title: Azelnidipine inhibits H2O2-induced cell death in neonatal rat cardiomyocytes.
Journal: Cardiovascular drugs and therapy 20070201
Title: Determination of azelnidipine in human plasma by liquid chromatography-electrospray ionization-mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20070117
Title: TcYSL3, a member of the YSL gene family from the hyper-accumulator Thlaspi caerulescens, encodes a nicotianamine-Ni/Fe transporter.
Journal: The Plant journal : for cell and molecular biology 20070101
Title: Long-acting calcium channel blocker, azelnidipine, increases endothelial nitric oxide synthase in the brain and inhibits sympathetic nerve activity.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20070101
Title: Effects of calcium channel blocker azelnidipine on experimental abdominal aortic aneurysms.
Journal: Surgery today 20070101
Title: A practical synthesis of the phytosiderophore 2'-deoxymugineic acid: a key to the mechanistic study of iron acquisition by graminaceous plants.
Journal: Angewandte Chemie (International ed. in English) 20070101
Title: Relationships of nicotianamine and other amino acids with nickel, zinc and iron in Thlaspi hyperaccumulators.
Journal: The New phytologist 20070101
Title: Clinical study with azelnidipine in patients with essential hypertension. Antiarteriosclerotic and cardiac hypertrophy-inhibitory effects and influence on autonomic nervous activity.
Journal: Arzneimittel-Forschung 20070101
Title: SDF-1-induced adhesion of monocytes to vascular endothelium is modulated by azelnidipine via protein kinase C inhibition.
Journal: European journal of pharmacology 20061215
Title: Calcium channel blocker azelnidipine reduces glucose intolerance in diabetic mice via different mechanism than angiotensin receptor blocker olmesartan.
Journal: The Journal of pharmacology and experimental therapeutics 20061201
Title: Tilting-induced decrease in systolic blood pressure in bedridden hypertensive elderly inpatients: effects of azelnidipine.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20061201
Title: Simultaneous determination of azelnidipine and two metabolites in human plasma using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121
Title: The actions of azelnidipine, a dihydropyridine-derivative Ca antagonist, on voltage-dependent Ba2+ currents in guinea-pig vascular smooth muscle.
Journal: British journal of pharmacology 20061101
Title: Cloning and characterization of deoxymugineic acid synthase genes from graminaceous plants.
Journal: The Journal of biological chemistry 20061027
Title: Anion exchange liquid chromatography--inductively coupled plasma-mass spectrometry detection of the Co2+, Cu2+, Fe3+ and Ni2+ complexes of mugineic and deoxymugineic acid.
Journal: Journal of chromatography. A 20061006
Title: The calcium-channel blocker, azelnidipine, enhances the inhibitory action of AT1 receptor blockade on ischemic brain damage.
Journal: Journal of hypertension 20061001
Title: Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
Journal: Journal of hypertension 20061001
Title: Biosynthesis and secretion of mugineic acid family phytosiderophores in zinc-deficient barley.
Journal: The Plant journal : for cell and molecular biology 20061001
Title: Azelnidipine down-regulates renal angiotensin-converting enzyme and mineralocorticoid receptor mRNA in diabetic hypertensive rats.
Journal: Journal of pharmacological sciences 20061001
Title: Efficacy of azelnidipine on home blood pressure and pulse rate in patients with essential hypertension: comparison with amlodipine.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20061001
Title: Azelnidipine, a new calcium channel blocker, inhibits endothelial inflammatory response by reducing intracellular levels of reactive oxygen species.
Journal: European journal of pharmacology 20060928
Title: A third-generation, long-acting, dihydropyridine calcium antagonist, azelnidipine, attenuates stent-associated neointimal formation in non-human primates.
Journal: Journal of hypertension 20060901
Title: S-Adenosyl-L-methionine: beyond the universal methyl group donor.
Journal: Phytochemistry 20060801
Title: [Novel actions of calcium channel blockers].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060801
Title: [Study on the structure activity relationship of a phytosiderophore, mugineic acid].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060701
Title: Metabolic engineering of Saccharomyces cerevisiae producing nicotianamine: potential for industrial biosynthesis of a novel antihypertensive substrate.
Journal: Bioscience, biotechnology, and biochemistry 20060601
Title: Genetically modified cyanobacterium Nostoc muscorum overproducing proline in response to salinity and osmotic stresses.
Journal: Journal of biosciences 20060601
Title: The transition metal chelator nicotianamine is synthesized by filamentous fungi.
Journal: FEBS letters 20060529
Title: Azetidine-2-carboxylic acid in garden beets (Beta vulgaris).
Journal: Phytochemistry 20060501
Title: Up-regulation of the clusterin gene after proteotoxic stress: implication of HSF1-HSF2 heterocomplexes.
Journal: The Biochemical journal 20060401
Title: The special five-membered ring of proline: An experimental and theoretical investigation of alkali metal cation interactions with proline and its four- and six-membered ring analogues.
Journal: The journal of physical chemistry. A 20060323
Title: Effects of calcium channel blockade on angiotensin II-induced peritubular ischemia in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: An angiotensin-I converting enzyme inhibitor from buckwheat (Fagopyrum esculentum Moench) flour.
Journal: Phytochemistry 20060301
Title: Comparative effects of azelnidipine and other Ca2+-channel blockers on the induction of inducible nitric oxide synthase in vascular smooth muscle cells.
Journal: Journal of cardiovascular pharmacology 20060201
Title: Distinct yet linked: chaperone networks in the eukaryotic cytosol.
Journal: Genome biology 20060101
Title: Investigation of 1,3-dipolar cycloaddition reactions of unsaturated nitrones in ionic liquids.
Journal: Nucleosides, nucleotides & nucleic acids 20060101
Title: The newly developed calcium antagonist, azelnidipine, increases drain volume in continuous ambulatory peritoneal dialysis patients.
Journal: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20060101
Title: Expression of the Saccharomyces cerevisiae MPR1 gene encoding N-acetyltransferase in Zygosaccharomyces rouxii confers resistance to L-azetidine-2-carboxylate.
Journal: Folia microbiologica 20060101
Title: Root-to-shoot long-distance circulation of nicotianamine and nicotianamine-nickel chelates in the metal hyperaccumulator Thlaspi caerulescens.
Journal: Journal of experimental botany 20060101
Title: Azelnidipine, a new long-acting calcium-channel blocker, inhibits tumour necrosis factor-alpha-induced monocyte chemoattractant protein-1 expression in endothelial cells.
Journal: The Journal of international medical research 20060101
Title: Protein synthesis upon acute nutrient restriction relies on proteasome function.
Journal: Science (New York, N.Y.) 20051223
Title: A loss-of-function mutation in AtYSL1 reveals its role in iron and nicotianamine seed loading.
Journal: The Plant journal : for cell and molecular biology 20051201
Title: Effects of a new calcium channel blocker, azelnidipine, on systemic hemodynamics and renal sympathetic nerve activity in spontaneously hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20051201
Title: Increased nicotianamine biosynthesis confers enhanced tolerance of high levels of metals, in particular nickel, to plants.
Journal: Plant & cell physiology 20051101
Title: Practical asymmetric preparation of azetidine-2-carboxylic acid.
Journal: The Journal of organic chemistry 20051028
Title: Efficient route to (S)-azetidine-2-carboxylic acid.
Journal: Bioscience, biotechnology, and biochemistry 20051001
Title: Nicotianamine over-accumulation confers resistance to nickel in Arabidopsis thaliana.
Journal: Transgenic research 20051001
Title: Functional effects of Japanese style fermented soy sauce (shoyu) and its components.
Journal: Journal of bioscience and bioengineering 20050901
Title: Effect of combination of calcium antagonist, azelnidipine, and AT1 receptor blocker, olmesartan, on atherosclerosis in apolipoprotein E-deficient mice.
Journal: Journal of hypertension 20050701
Title: Effect of azelnidipine on angiotensin II-mediated growth-promoting signaling in vascular smooth muscle cells.
Journal: Molecular pharmacology 20050501
Title: Differentiation of Leishmania donovani in host-free system: analysis of signal perception and response.
Journal: Molecular and biochemical parasitology 20050501
Title: Mg-dechelation activity in radish cotyledons with artificial and native substrates, Mg-chlorophyllin a and chlorophyllide a.
Journal: Plant physiology and biochemistry : PPB 20050501
Title: Stereoselective allyl amine synthesis through enantioselective addition of diethylzinc and [1,3]-chirality transfer: synthesis of lentiginosine and polyoxamic acid derivative.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20050304
Title: Amino acid-azetidine chimeras: synthesis of enantiopure 3-substituted azetidine-2-carboxylic acids.
Journal: The journal of peptide research : official journal of the American Peptide Society 20050201
Title: Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).
Journal: British journal of pharmacology 20050101
Title: Unique atheroprotective property of azelnidipine, a dihydropyridine-based calcium antagonist.
Journal: Medical hypotheses 20050101
Title: Chronic exposure to ammonia alters the modulation of phosphorylation of microtubule-associated protein 2 by metabotropic glutamate receptors 1 and 5 in cerebellar neurons in culture.
Journal: Neuroscience 20050101
Title: Renoprotective effects of azelnidipine, a dihydropyridine-based calcium antagonist in advanced glycation end product (AGE)-injected rats.
Journal: International journal of tissue reactions 20050101
Title: Azelnidipine, a dihydropyridine-based calcium antagonist, inhibits angiotensin II-induced oxidative stress generation and downregulation of pigment epithelium-derived factor mRNA levels in microvascular endothelial cells.
Journal: Drugs under experimental and clinical research 20050101
Title: Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.
Journal: The Journal of biological chemistry 20041231
Title: Azetidine-induced accumulation of class I small heat shock proteins in the soluble fraction provides thermotolerance in soybean seedlings.
Journal: Plant & cell physiology 20041201
Title: Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress.
Journal: The Journal of biological chemistry 20041126
Title: Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).
Journal: Plant molecular biology 20041101
Title: Additive beneficial effects of the combination of a calcium channel blocker and an angiotensin blocker on a hypertensive rat-heart failure model.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20041001
Title: Arabidopsis Yellow Stripe-Like2 (YSL2): a metal-regulated gene encoding a plasma membrane transporter of nicotianamine-metal complexes.
Journal: The Plant journal : for cell and molecular biology 20040801
Title: OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron and expressed in the phloem.
Journal: The Plant journal : for cell and molecular biology 20040801
Title: Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endothelial cells through its anti-oxidative properties.
Journal: Journal of cardiovascular pharmacology 20040501
Title: Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts.
Journal: Biochemical and biophysical research communications 20040430
Title: Biliary excretion of azelnidipine, a calcium antagonist, in rats.
Journal: Journal of gastroenterology and hepatology 20040401
Title: ZmYS1 functions as a proton-coupled symporter for phytosiderophore- and nicotianamine-chelated metals.
Journal: The Journal of biological chemistry 20040305
Title: Expression of a novel yeast gene that detoxifies the proline analog azetidine-2-carboxylate confers resistance during tobacco seed germination, callus and shoot formation.
Journal: Plant cell reports 20040301
Title: Calcium channel blocker azelnidipine enhances vascular protective effects of AT1 receptor blocker olmesartan.
Journal: Hypertension (Dallas, Tex. : 1979) 20040201
Title: Four permeases import proline and the toxic proline analogue azetidine-2-carboxylate into yeast.
Journal: Yeast (Chichester, England) 20040201
Title: Antioxidant effect of a new calcium antagonist, azelnidipine, in cultured human arterial endothelial cells.
Journal: The Journal of international medical research 20040101
Title: Effects of ascorbic acid and ascorbic acid 2-phosphate, a long-acting vitamin C derivative, on the proliferation and differentiation of human osteoblast-like cells.
Journal: Cell biology international 20040101
Title: [Pharmacological profiles and clinical effects of azelnidipine, a long-acting calcium channel blocker].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20031201
Title: Enantiospecific total synthesis of (-)-polyoxamic acid using 2,3-aziridino-gamma-lactone methodology.
Journal: The Journal of organic chemistry 20031128
Title: Metabotropic receptor-mediated Ca2+ signaling elevates mitochondrial Ca2+ and stimulates oxidative metabolism in hippocampal slice cultures.
Journal: Journal of neurophysiology 20030801
Title: Discovery of an extended bundle sheath in Ricinus communis L. and its role as a temporal storage compartment for the iron chelator nicotianamine.
Journal: Planta 20030701
Title: Role of nicotianamine in the intracellular delivery of metals and plant reproductive development.
Journal: The Plant cell 20030601
Title: Azelnidipine and amlodipine: a comparison of their pharmacokinetics and effects on ambulatory blood pressure.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030301
Title: Structure-activity relationships of dynorphin analogs substituted in positions 2 and 3.
Journal: Biopolymers 20030101
Title: Azelnidipine. CS 905, Calblock, RS 9054.
Journal: Drugs in R&D 20030101
Title: Characterization of novel acetyltransferases found in budding and fission yeasts that detoxify a proline analogue, azetidine-2-carboxylic acid.
Journal: Journal of biochemistry 20030101
Title: Azelnidipine.
Journal: Drugs 20030101
Title: Activation of glutamate transporters in rods inhibits presynaptic calcium currents.
Journal: Visual neuroscience 20030101
Title: Novel function of ascorbic acid as an angiostatic factor.
Journal: Angiogenesis 20030101
Title: Reduced Cd accumulation in Zea mays: a protective role for phytosiderophores?
Journal: Environmental science & technology 20021215
Title: Polymorphism of the MPR1 gene required for toxic proline analogue resistance in the Saccharomyces cerevisiae complex species.
Journal: Yeast (Chichester, England) 20021201
Title: Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20021122
Title: Asymmetric synthesis of polyhydroxy alpha-amino acids with the sulfinimine-mediated asymmetric strecker reaction: 2-amino 2-deoxy L-xylono-1,5-lactone (polyoxamic acid lactone).
Journal: The Journal of organic chemistry 20021101
Title: Proline residues at the C terminus of nascent chains induce SsrA tagging during translation termination.
Journal: The Journal of biological chemistry 20020913
Title: FRD3, a member of the multidrug and toxin efflux family, controls iron deficiency responses in Arabidopsis.
Journal: The Plant cell 20020801
Title: Revisiting the metal-binding chemistry of nicotianamine and 2'-deoxymugineic acid. Implications for iron nutrition in strategy II plants.
Journal: Plant physiology 20020801
Title: Differential expression of two stress-inducible hsp70 genes by various stressors.
Journal: Experimental & molecular medicine 20020531
Title: Combination therapy with an angiotensin-converting enzyme (ACE) inhibitor and a calcium antagonist: beyond the renoprotective effects of ACE inhibitor monotherapy in a spontaneous hypertensive rat with renal ablation.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20020501
Title: cDNA microarray analysis of gene expression during Fe-deficiency stress in barley suggests that polar transport of vesicles is implicated in phytosiderophore secretion in Fe-deficient barley roots.
Journal: The Plant journal : for cell and molecular biology 20020401
Title: A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acid.
Journal: The Journal of biological chemistry 20011109
Title: Fe homeostasis in plant cells: does nicotianamine play multiple roles in the regulation of cytoplasmic Fe concentration?
Journal: Planta 20011001
Title: Determination of phytosiderophores by anion-exchange chromatography with pulsed amperometric detection.
Journal: Journal of chromatography. A 20010914
Title: Real-time [11C]methionine translocation in barley in relation to mugineic acid phytosiderophore biosynthesis.
Journal: Planta 20010901
Title: Improving rice yields--ironing out the details.
Journal: Nature biotechnology 20010501
Title: In vivo evidence that Ids3 from Hordeum vulgare encodes a dioxygenase that converts 2'-deoxymugineic acid to mugineic acid in transgenic rice.
Journal: Planta 20010401
Title: Coinduction of two low-molecular-weight stress proteins, alpha B crystallin and HSP28, by heat or arsenite stress in human glioma cells.
Journal: Journal of biochemistry 19931101
Title: Antihypertensive effects of CS-905, a novel dihydropyridine Ca++ channel blocker.
Journal: Japanese journal of pharmacology 19890901
