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204326-43-2,MFCD01530052
Catalog No.:AA0029DA

204326-43-2 | 1H,4H-[1,2,4]Oxadiazolo[3,4-c][1,4]benzoxazin-1-one, 8-bromo-

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Purity
Availability
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1mg
≥98%
in stock  
$68.00   $47.00
- +
5mg
≥98%
in stock  
$295.00   $206.00
- +
10mg
≥98%
in stock  
$515.00   $360.00
- +
25mg
≥98%
in stock  
$1,126.00   $788.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0029DA
Chemical Name:
1H,4H-[1,2,4]Oxadiazolo[3,4-c][1,4]benzoxazin-1-one, 8-bromo-
CAS Number:
204326-43-2
Molecular Formula:
C9H5BrN2O3
Molecular Weight:
269.0516
MDL Number:
MFCD01530052
SMILES:
Brc1ccc2c(c1)n1c(CO2)noc1=O
Properties
Properties
 
Form:
Solid  
MP:
160-163°C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
333  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
XLogP3:
2  

Literature

Title: The inotropic effects of ammonia on isolated perfused rat hearts and the mechanisms involved.

Journal: The Journal of experimental biology 20111201

Title: The soluble guanylyl cyclase activator YC-1 increases intracellular cGMP and cAMP via independent mechanisms in INS-1E cells.

Journal: The Journal of pharmacology and experimental therapeutics 20110901

Title: Methodological proof of immunochemistry for specific identification of 8-nitroguanosine 3',5'-cyclic monophosphate formed in glia cells.

Journal: Nitric oxide : biology and chemistry 20110801

Title: Fluorescence dequenching makes haem-free soluble guanylate cyclase detectable in living cells.

Journal: PloS one 20110101

Title: Endothelium-derived nitric oxide inhibits the relaxation of the porcine coronary artery to natriuretic peptides by desensitizing big conductance calcium-activated potassium channels of vascular smooth muscle.

Journal: The Journal of pharmacology and experimental therapeutics 20100701

Title: The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100301

Title: Effects of carbon monoxide on trout and lamprey vessels.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090101

Title: cGMP-independent anti-tumour actions of the inhibitor of soluble guanylyl cyclase, ODQ, in prostate cancer cell lines.

Journal: British journal of pharmacology 20081101

Title: Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

Journal: Journal of medicinal chemistry 20080724

Title: Nitric oxide mediates lymphatic vessel activation via soluble guanylate cyclase alpha1beta1-impact on inflammation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201

Title: Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate.

Journal: Nature chemical biology 20071101

Title: NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes.

Journal: Cardiovascular research 20070715

Title: Up-regulation of microglial CD11b expression by nitric oxide.

Journal: The Journal of biological chemistry 20060526

Title: Nitric oxide inhibits gastric acid secretion by increasing intraparietal cell levels of cGMP in isolated human gastric glands.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20051201

Title: Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG.

Journal: Molecular human reproduction 20031201

Title: Post-transcriptional regulation of soluble guanylyl cyclase expression in rat aorta.

Journal: The Journal of biological chemistry 20030124

Title: Facilitatory role of NO in neural norepinephrine release in the rat kidney.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Comparative vasodilation of peroxynitrite and 3-morpholinosydnonimine.

Journal: Life sciences 20011005

Title: Both serotonin and a nitric-oxide donor cause chloride secretion in rat colonocytes by stimulating cGMP.

Journal: Surgery 20010801

Title: Accumulation of HIF-1alpha under the influence of nitric oxide.

Journal: Blood 20010215

Title: Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase.

Journal: British journal of pharmacology 19980101

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Tags:204326-43-2 Molecular Formula|204326-43-2 MDL|204326-43-2 SMILES|204326-43-2 1H,4H-[1,2,4]Oxadiazolo[3,4-c][1,4]benzoxazin-1-one, 8-bromo-