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2044-85-1,MFCD00037501
Catalog No.:AA0029EL

2044-85-1 | 2',7'-Dichlorofluorescein diacetate

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1g
95%
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5g
98%
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0029EL
Chemical Name:
2',7'-Dichlorofluorescein diacetate
CAS Number:
2044-85-1
Molecular Formula:
C24H14Cl2O7
Molecular Weight:
485.2698
MDL Number:
MFCD00037501
SMILES:
CC(=O)Oc1cc2Oc3cc(OC(=O)C)c(cc3C3(c2cc1Cl)OC(=O)c1c3cccc1)Cl
Properties
Computed Properties
 
Complexity:
775  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
4  
XLogP3:
4.9  

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Journal: Journal of neuroinflammation 20120101

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Title: Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells.

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Journal: Archives of oral biology 20111001

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Journal: International journal of cardiology 20110121

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Journal: Anesthesiology 20100901

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Title: Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen.

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Title: Isoliquiritigenin, a natural anti-oxidant, selectively inhibits the proliferation of prostate cancer cells.

Journal: Clinical and experimental pharmacology & physiology 20100801

Title: Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice.

Journal: Endocrinology 20100801

Title: Failure of regulation results in an amplified oxidation burst by neutrophils in children with primary nephrotic syndrome.

Journal: Clinical and experimental immunology 20100701

Title: Protective effects of N-acetylcysteine on homocysteine induced injury in chick embryos.

Journal: Frontiers in bioscience (Elite edition) 20100601

Title: Methods for detection and measurement of hydrogen peroxide inside and outside of cells.

Journal: Molecules and cells 20100601

Title: Effect of Sargassum thunbergii on ROS mediated oxidative damage and identification of polyunsaturated fatty acid components.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501

Title: Taurine chloramine induces heme oxygenase-1 expression via Nrf2 activation in murine macrophages.

Journal: International immunopharmacology 20100401

Title: S100A8 and S100A9 inhibit neutrophil oxidative metabolism in-vitro: involvement of adenosine metabolites.

Journal: Free radical research 20100401

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Journal: Analytical chemistry 20100315

Title: Bacterial clearance, heterophil function, and hematological parameters of transport-stressed turkey poults supplemented with dietary yeast extract.

Journal: Poultry science 20100301

Title: Vitamin C acts indirectly to modulate isotype switching in mouse B cells.

Journal: Anatomy & cell biology 20100301

Title: A direct relationship between aggressive behavior in the resident/intruder test and cell oxidative status in adult male mice.

Journal: European journal of pharmacology 20100210

Title: Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells.

Journal: Nutrition research and practice 20100201

Title: Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1.

Journal: Cardiovascular research 20100101

Title: Identification of ROS using oxidized DCFDA and flow-cytometry.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Determination and detection of reactive oxygen species (ROS), lipid peroxidation, and electrolyte leakage in plants.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Oxidative stress in NSC-741909-induced apoptosis of cancer cells.

Journal: Journal of translational medicine 20100101

Title: Characterization of manganese superoxide dismutase from a marine cyanobacterium Leptolyngbya valderiana BDU20041.

Journal: Saline systems 20100101

Title: Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.

Journal: PloS one 20100101

Title: The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma.

Journal: Nutrition & metabolism 20100101

Title: Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways.

Journal: Journal of neuroinflammation 20100101

Title: The expression of NADPH oxidases and production of reactive oxygen species by human lung adenocarcinoma epithelial cell line A549.

Journal: Folia biologica 20100101

Title: c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.

Journal: Molecular cancer 20100101

Title: Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells.

Journal: Journal of hematology & oncology 20100101

Title: Electrical stimulation of human embryonic stem cells: cardiac differentiation and the generation of reactive oxygen species.

Journal: Experimental cell research 20091210

Title: Effect of oestrous cycle on the oxidative burst activity of blood polymorphonuclear leucocytes in cows.

Journal: Reproduction in domestic animals = Zuchthygiene 20091201

Title: Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity.

Journal: Journal of lipid research 20091201

Title: Non-irradiated campherquinone induces DNA damage in human gingival fibroblasts.

Journal: Dental materials : official publication of the Academy of Dental Materials 20091201

Title: Effects of red grape juice polyphenols in NADPH oxidase subunit expression in human neutrophils and mononuclear blood cells.

Journal: The British journal of nutrition 20091001

Title: Cytotoxicity of Senecio in macrophages is mediated via its induction of oxidative stress.

Journal: Research in veterinary science 20090801

Title: Monitoring reactive oxygen species formation and localisation in living cells by use of the fluorescent probe CM-H(2)DCFDA and confocal laser microscopy.

Journal: Physiologia plantarum 20090801

Title: Inhibitory effects of safrole on phagocytosis, intracellular reactive oxygen species, and the activity of myeloperoxidase released by human polymorphonuclear leukocytes.

Journal: Journal of periodontology 20090801

Title: Effects of dopamine on LC3-II activation as a marker of autophagy in a neuroblastoma cell model.

Journal: Neurotoxicology 20090701

Title: Cytoprotective effects of lindenenyl acetate isolated from Lindera strychnifolia on mouse hippocampal HT22 cells.

Journal: European journal of pharmacology 20090701

Title: Isolation and identification of phlorotannins from Ecklonia stolonifera with antioxidant and anti-inflammatory properties.

Journal: Journal of agricultural and food chemistry 20090513

Title: Keratinocyte growth factor down-regulates intracellular ROS production induced by UVB.

Journal: Journal of dermatological science 20090501

Title: Swimming training prevents pentylenetetrazol-induced inhibition of Na+, K+-ATPase activity, seizures, and oxidative stress.

Journal: Epilepsia 20090401

Title: Antitumor activity of arsenic trioxide on retinoblastoma: cell differentiation and apoptosis depending on arsenic trioxide concentration.

Journal: Investigative ophthalmology & visual science 20090401

Title: Lysophosphatidylcholine induces endothelial cell injury by nitric oxide production through oxidative stress.

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20090401

Title: Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor.

Journal: Experimental & molecular medicine 20090331

Title: A method to measure total antioxidant capacity against peroxyl radicals in aquatic organisms: application to evaluate microcystins toxicity.

Journal: The Science of the total environment 20090301

Title: Increased oxidative activity in human blood neutrophils and monocytes after spinal cord injury.

Journal: Experimental neurology 20090201

Title: Phagocytosis of heat-killed Staphylococcus aureus by eosinophils: comparison with neutrophils.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20090201

Title: NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells.

Journal: The Journal of biological chemistry 20090123

Title: Lack of evidence for oxidative stress in sporadic amyotrophic lateral sclerosis fibroblasts.

Journal: Neuro-degenerative diseases 20090101

Title: Heavy metals generate reactive oxygen species in terrestrial and aquatic ciliated protozoa.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090101

Title: Necrotic cell death: From reversible mitochondrial uncoupling to irreversible lysosomal permeabilization.

Journal: Experimental cell research 20090101

Title: Genotoxicity of imidacloprid in relation to metabolic activation and composition of the commercial product.

Journal: Mutation research 20090101

Title: Comparative transcriptomic characterization of aluminum, sodium chloride, cadmium and copper rhizotoxicities in Arabidopsis thaliana.

Journal: BMC plant biology 20090101

Title: Pro370Leu mutant myocilin impairs mitochondrial functions in human trabecular meshwork cells.

Journal: Molecular vision 20090101

Title: Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models.

Journal: Molecular cancer 20090101

Title: [Glutamate induces the formation of free radicals in rat brain synaptosomes].

Journal: Biofizika 20090101

Title: Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads.

Journal: Retrovirology 20090101

Title: Per os administered refined olive oil and marine PUFA-rich oils reach the cornea: possible role on oxidative stress through caveolin-1 modulation.

Journal: Nutrition & metabolism 20090101

Title: Protective effect of clusterin on oxidative stress-induced cell death of human corneal endothelial cells.

Journal: Molecular vision 20090101

Title: Influence of ketone bodies on oxidative stress parameters in brain of developing rats in vitro.

Journal: Metabolic brain disease 20081201

Title: Toxic-dose warfarin-induced apoptosis and its enhancement by gamma ionizing radiation in leukemia K562 and HL-60 cells is not mediated by induction of oxidative stress.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20081101

Title: Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures.

Journal: Neurotoxicology 20081101

Title: Evidence that oxidative stress is linked to anxiety-related behaviour in mice.

Journal: Brain, behavior, and immunity 20081101

Title: Taurine provides antioxidant defense against NaF-induced cytotoxicity in murine hepatocytes.

Journal: Pathophysiology : the official journal of the International Society for Pathophysiology 20081001

Title: Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo.

Journal: The Journal of pharmacy and pharmacology 20081001

Title: Bisacurone inhibits adhesion of inflammatory monocytes or cancer cells to endothelial cells through down-regulation of VCAM-1 expression.

Journal: International immunopharmacology 20080901

Title: Antioxidant effects of phlorotannins isolated from Ishige okamurae in free radical mediated oxidative systems.

Journal: Journal of agricultural and food chemistry 20080827

Title: Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.

Journal: Chemico-biological interactions 20080811

Title: Retinol up-regulates the receptor for advanced glycation endproducts (RAGE) by increasing intracellular reactive species.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080801

Title: In situ detection and measurement of intracellular reactive oxygen species in single isolated mature skeletal muscle fibers by real time fluorescence microscopy.

Journal: Antioxidants & redox signaling 20080801

Title: Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic beta-cell line, MIN6.

Journal: Metabolism: clinical and experimental 20080801

Title: The impact of high anxiety level on the oxidative status of mouse peripheral blood lymphocytes, granulocytes and monocytes.

Journal: European journal of pharmacology 20080728

Title: Enhanced expression of Harvey ras induced by serum deprivation in cultured astrocytes.

Journal: Journal of neurochemistry 20080701

Title: Different effects of palmitoyl-L-carnitine and palmitoyl-CoA on mitochondrial function in rat ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20080701

Title: Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20080601

Title: Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes.

Journal: Life sciences 20080523

Title: Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20080513

Title: Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts.

Journal: International journal of molecular sciences 20080501

Title: L-N-Acetylcysteine protects against radiation-induced apoptosis in a cochlear cell line.

Journal: Acta oto-laryngologica 20080401

Title: The role of oxidative stress in acrolein-induced DNA damage in HepG2 cells.

Journal: Free radical research 20080401

Title: Modification to the Lampariello approach to evaluate reactive oxygen species production by flow cytometry.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080201

Title: Tanshinone IIA protects neonatal rat cardiomyocytes from adriamycin-induced apoptosis.

Journal: Translational research : the journal of laboratory and clinical medicine 20080201

Title: Sulfated glucosamine inhibits oxidation of biomolecules in cells via a mechanism involving intracellular free radical scavenging.

Journal: European journal of pharmacology 20080128

Title: Study of the synergistic effect on hepatoma 22 tumor cells by focused ultrasound activation of hematoporphyrin.

Journal: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 20080101

Title: Expression of cell surface receptors and oxidative metabolism modulation in the clinical continuum of sepsis.

Journal: Critical care (London, England) 20080101

Title: Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells.

Journal: Molecular vision 20080101

Title: The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells.

Journal: Comparative hepatology 20080101

Title: Bacterial and H2O2 stress-induced apoptosis-like events in Cryptococcus neoformans.

Journal: Research in microbiology 20080101

Title: Redox property of ribonucleotide reductase small subunit M2 and p53R2.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Method for conducting microarray study of oxidative stress induced gene expression.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Neurokinin-1 receptor activation induces reactive oxygen species and epithelial damage in allergic airway inflammation.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20071201

Title: Enhanced antigen delivery via cell death induced by the vaccine adjuvants.

Journal: Vaccine 20071107

Title: Ethanol induces apoptosis in hepatocytes by a pathway involving novel protein kinase C isoforms.

Journal: Cellular signalling 20071101

Title: Measurement of reactive species production by nanoparticles prepared in biologically relevant media.

Journal: Toxicology letters 20071101

Title: A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche.

Journal: Blood 20071015

Title: Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F.

Journal: Free radical biology & medicine 20071015

Title: Antiaggregant effects of Arbutus unedo extracts in human platelets.

Journal: Journal of ethnopharmacology 20070905

Title: Mechanism of CATA3 induction by cadmium in sunflower leaves.

Journal: Plant physiology and biochemistry : PPB 20070801

Title: Benzene's metabolites alter c-MYB activity via reactive oxygen species in HD3 cells.

Journal: Toxicology and applied pharmacology 20070715

Title: Oxidative burst in hard clam (Mercenaria mercenaria) haemocytes.

Journal: Fish & shellfish immunology 20070701

Title: Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070701

Title: Carbon black particles increase reactive oxygen species formation in rat alveolar macrophages in vitro.

Journal: Archives of toxicology 20070601

Title: Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: Heparan sulfates mediate pressure-induced increase in lung endothelial hydraulic conductivity via nitric oxide/reactive oxygen species.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: The environmental carcinogen 3-nitrobenzanthrone and its main metabolite 3-aminobenzanthrone enhance formation of reactive oxygen intermediates in human A549 lung epithelial cells.

Journal: Toxicology and applied pharmacology 20070601

Title: Development of a fluorescence-based enzyme assay of human 5-lipoxygenase.

Journal: Analytical biochemistry 20070515

Title: Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis.

Journal: Toxicology and applied pharmacology 20070501

Title: Diverse subcellular locations of cryptogein-induced reactive oxygen species production in tobacco Bright Yellow-2 cells.

Journal: Plant physiology 20070401

Title: Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.

Journal: Current eye research 20070301

Title: Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease.

Journal: The Journal of biological chemistry 20070216

Title: ROS scavenging effects of organic extract of diesel exhaust particles on human neutrophil granulocytes and rat alveolar macrophages.

Journal: Toxicology 20070212

Title: Copper-1,10-phenanthroline-induced apoptosis in liver carcinoma Bel-7402 cells associates with copper overload, reactive oxygen species production, glutathione depletion and oxidative DNA damage.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20070201

Title: A necrotic cell death model in a protist.

Journal: Cell death and differentiation 20070201

Title: Postanoxic damage of microglial cells is mediated by xanthine oxidase and cyclooxygenase.

Journal: Free radical research 20070201

Title: Nicotine: the link between cigarette smoking and the progression of renal injury?

Journal: American journal of physiology. Heart and circulatory physiology 20070101

Title: Methyl tert-butyl ether (MTBE)-induced cytotoxicity and oxidative stress in isolated rat spermatogenic cells.

Journal: Journal of applied toxicology : JAT 20070101

Title: Macelignan protects HepG2 cells against tert-butylhydroperoxide-induced oxidative damage.

Journal: BioFactors (Oxford, England) 20070101

Title: Platelet-derived exosomes induce endothelial cell apoptosis through peroxynitrite generation: experimental evidence for a novel mechanism of septic vascular dysfunction.

Journal: Critical care (London, England) 20070101

Title: Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation.

Journal: Cancer research 20061215

Title: (+/-)-2-Chloropropionic acid elevates reactive oxygen species formation in human neutrophil granulocytes.

Journal: Toxicology 20061207

Title: TNFalpha-induced cytoprotection requires the production of free radicals within mitochondria in C2C12 myotubes.

Journal: Life sciences 20061102

Title: The effect of hyperoxia on reactive oxygen species (ROS) in rat petrosal ganglion neurons during development using organotypic slices.

Journal: Pediatric research 20061001

Title: The antioxidant role of a reagent, 2',7'-dichlorodihydrofluorescin diacetate, detecting reactive-oxygen species and blocking the induction of heme oxygenase-1 and preventing cytotoxicity.

Journal: Journal of biochemistry 20061001

Title: Application of lipid peroxidation and protein oxidation biomarkers for oxidative damage in mammalian cells. A comparison with two fluorescent probes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060901

Title: Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.

Journal: Chemico-biological interactions 20060825

Title: Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801

Title: Fluoroquinolone eye drop-induced cytotoxicity: role of preservative in P2X7 cell death receptor activation and apoptosis.

Journal: Investigative ophthalmology & visual science 20060701

Title: Screening the oxidative potential of several mono- and di-halogenated biphenyls and biphenyl ethers in rat hepatocytes.

Journal: Combinatorial chemistry & high throughput screening 20060701

Title: Relationship between oxidative stress levels and activation state on a hepatic stellate cell line.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20060501

Title: Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species.

Journal: Journal of hypertension 20060401

Title: Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes.

Journal: Acta pharmacologica Sinica 20060401

Title: The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy?

Journal: Free radical biology & medicine 20060315

Title: Effect of N-acetyl-L-cysteine on ROS production and cell death caused by HEMA in human primary gingival fibroblasts.

Journal: Biomaterials 20060301

Title: Astrocyte control of fetal cortical neuron glutathione homeostasis: up-regulation by ethanol.

Journal: Journal of neurochemistry 20060301

Title: Fetal hemoglobin induction by histone deacetylase inhibitors involves generation of reactive oxygen species.

Journal: Experimental hematology 20060301

Title: Dose-dependent effect of hydrogen peroxide on calcium mobilization in mouse pancreatic acinar cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201

Title: Delta opioid agonists attenuate TAT(1-72)-induced oxidative stress in SK-N-SH cells.

Journal: Neurotoxicology 20060101

Title: Estrogen attenuates gp120- and tat1-72-induced oxidative stress and prevents loss of dopamine transporter function.

Journal: Synapse (New York, N.Y.) 20060101

Title: Manganese superoxide dismutase protects from TNF-alpha-induced apoptosis by increasing the steady-state production of H2O2.

Journal: Antioxidants & redox signaling 20060101

Title: Development to the blastocyst stage, the oxidative state, and the quality of early developmental stage of porcine embryos cultured in alteration of glucose concentrations in vitro under different oxygen tensions.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Mechanisms of homocysteine-induced oxidative stress.

Journal: American journal of physiology. Heart and circulatory physiology 20051201

Title: Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1.

Journal: Oncogene 20051201

Title: Essential role of Rac1/NADPH oxidase in nerve growth factor induction of TRPV1 expression.

Journal: Journal of neurochemistry 20051201

Title: Total antioxidant capacity is impaired in different structures from aged rat brain.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20051201

Title: Effect of CO2 supply on formation of reactive oxygen species in Arabidopsis thaliana.

Journal: Protoplasma 20051201

Title: Light-induced decrease in DCF fluorescence of wheat leaves in the presence of salicyl hydroxamate.

Journal: Protoplasma 20051201

Title: Protective effect of KR-31378 on oxidative stress in cardiac myocytes.

Journal: Archives of pharmacal research 20051201

Title: Changes in superoxide dismutase activity and peroxynitrite content in rat peritoneal macrophages exposed to He-Ne laser radiation.

Journal: Biochemistry. Biokhimiia 20051201

Title: Synergistic effects of iron and aluminum on stress-related gene expression in primary human neural cells.

Journal: Journal of Alzheimer's disease : JAD 20051101

Title: Three-state 2',7'-difluorofluorescein excited-state proton transfer reactions in moderately acidic and very acidic media.

Journal: The journal of physical chemistry. A 20051006

Title: Involvement of oxygen free radicals in the serum-mediated increase of benzoquinone genotoxicity.

Journal: Environmental and molecular mutagenesis 20051001

Title: Distinct response to ionizing radiation of human prostate cell lines.

Journal: Oncology reports 20051001

Title: Intracellular generation of reactive oxygen species by contracting skeletal muscle cells.

Journal: Free radical biology & medicine 20050901

Title: Cyclosporin A generates superoxide in smooth muscle cells.

Journal: Free radical research 20050901

Title: Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement.

Journal: Free radical biology & medicine 20050815

Title: Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells.

Journal: American journal of physiology. Heart and circulatory physiology 20050801

Title: Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050801

Title: Effects of naphthalene quinonoids on the induction of oxidative DNA damage and cytotoxicity in calf thymus DNA and in human cultured cells.

Journal: Chemical research in toxicology 20050801

Title: NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.

Journal: American journal of physiology. Renal physiology 20050601

Title: DDT-induced oxidative damage in human blood mononuclear cells.

Journal: Environmental research 20050601

Title: Protective effects of panduratin A against oxidative damage of tert-butylhydroperoxide in human HepG2 cells.

Journal: Biological & pharmaceutical bulletin 20050601

Title: Up-regulation of gamma-glutamyl transpeptidase (GGT) activity in growth perturbed C6 astrocytes.

Journal: Brain research. Molecular brain research 20050520

Title: Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells.

Journal: Annals of the New York Academy of Sciences 20050501

Title: Translocation of Bax in rat hepatocytes cultured with ferric nitrilotriacetate.

Journal: Life sciences 20050429

Title: Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells.

Journal: Journal of cellular biochemistry 20050415

Title: Time course and role of the pineal gland in photoperiod control of innate immune cell functions in male Siberian hamsters.

Journal: Journal of neuroimmunology 20050401

Title: Effect of acute and chronic psychostimulant drugs on redox status, AP-1 activation and pro-enkephalin mRNA in the human astrocyte-like U373 MG cells.

Journal: Neuropharmacology 20050401

Title: [Inducement effect of (DIPP-L-Trp)2-L-Lys-OCH3 on apoptosis of K562 cells through mitochondrial-dependent pathway].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20050401

Title: Protective effect of diallyl disulfide on oxidative stress-injured neuronally differentiated PC12 cells.

Journal: Brain research. Molecular brain research 20050218

Title: Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-alpha and phorbol ester in human endothelial cells.

Journal: Cardiovascular research 20050215

Title: Absorption and emission study of 2',7'-difluorofluorescein and its excited-state buffer-mediated proton exchange reactions.

Journal: The journal of physical chemistry. A 20050210

Title: Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation.

Journal: Endocrinology 20050201

Title: c-Src and hydrogen peroxide mediate transforming growth factor-beta1-induced smooth muscle cell-gene expression in 10T1/2 cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050201

Title: Cytotoxic effects induced by oxidative stress in cultured mammalian cells and protection provided by Hsp27 expression.

Journal: Methods (San Diego, Calif.) 20050201

Title: Sulfonylurea as well as elevated glucose levels stimulate reactive oxygen species production in the pancreatic beta-cell line, MIN6-a role of NAD(P)H oxidase in beta-cells.

Journal: Biochemical and biophysical research communications 20050107

Title: N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress.

Journal: Free radical biology & medicine 20050101

Title: Caloric restriction augments ROS defense in S. cerevisiae, by a Sir2p independent mechanism.

Journal: Free radical research 20050101

Title: Inhibition of influenza-virus-induced apoptosis in chorion cells of human fetal membranes by nordihydroguaiaretic Acid.

Journal: Intervirology 20050101

Title: Antioxidant effect of hydroxytyrosol, a polyphenol from olive oil: scavenging of hydrogen peroxide but not superoxide anion produced by human neutrophils.

Journal: Biochemical pharmacology 20041115

Title: Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041101

Title: Lack of in vitro protection by a common sunscreen ingredient on UVA-induced cytotoxicity in keratinocytes.

Journal: Toxicology 20041015

Title: Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.

Journal: British journal of pharmacology 20041001

Title: Release of calcium from intracellular stores and subsequent uptake by mitochondria are essential for the candidacidal activity of an N-terminal peptide of human lactoferrin.

Journal: The Journal of antimicrobial chemotherapy 20040901

Title: Human neuroblastoma (SH-SY5Y) cells are highly sensitive to the lysosomotropic aldehyde 3-aminopropanal.

Journal: Brain research 20040806

Title: Active oxygen chemistry within the liposomal bilayer. Part IV: Locating 2',7'-dichlorofluorescein (DCF), 2',7'-dichlorodihydrofluorescein (DCFH) and 2',7'-dichlorodihydrofluorescein diacetate (DCFH-DA) in the lipid bilayer.

Journal: Chemistry and physics of lipids 20040801

Title: SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I.

Journal: Annals of neurology 20040801

Title: Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells.

Journal: Biochemical pharmacology 20040715

Title: The influence of small oligosaccharides on the immune system.

Journal: Carbohydrate research 20040712

Title: Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells.

Journal: Brain research 20040529

Title: Methylglyoxal induces oxidative stress-dependent cell injury and up-regulation of interleukin-1beta and nerve growth factor in cultured hippocampal neuronal cells.

Journal: Brain research 20040501

Title: Oxidative stress and mitochondrial glutathione in human lymphocytes exposed to clinically relevant anesthetic drug concentrations.

Journal: Journal of clinical anesthesia 20040501

Title: Zn2+-induced cell death is mediated by the induction of intracellular ROS in ARPE-19 cells.

Journal: Current eye research 20040301

Title: Antioxidant effects of American ginseng berry extract in cardiomyocytes exposed to acute oxidant stress.

Journal: Biochimica et biophysica acta 20040224

Title: Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.

Journal: Journal of neurochemistry 20040201

Title: Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation.

Journal: Archives of pharmacal research 20040201

Title: Changes in oxidative balance in rat pericytes exposed to diabetic conditions.

Journal: Journal of cellular and molecular medicine 20040101

Title: An in vitro procedure for evaluation of early stage oxidative stress in an established fish cell line applied to investigation of PHAH and pesticide toxicity.

Journal: Marine environmental research 20040101

Title: Scoparia dulcis, a traditional antidiabetic plant, protects against streptozotocin induced oxidative stress and apoptosis in vitro and in vivo.

Journal: Journal of biochemical and molecular toxicology 20040101

Title: 7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by increasing the production of reactive oxygen species.

Journal: Redox report : communications in free radical research 20040101

Title: Leptin stimulates the oxidative burst in control monocytes but attenuates the oxidative burst in monocytes from HIV-infected patients.

Journal: Clinical and experimental immunology 20031201

Title: Adaptation of the dichlorofluorescein assay for detection of radiation-induced oxidative stress in cultured cells.

Journal: Radiation research 20031201

Title: Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells.

Journal: The Biochemical journal 20031101

Title: Fluorescent labeling of yeast.

Journal: Current protocols in cell biology 20031101

Title: Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection.

Journal: Life sciences 20031017

Title: Reactive oxygen species mediate cyclooxygenase-2 induction during monocyte to macrophage differentiation: critical role of NADPH oxidase.

Journal: Cardiovascular research 20031015

Title: Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031001

Title: Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells.

Journal: Journal of cellular biochemistry 20031001

Title: Both calcium and ROS as common signals mediate Na(2)SeO(3)-induced apoptosis in SW480 human colonic carcinoma cells.

Journal: Journal of inorganic biochemistry 20031001

Title: Down-regulation of CYP1A2 induction during the maturation of mouse cerebellar granule cells in culture: role of nitric oxide accumulation.

Journal: The European journal of neuroscience 20031001

Title: Acquisition of heat shock tolerance by regulation of intracellular redox states.

Journal: Biochimica et biophysica acta 20030923

Title: Effects of midazolam on equine innate immune response: a flow cytometric study.

Journal: Veterinary immunology and immunopathology 20030915

Title: Upregulation of reactive oxygen species generation and phagocytosis, and increased apoptosis in human neutrophils during severe sepsis and septic shock.

Journal: Shock (Augusta, Ga.) 20030901

Title: Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions.

Journal: Free radical biology & medicine 20030901

Title: Antioxidant effect of flavonoids on DCF production in HL-60 cells.

Journal: Phytotherapy research : PTR 20030901

Title: Oxidative stress in HEp-2 human laryngeal carcinoma cells induced by combination of vitamins B12b and C.

Journal: Bulletin of experimental biology and medicine 20030901

Title: Inhibition of neutrophil migration and oxygen free radical release by metipranolol and timolol.

Journal: Pharmacology 20030801

Title: Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats.

Journal: Journal of the American Society of Nephrology : JASN 20030801

Title: Action of DCFH and BODIPY as a probe for radical oxidation in hydrophilic and lipophilic domain.

Journal: Free radical research 20030801

Title: Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle.

Journal: Free radical biology & medicine 20030701

Title: Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide.

Journal: American journal of respiratory cell and molecular biology 20030601

Title: Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation.

Journal: Biochemical pharmacology 20030515

Title: Flow cytometry study of polymorphonuclear neutrophil oxidative burst: a comparison of three fluorescent probes.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030501

Title: Oxidative damage to human lens epithelial cells in culture: estrogen protection of mitochondrial potential, ATP, and cell viability.

Journal: Investigative ophthalmology & visual science 20030501

Title: Inflammatory agonist stimulation and signal pathway of oxidative burst in neonatal chicken heterophils.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030501

Title: Reactive oxygen species mediate endotoxin-induced human dermal endothelial NF-kappaB activation.

Journal: The Journal of surgical research 20030501

Title: Optimisation of cell-based assays for medium throughput screening of oxidative stress.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030401

Title: Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells.

Journal: Antioxidants & redox signaling 20030401

Title: Flow cytometric measurement of reactive oxygen species production by normal and thalassaemic red blood cells.

Journal: European journal of haematology 20030201

Title: Up-regulation of aldose reductase by the substrate, methylglyoxal.

Journal: Chemico-biological interactions 20030201

Title: Subtoxic concentration of manganese synergistically potentiates 1-methyl-4-phenylpyridinium-induced neurotoxicity in PC12 cells.

Journal: Brain research 20030124

Title: [Effect of sanazole and metrinidazole on production of reactive oxygen species by macrophages].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Protective effect of human HDL against Cu(2+)-induced oxidation of astrocytes.

Journal: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20030101

Title: Mitochondrial reactive oxygen species regulate spatial profile of proinflammatory responses in lung venular capillaries.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20021215

Title: Time course assessment of methylmercury effects on C6 glioma cells: submicromolar concentrations induce oxidative DNA damage and apoptosis.

Journal: Journal of neuroscience research 20021201

Title: Effects of ovotransferrin on chicken macrophages and heterophil-granulocytes.

Journal: Developmental and comparative immunology 20021101

Title: Protective properties of artichoke (Cynara scolymus) against oxidative stress induced in cultured endothelial cells and monocytes.

Journal: Life sciences 20021101

Title: Neuroprotective effects of prostaglandin E2 or cAMP against microglial and neuronal free radical mediated toxicity associated with inflammation.

Journal: Journal of neuroscience research 20021001

Title: Semi-quantitative estimation of heme/hemoprotein with dichlorodihydrofluorescin diacetate.

Journal: Analytical biochemistry 20020915

Title: Resveratrol affects in a different way primary versus fixed DNA damage induced by H(2)O(2) in mammalian cells in vitro.

Journal: Toxicology letters 20020905

Title: Determination of the pH of the Cryptococcus neoformans vacuole.

Journal: Medical mycology 20020601

Title: Free radical scavenging properties of sulfinpyrazone.

Journal: Free radical research 20020601

Title: Altholactone, a novel styryl-lactone induces apoptosis via oxidative stress in human HL-60 leukemia cells.

Journal: Toxicology letters 20020528

Title: Is the neutrophil reactive oxygen species production measured by luminol and lucigenin chemiluminescence intra or extracellular? Comparison with DCFH-DA flow cytometry and cytochrome c reduction.

Journal: Clinica chimica acta; international journal of clinical chemistry 20020507

Title: Substrate-induced up-regulation of aldose reductase by methylglyoxal, a reactive oxoaldehyde elevated in diabetes.

Journal: Molecular pharmacology 20020501

Title: Fasting induces cyanide-resistant respiration and oxidative stress in the amoeba Chaos carolinensis: implications for the cubic structural transition in mitochondrial membranes.

Journal: Protoplasma 20020501

Title: Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi(m)) in pancreatic RINm5F cells: prevention by Bcl-2.

Journal: Molecular and cellular endocrinology 20020425

Title: Oxidative stress in glial cultures: detection by DAF-2 fluorescence used as a tool to measure peroxynitrite rather than nitric oxide.

Journal: Glia 20020415

Title: Role of glycine-33 and methionine-35 in Alzheimer's amyloid beta-peptide 1-42-associated oxidative stress and neurotoxicity.

Journal: Biochimica et biophysica acta 20020316

Title: Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS.

Journal: American journal of physiology. Heart and circulatory physiology 20020201

Title: Involvement of reactive oxygen species in the UV-B damage to the cyanobacterium Anabaena sp.

Journal: Journal of photochemistry and photobiology. B, Biology 20020201

Title: Acetylcholine attenuates cardiomyocyte oxidant stress during simulated ischemia and reoxygenation.

Journal: Pharmacology 20020101

Title: Assessment of oxidants in mitogen-activated protein kinase activation.

Journal: Methods in enzymology 20020101

Title: Flow cytometric determination of cytoplasmic oxidants and mitochondrial membrane potential in neuronal cells.

Journal: Methods in enzymology 20020101

Title: Different action of IBMX, isoproterenol and rutin on orthovanadate-induced nitric oxide release in mouse macrophage cells.

Journal: Acta veterinaria Hungarica 20020101

Title: Critical role of mitochondrial reactive oxygen species formation in visible laser irradiation-induced apoptosis in rat brain astrocytes (RBA-1).

Journal: Journal of biomedical science 20020101

Title: Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence.

Journal: Journal of biomedical science 20020101

Title: 17Beta-estradiol inhibits oxidized low density lipoprotein-induced generation of reactive oxygen species in endothelial cells.

Journal: Life sciences 20011214

Title: Oxidative stress in Ca(2+)-induced membrane permeability transition in brain mitochondria.

Journal: Journal of neurochemistry 20011201

Title: Detection of reactive oxygen and reactive nitrogen species in skeletal muscle.

Journal: Microscopy research and technique 20011115

Title: Ammonia-induced production of free radicals in primary cultures of rat astrocytes.

Journal: Journal of neuroscience research 20011015

Title: Mitochondrial perturbations and oxidant stress in lymphocytes from patients undergoing surgery and general anesthesia.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20011001

Title: In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.

Journal: The American journal of pathology 20010901

Title: Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells.

Journal: The Biochemical journal 20010501

Title: Reactive oxygen species modulate angiotensin II-induced beta-myosin heavy chain gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in neonatal rat cardiomyocytes.

Journal: Biochemical and biophysical research communications 20010427

Title: Induction of CDK inhibitors (p21(WAF1) and p27(Kip1)) and Bak in the beta-lapachone-induced apoptosis of human prostate cancer cells.

Journal: Molecular pharmacology 20010401

Title: The role of intracellular oxidation in death induction (apoptosis and necrosis) in human promonocytic cells treated with stress inducers (cadmium, heat, X-rays).

Journal: European journal of cell biology 20010401

Title: Immune complex stimulation of neutrophil apoptosis: investigating the involvement of oxidative and nonoxidative pathways.

Journal: Free radical biology & medicine 20010115

Title: Okadaic acid-induced upregulation of nitrotyrosine and heme oxygenase-1 in rat cortical neuron cultures.

Journal: Neuroscience letters 20010105

Title: Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.

Journal: Journal of molecular and cellular cardiology 20010101

Title: Antioxidant enzyme activity and oxidative stress in bovine oocyte in vitro maturation.

Journal: IUBMB life 20010101

Title: Intracellular generation of free radicals and modifications of detoxifying enzymes in cultured neurons from the developing rat forebrain in response to transient hypoxia.

Journal: Neuroscience 20010101

Title: Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease.

Journal: Respiratory research 20010101

Title: Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression.

Journal: Journal of cellular physiology 19980501

Title: Modulation of cellular antioxidant defense activities by sodium arsenite in human fibroblasts.

Journal: Archives of toxicology 19950101

Title: Mitochondrial regulation of superoxide by Ca2+: an alternate mechanism for the cardiotoxicity of doxorubicin.

Journal: Toxicology and applied pharmacology 19910101

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Tags:2044-85-1 Molecular Formula|2044-85-1 MDL|2044-85-1 SMILES|2044-85-1 2',7'-Dichlorofluorescein diacetate