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2051-62-9,MFCD00013640
Catalog No.:AA0029S4

2051-62-9 | 4-Chlorobiphenyl

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1g
95%
in stock  
$32.00   $23.00
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5g
95%
in stock  
$104.00   $73.00
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25g
95%
in stock  
$381.00   $267.00
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100g
98%
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$1,208.00   $846.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0029S4
Chemical Name:
4-Chlorobiphenyl
CAS Number:
2051-62-9
Molecular Formula:
C12H9Cl
Molecular Weight:
188.6529
MDL Number:
MFCD00013640
SMILES:
Clc1ccc(cc1)c1ccccc1
NSC Number:
37066
UN Number:
3432
Properties
Computed Properties
 
Complexity:
141  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Rotatable Bond Count:
1  
XLogP3:
4.6  

Literature

Title: Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes.

Journal: Archives of toxicology 20160201

Title: Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes.

Journal: Toxicology letters 20150318

Title: Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1.

Journal: Chemico-biological interactions 20140405

Title: Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin.

Journal: Environmental health perspectives 20130601

Title: [4-chlorobiphenyl and 4-chlorobenzoic acid biodegradation by Rhodococcus ruber P25].

Journal: Mikrobiologiia 20120101

Title: Antioxidant compounds improved PCB-degradation by Burkholderia xenovorans strain LB400.

Journal: Enzyme and microbial technology 20111210

Title: Are luminescent bacteria suitable for online detection and monitoring of toxic compounds in drinking water and its sources?

Journal: Analytical and bioanalytical chemistry 20110501

Title: Humic acid and metal ions accelerating the dechlorination of 4-chlorobiphenyl by nanoscale zero-valent iron.

Journal: Journal of environmental sciences (China) 20110101

Title: New hydroxylated metabolites of 4-monochlorobiphenyl in whole poplar plants.

Journal: Chemistry Central journal 20110101

Title: An efficient organocatalytic method for constructing biaryls through aromatic C-H activation.

Journal: Nature chemistry 20101201

Title: Induction of cytochrome P450 1A1 in MCF-7 human breast cancer cells by 4-chlorobiphenyl (PCB3) and the effects of its hydroxylated metabolites on cellular apoptosis.

Journal: Environment international 20101101

Title: Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites.

Journal: Environment international 20101101

Title: 2-(4-Chlorophenyl)benzo-1,4-quinone induced ROS-signaling inhibits proliferation in human non-malignant prostate epithelial cells.

Journal: Environment international 20101101

Title: Polyploidy-induction by dihydroxylated monochlorobiphenyls: structure-activity-relationships.

Journal: Environment international 20101101

Title: 3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats.

Journal: Environment international 20101101

Title: 4'-Chloro-biphenyl-3-yl 2,2,2-trichloro-ethyl sulfate.

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: Hydroxylated metabolites of 4-monochlorobiphenyl and its metabolic pathway in whole poplar plants.

Journal: Environmental science & technology 20100515

Title: The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments.

Journal: PloS one 20100101

Title: Computational framework for predictive biodegradation.

Journal: Biotechnology and bioengineering 20091215

Title: Direct inhibition of ERK1/2 phosphorylation as a possible mechanism for the antiproliferative action of 3,4-diOH-PCB3 in the MCF-7 cell line.

Journal: Toxicology letters 20091028

Title: Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells.

Journal: Toxicology and applied pharmacology 20091015

Title: Kinetic study of hydrodechlorination of chlorobiphenyl with polymer-stabilized palladium nanoparticles in supercritical carbon dioxide.

Journal: The journal of physical chemistry. A 20090910

Title: Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques.

Journal: European journal of medicinal chemistry 20090501

Title: Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase.

Journal: Chemical research in toxicology 20090101

Title: Novel Tn4371-ICE like element in Ralstonia pickettii and genome mining for comparative elements.

Journal: BMC microbiology 20090101

Title: Reductive Dechlorination of Polychlorinated Biphenyls and Dibenzo-p-Dioxins in an Enrichment Culture Containing Dehalobacter Species.

Journal: Microbes and environments 20090101

Title: 4'-Chloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate.

Journal: Acta crystallographica. Section E, Structure reports online 20081201

Title: Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells.

Journal: Free radical biology & medicine 20081015

Title: Microbial transformation and degradation of polychlorinated biphenyls.

Journal: Environmental pollution (Barking, Essex : 1987) 20080901

Title: A low halogenated biphenyl (PCB3) increases CYP1A1 expression and activity via the estrogen receptor beta in the porcine ovary.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901

Title: Semiquinone radicals from oxygenated polychlorinated biphenyls: electron paramagnetic resonance studies.

Journal: Chemical research in toxicology 20080721

Title: Xenobiotic geometry and media pH determine cytotoxicity through solubility.

Journal: Chemical research in toxicology 20080501

Title: Mutagenicity of 3-methylcholanthrene, pcb3, and 4-oh-pcb3 in the lung of transgenic bigblue rats.

Journal: Environmental toxicology and pharmacology 20080301

Title: Effects of estradiol, PCB3, and their hydroxylated metabolites on proliferation, cell cycle, and apoptosis of human breast cancer cells.

Journal: Environmental toxicology and pharmacology 20080301

Title: The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae.

Journal: BMC genomics 20080101

Title: Degradation and mineralization of 2-chloro-, 3-chloro- and 4-chlorobiphenyl by a newly characterized natural bacterial strain isolated from an electrical transformer fluid-contaminated soil.

Journal: Journal of environmental sciences (China) 20080101

Title: Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range.

Journal: Biochemistry 20071218

Title: Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071101

Title: Expression of bacterial biphenyl-chlorobiphenyl dioxygenase genes in tobacco plants.

Journal: Biotechnology and bioengineering 20070615

Title: Pathways and products of the degradation of PCBs by the sodium dispersion method.

Journal: Chemosphere 20070601

Title: Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes.

Journal: Chemico-biological interactions 20070501

Title: Electrocatalytic hydrodechlorination of 4-chlorobiphenyl in aqueous solution using palladized nickel foam cathode.

Journal: Chemosphere 20070401

Title: Influence of fluoro-substitution on the planarity of 4-chlorobiphenyl (PCB 3).

Journal: Acta crystallographica. Section B, Structural science 20070401

Title: Characterization of two biphenyl dioxygenases for biphenyl/PCB degradation in A PCB degrader, Rhodococcus sp. strain RHA1.

Journal: Bioscience, biotechnology, and biochemistry 20070401

Title: 4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats.

Journal: Carcinogenesis 20070201

Title: Response to (chloro)biphenyls of the polychlorobiphenyl-degrader Burkholderia xenovorans LB400 involves stress proteins also induced by heat shock and oxidative stress.

Journal: FEMS microbiology letters 20070201

Title: [Estimation of bioconcentration factor of benzene derivatives].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20061201

Title: Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary.

Journal: Toxicology letters 20061025

Title: Oxidative ring cleavage of low chlorinated biphenyl derivatives by fungi leads to the formation of chlorinated lactone derivatives.

Journal: Chemosphere 20060701

Title: In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity.

Journal: Toxicology letters 20060701

Title: Characterization of the PCB substrate range of microbial dechlorination process LP.

Journal: Environmental science & technology 20050901

Title: Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.

Journal: Journal of medicinal chemistry 20050602

Title: Elucidation of degradation mechanism of dioxins during mechanochemical treatment.

Journal: Environmental science & technology 20050515

Title: Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

Journal: Journal of medicinal chemistry 20050127

Title: Comparison of the actions of 4-chlorobiphenyl and its hydroxylated metabolites on estradiol secretion by ovarian follicles in primary cells in culture.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: Effect of sorbate planarity on environmental black carbon sorption.

Journal: Environmental science & technology 20040701

Title: Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501

Title: Construction of transformant reporters carrying fused genes using pcbC promoter of Pseudomonas sp DJ-12 for detection of aromatic pollutants.

Journal: Environmental monitoring and assessment 20040301

Title: [Determination of tanshinone IIA in rat plasma and the pharmacokinetics by RP-HPLC method].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030501

Title: Binding of polychlorinated biphenyls/metabolites to hemoglobin.

Journal: Toxicology letters 20030430

Title: DNA adducts in cultures of polychlorinated biphenyl-treated human hepatocytes.

Journal: Toxicology and applied pharmacology 20030415

Title: DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites.

Journal: Chemico-biological interactions 20020220

Title: Sonochemical desorption and destruction of 4-chlorobiphenyl from synthetic sediments.

Journal: Environmental science & technology 20020115

Title: A laboratory pilot study of thermal decontamination of soils polluted by PCBs. Comparison with thermogravimetric analysis.

Journal: Waste management (New York, N.Y.) 20020101

Title: Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice.

Journal: Chemico-biological interactions 20010928

Title: Adaptive and cross-protective responses of Pseudomonas sp. DJ-12 to several aromatics and other stress shocks.

Journal: Current microbiology 20010901

Title: Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress.

Journal: Biochemical pharmacology 20010801

Title: Dechlorination of polychlorobiphenyls using NaBH(4) and NaBH(4)/LiCl at 120-310 degrees C in glyme solvents.

Journal: Journal of hazardous materials 20010420

Title: 2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity.

Journal: Molecular carcinogenesis 20010401

Title: Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver.

Journal: Toxicology and applied pharmacology 20010301

Title: Development of a Rhodococcus recombinant strain for degradation of products from anaerobic dechlorination of PCBs.

Journal: Environmental science & technology 20010215

Title: Dissemination of catabolic plasmids among desiccation-tolerant bacteria in soil microcosms.

Journal: Applied biochemistry and biotechnology 20010101

Title: A meta cleavage pathway for 4-chlorobenzoate, an intermediate in the metabolism of 4-chlorobiphenyl by Pseudomonas cepacia P166.

Journal: Applied and environmental microbiology 19950201

Title: Enhanced biodegradation of polychlorinated biphenyls after site-directed mutagenesis of a biphenyl dioxygenase gene.

Journal: Applied and environmental microbiology 19931101

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