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20559-55-1,MFCD00133728
Catalog No.:AA002A5Y

20559-55-1 | Oxibendazole

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10mg
98%
in stock  
$6.00   $4.00
- +
50mg
98%
in stock  
$9.00   $7.00
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100mg
98%
in stock  
$12.00   $8.00
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250mg
98%
in stock  
$14.00   $10.00
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1g
98%
in stock  
$25.00   $18.00
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25g
98%
in stock  
$232.00   $163.00
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100g
98%
in stock  
$775.00   $543.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002A5Y
Chemical Name:
Oxibendazole
CAS Number:
20559-55-1
Molecular Formula:
C12H15N3O3
Molecular Weight:
249.2658
MDL Number:
MFCD00133728
SMILES:
CCCOc1ccc2c(c1)[nH]c(n2)NC(=O)OC
NSC Number:
758459
Properties
Computed Properties
 
Complexity:
288  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
2.4  

Literature

Title: Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.

Journal: Scientific reports 20140101

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Development of an Evidence biochip array kit for the multiplex screening of more than 20 anthelmintic drugs.

Journal: Analytical and bioanalytical chemistry 20120701

Title: Further evaluation in field tests of the activity of three anthelmintics (fenbendazole, oxibendazole, and pyrantel pamoate) against the ascarid Parascaris equorum in horse foals on eight farms in Central Kentucky (2009-2010).

Journal: Parasitology research 20111001

Title: Potential drug development candidates for human soil-transmitted helminthiases.

Journal: PLoS neglected tropical diseases 20110601

Title: Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.

Journal: Archives of toxicology 20110301

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes.

Journal: BMC veterinary research 20100101

Title: Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Species-specific identification of equine cyathostomes resistant to fenbendazole and susceptible to oxibendazole and moxidectin by macroarray probing.

Journal: Experimental parasitology 20090101

Title: Equine cyathostomins: a review of biology, clinical significance and therapy.

Journal: Parasites & vectors 20090101

Title: Anthelmintic resistance in cyathostomin populations from horse yards in Italy, United Kingdom and Germany.

Journal: Parasites & vectors 20090101

Title: Determination of genomic DNA sequences for beta-tubulin isotype 1 from multiple species of cyathostomin and detection of resistance alleles in third-stage larvae from horses with naturally acquired infections.

Journal: Parasites & vectors 20090101

Title: Restrictions of anthelmintic usage: perspectives and potential consequences.

Journal: Parasites & vectors 20090101

Title: Diagnosis and control of anthelmintic-resistant Parascaris equorum.

Journal: Parasites & vectors 20090101

Title: The little-known scenario of anthelmintic resistance in equine cyathostomes in Italy.

Journal: Annals of the New York Academy of Sciences 20081201

Title: Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007.

Journal: Parasitology research 20080701

Title: Field studies indicating reduced activity of ivermectin on small strongyles in horses on a farm in Central Kentucky.

Journal: Parasitology research 20080601

Title: Study (1991 to 2001) of drug-resistant Population B small strongyles in critical tests in horses in Kentucky at the termination of a 40-year investigation.

Journal: Parasitology research 20070801

Title: Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically.

Journal: Parasitology research 20070201

Title: Field studies on endoparasites of Thoroughbred foals on seven farms in central Kentucky in 2004.

Journal: Parasitology research 20060401

Title: Comparative study of sample preparation methods; supported liquid membrane and solid phase extraction in the determination of benzimidazole anthelmintics in biological matrices by liquid chromatography-electrospray-mass spectrometry.

Journal: Talanta 20060315

Title: Prevalence of anthelmintic resistant cyathostomes on horse farms.

Journal: Journal of the American Veterinary Medical Association 20040915

Title: Evaluation of a larval development assay (DrenchRite) for the detection of anthelmintic resistance in cyathostomin nematodes of horses.

Journal: Veterinary parasitology 20040507

Title: Quantitative chromatographic determination of several benzimidazole anthelmintic molecules in parasite material.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031205

Title: Population-S benzimidazole- and tetrahydropyrimidine-resistant small strongyles in a pony herd in Kentucky (1977-1999): effects of anthelmintic treatment on the parasites as determined in critical tests.

Journal: Parasitology research 20031101

Title: Transtegumental diffusion of benzimidazole anthelmintics into Moniezia benedeni: correlation with their octanol-water partition coefficients.

Journal: Experimental parasitology 20030101

Title: An introductory survey of helminth control practices in south africa and anthelmintic resistance on Thoroughbred stud farms in the Western Cape Province.

Journal: Journal of the South African Veterinary Association 20021201

Title: Development and validation of a liquid chromatographic-electrospray tandem mass spectrometric multiresidue method for anthelmintics in milk.

Journal: Journal of chromatography. A 20021108

Title: HPLC assay for albendazole and metabolites in human plasma for clinical pharmacokinetic studies.

Journal: Journal of pharmaceutical and biomedical analysis 20021015

Title: One season of pasture exposure fails to induce a protective resistance to cyathostomes but increases numbers of hypobiotic third-stage larvae.

Journal: The Journal of parasitology 20020801

Title: Evaluation of tests for anthelmintic resistance in cyathostomes.

Journal: Veterinary parasitology 20020702

Title: Plasma disposition, faecal excretion and in vitro metabolism of oxibendazole following oral administration in horses.

Journal: Research in veterinary science 20020201

Title: Continuance of studies on Population S benzimidazole-resistant small strongyles in a Shetland pony herd in Kentucky: effect of pyrantel pamoate (1992-1999).

Journal: Veterinary parasitology 20010120

Title: Ultrastructural changes in Ascaris suum after oxibendazole treatment.

Journal: African journal of health sciences 19980201

Title: In vitro susceptibilities of the AIDS-associated microsporidian Encephalitozoon intestinalis to albendazole, its sulfoxide metabolite, and 12 additional benzimidazole derivatives.

Journal: Antimicrobial agents and chemotherapy 19971201

Title: Activity of benzimidazoles against cryptosporidiosis in neonatal BALB/c mice.

Journal: The Journal of parasitology 19951001

Title: Susceptibility of Encephalitozoon cuniculi to several drugs in vitro.

Journal: Antimicrobial agents and chemotherapy 19950601

Title: In vitro susceptibility of the opportunistic fungus Cryptococcus neoformans to anthelmintic benzimidazoles.

Journal: Antimicrobial agents and chemotherapy 19940201

Title: Hahyun Park , et al.Oxibendazole induces apoptotic cell death in proliferating porcine trophectoderm and uterine luminal epithelial cells via mitochondria-mediated calcium disruption and breakdown of mitochondrial membrane potential. Comp Biochem Physiol C Toxicol Pharmacol. 2019 Jun;220:9-19.

Title: Qiaoli Chen, et al. Oxibendazole inhibits prostate cancer cell growth. Oncol Lett. 2018 Feb;15(2):2218-2226.

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