[1]OrganicandBiomolecularChemistry,2009,vol.7,p.1404-1409
Title: Human Y-Family DNA Polymerase κ Is More Tolerant to Changes in Its Active Site Loop than Its Ortholog Escherichia coli DinB.
Journal: Chemical research in toxicology 20171120
Title: Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance.
Journal: Chemical research in toxicology 20120820
Title: Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction.
Journal: Chemical communications (Cambridge, England) 20120714
Title: Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy.
Journal: Nature structural & molecular biology 20120601
Title: Gram-scale chemical synthesis of 2'-deoxynucleoside-5'-o-triphosphates.
Journal: Current protocols in nucleic acid chemistry 20120601
Title: A review of the virological efficacy of the 4 World Health Organization-recommended tenofovir-containing regimens for initial HIV therapy.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120315
Title: Simple and sensitive microRNA labeling by terminal deoxynucleotidyl transferase.
Journal: Acta biochimica et biophysica Sinica 20120201
Title: Simultaneous determination of deoxycytidine diphosphate and deoxycytidine triphosphate by capillary electrophoresis with transient isotachophoretic stacking: a sensitive monitoring method for ribonucleotide reductase activity.
Journal: Electrophoresis 20120201
Title: Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study.
Journal: Journal of translational medicine 20120101
Title: Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis.
Journal: Nephron extra 20120101
Title: Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis.
Journal: PloS one 20120101
Title: Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation.
Journal: PloS one 20120101
Title: The dUTPase enzyme is essential in Mycobacterium smegmatis.
Journal: PloS one 20120101
Title: Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.
Journal: PloS one 20120101
Title: Importance of the C2, N7, and C8 positions to the mutagenic potential of 8-Oxo-2'-deoxyguanosine with two A family polymerases.
Journal: Biochemistry 20111213
Title: HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
Journal: Nature 20111106
Title: Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response.
Journal: Cell and tissue research 20110501
Title: Limited dCTP availability accounts for mitochondrial DNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
Journal: PLoS genetics 20110301
Title: Bypass of N²-ethylguanine by human DNA polymerase κ.
Journal: DNA repair 20110102
Title: Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed.
Journal: Mobile DNA 20110101
Title: Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage.
Journal: PloS one 20110101
Title: Stimulation of growth of the human gastric pathogen Helicobacter pylori by atmospheric level of oxygen under high carbon dioxide tension.
Journal: BMC microbiology 20110101
Title: Susceptibility to primary angle closure glaucoma in Saudi Arabia: the possible role of mitochondrial DNA ancestry informative haplogroups.
Journal: Molecular vision 20110101
Title: Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma: genotype-phenotype correlation.
Journal: Molecular vision 20110101
Title: Pseudomonas syringae pv. actinidiae draft genomes comparison reveal strain-specific features involved in adaptation and virulence to Actinidia species.
Journal: PloS one 20110101
Title: High level expression of Acidothermus cellulolyticus β-1, 4-endoglucanase in transgenic rice enhances the hydrolysis of its straw by cultured cow gastric fluid.
Journal: Biotechnology for biofuels 20110101
Title: Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota.
Journal: The Journal of biological chemistry 20101224
Title: Molecular and biomorphometrical identification of ovine babesiosis in iran.
Journal: Iranian journal of parasitology 20101201
Title: Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes.
Journal: Bioconjugate chemistry 20101020
Title: Synthesis and early development of hexadecyloxypropylcidofovir: an oral antipoxvirus nucleoside phosphonate.
Journal: Viruses 20101001
Title: Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase.
Journal: Biochemistry 20100706
Title: Antiviral treatment of chronic hepatitis B virus (HBV) infections.
Journal: Viruses 20100601
Title: Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine.
Journal: Biochemistry 20100309
Title: Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells.
Journal: Carcinogenesis 20100301
Title: Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.
Journal: Journal of molecular biology 20100205
Title: Specific amino acid residues are involved in substrate discrimination and template binding of human REV1 protein.
Journal: Biochemical and biophysical research communications 20100205
Title: Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells.
Journal: BMC biology 20100101
Title: Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts.
Journal: Cancer cell international 20100101
Title: In vivo trans-specific gene silencing in fungal cells by in planta expression of a double-stranded RNA.
Journal: BMC biology 20100101
Title: Cotylenin A inhibits cell proliferation and induces apoptosis and PAX6 mRNA transcripts in retinoblastoma cell lines.
Journal: Molecular vision 20100101
Title: Nelarabine in the treatment of refractory T-cell malignancies.
Journal: Clinical Medicine Insights. Oncology 20100101
Title: Clinical and genetic characterization of a Danish family with North Carolina macular dystrophy.
Journal: Molecular vision 20100101
Title: Single-nucleotide and long-patch base excision repair of DNA damage in plants.
Journal: The Plant journal : for cell and molecular biology 20091101
Title: Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme.
Journal: The Journal of biological chemistry 20090925
Title: Amino acid architecture that influences dNTP insertion efficiency in Y-family DNA polymerase V of E. coli.
Journal: Journal of molecular biology 20090918
Title: Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Journal: Antimicrobial agents and chemotherapy 20090901
Title: Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
Journal: The Biochemical journal 20090827
Title: Fishing in the (deoxyribonucleotide) pool.
Journal: The Biochemical journal 20090827
Title: Structure of the human Rev1-DNA-dNTP ternary complex.
Journal: Journal of molecular biology 20090724
Title: Development of a sensitive and selective LC/MS/MS method for the simultaneous determination of intracellular 1-beta-D-arabinofuranosylcytosine triphosphate (araCTP), cytidine triphosphate (CTP) and deoxycytidine triphosphate (dCTP) in a human follicular lymphoma cell line.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090515
Title: Y-Family DNA polymerases may use two different dNTP shapes for insertion: a hypothesis and its implications.
Journal: Journal of molecular graphics & modelling 20090401
Title: The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase.
Journal: Biochemistry 20090317
Title: Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
Journal: The Journal of biological chemistry 20090206
Title: Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine.
Journal: PloS one 20090101
Title: Paclitaxel alters the expression and specific activity of deoxycytidine kinase and cytidine deaminase in non-small cell lung cancer cell lines.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia.
Journal: OncoTargets and therapy 20090101
Title: Global hypomethylation of genomic DNA in cancer-associated myofibroblasts.
Journal: Cancer research 20081201
Title: Gemcitabine and taxanes in metastatic breast cancer: a systematic review.
Journal: Therapeutics and clinical risk management 20081201
Title: Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
Journal: Journal of molecular biology 20081003
Title: Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa.
Journal: Investigative ophthalmology & visual science 20080901
Title: Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1.
Journal: The Journal of biological chemistry 20080829
Title: Development of bioluminescent pyrophosphate assay using pyruvate phosphate dikinase and its application to single-nucleotide polymorphism analysis.
Journal: Analytical biochemistry 20080801
Title: Altered order of substrate binding by DNA polymerase X from African Swine Fever virus.
Journal: Biochemistry 20080729
Title: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Journal: The FEBS journal 20080501
Title: Nuclear magnetic resonance investigation of primer--template models: formation of a pyrimidine bulge upon misincorporation.
Journal: Biochemistry 20080415
Title: Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+.
Journal: Journal of molecular biology 20080314
Title: Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis.
Journal: Journal of molecular biology 20080215
Title: Structural insights into DNA lesion bypass.
Journal: Structure (London, England : 1993) 20080201
Title: Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase.
Journal: Structure (London, England : 1993) 20080201
Title: 2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.
Journal: The Journal of biological chemistry 20080125
Title: Glutathione S-transferase M1 and T1 polymorphisms in Arab glaucoma patients.
Journal: Molecular vision 20080101
Title: Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order.
Journal: Comparative and functional genomics 20080101
Title: A new linker group for functionalization of nucleic acids.
Journal: Nucleic acids symposium series (2004) 20080101
Title: Kinetics of dCTP incorporation opposite to 7,8-dihydro-8-oxoguanine with different 5' nearest neighbors by yeast polymerase eta.
Journal: Nucleic acids symposium series (2004) 20080101
Title: Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta.
Journal: Science (New York, N.Y.) 20071109
Title: NMR investigation of primer-template models: structural effect of sequence downstream of a thymine template on mutagenesis in DNA replication.
Journal: Biochemistry 20070814
Title: Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.
Journal: Nature chemical biology 20070801
Title: Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances.
Journal: Human molecular genetics 20070615
Title: 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins.
Journal: Nature 20070531
Title: Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta.
Journal: Biophysical journal 20070501
Title: Purification, crystallization and preliminary crystallographic analysis of deoxyuridine triphosphate nucleotidohydrolase from Arabidopsis thaliana.
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20070501
Title: Structure-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity.
Journal: Journal of molecular biology 20070309
Title: Investigating the 'steric gate' of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids.
Journal: Biochemistry 20070227
Title: DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength.
Journal: FEBS letters 20070220
Title: Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides.
Journal: BMC structural biology 20070101
Title: Methylation-dependent fragment separation: novel analysis of 5-methyl cytosine by capillary electrophoresis of amplified DNA using PCR incorporation of chemically modified dCTP.
Journal: Nucleosides, nucleotides & nucleic acids 20070101
Title: Transfer of surface polymerase reaction products to a secondary platform with conservation of spatial registration.
Journal: Journal of the American Chemical Society 20060920
Title: Joint use of small-angle X-ray and neutron scattering to study biological macromolecules in solution.
Journal: European biophysics journal : EBJ 20060901
Title: Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa.
Journal: The Journal of biological chemistry 20060728
Title: Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest.
Journal: Journal of biochemistry 20060701
Title: Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota.
Journal: Nature structural & molecular biology 20060701
Title: An efficiently extended class of unnatural base pairs.
Journal: Journal of the American Chemical Society 20060531
Title: Cellular pharmacology of gemcitabine.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060501
Title: Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.
Journal: The Journal of biological chemistry 20060127
Title: Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
Journal: PLoS biology 20060101
Title: Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway.
Journal: BMC cancer 20060101
Title: T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking.
Journal: BMC medical genetics 20060101
Title: E-selectin S128R polymorphism and severe coronary artery disease in Arabs.
Journal: BMC medical genetics 20060101
Title: Co-activator p120 is increased by gonadotropins in the rat ovary and enhances progesterone receptor activity.
Journal: Reproductive biology and endocrinology : RB&E 20060101
Title: The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.
Journal: British journal of cancer 20051212
Title: Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus.
Journal: The Journal of biological chemistry 20051209
Title: Transient state kinetic studies of the MutT-catalyzed nucleoside triphosphate pyrophosphohydrolase reaction.
Journal: Biochemistry 20051122
Title: In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant.
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Title: Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair.
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Title: Rev1 employs a novel mechanism of DNA synthesis using a protein template.
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Title: Four-color multiplex reverse transcription polymerase chain reaction--overcoming its limitations.
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Title: Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase.
Journal: RNA (New York, N.Y.) 20050901
Title: Comparison of functional properties of mammalian DNA polymerase lambda and DNA polymerase beta in reactions of DNA synthesis related to DNA repair.
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Title: Motions of the fingers subdomain of klentaq1 are fast and not rate limiting: implications for the molecular basis of fidelity in DNA polymerases.
Journal: Molecular cell 20050805
Title: Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate.
Journal: Biochemistry 20050802
Title: Release of DNA from dendriplexes encapsulated in PLGA nanoparticles.
Journal: International journal of pharmaceutics 20050725
Title: Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases.
Journal: Antiviral research 20050701
Title: Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues.
Journal: International journal of hematology 20050601
Title: Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.
Journal: Biochemistry 20050503
Title: Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site.
Journal: Biochemistry 20050308
Title: A new highly efficient photoreactive analogue of dCTP. Synthesis, characterization, and application in photoaffinity modification of DNA binding proteins.
Journal: Bioconjugate chemistry 20050101
Title: Comparison study on PCR amplification of modified DNA by using various kinds of polymerase and modified nucleoside triphosphates.
Journal: Nucleic acids symposium series (2004) 20050101
Title: Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.
Journal: Journal of the International AIDS Society 20050101
Title: Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu.
Journal: Biochemistry 20041102
Title: Amidox, an inhibitor of ribonucleotide reductase, potentiates the action of Ara-C in HL-60 human promyelocytic leukemia cells.
Journal: Nucleosides, nucleotides & nucleic acids 20041001
Title: [Lamivudine therapy for chronic hepatitis B].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040801
Title: Enhancement by effectors and substrate nucleotides of R1-R2 interactions in Escherichia coli class Ia ribonucleotide reductase.
Journal: The Journal of biological chemistry 20040723
Title: Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1.
Journal: The Journal of biological chemistry 20040611
Title: 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylation.
Journal: Journal of medical genetics 20040601
Title: Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis.
Journal: European journal of biochemistry 20040601
Title: Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA.
Journal: Arthritis and rheumatism 20040501
Title: Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV.
Journal: Biochemistry 20040224
Title: Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.
Journal: Molecular pharmacology 20040201
Title: Frequency and voltage dependence of the dielectrophoretic trapping of short lengths of DNA and dCTP in a nanopipette.
Journal: Biophysical journal 20040201
Title: Inhibitors of CTP biosynthesis potentiate the anti-human immunodeficiency virus type 1 activity of 3TC in activated peripheral blood mononuclear cells.
Journal: Antiviral research 20040101
Title: Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools.
Journal: Clinical pharmacokinetics 20040101
Title: Melatonin promoted chemotaxins expression in lung epithelial cell stimulated with TNF-alpha.
Journal: Respiratory research 20040101
Title: Antisense radiotherapy: targeting full-size mdrl mRNA with 125I-labelled oligonucleotides.
Journal: International journal of radiation biology 20040101
Title: Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms.
Journal: Biochemistry 20031230
Title: Combination chemotherapy in advanced gastrointestinal cancers: ex vivo sensitivity to gemcitabine and mitomycin C.
Journal: British journal of cancer 20031215
Title: Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA.
Journal: The Journal of biological chemistry 20031107
Title: Cloning, expression, and purification of the His6-tagged hyper-thermostable dUTPase from Pyrococcus woesei in Escherichia coli: application in PCR.
Journal: Protein expression and purification 20030901
Title: Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii and its relation to other homotrimeric dUTPases.
Journal: The Journal of biological chemistry 20030725
Title: Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors.
Journal: Journal of molecular biology 20030627
Title: Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines.
Journal: British journal of cancer 20030616
Title: Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
Journal: The Journal of biological chemistry 20030523
Title: Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity.
Journal: The Journal of biological chemistry 20030502
Title: Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.
Journal: Biochemistry 20030304
Title: Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases.
Journal: Nucleosides, nucleotides & nucleic acids 20030301
Title: Zero-mode waveguides for single-molecule analysis at high concentrations.
Journal: Science (New York, N.Y.) 20030131
Title: Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.
Journal: FEBS letters 20021204
Title: Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase.
Journal: Antiviral research 20021201
Title: Excess dNTPs minimize RNA hydrolysis during reverse transcription.
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Title: A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase.
Journal: Biochemistry 20020813
Title: Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.
Journal: Biochemical pharmacology 20020801
Title: Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells.
Journal: Biochemical pharmacology 20020801
Title: Recovery of cyanine-dye nucleotide triphosphates.
Journal: Analytical biochemistry 20020615
Title: Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs.-host disease: the role of dGTP in antiproliferative action of BCX-1777.
Journal: International immunopharmacology 20020601
Title: Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.
Journal: International journal of cancer 20020401
Title: The genome of bacteriophage phiKZ of Pseudomonas aeruginosa.
Journal: Journal of molecular biology 20020315
Title: Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside.
Journal: Cell death and differentiation 20020201
Title: Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation.
Journal: Journal of molecular biology 20020125
Title: 2-Amino-7-deazaadenine forms stable base pairs with cytosine and thymine.
Journal: Bioorganic & medicinal chemistry letters 20020107
Title: Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line.
Journal: Leukemia research 20011001
Title: Identification of nucleotides with identical fluorescent labels based on fluorescence polarization in surfactant solutions.
Journal: Analytical chemistry 20010915
Title: Structures of complexes formed by HIV-1 reverse transcriptase at a termination site of DNA synthesis.
Journal: The Journal of biological chemistry 20010817
Title: Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair.
Journal: The Journal of biological chemistry 20010706
Title: Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs.
Journal: The Journal of biological chemistry 20010629
Title: Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC).
Journal: Biochemical pharmacology 20010615
Title: Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I.
Journal: Biochemistry 20010605
Title: The effect of DNA structure on the catalytic efficiency and fidelity of human DNA polymerase beta on templates with platinum-DNA adducts.
Journal: The Journal of biological chemistry 20010601
Title: Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide.
Journal: British journal of haematology 20010501
Title: Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP.
Journal: The Journal of biological chemistry 20010223
Title: DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change.
Journal: The Journal of biological chemistry 20010202
Title: In vivo DNA analysis.
Journal: Methods in molecular biology (Clifton, N.J.) 20010101
Title: [Reagents for modification of protein-nucleic acids complexes. II. Site-specific photomodification of DNA-polymerase beta complexes with primers elongated by the dCTP exo-N-substituted arylazido derivatives].
Journal: Bioorganicheskaia khimiia 20010101
Title: Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901
Title: Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein.
Journal: The Journal of general virology 19990301
Title: Lethal mutagenesis of HIV with mutagenic nucleoside analogs.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19990216
Title: Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.
Journal: Nucleic acids research 19990215
Title: Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy.
Journal: Nucleosides & nucleotides 19990101
Title: Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism.
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Title: Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity.
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Title: Palindromic oligonucleotide-directed enzymatic determination of 2'-deoxythymidine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate in human cells.
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Title: Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay.
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Title: Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea.
Journal: Antimicrobial agents and chemotherapy 19970201
Title: Chiral influences of feedback inhibition with dCTP on murine deoxycytidine kinase.
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Title: Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
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Title: Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs.
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Title: Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs.
Journal: Antiviral research 19931201
Title: Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses.
Journal: Journal of medicinal chemistry 19931112
Title: The biochemical basis for the differential anti-human immunodeficiency virus activity of two cis enantiomers of 2',3'-dideoxy-3'-thiacytidine.
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